CN101284078A - Nicandra physalodes (simple recipe) decocted in water for curing cardiovascular disease - Google Patents
Nicandra physalodes (simple recipe) decocted in water for curing cardiovascular disease Download PDFInfo
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- CN101284078A CN101284078A CNA200710055519XA CN200710055519A CN101284078A CN 101284078 A CN101284078 A CN 101284078A CN A200710055519X A CNA200710055519X A CN A200710055519XA CN 200710055519 A CN200710055519 A CN 200710055519A CN 101284078 A CN101284078 A CN 101284078A
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Abstract
The invention relates to a discovery of single prescription of apple-of-peru (entire plant: root, seed and flower) in treating cardiovascular disease, particularly in the preparation of cardiovascular disease medicine. The apple-of-peru is only used in edible gel and outdated pharmaceutical range in the past. For example, the apple-of-peru has heat and toxic material clearing away effect (used for treating edema and furuncle); and can be used for treating rabies, psychosis, epilepsy, rheumatalgia, sore and furuncle, common cold, etc. A new discovery is made in 2004 that the apple-of-peru has good curative effect on chronic nephropathy. Our clinical observation indicates that the apple-of-peru can be used for obviously treating patients of nephropathy accompanied with cardiovascular disease. Thus, one to twenty patients having cardiovascular disease without nephropathy are observed. It is summarized that the apple-of-peru (single prescription) medicinal decoction has good curative effect on cardiovascular disease, especially hypertension and coronary heart disease.
Description
Technical field:
The present invention relates to the purposes of Herba Nicandrae Physaloidis (herb: root, son, flower) when being used as medicine, relate in particular to the application of Herba Nicandrae Physaloidis (folk prescription) in preparation treatment cardiovascular disease medicine.
Background technology:
Fructus seu semen nicandrae physaloidis originates in Peru, is the seed or the fruit of dicotyledon medicine plant of Solanaceae Herba Nicandrae Physaloidis.It is many in plantation of provinces such as south or natural propagation to introduce the China back, just begins in the last few years to plant in the north.
All the time, people are food glue to the understanding one of its purposes, do bean jelly or fruit jelly etc.; The 2nd, medicinal, controlling abdominal distention, stomachache, diarrhoea, rheumatic arthritis, wind and cold according to " Guizhou medical herbs " record coughs and gargles, rabies, psychosis, epilepsy, rheumatalgia, furuncle, flu are controlled in " Yunnan Chinese herbal medicine " record, and eruptive disease etc. is controlled in the cough-relieving of " the Guangxi medicine is planted register " record energy.
Process is to the medicinal observation of the Herba Nicandrae Physaloidis of cultivated in north, and Herba Nicandrae Physaloidis (folk prescription) has curative effect preferably to the treatment cardiovascular disease.
Summary of the invention:
The present invention mainly is that Herba Nicandrae Physaloidis (folk prescription) is taken after with an amount of decocting and can be treated cardiovascular disease.
Clinical research is summed up
The Herba Nicandrae Physaloidis decoction is to be applied to treat chronic nephritis, the medicine of chronic renal failure originally.Finding but in application that a lot of nephropathy have had with patient's cardiovascular disease when controlling nephropathy of cardiovascular disease is clearly better.Lowered according to the blood pressure of height under not, phenomenon uncomfortable in chest, that breathe hard has alleviated, the angina pectoris attacks frequency has obviously reduced, upward downstairs health energetically, the people also spirit many.In this year, we observe the cardiovascular patient's that do not have nephropathy medication, be listed as twenties sick row from a disease, we sum up Herba Nicandrae Physaloidis (folk prescription) mixture has curative effect preferably to the treatment cardiovascular disease, particularly evident in efficacy to treatment hypertension, coronary heart disease.
Case 1, Li Jin: the woman, 72 years old, coronary heart disease, hypertension 3 years often had pareordia or left side shoulder, back pain, the nervous sometimes headache frequent micturition at midnight of breathing hard.Patient's obesity, Blushing, blood pressure 156/70mmhg, electrocardio: bradycardia, left axis deviation.Creatinine 110 (height), urine protein (±).
Herba Nicandrae Physaloidis (folk prescription) is decocted in water for oral dose two courses of treatment (60 days), and angina pectoris disappears substantially, blood pressure 130-140/75mmhg, and nocturnal urine output reduces 1/3, creatinine 0 (normally), urine protein (-).
Case 2, Zhu Xianglan, the woman, 68 years old, coronary heart disease, hypertension 5 years, throughout the year oral blood pressure lowering and coronary dilating medicine, summer, subjective symptoms did not have, once having an attack of one's old illness to winter, cardiopalmus, breathe hard, uncomfortable in chest increasing the weight of, hypertension 160/98mmhg, heart rate quickens, myocardial strain.
Herba Nicandrae Physaloidis (folk prescription) is decocted in water for oral dose two courses of treatment (60 days), and this winter, subjective symptoms obviously alleviated, and atrial fibrillation only shows effect once, and precordialgia disappears substantially, and blood pressure maintains 135/90mmhg, also can do a little slight housework.
Case 3, Zhao Gang, man, 58 years old, coronary heart disease, angina pectoris half a year.Once hospitalization, tired now or excited after upper abdomen and left shoulder the compression sense is arranged, nervous, outbreak in the recent period is frequent, patient has fear.Blood pressure 130/88mmhg, electrocardiogram are roughly normal.
Herba Nicandrae Physaloidis (folk prescription) decocting oral one and half courses of treatment (45 days), above-mentioned symptom disappears, can operate as normal.
Case 4, Wang Zhenli, the man, 66 years old, coronary heart disease, hypertension, hyperlipidemia 6 years, patient has the paroxysmal precordialgia, especially heavy meal or show effect at night more, headache, insomnia.Triglyceride 4.5, blood pressure 182/110mmhg, blood ester, high density cholesterol 0.7, low density cholesterol 4.0.
Herba Nicandrae Physaloidis (folk prescription) is decocted in water for oral dose two courses of treatment (60 days), and angina pectoris attacks is not obvious, and the property a crossed shirtfront or back backache are only arranged, and number of times is few to be taken for two courses of treatment with depressor commonly used is collaborative, blood pressure is reduced to 154/92mmhg, triglyceride 2.6, high density cholesterol 1.5, low density cholesterol 2.6.
Case 5, Zheng Peirong, the woman, 70 years old, coronary heart disease, hypertension, hyperlipidemia 7 years, patient often has a sleepless night, headache sometimes, it is also unstable that conventional depressor is taken blood pressure, tired slightly or angry with regard to the vexed pressure in front, paroxysmal pain, pained recent attack times increase and the time longer.Blood pressure: 190/120mmhg, electrocardio, myocardial strain, left ventricular hypertrophy, having family property frequent premature beat.
Herba Nicandrae Physaloidis (folk prescription) is decocted in water for oral dose two courses of treatment (60 days), and angina pectoris only is to shorten a property crossed and time, and no premature beat occurs, and sleep quality has improvement, blood pressure 150-160/94-100mmhg,
Case 6, Zhang Qian, the woman, 51 years old, chronic nephritis 8 years was with hypertension, coronary heart disease.Patient's menopause syndrome is obvious, cardiopalmus, hyperhidrosis, insomnia, often precordialgia is arranged.Eye face edema and ankle finger pressure concavity edema.Urine examination: specific gravity of urine 1.009, albumen ++, erythrocyte 4-6/, serum creatinine 112, blood pressure 168/100mmhg, electrocardiogram: left ventricular hypertrophy, idol has premature beat, and exercise testing brings out angina pectoris.
Herba Nicandrae Physaloidis was decocted in water for oral dose after two courses of treatment (60 days), urine protein (±), specific gravity of urine 1.040, blood pressure 160/90mmhg, no angina pectoris outbreak.
Case 7, Xiao Juyan, woman, 66 years old, coronary heart disease, angina pectoris 2 years.Go home after the hospitalization improvement from April, 06, front, the sample of acupuncture behind pain are often arranged, dizzy, nauseating.Blood pressure: 170/80mmhg, electrocardio: tachycardia, myocardial ischemia.
Take course of treatment of Herba Nicandrae Physaloidis decoction, the angina pectoris number of times obviously reduces, and is dizzy, feeling sick disappears, and can do housework blood pressure: 150/80mmhg.
Case 8, Li Fenglan, woman, 58 years old, hypertension, coronary heart disease 7 years.Patient is recently in heavy meal, night or early morning, and pareordia has the vexed sense of contracting of pressure, breathes hard, and needs clothes coronary dilating prescription can alleviate headache, tinnitus, insomnia.Blood pressure: 180/120mmhg, electrocardiogram: arrhythmia, myocardial strain, left ventricular hypertrophy,
Herba Nicandrae Physaloidis was decocted in water for oral dose after two courses of treatment (60 days), no angina pectoris outbreak, and tinnitus disappears, and sleep at night is good, and blood pressure maintains 160-140/100-90mmhg, and headache disappears.
Case 9, Zhang Qian, man, 62 years old, coronary heart disease, hypertension, hyperlipidemia 3 years.Patient is tired slightly or excited just to palpitate quickly, the front constriction, feel suffocated, headache sometimes.Blood pressure 170/110mmhg, electrocardio: tachycardia, accidental chamber early, left ventricular hypertrophy.Blood fat: triglyceride 2.6, high density cholesterol 0.7, low density cholesterol 3.8.
Herba Nicandrae Physaloidis was decocted in water for oral dose after two courses of treatment (60 days), and patient's angina pectoris does not have obvious outbreak, and electrocardio does not have other variations except that left ventricular hypertrophy, high density cholesterol 1.5.
Case 10, Wang Ruihua, man, 71 years old, coronary heart disease, hypertension 9 years.Patient's obesity, often have shirtfront back pain, soreness of waist pain, nocturia frequently, ankle has slight edema.Blood pressure 182/106mmhg, electrocardio: myocardial strain, left ventricular hypertrophy, blood fat: triglyceride 1.7, high density cholesterol 2.0, low density cholesterol 4.0, creatinine 109, blood urea nitrogen 6.5, urine protein (+).
Herba Nicandrae Physaloidis was decocted in water for oral dose after two courses of treatment (60 days), and patient's angina pectoris does not have obvious minimizing, only is accidental.Blood pressure 166/96mmhg, creatinine 96, blood urea nitrogen 4.0, urine protein (-).
Technical scheme:
1, Herba Nicandrae Physaloidis is boiled by 1: 15 (water) decocting, extracting solution packing (100ml) promptly is mixture;
2, Herba Nicandrae Physaloidis is extracted into injection;
3, Herba Nicandrae Physaloidis is prepared into capsule (granule);
4, Herba Nicandrae Physaloidis is prepared into tablet.
Effect and implementation method:
The present invention controls cardiovascular disease.Symptoms such as hypertension, hyperlipidemia, coronary heart disease can significantly take a turn for the better.And expense is low, and side effect is little, and quality of life obviously improves, and the social benefit prospect is considerable.Actively carry out pharmacy part, pharmacodynamics, anxious poison and long term toxicity test report, for preliminary preparation is carried out in clinical use.
Claims (3)
1, Herba Nicandrae Physaloidis (folk prescription) is decocted in water for oral dose and controls cardiovascular disease.Comprising: hypertension, hyperlipidemia, coronary heart disease etc.
2, the use of Herba Nicandrae Physaloidis (folk prescription) in the Chinese medicine preparation of treatment cardiovascular disease is characterized in that the Herba Nicandrae Physaloidis preparation is a single preparations of ephedrine.
3, Herba Nicandrae Physaloidis (folk prescription) is included in the Chinese medicine preparation of treatment cardiovascular disease is injection, mixture, granule, tablet.
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CNA200710055519XA CN101284078A (en) | 2007-04-12 | 2007-04-12 | Nicandra physalodes (simple recipe) decocted in water for curing cardiovascular disease |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105725188A (en) * | 2016-02-04 | 2016-07-06 | 娄向光 | Plant nicandra physaloides which is planted in weakly-alkaline soil and can remarkably enhance human immunity when decocted with water |
CN109288812A (en) * | 2018-11-14 | 2019-02-01 | 浙江海洋大学 | A kind of preparation method of false acid pulp carbohydrate gum microballoon |
-
2007
- 2007-04-12 CN CNA200710055519XA patent/CN101284078A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105725188A (en) * | 2016-02-04 | 2016-07-06 | 娄向光 | Plant nicandra physaloides which is planted in weakly-alkaline soil and can remarkably enhance human immunity when decocted with water |
CN109288812A (en) * | 2018-11-14 | 2019-02-01 | 浙江海洋大学 | A kind of preparation method of false acid pulp carbohydrate gum microballoon |
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Open date: 20081015 |