CN106540142A

CN106540142A - It is a kind of to prevent cardiopathic compound preparation and preparation method thereof

Info

Publication number: CN106540142A
Application number: CN201710040441.8A
Authority: CN
Inventors: 季益林
Original assignee: Individual
Current assignee: Individual
Priority date: 2017-01-20
Filing date: 2017-01-20
Publication date: 2017-03-29

Abstract

The invention discloses a kind of prevent cardiopathic compound preparation and preparation method thereof, the compound preparation is made up of the following raw material according to quality：5 10 grams of radix bupleuri, 5 10 grams of costus root, green Pericarpium Citri Reticulatae are each 5 10 grams, 10 20 grams of giant knotweed, 5 10 grams of rhubarb, 5 15 grams of the flower bud of lily magnolia, 10 20 grams of cape jasmine, 10 20 grams of raw hawthorn, 10 20 grams of Sculellaria barbata, fry 5 10 grams of Fructus Aurantii, 10 20 grams of the tuber of dwarf lilyturf, 15 25 grams of the dried rhizome of rehmannia, 10 20 grams of calcined gypsum, 5 15 grams of lily, 10 20 grams of the wind-weed, batch 10 20 grams of leaf, 5 15 grams of the root of large-flowered skullcap, 10 20 grams of cassia twig, 5 15 grams of rattletop, 15 25 grams of the membrane of a chicken's gizzard, 8 13 grams of the seed of cowherb, 5 10 grams of radix cyathulae, 5 15 grams of caulis lonicerae, 5 10 grams of golden cypress, 5 10 grams of Semen Coicis Semen Coicis.Medicine of the present invention can with it is promoting blood circulation and removing blood stasis for coronary atherosclerosis focus, remove obstruction in channels to relieve pain the effect of, improve coronary insufficiency, myocardial anoxia, uncomfortable in chest, cardio palmus shape, clinically prevent coronary disease and angina pectoris bradycardia etc., curative effect is superior.

Description

It is a kind of to prevent cardiopathic compound preparation and preparation method thereof

Technical field

The present invention relates to technical field of pharmaceuticals, specifically a kind of to prevent cardiopathic compound preparation and preparation method thereof.

Background technology

Coronary atherosclerotic heart disease：It is that the heart disease of myocardial ischemia generation is caused due to coronary artery stenosis, Which is referred to as coronary heart disease.The coronary atherosclerotic heart disease cause of disease：(1) coronary insufficiency：Coronary artery is athero- hard Change patch, coronarospasm and secondary arthritis（Such as thrombosis, patch internal haemorrhage etc.）Cause artery official jargon narrow, the heart Flesh blood supply insufficiency.(2) MCO increases severely, and such as overworked, excited, blood pressure rises sharply, and the reason such as tachycardia, is the heart Flesh load increases, and blood supply coronarius accordingly can not increase therewith, causes myocardial ischemia.

The main clinical manifestation of coronary heart disease：(1) angina pectoris：Angina pectoris is divided into pain degree according to the reason for causing：1. it is steady Sizing angina pectoris 2. unstable angina pectoris 3. variant angina pectoris.(2) myocardial infarction：Coronary artery continuation blood supply interruption is drawn The regional myocardial ischemia's property necrosis for rising, referred to as myocardial infarction.Clinic has a violent and lasting retrosternal pain, leukocytosis, Serum myocardial enzyme level is raised and ECG Change, is the serious and common type of coronary heart disease.The biochemical change of myocardial infarction：By Glycolysis when myocardial anoxia is strengthened, and after 30 minutes, in cardiac muscle cell, glycogen is reduced or disappeared myocardial ischemia；Myocardium cell necrosis Afterwards, the glutamic-oxaloacetic transaminase in cardiac muscle cell, glutamic-pyruvic transaminase, cretinephosphokinase and lactic acid take off Hydrogen enzyme is released into blood through cell membrane, causes the concentration of these enzymes in serum to raise.The complication of myocardial infarction：1. heart failure is 2. Cardiogenic shock 3. arrhythmia cordis 4. aneurysm 5. lateral thrombus forms 6. cardiac rupture 7. acute pericarditis.(3) cardiac muscle fibre Change：Due to coronary artery stenosis, cardiac muscle fibre is long-term, repetitious hypoxic-ischemic, makes cardiac muscle that atrophy, denaturation and interstitial to occur Proliferation of fibrous tissue, can cause extensive myocardial fibrosis.The last disease for gradually developing into heart failure.(4) coronary Sudden death：40～50 years old patient is more common in coronary sudden death, and the male sex is more compared with women.Patient can faint suddenly, and tic of limbs is little Fecal incontinence, or burst expiratory dyspnea, spit out white foams, rapid to go into a coma.I.e. death after paresthesia epilepsy, or death in one to a few hours. What is had can be dead in sleeping at night.Some cases coronary atherosclerosis is relatively light or dies suddenly without atherosclerotic, can Can be due to coronarospasm or coronary embolism etc..

Patients with coronary artery disease easily produces drug resistance to Western medicine, and the recurrence rate performed the operation is higher or even clinically dead, therefore west Medicine lacks effectively radical cure method to coronary heart disease.Cause most of patient for treatment to lose the confidence, and the traditional Chinese medical science then set about from the cause of disease, The method for taking diagnosis and treatment, need get hold of medication time according to the different card type performance of patient, and comprehensive analysis is obtained this Bright medicine.

The content of the invention

It is an object of the invention to provide a kind of therapeutic effect is good, can prevent cardiopathic compound preparation and its preparation side Method, to solve the problems, such as to propose in above-mentioned background technology.

For achieving the above object, the present invention provides following technical scheme：

It is a kind of to prevent cardiopathic compound preparation, it is made up of the following raw material according to quality：5-10 gram of radix bupleuri, costus root 5-10 Gram, green Pericarpium Citri Reticulatae is each 5-10 gram, 10-20 gram of giant knotweed, 5-10 gram of rhubarb, 5-15 gram of the flower bud of lily magnolia, 10-20 gram of cape jasmine, raw hawthorn 10-20 Gram, 10-20 gram of Sculellaria barbata fries 5-10 gram of Fructus Aurantii, 10-20 gram of the tuber of dwarf lilyturf, 15-25 gram of the dried rhizome of rehmannia, 10-20 gram of calcined gypsum, lily 5-15 Gram, 10-20 gram of the wind-weed is processed batch 10-20 gram of leaf, 5-15 gram of the root of large-flowered skullcap, 10-20 gram of cassia twig, 5-15 gram of rattletop, the membrane of a chicken's gizzard 15-25 Gram, 8-13 gram of the seed of cowherb, 5-10 gram of radix cyathulae, 5-15 gram of caulis lonicerae, 5-10 gram of golden cypress, 5-10 gram of Semen Coicis Semen Coicis.

As further scheme of the invention：It is described to prevent cardiopathic compound preparation, by the following raw material according to quality Composition：7-9 gram of radix bupleuri, 7-9 gram of costus root, green Pericarpium Citri Reticulatae are each 7-9 gram, 12-16 gram of giant knotweed, 7-9 gram of rhubarb, 7-11 gram of the flower bud of lily magnolia, 12-16 gram of cape jasmine, raw hawthorn 12-16 gram, 12-16 gram of Sculellaria barbata, 7-9 gram of Fructus Aurantii of stir-fry, 12-16 gram of the tuber of dwarf lilyturf, 16-22 gram of the dried rhizome of rehmannia, 12-16 gram of calcined gypsum, 7-11 gram of lily, 12-16 gram of the wind-weed, batch 12-16 gram of leaf, 7-11 gram of the root of large-flowered skullcap, 12-16 gram of cassia twig, liter Numb 7-11 gram, 16-22 gram of the membrane of a chicken's gizzard, 9-12 gram of the seed of cowherb, 7-9 gram of radix cyathulae, 7-11 gram of caulis lonicerae, 7-9 gram of golden cypress, the raw heart of a lotus seed 7-9 gram of the seed of jog's tears.

As further scheme of the invention：It is described to prevent cardiopathic compound preparation, by the following raw material according to quality Composition：8 grams of radix bupleuri, 8 grams of costus root, green Pericarpium Citri Reticulatae are each 8 grams, 14 grams of giant knotweed, 8 grams of rhubarb, 9 grams of the flower bud of lily magnolia, 14 grams of cape jasmine, raw hawthorn 14 grams, 14 grams of Sculellaria barbata fries 8 grams of Fructus Aurantii, 14 grams of the tuber of dwarf lilyturf, 19 grams of the dried rhizome of rehmannia, 14 grams of calcined gypsum, 9 grams of lily, 14 grams of the wind-weed, batch handle 14 grams of leaf, 9 grams of the root of large-flowered skullcap, 14 grams of cassia twig, 9 grams of rattletop, 19 grams of the membrane of a chicken's gizzard, 11 grams of the seed of cowherb, 8 grams of radix cyathulae, 9 grams of caulis lonicerae, 8 grams of golden cypress, 8 grams of Semen Coicis Semen Coicis.

Another object of the present invention is to provide a kind of preparation method of the cardiopathic compound preparation of prevention, comprises the following steps：

1）Calcined gypsum is packaged with gauze bag, is put in full-automatic medicine boiling packaging machine cylinder, is put into suitable quantity of water, cross the water surface and forge stone Cream 1.8-2.5cm, decocts 25-35min standby；

2）Again by radix bupleuri, costus root, green Pericarpium Citri Reticulatae, giant knotweed, the flower bud of lily magnolia, cape jasmine, raw hawthorn, Sculellaria barbata, fry Fructus Aurantii, the tuber of dwarf lilyturf, the dried rhizome of rehmannia, hundred Conjunction, the wind-weed, batch leaf, the root of large-flowered skullcap, cassia twig, rattletop, the membrane of a chicken's gizzard, the seed of cowherb, radix cyathulae, caulis lonicerae, golden cypress, Semen Coicis Semen Coicis yarn Cloth bag is put into above-mentioned steps 1 after packaging）Full-automatic medicine boiling packaging machine cylinder in, water level flooded above-mentioned raw materials 1.5-3cm； Then intense fire is boiled, then is cooked by slow fire 20-60min；Again rhubarb gauze bag is packaged and is put in cylinder, decoct 3-10 minutes, Filtrate is filtered to take, packaging bag is poured into and is obtained final product compound preparation.

As further scheme of the invention：Step 2）In, radix bupleuri, costus root, green Pericarpium Citri Reticulatae, giant knotweed, the flower bud of lily magnolia, cape jasmine, life Hawthorn, Sculellaria barbata, fry Fructus Aurantii, the tuber of dwarf lilyturf, the dried rhizome of rehmannia, lily, the wind-weed, batch leaf, the root of large-flowered skullcap, cassia twig, rattletop, the membrane of a chicken's gizzard, the seed of cowherb, Radix cyathulae, caulis lonicerae, golden cypress, Semen Coicis Semen Coicis soak 20-60min before addition.

As further scheme of the invention：Radix bupleuri, costus root, green Pericarpium Citri Reticulatae, giant knotweed, the flower bud of lily magnolia, Sculellaria barbata, stir-fry Fructus Aurantii, wheat Winter, the dried rhizome of rehmannia, lily, the wind-weed, batch leaf, the root of large-flowered skullcap, cassia twig, rattletop, the membrane of a chicken's gizzard, the seed of cowherb, radix cyathulae, caulis lonicerae, golden cypress are existed Immersion 20-30min before adding；Cape jasmine, raw hawthorn, Semen Coicis Semen Coicis soak 60min before addition.

As further scheme of the invention：Step 1）In, make the water surface cross calcined gypsum 2cm.

As further scheme of the invention：Step 2）In, water level flooded above-mentioned raw materials 2cm.

As further scheme of the invention：Step 2）In, the mode of filtration takes juice using marc.

As further scheme of the invention：Repeat step 2）Decoction, filter process 1-2 time.

Radix bupleuri 1. nature and flavor in the present invention：Taste is pungent, bitter, cold nature 2. return through：Return liver courage lung channel 3. effect：In inducing sweat, dredge Liver solution is strongly fragrant, yang invigorating, preventing malaria of bringing down a fever.

Costus root 1. nature and flavor：Taste is pungent, bitter, 2. return through warm in nature：Taste liver large intestine channel 3. effect：Middle benefit gas promoting qi circulation and relieving pain, fragrance Row dissipates.

Rascal 1. nature and flavor：Bitter, pungent, 2. return through warm in nature：Return liver courage stomach 3. effect：Soothing the liver relieving stagnant Qi, the productization that disappears are stagnant.

Dried orange peel 1. nature and flavor：Bitter, pungent, 2. return through warm in nature：Return lung the spleen channel 3. effect：Regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm.

Giant knotweed 1. nature and flavor：Mildly bitter flavor, cold nature 2. return through：Return liver courage lung channel 3. effect：Removing dampness through diuresis and removing jaundice, it is clearing heat and detoxicating, dissipate Stasis of blood pain relieving, it is relieving cough and reducing sputum.

Rhubarb 1. nature and flavor：Hardship, 2. return through cold in nature：Returns spleen stomach and liver large intestine channel 3. effect：Attack stagnant, clearing away damp-heat, purging intense heat are cool Blood, dissolving stasis, removing toxic substances.

The flower bud of lily magnolia 1. pungent 2. return through lung stomach warm in nature of nature and flavor 3. effect expelling cold, eliminating, clearing the nasal passage.

Cape jasmine 1. nature and flavor：Bitter cold 2. return through：Thoughts of returning home lung liver stomach 3. effect：Heat-clearing, purging intense heat, cool blood.

Raw hawthorn 1. nature and flavor：Acid is sweet, tepor 2. return through：Returns spleen stomach Liver Channel 3. effect：Digestion gathered food, scattered silt blood.

Sculellaria barbata 1. nature and flavor：Arduous cold 2. return through：Return lung liver kidney channel 3. effect：Heat-clearing, removing toxic substances dissipate the stasis of blood, and hemostasis, diuresis disappear It is swollen, analgesic therapy.

Fry Fructus Aurantii 1. nature and flavor：Arduous sour warm 2. return through：Returns spleen stomach 3. effect：Regulating the flow of QI to ease the stomach, the stagnant dissipate-swelling of row, for sternal rib The stagnation of the circulation of vital energy, turgor pain, stops in phlegm and retained fluid.

The tuber of dwarf lilyturf 1. nature and flavor：It is sweet, the cold 2. return through of slight bitter：Thoughts of returning home lung stomach 3. effect：Nourishing Yin and promoting production of body fluid, moistening lung clears away heart-fire are calm, change Mercy function, antitumor action.

The dried rhizome of rehmannia 1. 2. return through thoughts of returning home liver kidney channel sweet in flavor and cold in property 3. effect hemostasis, cardiac stimulant, diuresis are hypoglycemic, enriching yin, cool blood.

The calcined gypsum 1. sweet pungent puckery cold 2. return through return lung stomach 3. effect heat-clearing of nature and flavor, convergence, myogenic, hemostasis.

Lily 1. nature and flavor：Sweet cold 2. return through：Thoughts of returning home lung channel 3. effect：Yin nourishing and lung moistening, clearing away the heart fire and tranquillizing.

The wind-weed 1. nature and flavor bitter cold 2. return through lung stomach kidney channel 3. effect clearing heat-fire, nourshing Yin and drynsessmoistening prescription.

Loguat leaf 1. nature and flavor：Bitter cold 2. return through：Return lung stomach 3. effect：Anti-inflammatory, relievings asthma, removing heat from the lung to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI.

The root of large-flowered skullcap 1. nature and flavor：Bitter cold 2. return through：Thoughts of returning home lung courage large intestine channel 3. effect：Heat-clearing and damp-drying drug, purging intense heat and detonicating, hemostasis are used In evil of vomitting uncomfortable in chest etc..

Cassia twig 1. nature and flavor：Xin Ganwen 2. return throughs：Lung heart bladder warp 3. effect：Inducing sweat and dispelling exogenous evils, eliminating cold to stop pain, activating YANG and prormoting functioning of QI, For many pains such as palpitaition, congealing cold with blood stasis.

Rattletop 1. nature and flavor：Xin Gan is slightly cold 2. return through：Return lung, large intestine, taste Jing 3. effects：Promoting eruption is delivered, it is clearing heat and detoxicating, rise Sun is lifted and is fallen into.

The membrane of a chicken's gizzard 1. nature and flavor：Sweet flat 2. return through：Returns spleen stomach-intestinal bladder warp 3. effect：Reinforcing spleen to promote digestion, arresting seminal emission is treating stranguria Fossil.

The seed of cowherb 1. nature and flavor：Bitter flat 2. return through：Return liver stomach 3. effect：Invigorate blood circulation, lower breast detumescence, inducing diuresis for treating strangurtia.

Radix cyathulae 1. nature and flavor：Sweet, slight bitter equals 2. return through：Return liver kidney channel 3. effect：Stimulate the menstrual flow by silt, easing joint movement, diuresis is led to Drench.

Caulis lonicerae 1. nature and flavor：Sweet cold 2. return through：Return lung stomach 3. effect：It is clearing heat and detoxicating, dispelling wind dredging collateral.

Golden cypress 1. nature and flavor：Bitter cold 2. return through：Return kidney bladder warp 3. effect：Heat-clearing and damp-drying drug, purging intense heat, except steaming, detoxification sore treatment.

Semen Coicis Semen Coicis 1. nature and flavor：Sweet light, be slightly cold 2. return through：Returns spleen lung kidney channel 3. effect：Clearing damp and promoting diuresis, clearing away heat and eliminating pus are good for Spleen antidiarrheal, except numbness is subsided a swelling.

Compared with prior art, the invention has the beneficial effects as follows：

Medicine of the present invention can with it is promoting blood circulation and removing blood stasis for coronary atherosclerosis focus, remove obstruction in channels to relieve pain the effect of, improve Coronary insufficiency, myocardial anoxia, uncomfortable in chest, cardio palmus shape, i.e. relief across clinical coronary disease and angina pectoris bradycardias Situation, and the patient of each age group can use, and its curative effect is superior, is to prevent heart focus preferably new drug at present.This Main prevention coronary heart disease is invented, angina pectoris, bradycardia, the formula can also improve jaundice, tumor manifestations, improve patient body shape Condition, clinical practice safety and there are no bad reaction, can be developed into as new clinical medicine.

Specific embodiment

Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described, Obviously, described embodiment is only a part of embodiment of the invention, rather than the embodiment of whole.Based in the present invention Embodiment, the every other embodiment obtained under the premise of creative work is not made by those of ordinary skill in the art, all Belong to the scope of protection of the invention.

Embodiment 1

It is in the embodiment of the present invention, a kind of to prevent cardiopathic compound preparation, it is made up of the following raw material according to quality：5 grams of radix bupleuri, 5 grams of costus root, green Pericarpium Citri Reticulatae are each 5 grams, 10 grams of giant knotweed, 5 grams of rhubarb, 5 grams of the flower bud of lily magnolia, 10 grams of cape jasmine, 10 grams of raw hawthorn, Sculellaria barbata 10 Gram, fry 5 grams of Fructus Aurantii, 10 grams of the tuber of dwarf lilyturf, 15 grams of the dried rhizome of rehmannia, 10 grams of calcined gypsum, 5 grams of lily, 10 grams of the wind-weed, batch 10 grams of leaf, the root of large-flowered skullcap 5 Gram, 10 grams of cassia twig, 5 grams of rattletop, 15 grams of the membrane of a chicken's gizzard, 8 grams of the seed of cowherb, 5 grams of radix cyathulae, 5 grams of caulis lonicerae, 5 grams of golden cypress, raw Job's tears 5 grams of benevolence.

The preparation method for preventing cardiopathic compound preparation, comprises the following steps：

1）Calcined gypsum is packaged with gauze bag, is put in full-automatic medicine boiling packaging machine cylinder, is put into suitable quantity of water, cross the water surface and forge stone Cream 1.8cm, decocts 25min standby.

2）Again by radix bupleuri, costus root, green Pericarpium Citri Reticulatae, giant knotweed, the flower bud of lily magnolia, cape jasmine, raw hawthorn, Sculellaria barbata, stir-fry Fructus Aurantii, the tuber of dwarf lilyturf, life Ground, lily, the wind-weed, batch leaf, the root of large-flowered skullcap, cassia twig, rattletop, the membrane of a chicken's gizzard, the seed of cowherb, radix cyathulae, caulis lonicerae, golden cypress, raw Job's tears Benevolence gauze bag is put into above-mentioned steps 1 after packaging）Full-automatic medicine boiling packaging machine cylinder in, water level flooded above-mentioned raw materials 1.5cm；Then intense fire is boiled, then is cooked by slow fire 20min；Again rhubarb gauze bag is packaged and is put in cylinder, decoct 3-10 point Clock, filters to take filtrate, pours into packaging bag and obtains final product compound preparation.

Wherein, radix bupleuri, costus root, green Pericarpium Citri Reticulatae, giant knotweed, the flower bud of lily magnolia, cape jasmine, raw hawthorn, Sculellaria barbata, stir-fry Fructus Aurantii, the tuber of dwarf lilyturf, life Ground, lily, the wind-weed, batch leaf, the root of large-flowered skullcap, cassia twig, rattletop, the membrane of a chicken's gizzard, the seed of cowherb, radix cyathulae, caulis lonicerae, golden cypress, raw Job's tears Benevolence needs to soak 20min before addition.

Embodiment 2

It is in the embodiment of the present invention, a kind of to prevent cardiopathic compound preparation, it is made up of the following raw material according to quality：Radix bupleuri 10 Gram, 10 grams of costus root, green Pericarpium Citri Reticulatae are each 10 grams, 20 grams of giant knotweed, 10 grams of rhubarb, 15 grams of the flower bud of lily magnolia, 20 grams of cape jasmine, 20 grams of raw hawthorn, 20 grams of Sculellaria barbata, fries 10 grams of Fructus Aurantii, and 20 grams of the tuber of dwarf lilyturf, 25 grams of the dried rhizome of rehmannia, 20 grams of calcined gypsum, 15 grams of lily, 20 grams of the wind-weed are criticized leaf 20 Gram, 15 grams of the root of large-flowered skullcap, 20 grams of cassia twig, 15 grams of rattletop, 25 grams of the membrane of a chicken's gizzard, 13 grams of the seed of cowherb, 10 grams of radix cyathulae, 15 grams of caulis lonicerae, 10 grams of golden cypress, 10 grams of Semen Coicis Semen Coicis.

1）Calcined gypsum is packaged with gauze bag, is put in full-automatic medicine boiling packaging machine cylinder, is put into suitable quantity of water, cross the water surface and forge stone Cream 2.5cm, decocts 35min standby.

2）Again by radix bupleuri, costus root, green Pericarpium Citri Reticulatae, giant knotweed, the flower bud of lily magnolia, cape jasmine, raw hawthorn, Sculellaria barbata, stir-fry Fructus Aurantii, the tuber of dwarf lilyturf, life Ground, lily, the wind-weed, batch leaf, the root of large-flowered skullcap, cassia twig, rattletop, the membrane of a chicken's gizzard, the seed of cowherb, radix cyathulae, caulis lonicerae, golden cypress, raw Job's tears Benevolence gauze bag is put into above-mentioned steps 1 after packaging）Full-automatic medicine boiling packaging machine cylinder in, water level flooded above-mentioned raw materials 3cm；Then intense fire is boiled, then is cooked by slow fire 60min；Again rhubarb gauze bag is packaged and is put in cylinder, decocted 10 minutes, mistake Leaching filtrate, pours into packaging bag and obtains final product compound preparation.

Wherein, radix bupleuri, costus root, green Pericarpium Citri Reticulatae, giant knotweed, the flower bud of lily magnolia, cape jasmine, raw hawthorn, Sculellaria barbata, stir-fry Fructus Aurantii, the tuber of dwarf lilyturf, life Ground, lily, the wind-weed, batch leaf, the root of large-flowered skullcap, cassia twig, rattletop, the membrane of a chicken's gizzard, the seed of cowherb, radix cyathulae, caulis lonicerae, golden cypress, raw Job's tears Benevolence needs to soak 60min before addition.

Embodiment 3

It is in the embodiment of the present invention, a kind of to prevent cardiopathic compound preparation, it is made up of the following raw material according to quality：7 grams of radix bupleuri, 7 grams of costus root, green Pericarpium Citri Reticulatae are each 7 grams, 12 grams of giant knotweed, 7 grams of rhubarb, 7 grams of the flower bud of lily magnolia, 12 grams of cape jasmine, 12 grams of raw hawthorn, Sculellaria barbata 12 Gram, fry 7 grams of Fructus Aurantii, 12 grams of the tuber of dwarf lilyturf, 16 grams of the dried rhizome of rehmannia, 12 grams of calcined gypsum, 7 grams of lily, 12 grams of the wind-weed, batch 12 grams of leaf, the root of large-flowered skullcap 7 Gram, 12 grams of cassia twig, 7 grams of rattletop, 16 grams of the membrane of a chicken's gizzard, 9 grams of the seed of cowherb, 7 grams of radix cyathulae, 7 grams of caulis lonicerae, 7 grams of golden cypress, raw Job's tears 7 grams of benevolence.

1）Calcined gypsum is packaged with gauze bag, is put in full-automatic medicine boiling packaging machine cylinder, is put into suitable quantity of water, cross the water surface and forge stone Cream 2cm, decocts 305min standby.

2）Again by radix bupleuri, costus root, green Pericarpium Citri Reticulatae, giant knotweed, the flower bud of lily magnolia, cape jasmine, raw hawthorn, Sculellaria barbata, stir-fry Fructus Aurantii, the tuber of dwarf lilyturf, life Ground, lily, the wind-weed, batch leaf, the root of large-flowered skullcap, cassia twig, rattletop, the membrane of a chicken's gizzard, the seed of cowherb, radix cyathulae, caulis lonicerae, golden cypress, raw Job's tears Benevolence gauze bag is put into above-mentioned steps 1 after packaging）Full-automatic medicine boiling packaging machine cylinder in, water level flooded above-mentioned raw materials 2cm；Then intense fire is boiled, then is cooked by slow fire 40min；Again rhubarb gauze bag is packaged and is put in cylinder, decocted 6 minutes, mistake Leaching filtrate, pours into packaging bag and obtains final product compound preparation.

Wherein, radix bupleuri, costus root, green Pericarpium Citri Reticulatae, giant knotweed, the flower bud of lily magnolia, cape jasmine, raw hawthorn, Sculellaria barbata, stir-fry Fructus Aurantii, the tuber of dwarf lilyturf, life Ground, lily, the wind-weed, batch leaf, the root of large-flowered skullcap, cassia twig, rattletop, the membrane of a chicken's gizzard, the seed of cowherb, radix cyathulae, caulis lonicerae, golden cypress, raw Job's tears Benevolence needs to soak 40min before addition.

Embodiment 4

It is in the embodiment of the present invention, a kind of to prevent cardiopathic compound preparation, it is made up of the following raw material according to quality：9 grams of radix bupleuri, 9 grams of costus root, green Pericarpium Citri Reticulatae are each 9 grams, 16 grams of giant knotweed, 9 grams of rhubarb, 11 grams of the flower bud of lily magnolia, 16 grams of cape jasmine, 16 grams of raw hawthorn, Sculellaria barbata 16 grams, fry 9 grams of Fructus Aurantii, 16 grams of the tuber of dwarf lilyturf, 22 grams of the dried rhizome of rehmannia, 16 grams of calcined gypsum, 11 grams of lily, 16 grams of the wind-weed, batch 16 grams of leaf, the root of large-flowered skullcap 11 grams, 16 grams of cassia twig, 11 grams of rattletop, 22 grams of the membrane of a chicken's gizzard, 12 grams of the seed of cowherb, 9 grams of radix cyathulae, 11 grams of caulis lonicerae, 9 grams of golden cypress, 9 grams of Semen Coicis Semen Coicis.

Preparation process is consistent with embodiment 3.

Embodiment 5

It is in the embodiment of the present invention, a kind of to prevent cardiopathic compound preparation, it is made up of the following raw material according to quality：8 grams of radix bupleuri, 8 grams of costus root, green Pericarpium Citri Reticulatae are each 8 grams, 14 grams of giant knotweed, 8 grams of rhubarb, 9 grams of the flower bud of lily magnolia, 14 grams of cape jasmine, 14 grams of raw hawthorn, Sculellaria barbata 14 Gram, fry 8 grams of Fructus Aurantii, 14 grams of the tuber of dwarf lilyturf, 19 grams of the dried rhizome of rehmannia, 14 grams of calcined gypsum, 9 grams of lily, 14 grams of the wind-weed, batch 14 grams of leaf, the root of large-flowered skullcap 9 Gram, 14 grams of cassia twig, 9 grams of rattletop, 19 grams of the membrane of a chicken's gizzard, 11 grams of the seed of cowherb, 8 grams of radix cyathulae, 9 grams of caulis lonicerae, 8 grams of golden cypress, the raw heart of a lotus seed 8 grams of the seed of jog's tears.

Preparation process is consistent with embodiment 3.

Where should be noted in the preparation process of compound preparation of the present invention：

1. it is decocted first：Calcined gypsum, calcined gypsum is packaged with gauze bag, is put in full-automatic medicine boiling packaging machine cylinder, is put into suitable quantity of water, Calcined gypsum quality density is made, water absorbing properties are good, the water surface should be crossed calcined gypsum about 2cm and be advisable, decocted 30 minutes or so.

2. add water how many：23 kinds of Chinese medicine gauze bags will be put in cylinder after packaging in addition to rhubarb again, amount of water is how many Should be according to the water absorption of medicine materical crude slice how much by theoretical reckoning, the summation of evaporation capacity and the amount of liquid medicine needed for after decocting in decoction process, Although practical operation adds water to be difficult to accomplish exactly accurate, at least will be according to when the quality density of medicine materical crude slice, water absorbing properties and decoction Between length determine add water how many, general water consumption be by medicine materical crude slice appropriate pressurization after, liquid level flooded medicine materical crude slice 2cm and was advisable.

3. soak before boiling medicine：Immersion before the prepared slices of Chinese crude drugs are decocted not only improves active ingredient and is fully dissolved out, and can shorten decoction again Time, it is to avoid because decocting time is long, cause part active ingredient consume, destruction is excessive.Most medicines preferably use cold water soak, can Soak 20～30 minutes, the medicine based on suitable fruit can soak 1 hour, summer temperature is high, soak time is unsuitable long, so as not to it is corrupt It is rotten.

4. decoct the duration and degree of heating and time：Decocting herb should also be noted that the duration and degree of heating is suitable with decocting time.Decoct general medicine preferably elder generation's intense fire Slow fire, i.e. at a simmer front use big fire afterwards, keeps slight boiling condition with small fire after boiling, in case concoction overflows or too fast boils dry.

5. afterwards under：Rhubarb, rhubarb gauze bag is packaged and is put in cylinder, decocts a few minutes.

6. decoct number of times：In general, dose can be decocted three times, should at least decoct twice because when boiling medicine medicine effectively into Divide and can be dissolved in in the aqueous of medicinal material tissue first, be then diffused into again in the aqueous outside medicinal material.It is molten to inside and outside medicinal material When the concentration of liquid reaches balance, because of osmotic balance, active ingredient just no longer dissolution.

7. marc takes juice：Preparation answers marc to take juice after decocting, because general medicine can all adsorb certain after adding water to cook Liquid.Secondly the active ingredient in main liquid may be adsorbed again by the dregs of a decoction.Abandon if the dregs of a decoction are without pressure extracting juice, can cause Effect component damages, especially in the dregs of a decoction, contained active ingredient proportion can be bigger, and the meaning that marc takes juice is just bigger.

8. liquid is poured into packaging bag automatically.

Instructions of taking of the present invention：A day three times, once a bag.

Embodiment 6

1st, case is collected：Selection meets coronary heart disease and arrhythmia patient 100, is randomly divided into treatment group 50 and control group 50 Example, age are 35～72, the course of disease 1～5 year.

2nd, medication：Treatment group：The embodiment of the present invention 5 is taken, a day three times, once a bag, one bag of 10mL；Control group： Oral triacylglycerol piece, three pieces/times, 3 times/d.The course for the treatment of is 2 months.Period cuts out all anti-arrhythmias and anti-blood is little Plate aggregation etc. improves hemorheological medicine.Improvement situation before and after observed and recorded treatment, ECG curative effect, Hemorheology Index.

3rd, check：Blood fat to patient, heart function, clinical manifestation observation.Before treatment, 12 lead electrocardiogram of record improve feelings The relevant inspection of condition and heart, carries out Electrocardiographic check after medication two weeks or four weeks, and while carries out cardiac auscultation.Often 2min/ time.

4th, efficacy assessment standard：It is effective：Cardiac auscultation 2min, premature beat reduce more than 90%, send out into Electrocardioscopy without premature beat Existing, atrial fibrillation switchs to sinus rhythm；Effectively：Cardiac auscultation 2min, premature beat reduce more than 50%, into Electrocardioscopy premature beat by taking place frequently Aim at it is accidental, chamber in short town occur；It is invalid：After four weeks after taking, it is not improved.

5th, result：Electrocardiogram compares discovery, and treatment group improves situation and is better than control group, and treatment group's 12 lead synchronization heart The inspection result of electrograph is：Sinus rhythm, substantially normal ECG.Show that the compound preparation of present invention offer can obviously improve the heart Vascular function and brain microcirculation function, rapid-action, length of holding time.

It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie In the case of spirit or essential attributes without departing substantially from the present invention, the present invention can be realized in other specific forms.Therefore, no matter From the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, the scope of the present invention is by appended power Profit is required rather than described above is limited, it is intended that all in the implication and scope of the equivalency of claim by falling Change is included in the present invention.

It is divided into major ingredient and auxiliary material, wherein major ingredient in the formula：The tuber of dwarf lilyturf, caulis lonicerae, raw hawthorn, the dried rhizome of rehmannia, cassia twig, the flower bud of lily magnolia, life Coix seed, Sculellaria barbata, cape jasmine, the seed of cowherb, the membrane of a chicken's gizzard, radix cyathulae.

Major ingredient effect；The tuber of dwarf lilyturf, raw hawthorn are to treat angina pectoris, arrhythmia cordis；The dried rhizome of rehmannia to promoting blood circulation and removing blood stasis, with Wang Buliu Row, radix cyathulae coordinate can treat pectoralgia；Cassia twig, the flower bud of lily magnolia coordinate can treat chill, reach the purpose of promoting the circulation of qi promoting circulation of blood；Use Semen Coicis Semen Coicis Supplement healthy tendency, strengthening vital QI to eliminate pathogenic factors；Enzyme drops in cape jasmine removing jaundice, and the membrane of a chicken's gizzard, Sculellaria barbata are soft to harden, and caulis lonicerae is promoting blood circulation and removing blood stasis.

Auxiliary material：The wind-weed, calcined gypsum, fry Fructus Aurantii, golden cypress, costus root, giant knotweed, process batch leaf, scutellaria, rattletop, lily, green grass or young crops old Skin, radix bupleuri, rhubarb.

Auxiliary material effect：Calcined gypsum hygroscopic, myogenic, lily are protected the five internal organs, beneficial gas, nourish cloudy liquid, calm the nerves, moisten liquid；Fry Fructus Aurantii blue or green Dried orange peel, giant knotweed are qi-regulating drug, treat distending pain；Rattletop, radix bupleuri, fry Fructus Aurantii compatibility all one's life one and drop, to help the solid row of qi and blood, have beneficial gas, Rise effect of resistance；Cape jasmine is with the root of large-flowered skullcap, golden cypress, rhubarb, fiery poison is flourishing, clearing heat and detoxicating for wind-weed treatment, the heart is hot vexed, annealing of calming the nerves； Costus root, giant knotweed, qi-regulating are treatment qi and blood retardance, promoting blood circulation and removing blood stasis, and effect more preferably, finally with processing batch gas under leaf, drain by rheum officinale, Reach normal metabolism, equilibrium between yin and yang.

Moreover, it will be appreciated that although this specification is been described by according to embodiment, not each embodiment is only wrapped Containing an independent technical scheme, this narrating mode of specification is only that those skilled in the art should for clarity Using specification as an entirety, the technical scheme in each embodiment can also Jing it is appropriately combined, form those skilled in the art Understandable other embodiment.

Claims

1. it is a kind of to prevent cardiopathic compound preparation, it is characterised in that to be made up of the following raw material according to quality：Radix bupleuri 5-10 Gram, 5-10 gram of costus root, green Pericarpium Citri Reticulatae are each 5-10 gram, 10-20 gram of giant knotweed, 5-10 gram of rhubarb, 5-15 gram of the flower bud of lily magnolia, cape jasmine 10-20 Gram, raw hawthorn 10-20 gram, 10-20 gram of Sculellaria barbata fry 5-10 gram of Fructus Aurantii, 10-20 gram of the tuber of dwarf lilyturf, 15-25 gram of the dried rhizome of rehmannia, calcined gypsum 10- 20 grams, 5-15 gram of lily, 10-20 gram of the wind-weed, batch 10-20 gram of leaf, 5-15 gram of the root of large-flowered skullcap, 10-20 gram of cassia twig, 5-15 gram of rattletop, 15-25 gram of the membrane of a chicken's gizzard, 8-13 gram of the seed of cowherb, 5-10 gram of radix cyathulae, 5-15 gram of caulis lonicerae, 5-10 gram of golden cypress, Semen Coicis Semen Coicis 5- 10 grams.

2. it is according to claim 1 to prevent cardiopathic compound preparation, it is characterised in that by the following raw material according to quality Composition：7-9 gram of radix bupleuri, 7-9 gram of costus root, green Pericarpium Citri Reticulatae are each 7-9 gram, 12-16 gram of giant knotweed, 7-9 gram of rhubarb, 7-11 gram of the flower bud of lily magnolia, 12-16 gram of cape jasmine, raw hawthorn 12-16 gram, 12-16 gram of Sculellaria barbata, 7-9 gram of Fructus Aurantii of stir-fry, 12-16 gram of the tuber of dwarf lilyturf, 16-22 gram of the dried rhizome of rehmannia, 12-16 gram of calcined gypsum, 7-11 gram of lily, 12-16 gram of the wind-weed, batch 12-16 gram of leaf, 7-11 gram of the root of large-flowered skullcap, 12-16 gram of cassia twig, liter Numb 7-11 gram, 16-22 gram of the membrane of a chicken's gizzard, 9-12 gram of the seed of cowherb, 7-9 gram of radix cyathulae, 7-11 gram of caulis lonicerae, 7-9 gram of golden cypress, the raw heart of a lotus seed 7-9 gram of the seed of jog's tears.

3. it is according to claim 2 to prevent cardiopathic compound preparation, it is characterised in that by the following raw material according to quality Composition：8 grams of radix bupleuri, 8 grams of costus root, green Pericarpium Citri Reticulatae are each 8 grams, 14 grams of giant knotweed, 8 grams of rhubarb, 9 grams of the flower bud of lily magnolia, 14 grams of cape jasmine, raw hawthorn 14 grams, 14 grams of Sculellaria barbata fries 8 grams of Fructus Aurantii, 14 grams of the tuber of dwarf lilyturf, 19 grams of the dried rhizome of rehmannia, 14 grams of calcined gypsum, 9 grams of lily, 14 grams of the wind-weed, batch handle 14 grams of leaf, 9 grams of the root of large-flowered skullcap, 14 grams of cassia twig, 9 grams of rattletop, 19 grams of the membrane of a chicken's gizzard, 11 grams of the seed of cowherb, 8 grams of radix cyathulae, 9 grams of caulis lonicerae, 8 grams of golden cypress, 8 grams of Semen Coicis Semen Coicis.

4. a kind of preparation method of the cardiopathic compound preparation of prevention as described in claim 1-3 is arbitrary, it is characterised in that bag Include following steps：

5. the preparation method of the cardiopathic compound preparation of prevention according to claim 4, it is characterised in that step 2）In, Radix bupleuri, costus root, green Pericarpium Citri Reticulatae, giant knotweed, the flower bud of lily magnolia, cape jasmine, raw hawthorn, Sculellaria barbata, fry Fructus Aurantii, the tuber of dwarf lilyturf, the dried rhizome of rehmannia, lily, the wind-weed, batch Leaf, the root of large-flowered skullcap, cassia twig, rattletop, the membrane of a chicken's gizzard, the seed of cowherb, radix cyathulae, caulis lonicerae, golden cypress, Semen Coicis Semen Coicis are needed immersion before addition 20-60min。

6. the preparation method of the cardiopathic compound preparation of prevention according to claim 5, it is characterised in that step 1）In, Radix bupleuri, costus root, green Pericarpium Citri Reticulatae, giant knotweed, the flower bud of lily magnolia, Sculellaria barbata, fry Fructus Aurantii, the tuber of dwarf lilyturf, the dried rhizome of rehmannia, lily, the wind-weed, batch leaf, the root of large-flowered skullcap, osmanthus Branch, rattletop, the membrane of a chicken's gizzard, the seed of cowherb, radix cyathulae, caulis lonicerae, golden cypress soak 20-30min before addition；Cape jasmine, raw hawthorn, life Coix seed soaks 60min before addition.

7. the preparation method of the cardiopathic compound preparation of prevention according to claim 4, it is characterised in that cross the water surface and forge Gypsum 2cm.

8. the preparation method of the cardiopathic compound preparation of prevention according to claim 4, it is characterised in that step 2）In, Water level flooded above-mentioned raw materials 2cm.

9. the preparation method of the cardiopathic compound preparation of prevention according to claim 4, it is characterised in that step 2）In, Step 2）In, the mode of filtration takes juice using marc.

10. the preparation method of the cardiopathic compound preparation of prevention according to claim 4, it is characterised in that step 2）In, Repeat step 2）Decoction, filter process 1-2 time.