CN101301026A - Premixing feed for livestock and poultry containing multivitamins and method for preparing the same - Google Patents
Premixing feed for livestock and poultry containing multivitamins and method for preparing the same Download PDFInfo
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Abstract
The invention provides a multivitamin premix feed for livestock and poultry and a preparation, relates to a premixing feed for livestock and poultry and the preparation thereof, especially to a preparation of a premixing feed capable of improving the water solubility of vitamins in the premixing feed. The method comprises the steps of respectively dissolving vitamin A, vitamin D3 and vitamin E with vegetable oil and ethanol, and respectively forming powdery beta-cyclodextrin inclusion compounds. The beta-cyclodextrin inclusion compounds are evenly mixed with vitamin B1, vitamin B2, vitamin B6, folic acid, calcium pantothenate and glucose to form a light yellow powdery product. Since the vitamin A, the vitamin D3 and the vitamin E in the prepared premixing feed are water-soluble, the premixing feed may be used for livestock and poultry in drinking manner, so that the livestock and poultry grow evenly. The use method not only reduces the labor intensity of poultry rearing, but also improves the feed reward and the cultivation benefit.
Description
Technical field
The present invention relates to a kind of livestock and poultry with premixed feed and preparation method thereof, particularly a kind ofly can improve the water miscible premixed feed preparation method of vitamin in the premixed feed.
Background technology
Before the present invention realizes,, the consumption demand of butcher cattle poultry product is increased year by year along with the raising of people's living standard.Therefore people progressively improve meat livestock and poultry species, and the marketing time of meat livestock and poultry is shortened greatly.But the raising of the meat livestock and poultry speed of growth, tend to cause meat livestock and poultry carcase quality to descend, its reason is that the quick growth of meat livestock and poultry makes itself to be increased greatly to the requirement of various vitamins, and the content of various vitamins can not satisfy the meat livestock and poultry needs of growth fast in the present meat animal and fowl fodder, make meat livestock and poultry produce vitamin-deficiency, not only restricted the raising of meat livestock and poultry production efficiency, also directly influenced the carcase quality of meat livestock and poultry, made livestock and poultry produce Various Kinds of Avitaminosis.For addressing the above problem, people adopt the mode of adding various vitamins in feed to improve the quality of production of meat livestock and poultry, but because vitamin A, vitamin D, vitamin E is water insoluble, the livestock and poultry that conventional method is produced are used the multivitamin premixed feed, mixing is in feed according to a certain percentage, this using method has not only increased culturist's labour intensity, the more important thing is that the feed overwhelming majority that present meat livestock and poultry are used is a pellet, because livestock and poultry are differed greatly with the granularity of multivitamin premixed feed and the granularity of pellet, so both very difficult mixings, be difficult to have at any time the multivitamin premixed feed that adds in the feed when causing livestock and poultry to search for food, making livestock and poultry that avitaminotic problem take place easily can not be resolved well, influence culture benefit, also caused waste simultaneously.
Summary of the invention
The objective of the invention is to contain multivitamin livestock and poultry with premixed feed and preparation method by providing a kind of, vitamin presents water-solublely in the multivitamin premixed feed, and then has solved the problem that exists in the above-mentioned background technology.Livestock and poultry are dissolved in the water with the multivitamin premixed feed drinks for livestock and poultry, this using method has not only reduced labour intensity, more solved livestock and poultry with multivitamin premixed feed and pellet because of granularity differs greatly can not mixing a difficult problem, solved livestock and poultry and be easy to generate avitaminotic problem.
For achieving the above object, the present invention adopts following technical scheme:
A. at room temperature predetermined amount of beta-cyclodextrin is joined in a certain amount of water, stir while adding, till beta-schardinger dextrin-no longer dissolves, behind solution left standstill, get the saturated solution that supernatant is made beta-schardinger dextrin-, stand-by.
B. 0～40 part of retinol1 is dissolved in 100 parts the vegetable oil, makes the oil solution of vitamin A; The oil solution of said vitamin A is at room temperature slowly splashed in 100 parts of above-mentioned beta-schardinger dextrin-saturated solutions made from the speed of 200 of per minutes, stir 4h while dripping with 600 rev/mins, put cold back and refrigerate 24h down at 8 ℃, filtering with microporous membrane with 0.45um, with sediment 60 ℃ of dryings 4 hours, dry thing is crossed 80 mesh sieves, gets the Benexate Hydrochloride of vitamin A.
C. with vitamin D
32～3 parts are dissolved in 30 part 95% the ethanolic solution, make vitamin D
3Ethanolic solution; With said vitamin D
3Ethanolic solution at room temperature slowly splash in 30 parts of above-mentioned beta-schardinger dextrin-saturated solutions made from the speed of 200 of per minutes, stir 4h while dripping with 600 rev/mins, put cold back and refrigerate 24h down at 8 ℃, filtering with microporous membrane with 0.45um, with 60 ℃ of dryings of sediment 4 hours, dry thing is crossed 80 mesh sieves, get vitamin D
3Benexate Hydrochloride.
D. 0.002～0.005 part of vitamin E is dissolved in 5 part 95% the ethanolic solution, makes the ethanolic solution of vitamin E; The ethanolic solution of vitamin E is at room temperature slowly splashed in 5 parts of above-mentioned beta-schardinger dextrin-saturated solutions made from the speed of 200 of per minutes, stir 4h while dripping with 600 rev/mins, put and put into refrigerator after cold at 8 ℃ of refrigeration 24h down, filtering with microporous membrane with 0.45um, with 60 ℃ of dryings of sediment 4 hours, dry thing is crossed 80 mesh sieves, get the Benexate Hydrochloride of vitamin E.
E. with Benexate Hydrochloride, the vitamin D of the above-mentioned vitamin A of making respectively
3Benexate Hydrochloride, the Benexate Hydrochloride and the Cobastab of vitamin E
10.5～3 parts, Cobastab
21～5 part, Cobastab
60.5～3 parts, 0.05～0.2 part in folic acid, 1～5 part of calcium pantothenate and meet 200～350 parts of mixings of glucose for oral use of Chinese veterinary drug allusion quotation version standard in 2005 get product.
In above-mentioned preparation method, the preferred values of every composition can be 25 parts of vitamin As, vitamin D
33 parts, 0.003 part of vitamin E, Cobastab
11 part, Cobastab
23 parts, Cobastab
62 parts, 0.1 part in folic acid, 3 parts of calcium pantothenates, 300 parts of glucose.
In the above-mentioned preparation method, described various vitamins, folic acid, calcium pantothenate are feed grade.Beta-schardinger dextrin-can be the commercially available product that Anhui Shanhe Medical Accessary Material Co., Ltd. produces.
Umber described in the said method is meant: when solid was measurement unit with g, the liquid correspondence was measurement unit with ml; When solid was measurement unit with kg, liquid was measurement unit with L, by that analogy.
It is pale yellow powder that the livestock and poultry made from above-mentioned inventive method are with the outward appearance of premixed feed finished product.
Beta-schardinger dextrin-described in the inventive method is a kind of cyclic oligomer sugar compounds, has special ring-type hollow cylinder type structure, internal diameter 0.7～0.8nm, can form inclusion compound with drug molecule under certain condition, result of study shows at present, after medicine and beta-schardinger dextrin-form inclusion compound, can significantly increase the solubility in water of insoluble drug.
The water-soluble experiment of product of the present invention: sample 1g, the 2g, 4g, 8g, 16g, the 32g that get the embodiment of the invention 6 respectively, add water 100ml stirring and dissolving, can get faint yellow transparent solution, with this solution lucifuge placement at room temperature 24 hours, solution still was transparence.
During use, be dissolved in ratio dissolving in the 2000ml water according to 1g finished product of the present invention after, drink for livestock and poultry and to get final product.
Experimental example 1
In May, 2006, Shandong plant raises 5000 of AA fryer, when beginning to 25 ages in days from brooding, finds the long uniformity of chicken all living creatures worse and worse, ataxia, rhinitis inflammation.Cut open the sick young main pathological change of inspection: alimentary canal, respiratory tract particularly have many canescence lesser tubercles on esophagus, crop, oral cavity, the nasal membrane, and the fusion that has is in blocks, form pseudomembrane.Through being diagnosed as vitamin(e) A deficiency.Then after the finished product 1g that makes according to the embodiment of the invention 5 is dissolved in the ratio dissolving of 2000ml water, drink for livestock and poultry, use after 5 days, chicken group above-mentioned symptom disappears.
Experimental example 2
In August, 2006, Liaoning plant raises Hai Lanbai laying hen 4000 plumages, when raising to 220 ages in days, finds to produce shell egg, soft-shelled egg, egg production decline, and walking lamely appears in the chicken that has, and is diagnosed as vitamin D deficiency.Then after the finished product 1g that makes according to the embodiment of the invention 4 is dissolved in the ratio dissolving of 2000ml water, freely drink for poultry, use after 7 days, chicken group's above-mentioned symptom disappears.
Experimental example 3
In March, 2007, Heilungkiang plant raises Ai Weiyin meat kind chicken 1000 covers, when raising to 250 ages in days, finds a lot of chicken necks, subcutaneous tissue of chest's oedema, is purple or blue-green, and subcutaneous abdomen is accumulated a large amount of liquid; Find that simultaneously the rate of fertilization of kind of chicken and the incubation rate of kind egg reduce, and are diagnosed as vitamin e deficiency.Then after the finished product 1g that makes according to the embodiment of the invention 4 is dissolved in the ratio dissolving of 2000ml water, freely drink for poultry, use after 7 days, chicken group's above-mentioned symptom disappears.
Beta-cyclodextrin inclusion compound technology in the method for the invention has improved the water-soluble of vitamin A in the premixed feed, vitamin D, vitamin E greatly, livestock and poultry can be drunk for livestock and poultry by water way with the multivitamin premixed feed, make growth of animals or poultry even.This using method to premixed feed not only reduces the labour intensity in its feeding simultaneously, more solved livestock and poultry with multivitamin premixed feed and pellet because of granularity differs greatly can not mixing a difficult problem, solved thoroughly that livestock and poultry are easy to generate avitaminotic problem in the existing breeding technology, improved the price of deed and culture benefit.
Implement concrete mode
Following examples only are to instantiation of the present invention, are not structure of the present invention is done any pro forma restriction.Every foundation technical spirit of the present invention all still belongs in the scope of technical scheme of the present invention any simple modification, equivalent variations and modification that above embodiment did.
Embodiment 1
At room temperature predetermined amount of beta-cyclodextrin is joined in a certain amount of water, stir while adding, till beta-schardinger dextrin-no longer dissolves, behind solution left standstill, get the saturated solution that supernatant is made beta-schardinger dextrin-, stand-by.
Retinol1 0g is dissolved in the 100ml vegetable oil, the oil solution of this vitamin A is at room temperature slowly splashed in the beta-schardinger dextrin-saturated solution of 100ml with the speed of 200 of per minutes, at room temperature the speed with 600 rev/mins stirs while dripping, put cold behind the stirring 4h, put into 8 ℃ in refrigerator refrigeration 24h then, with the filtering with microporous membrane of 0.45um, with 60 ℃ of dryings of sediment 4 hours, dry thing is crossed 80 mesh sieves, get the Benexate Hydrochloride of vitamin A.
With vitamin D
33g is dissolved in the 3ml ethanol, with vitamin D
3Ethanolic solution slowly splash in the beta-schardinger dextrin-saturated solution of 30ml with the speed of 200 of per minutes, at room temperature the speed with 600 rev/mins stirs while dripping, put cold behind the stirring 4h, put into 8 ℃ of refrigeration of refrigerator 24h then, filtering with microporous membrane with 0.45um, with 60 ℃ of dryings of sediment 4 hours, dry thing is crossed 80 mesh sieves, vitamin D
3Benexate Hydrochloride.
Vitamin E 0.002g is dissolved in the ethanolic solution of 5ml, the ethanolic solution of the vitamin E speed with 200 of per minutes is slowly splashed in the beta-schardinger dextrin-saturated solution of 5ml, at room temperature the speed with 600 rev/mins stirs while dripping, put cold behind the stirring 4h, put into 8 ℃ in refrigerator refrigeration 24h then, with the filtering with microporous membrane of 0.45um, with 60 ℃ of dryings of sediment 4 hours, dry thing is crossed 80 mesh sieves, get the Benexate Hydrochloride of vitamin E.
Benexate Hydrochloride, vitamin D with the above-mentioned vitamin A of making
3Benexate Hydrochloride, the Benexate Hydrochloride and the Cobastab of vitamin E
13g, Cobastab
22g, Cobastab
63g, folic acid 0.05g, calcium pantothenate 1g mixing add oral glucose 250g mixing, promptly get pale yellow powder shape finished product.
Embodiment 2
At room temperature predetermined amount of beta-cyclodextrin is joined in a certain amount of water, stir while adding, till beta-schardinger dextrin-no longer dissolves, behind solution left standstill, get the saturated solution that supernatant is made beta-schardinger dextrin-, stand-by.
Vitamin A 40g is dissolved in the vegetable oil of 100ml, the oil solution of this vitamin A is at room temperature slowly splashed in the beta-schardinger dextrin-saturated solution of 100ml with the speed of 200 of per minutes, at room temperature the speed with 600 rev/mins stirs while dripping, put cold behind the stirring 4h, put into 8 ℃ in refrigerator refrigeration 24h then, with the filtering with microporous membrane of 0.45um, with 60 ℃ of dryings of sediment 4 hours, dry thing is crossed 80 mesh sieves, get the Benexate Hydrochloride of vitamin A.
With vitamin D
32g is dissolved in the 30ml ethanol, with vitamin D
3Ethanolic solution slowly splash in the beta-schardinger dextrin-saturated solution of 30ml with the speed of 200 of per minutes, at room temperature the speed with 600 rev/mins stirs while dripping, put cold behind the stirring 4h, put into 8 ℃ of refrigeration of refrigerator 24h then, filtering with microporous membrane with 0.45um, with 60 ℃ of dryings of sediment 4 hours, dry thing is crossed 80 mesh sieves, vitamin D
3Benexate Hydrochloride.
Vitamin E 0.005g is dissolved in the ethanolic solution of 5ml, the ethanolic solution of the vitamin E speed with 200 of per minutes is slowly splashed in the beta-schardinger dextrin-saturated solution of 5ml, at room temperature the speed with 600 rev/mins stirs while dripping, put cold behind the stirring 4h, put into 8 ℃ in refrigerator refrigeration 24h then, with the filtering with microporous membrane of 0.45um, with 60 ℃ of dryings of sediment 4 hours, dry thing is crossed 80 mesh sieves, get the Benexate Hydrochloride of vitamin E.
Benexate Hydrochloride, vitamin D with the above-mentioned vitamin A of making
3Benexate Hydrochloride, the Benexate Hydrochloride and the Cobastab of vitamin E
10.50g, Cobastab
21g, Cobastab
60.50g, folic acid 0.20g, calcium pantothenate 5 mixings, add oral glucose 350g mixing, promptly get pale yellow powder shape finished product.
Embodiment 3
At room temperature predetermined amount of beta-cyclodextrin is joined in a certain amount of water, stir while adding, till beta-schardinger dextrin-no longer dissolves, behind solution left standstill, get the saturated solution that supernatant is made beta-schardinger dextrin-, stand-by.
Dehydroretinol 0g is dissolved in the vegetable oil of 100ml, the oil solution of this vitamin A is at room temperature slowly splashed in the beta-schardinger dextrin-saturated solution of 100ml with the speed of 200 of per minutes, at room temperature the speed with 600 rev/mins stirs while dripping, put cold behind the stirring 4h, put into 8 ℃ in refrigerator refrigeration 24h then, with the filtering with microporous membrane of 0.45um, with 60 ℃ of dryings of sediment 4 hours, dry thing is crossed 80 mesh sieves, get the Benexate Hydrochloride of vitamin A.
With vitamin D
32.5g be dissolved in the 30ml ethanol, with vitamin D
3Ethanolic solution slowly splash in the beta-schardinger dextrin-saturated solution of 30ml with the speed of 200 of per minutes, at room temperature the speed with 600 rev/mins stirs while dripping, put cold behind the stirring 4h, put into 8 ℃ of refrigeration of refrigerator 24h then, filtering with microporous membrane with 0.45um, with 60 ℃ of dryings of sediment 4 hours, dry thing is crossed 80 mesh sieves, vitamin D
3Benexate Hydrochloride.
Vitamin E 0.004g is dissolved in the ethanolic solution of 5ml, the ethanolic solution of the vitamin E speed with 200 of per minutes is slowly splashed in the beta-schardinger dextrin-saturated solution of 5ml, at room temperature the speed with 600 rev/mins stirs while dripping, put cold behind the stirring 4h, put into 8 ℃ in refrigerator refrigeration 24h then, with the filtering with microporous membrane of 0.45um, with 60 ℃ of dryings of sediment 4 hours, dry thing is crossed 80 mesh sieves, get the Benexate Hydrochloride of vitamin E.
Benexate Hydrochloride, vitamin D with the above-mentioned vitamin A of making
3Benexate Hydrochloride, the Benexate Hydrochloride and the Cobastab of vitamin E
12g, Cobastab
25g, Cobastab
61g, folic acid 0.08g, calcium pantothenate 2g mixing add oral glucose 250g mixing, promptly get pale yellow powder shape finished product.
Embodiment 4
At room temperature predetermined amount of beta-cyclodextrin is joined in a certain amount of water, stir while adding, till beta-schardinger dextrin-no longer dissolves, behind solution left standstill, get the saturated solution that supernatant is made beta-schardinger dextrin-, stand-by.
3-Hydroxyretinol 0g is dissolved in the vegetable oil of 100ml, the oil solution of this vitamin A is at room temperature slowly splashed in the beta-schardinger dextrin-saturated solution of 100ml with the speed of 200 of per minutes, at room temperature the speed with 600 rev/mins stirs while dripping, put cold behind the stirring 4h, put into 8 ℃ in refrigerator refrigeration 24h then, with the filtering with microporous membrane of 0.45um, with 60 ℃ of dryings of sediment 4 hours, dry thing is crossed 80 mesh sieves, get the Benexate Hydrochloride of vitamin A.
With vitamin D
32.8g be dissolved in the 3ml ethanol, with vitamin D
3Ethanolic solution slowly splash in the beta-schardinger dextrin-saturated solution of 30ml with the speed of 200 of per minutes, while dripping at room temperature with 600 rev/mins of stirrings, put cold behind the stirring 4h, put into 8 ℃ of refrigeration of refrigerator 24h then, filtering with microporous membrane with 0.45um, with 60 ℃ of dryings of sediment 4 hours, dry thing is crossed 80 mesh sieves, vitamin D
3Benexate Hydrochloride.
Vitamin E 0.003g is dissolved in the ethanolic solution of 5ml, the ethanolic solution of the vitamin E speed with 200 of per minutes is slowly splashed in the beta-schardinger dextrin-saturated solution of 5ml, at room temperature the speed with 600 rev/mins stirs while dripping, put cold behind the stirring 4h, put into 8 ℃ in refrigerator refrigeration 24h then, with the filtering with microporous membrane of 0.45um, with 60 ℃ of dryings of sediment 4 hours, dry thing is crossed 80 mesh sieves, get the Benexate Hydrochloride of vitamin E.
Benexate Hydrochloride, vitamin D with the above-mentioned vitamin A of making
3Benexate Hydrochloride, the Benexate Hydrochloride and the Cobastab of vitamin E
12.5g, Cobastab
24g, Cobastab
62.5g, folic acid 0.15g, calcium pantothenate 4g mixing, add oral glucose 300g mixing, promptly get pale yellow powder shape finished product.
Embodiment 5
At room temperature predetermined amount of beta-cyclodextrin is joined in a certain amount of water, stir while adding, till beta-schardinger dextrin-no longer dissolves, behind solution left standstill, get the saturated solution that supernatant is made beta-schardinger dextrin-, stand-by.
Retinol1 5g is dissolved in the vegetable oil of 100ml, the oil solution of this vitamin A is at room temperature slowly splashed in the beta-schardinger dextrin-saturated solution of 100ml with the speed of 200 of per minutes, at room temperature the speed with 600 rev/mins stirs while dripping, put cold behind the stirring 4h, put into 8 ℃ in refrigerator refrigeration 24h then, with the filtering with microporous membrane of 0.45um, with 60 ℃ of dryings of sediment 4 hours, dry thing is crossed 80 mesh sieves, get the Benexate Hydrochloride of vitamin A.
With vitamin D
32.2g be dissolved in the 30ml ethanol, with vitamin D
3Ethanolic solution slowly splash in the beta-schardinger dextrin-saturated solution of 30ml with the speed of 200 of per minutes, at room temperature the speed with 600 rev/mins stirs while dripping, put cold behind the stirring 4h, put into 8 ℃ of refrigeration of refrigerator 24h then, filtering with microporous membrane with 0.45um, with 60 ℃ of dryings of sediment 4 hours, dry thing is crossed 80 mesh sieves, vitamin D
3Benexate Hydrochloride.
Vitamin E 0.003g is dissolved in the ethanolic solution of 5ml, the ethanolic solution of the vitamin E speed with 200 of per minutes is slowly splashed in the beta-schardinger dextrin-saturated solution of 5ml, at room temperature the speed with 600 rev/mins stirs while dripping, put cold behind the stirring 4h, put into 8 ℃ in refrigerator refrigeration 24h then, with the filtering with microporous membrane of 0.45um, with 60 ℃ of dryings of sediment 4 hours, dry thing is crossed 80 mesh sieves, get the Benexate Hydrochloride of vitamin E.
Benexate Hydrochloride, vitamin D with the above-mentioned vitamin A of making
3Benexate Hydrochloride, the Benexate Hydrochloride and the Cobastab of vitamin E
11.5g, Cobastab
23g, Cobastab
62g, folic acid 0.12g, calcium pantothenate 3g mixing add oral glucose 280g mixing, promptly get pale yellow powder shape finished product.
Embodiment 6
At room temperature predetermined amount of beta-cyclodextrin is joined in a certain amount of water, stir while adding, till beta-schardinger dextrin-no longer dissolves, behind solution left standstill, get the saturated solution that supernatant is made beta-schardinger dextrin-, stand-by.
Dehydroretinol 5g is dissolved in the vegetable oil of 100ml, the oil solution of this vitamin A is at room temperature slowly splashed in the beta-schardinger dextrin-saturated solution of 100ml with the speed of 200 of per minutes, at room temperature the speed with 600 rev/mins stirs while dripping, put cold behind the stirring 4h, put into 8 ℃ in refrigerator refrigeration 24h then, with the filtering with microporous membrane of 0.45um, with 60 ℃ of dryings of sediment 4 hours, dry thing is crossed 80 mesh sieves, get the Benexate Hydrochloride of vitamin A.
With vitamin D
33g is dissolved in the 30ml ethanol, with vitamin D
3Ethanolic solution slowly splash in the beta-schardinger dextrin-saturated solution of 30ml with the speed of 200 of per minutes, at room temperature the speed with 600 rev/mins stirs while dripping, put cold behind the stirring 4h, put into 8 ℃ of refrigeration of refrigerator 24h then, filtering with microporous membrane with 0.45um, with 60 ℃ of dryings of sediment 4 hours, dry thing is crossed 80 mesh sieves, vitamin D
3Benexate Hydrochloride.
Vitamin E 0.003g is dissolved in the ethanolic solution of 5ml, the ethanolic solution of the vitamin E speed with 200 of per minutes is slowly splashed in the beta-schardinger dextrin-saturated solution of 5ml, at room temperature the speed with 600 rev/mins stirs while dripping, stir put behind the 4h cold put cold, put into 8 ℃ in refrigerator refrigeration 24h then, with the filtering with microporous membrane of 0.45um, with 60 ℃ of dryings of sediment 4 hours, dry thing is crossed 80 mesh sieves, get the Benexate Hydrochloride of vitamin E.
With above-mentioned vitamin A Benexate Hydrochloride, the vitamin D of making
3Benexate Hydrochloride, vitamin E Benexate Hydrochloride and Cobastab
12.8g, Cobastab
22g, Cobastab
62.2g, folic acid 0.1g, calcium pantothenate 2g mixing, add oral glucose 300g mixing, promptly get pale yellow powder shape finished product.
Claims (4)
1. one kind contains multivitamin livestock and poultry and uses the premixed feed preparation method, it is characterized in that described preparation method is:
A. at room temperature predetermined amount of beta-cyclodextrin is joined in a certain amount of water, stir while adding, till beta-schardinger dextrin-no longer dissolved, behind solution left standstill, getting supernatant, to make the saturated solution of beta-schardinger dextrin-stand-by;
B. 0 part～40 parts of retinol1s are dissolved in 100 parts the vegetable oil, make the oil solution of vitamin A; The oil solution of said vitamin A is at room temperature slowly splashed in 100 parts of above-mentioned beta-schardinger dextrin-saturated solutions made from the speed of 200 of per minutes, stir 4h while dripping with 600 rev/mins, put cold back and refrigerate 24h down at 8 ℃, filtering with microporous membrane with 0.45um, with sediment 60 ℃ of dryings 4 hours, dry thing is crossed 80 mesh sieves, gets the vitamin A Benexate Hydrochloride;
C. with vitamin D
32～3 parts are dissolved in 30 part 95% the ethanolic solution, make vitamin D
3Ethanolic solution; With said vitamin D
3Ethanolic solution at room temperature slowly splash in 30 parts of above-mentioned 3-cyclodextrin saturated solutions made from the speed of 200 of per minutes, stir 4h while dripping with 600 rev/mins, put cold back and refrigerate 24h down at 8 ℃, filtering with microporous membrane with 0.45um, with 60 ℃ of dryings of sediment 4 hours, dry thing is crossed 80 mesh sieves, get vitamin D
3Benexate Hydrochloride;
D. 0.002～0.005 part of vitamin E is dissolved in 5 part 95% the ethanolic solution, makes the ethanolic solution of vitamin E; The ethanolic solution of vitamin E is at room temperature slowly splashed in 5 parts of above-mentioned beta-schardinger dextrin-saturated solutions made from the speed of 200 of per minutes, stir 4h while dripping with 600 rev/mins, put and put into refrigerator after cold at 8 ℃ of refrigeration 24h down, filtering with microporous membrane with 0.45um, with 60 ℃ of dryings of sediment 4 hours, dry thing is crossed 80 mesh sieves, get the vitamin E Benexate Hydrochloride;
E. with above-mentioned vitamin A Benexate Hydrochloride, the vitamin D of making respectively
3Benexate Hydrochloride, vitamin E Benexate Hydrochloride and Cobastab
10.5 part～3 parts, Cobastab
21 part～5 parts, Cobastab
60.5 part～3 parts, 0.05～0.2 part in folic acid, 1 part～5 parts of calcium pantothenates and meet 200 parts～350 parts mixings of glucose for oral use of Chinese veterinary drug allusion quotation version standard in 2005, get product.
2. according to claim 1ly a kind ofly contain multivitamin livestock and poultry and use the premixed feed preparation method, the preferred values that it is characterized in that described vitamin A is 25 parts, vitamin D
3Preferred values be 3 parts, the preferred values of vitamin E is 0.003 part, Cobastab
1Preferred values be 1 part, Cobastab
2Preferred values be 3 parts, Cobastab
6Preferred values be 2 parts, the preferred values of folic acid is 0.1 part, the preferred values of calcium pantothenate is 3 parts, the preferred values of glucose is 300 parts.
3. according to claim 1ly a kind ofly contain multivitamin livestock and poultry and use the premixed feed preparation method, it is characterized in that described various vitamin, folic acid, calcium pantothenate are feed grade.
4. one kind contains multivitamin livestock and poultry according to the described method made of claim 1 a kind of and uses premixed feed, it is characterized in that described premixed feed finished product is flaxen powder.
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| CN2007100597525A CN101301026B (en) | 2007-09-21 | 2007-09-21 | Premixing feed for livestock and poultry containing multivitamins and method for preparing the same |
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| CN102048031A (en) * | 2010-12-27 | 2011-05-11 | 中牧实业股份有限公司 | Compound nutrient for poultry drinking water |
| CN114128806A (en) * | 2021-12-13 | 2022-03-04 | 河南正本清源科技发展股份有限公司 | Antibiotic-free and zinc-free piglet concentrated feed and preparation method thereof |
| CN115104682A (en) * | 2022-05-26 | 2022-09-27 | 开封金万德福生物科技有限公司 | Composite vitamin premix feed for improving egg quality, production process and use method |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1213667C (en) * | 2000-09-05 | 2005-08-10 | 巴斯夫中国有限公司 | High-concentration composite nutrient additive for phosphorus-saving type environment-protecting feed |
| CN1429595A (en) * | 2001-12-30 | 2003-07-16 | 黄文武 | Domestic fowl auxin containing composite vitamins |
| CN100527985C (en) * | 2004-07-19 | 2009-08-19 | 北京科润维德生物技术有限责任公司 | Premixed forage for young beef or young white ox, and its usage |
-
2007
- 2007-09-21 CN CN2007100597525A patent/CN101301026B/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102048031A (en) * | 2010-12-27 | 2011-05-11 | 中牧实业股份有限公司 | Compound nutrient for poultry drinking water |
| CN102048031B (en) * | 2010-12-27 | 2012-12-26 | 中牧实业股份有限公司 | Compound nutrient for poultry drinking water |
| CN114128806A (en) * | 2021-12-13 | 2022-03-04 | 河南正本清源科技发展股份有限公司 | Antibiotic-free and zinc-free piglet concentrated feed and preparation method thereof |
| CN115104682A (en) * | 2022-05-26 | 2022-09-27 | 开封金万德福生物科技有限公司 | Composite vitamin premix feed for improving egg quality, production process and use method |
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| CN101301026B (en) | 2011-12-07 |
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