CN101283757B - Nutrient soya-bean milk and its preparation method - Google Patents
Nutrient soya-bean milk and its preparation method Download PDFInfo
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- CN101283757B CN101283757B CN2008100644198A CN200810064419A CN101283757B CN 101283757 B CN101283757 B CN 101283757B CN 2008100644198 A CN2008100644198 A CN 2008100644198A CN 200810064419 A CN200810064419 A CN 200810064419A CN 101283757 B CN101283757 B CN 101283757B
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Abstract
The invention discloses a method for producing a nutritious soybean milk which is made from major ingredients including soybean, vitamin B12, vitamin D, taurine and calcium and adjuvant ingredients including pueraria root, cinnamon bark, folic acid, beta-cyclodextrin and flavoring agent. The method comprises the following steps: soaking soybean and draining or soaking soybean, dehulling and draining; freezing at low temperature; mixing with other ingredients; blending to obtain a slurry with bean cake particle size less than or equal to 50 micrometers and protein content more than or equal to2%; homogenizing; boiling to obtain nutritious soybean milk; and optionally further concentrating and drying to obtain nutritious soybean milk powder. The product can relieve the adverse effect of hypoglycemic drugs and prevent diabetes complications.
Description
(1) technical field
The present invention relates to foods processing technique, be specifically related to a kind of with soybean, Cobastab
12, vitamin D, taurine, edible calcium be the nutrient soya-bean milk technology of main component processing.
(2) background technology
The chemical sugar-lowering medicine is in the treatment diabetes, and its toxic and side effect causes damage to patient health.Hypoglycemic medicine is lifelong medication, but how to reduce and prevent the research of chemical sugar-lowering medicine toxic and side effect very few, to such an extent as to the diabetic must suffer from the chemicals toxic and side effect throughout one's life.
At present, global drug surveillance warning: hypoglycemic medicine melbine commonly used causes Cobastab
12Shortage, Rosiglitazone cause heart change and osteoporosis.
Past knows that just the patient takes melbine and causes Cobastab
12Lack, clinical pharmacy is clearly warned now: along with the prolongation of taking the melbine time, the patient is because of Cobastab
12Shortage and malabsorption and bring disaster to hemopoietic function of bone marrow cause macrocytic anemia, the epithelial function of complete and digestive system that endangers neural myelin, liver injury tissue.Not long ago, ADA (ADA) and European diabetes association (EASD) standard melbine were the lifelong medications of diabetes, in order to reduce and even to prevent melbine toxic and side effect, replenishing vitamins B
12Essential.
U.S.'s " New England Journal of Medicine " report, U.S. scientist has carried out comparative study to 1.56 ten thousand diabetic and 1.23 ten thousand patients that take other diabetes medicaments that take " Avandia " (Rosiglitazone), found that, take " Avandia " and can make the onset risk of patient's heart disease improve 43%, and make patient's deaths from heart disease rate improve 64%.As a kind of insulin sensitizer; " Avandia " uses very extensive clinically; but the bad patient of cardiac function uses this medicine may cause anasarca; and female patient is many than the male sex; easier inducing reaction, particularly women with diabetes must pay attention to protecting heart when this medicine and insulin share.
Recently, NIH delivers report at " Nature Journal " and points out, the most frequently used medicine Avandia (Rosiglitazone) of treatment diabetes B can cause osteoporosis, increases risk of bone fracture.GlaxoSmithKline PLC company is admitted when this medicine of marketing, discovers the women who takes this medicine, higher risk of bone fracture can occur.The epidemiology survey data shows, compares with the ordinary people, and the diabetes patient urinates many one times of calcium loss, and the dangerous of the osteoporotic incidence of disease of diabetic and osteoporotic fracture obviously increases.In the complication of diabetes, the complication of systems such as the heart, brain, kidney, eye and skin, nerve generally has been familiar with, but diabetes complicated osteoporosis is just to begin in recent years to be familiar with by medical circle.In fact, diabetes complicated osteoporosis is a common chronic complicating diseases of diabetes, and 50% concurrent osteoporosis is arranged among the report diabetics such as Levin, but how the patient is to preventing and treating diabetes complicated osteoporotic lack of knowledge.And osteoporosis is in case generation is irreversible, so it is particularly important to seem aspect prevention.Osteoporosis easily causes fracture, causes very big difficulty for patient treatment and rehabilitation, and the disability rate height increases the weight of patient economy burden, and patient's quality of life is descended.The minimizing of type 1 diabetes patient bone amount and the osteoporotic incidence of disease are up to 48%～72%, and the incidence of disease of suffering from women's fracture of type 1 diabetes is 12～25 times of non-diabetic women.The osteoporotic incidence of disease of diabetes B patient is about 50%～60%.The old women of suffering from diabetes B is faster than non-diabetic women and male sex's bone loss, and the fracture incidence of disease also obviously increases, and state Nei Huangshi report diabetes fracture patient 5 annual death rates are 15%.Therefore, the diabetes patient replenishes the calcium, and is for essential for reducing hypoglycemic medicine side effect and prevention of osteoporosis.
Therefore, invention can reduce and prevent melbine and Rosiglitazone toxic and side effect and diabetic complication and convenient often edible nutrient soya-bean milk, and is very useful to diabetes patient's health care.
(3) summary of the invention
The object of the present invention is to provide and a kind ofly reduce and nutrient soya-bean milk of prevention hypoglycemic medicine side effect and diabetic complication and preparation method thereof by nutritional supplementation.
The object of the present invention is achieved like this: nutrient soya-bean milk comprises mass component than being soybean 1kg, Cobastab
1230-500ug, VD4 0-100ug, folic acid 1-6mg, taurine 30-150g, edible calcium 1-8g, Chinese cassia tree 10-30g, root of kudzu vine 100-500g, B-cyclodextrin 10-80g and flavor enhancement 1-300g.
The preparation method of this nutrient soya-bean milk is:
Step 1: raw material, processing
1. soybean 1kg is soaked in water drained in 12-48 hour, or with soybean 1kg beans be soaked in water 12-48 hour the peeling after drain ,-18 ℃ of following temperature were freezed 4-12 hour;
2. Chinese cassia tree 10-30g is mixed with root of kudzu vine 100-500g, pulverize, pouring mass ratio 10-20 times concentration into is to soak 12-24 hour in the 3-10% limewash, remove slag, soak adds concentration and transfers pH2-3 for the 30-50% sulfuric acid solution, leaves standstill 12-24 hour, the elimination sediment, get clarified solution, it is that the 10-20% sodium hydroxide solution is transferred pH7-8 that clarified solution adds concentration, gets Chinese cassia tree root of kudzu vine extract;
3. Cobastab
1230-500ug, VD4 0-100ug, folic acid 1-6mg, taurine 30-150g, calcium carbonate 1-8g, B-cyclodextrin 10-80g, flavor enhancement 1-300g, standby.
Step 2: defibrination, homogeneous
With freezing soybean 1kg, water 10-20L, 0.5-1L Chinese cassia tree root of kudzu vine extract, Cobastab
1230-500ug, VD4 0-100ug, folic acid 1-6mg, taurine 30-150g, calcium carbonate 1-8g, B-cyclodextrin 10-80g, flavor enhancement 1-300g mix, defibrination, homogeneous, bean dregs particle diameter≤50 micron, the emulsion of protein 〉=2%;
Step 3: concentrate and obtain finished product.
Preparation method of the present invention also has some technical characterictics like this:
1, described edible calcium is a calcium carbonate, also can be the mixture of the wherein a kind of of calcium citrate, calcium gluconae, calcium lactate, calcium monohydrogen phosphate or at least two kinds;
1, freezed 4-12 hour-18 ℃ of following temperature after defilming soybean drains in the described step 1;
2, in the described step 3 emulsion is boiled, get liquid wholegrain nutrient soya-bean milk;
3, in the described step 3 wholegrain nutrient soya-bean milk is concentrated, drying gets solid wholegrain nutrient soya-bean milk;
4, in the described step 3 emulsion is removed the gred, boil, getting liquid does not have the slag nutrient soya-bean milk;
5, in the described step 3 wholegrain nutrient soya-bean milk is concentrated, the slagging-off back is dry, gets the solid no-residue nutrient soya-bean milk.
The present invention relates to soybean, Cobastab
12, vitamin D, Taurine, calcium etc. be main component; with Chinese cassia tree, the root of kudzu vine, folic acid, B-cyclodextrin, flavor enhancement etc. is the preparation method of auxiliary element processing nutrient soya-bean milk, can reduce and prevention hypoglycemic medicine side effect and diabetic complication by nutritional supplementation.
Studies show that in a large number both at home and abroad:
1. can promote Cobastab by replenishing the calcium
12Absorb, also can promote Cobastab by Supplement of folic acid
12Absorb, and folic acid and Cobastab
12The anti-anaemia effect of Synergistic is arranged;
2. soybean contains abundant isoflavones, and the effect of its anti-osteoporosis is generally acknowledged by medical circle;
3. the isoflavone content that contains of the root of kudzu vine than the high 6-8 of soybean doubly and can have the effect of hypoglycemic, step-down, lipopenicillinase, treatment BDR in anti-osteoporosis;
4. calcium and vitamin D replenish simultaneously and can promote calcium to absorb.
5. current research is found, the of paramount importance health advantages of Chinese cassia tree is the preventive and therapeutic effect to diabetes, be rich in sugar reducing substance Chinese cassia tree methylol chalcone in the Chinese cassia tree, zoopery and crowd for the U.S. and China uses proof diabetes B had remarkable blood sugar reducing function, U.S.'s " diabetes care magazine " delivers report and point out that the diabetes B people adds (1-3g) ground cinnamon every day can significantly reduce blood sugar level in beverage.
6. Recent study is found; taurine is regulated body osmotic pressure and Primary Care effect such as anti-oxidant by it; can wholely prevent and treat diabetes four big complication such as cardio cerebrovascular affection, ephrosis change, eyes pathology, DPN; and constantly in zoopery and clinical research, be confirmed, will bring into play independently nutrition treatment advantage for solving the clinical difficult problem of diabetic complication.
7. the ability of human body synthesizing taurine is very weak, and main dependence absorbed from meals.Kidney can be regulated the taurine discharge rate, to keep taurine balance in the body according to content of taurine in body needs and the meals.Taurine in the adjusting of system's physiological functions such as the digestion of body, reproduction, immunity, nerve, endocrine, keep in the homeostasis of body tissue cell and play an important role.
1. to the protective effect of B cell: the prophylactic use taurine can obviously suppress the IDDM animal model blood sugar level that Streptozotocin (STZ) induces and raise; IL-1B can suppress B emiocytosis function, and taurine then can resist the inhibition of IL-1B to insulin secretion, and its reversal effect has dose-effect and time-effect relationship.
2. prevention and control diabetic cardiopathy: studies show that; cardiac muscular tissue's renin angiotensin (RAS) hyperfunction participates in the myocardiac evolution of diabetic keratopathy; taurine can pass through to suppress the function of RAS system of diabetes rat cardiac muscular tissue, thereby plays the effect that alleviates the diabetes cardiac damage.
3. prevention and control diabetic nephropathy: under the physiological status, what of food-intake kidney can by regulating the heavily absorption of near-end renal tubule to taurine, make the taurine level in the body keep balance according to.Supplementation of taurine can make the albuminuria of diabetic nephropathy SD rat reduce by 50%, alleviates glomerulus hypertrophy, glomerulus interstitial fibers hyperplasia, glomerulosclerosis.Taurine is to the improvement effect of diabetes rat kidney 26S Proteasome Structure and Function, and the formation that reduces kidney cortex MDA (MDA) content, reduction free serum Fe++ content, minimizing glycosylation dead end product with taurine is relevant.Taurine still can play the synthetic of inhibition diabetic glomeruli extracellular matrix (ECM) by reducing rat cortex renis glycosylation dead end product (AGEs) formation and TGF-B gene expression, thereby alleviates the nephridial tissue damage.
4. prevention and control diabetic cataract: the pathogenesis of diabetic cataract comprises polyalcohol path, osmotic pressure theory and oxidation theory.Taurine has regulates crystal osmotic pressure and important function such as anti-oxidant.Take place in the process of development at diabetic cataract, sorbitol content increases, crystal osmotic pressure increases, and obviously reduces as the content of taurine of regulating the osmotic pressure important substance, and antioxidation weakens, albumen generation over oxidation in the crystal, thus cause or increase the weight of cataractous the development; Supplementation of taurine can suppress the mechanism of the generation development of diabetic cataract, may be relevant with the inhibition hyperglycaemia with its anti-oxidation function.
5. prevent and treat diabetic neuropathy: along with content of taurine in the diabetic neuropathy animal model descends, MNCV and then descends.Taurine is as antioxidant, calcium regulator and vasodilator, and it reduces with going down of diabetes nerve metabolism and vascular function the Pathogenetics relation.Zoopery proves, supplementation of taurine can reduce blood plasma TXB2, TXB3, reach glycation end product content in the sciatic nerve, increases generation and the content of 6-ketoPGF1 α, improves the sciatic nerve conduction of velocity, alleviate neural pathological change, diabetic neuropathy is had the prevention and control effect; Supplementation of taurine is not directly by reducing blood sugar level to the prevention and control effect of diabete peripheral herve pathology; but by effectively removing free radical; alleviate lipid peroxidation, reduce MDA (MDA), raise nerve growth factor mRNA and express and improve that neurotrosis realizes.
8.B-cyclodextrin can be covered the peculiar smell in the soya-bean milk.
With soybean, Cobastab
12, vitamin D, Taurine, calcium be main component, Chinese cassia tree, the root of kudzu vine, folic acid, B-cyclodextrin, flavor enhancement etc. are auxiliary element, it is edible to be processed into soya-bean milk, is used to alleviate and prevents hypoglycemic medicine toxic and side effect and prevention and control diabetic complication.
(4) specific embodiment
The present invention is further illustrated below in conjunction with specific embodiment:
Embodiment 1:
Soybean 100kg steeped 12-48 hour with 2-3 times of water logging, drained, and-18 ℃ of following temperature were freezed 4-8 hour, must freeze the about 200kg of soybean; Chinese cassia tree 1kg, root of kudzu vine 10kg, mix and pulverize, pour in the 10-20 times of 3-10% limewash and soaked 12-24 hour, remove slag, leaching liquor adds 50% sulfuric acid solution and transfers pH2-3, left standstill 12-24 hour, the elimination sediment gets filtrate, filtrate adds 10% sodium hydroxide solution and transfers pH7-8, gets about 100 liters of root of kudzu vine Chinese cassia tree extract; With freezing soybean 200kg, 1300 liters in water, 100 liters of root of kudzu vine Chinese cassia tree extracts, Cobastab
123mg, VD4 mg, folic acid 200mg, taurine 6kg, calcium carbonate 500g, B-cyclodextrin 5kg, flavor enhancement 200g.Mix, petty slurry, homogeneous boils, bean dregs particle diameter≤50 micron, the liquid wholegrain nutrient soya-bean milk of protein 〉=2%.
Embodiment 2:
Present embodiment basic structure is with embodiment 1, and difference is the wholegrain nutrient soya-bean milk elimination bean dregs with embodiment 1, and getting liquid does not have the slag nutrient soya-bean milk.
Embodiment 3:
Present embodiment basic structure is with embodiment 1, and difference is the wholegrain nutrient soya-bean milk of embodiment 1 is concentrated, and drying gets solid wholegrain nutrient soya-bean milk.
Embodiment 4:
Present embodiment basic structure is with embodiment 1, and difference is that the liquid with embodiment 2 does not have the slag nutrient soya-bean milk and concentrates, drying, the solid no-residue nutrient soya-bean milk.
Embodiment 5:
Soybean 100kg steeped 12-48 hour with 2-3 times of water logging, and peeling drains, and-18 ℃ of following temperature were freezed 4-8 hour, must freeze the about 200kg of soybean; Chinese cassia tree 1kg, root of kudzu vine 10kg, mix and pulverize, pour in the 10-20 times of 3-10% limewash and soaked 12-24 hour, remove slag, leaching liquor adds 30% sulfuric acid solution and transfers pH2-3, left standstill 12-24 hour, the elimination sediment gets filtrate, filtrate adds 10% sodium hydroxide solution and transfers pH7-8, gets about 100 liters of root of kudzu vine Chinese cassia tree extract; With freezing soybean 200kg, 1300 liters in water, 100 liters of root of kudzu vine Chinese cassia tree extracts, Cobastab
123mg, VD4 mg, folic acid 200mg, taurine 6kg, calcium carbonate 500g, B-cyclodextrin 5kg, flavor enhancement 200g.Mix, defibrination, homogeneous boils, bean dregs particle diameter≤50 micron, the liquid wholegrain nutrient soya-bean milk of protein 〉=2%.
Embodiment 6:
Present embodiment basic structure is with embodiment 5, and difference is the wholegrain nutrient soya-bean milk of embodiment 5 is concentrated, and drying gets solid wholegrain nutrient soya-bean milk.
Embodiment 7:
Present embodiment basic structure is with embodiment 5, and difference is the wholegrain nutrient soya-bean milk elimination bean dregs with embodiment 5, and getting liquid does not have the slag nutrient soya-bean milk.
Embodiment 8:
Present embodiment basic structure is with embodiment 5, and difference is the no slag nutrient soya-bean milk of embodiment 7 is concentrated, and drying gets solid-state no slag nutrient soya-bean milk.
Claims (4)
1. the preparation method of a nutrient soya-bean milk is characterized in that:
Soybean 100kg steeped 12-48 hour with 2-3 times of water logging, drained, and-18 ℃ of following temperature were freezed 4-8 hour, must freeze soybean 200kg; Chinese cassia tree 1kg, root of kudzu vine 10kg, mix and pulverize, pour in the 10-20 times of 3-10% limewash and soaked 12-24 hour, remove slag, leaching liquor adds 50% sulfuric acid solution and transfers pH2-3, left standstill 12-24 hour, the elimination sediment gets filtrate, filtrate adds 10% sodium hydroxide solution and transfers pH7-8, gets 100 liters of root of kudzu vine Chinese cassia tree extracts; With freezing soybean 200kg, 1300 liters in water, 100 liters of root of kudzu vine Chinese cassia tree extracts, cobalamin 3mg; vitamin D 4mg; folic acid 200mg, taurine 6kg, calcium carbonate 500g, beta-schardinger dextrin-5kg, flavor enhancement 200g; mix; defibrination, homogeneous boils; bean dregs particle diameter≤50 micron, the liquid wholegrain nutrient soya-bean milk of protein 〉=2%.
2. the preparation method of a kind of nutrient soya-bean milk according to claim 1 is characterized in that, with described wholegrain nutrient soya-bean milk elimination bean dregs, getting liquid does not have the slag nutrient soya-bean milk.
3. the preparation method of a kind of nutrient soya-bean milk according to claim 1 is characterized in that, described liquid wholegrain nutrient soya-bean milk is concentrated, and drying gets solid wholegrain nutrient soya-bean milk.
4. according to claim 1, the prepared a kind of nutrient soya-bean milk of 2 or 3 described a kind of nutrient soya-bean milk preparation methods.
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Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101904351B (en) * | 2010-08-10 | 2012-05-23 | 河北三元食品有限公司 | Antialcoholic sour milk and preparation method thereof |
| CN102793017A (en) * | 2012-08-28 | 2012-11-28 | 张桂毫 | Soybean milk production process |
| CN103349675A (en) * | 2013-03-26 | 2013-10-16 | 郑毅男 | Medical use of vegetable soybeans in diabetes prevention and treatment |
| CN103564057A (en) * | 2013-11-05 | 2014-02-12 | 黎秋萍 | Bean seed germ soybean milk |
| CN103918796A (en) * | 2014-04-24 | 2014-07-16 | 万世凤 | Making method of soya-bean milk |
| CN105076454A (en) * | 2015-09-11 | 2015-11-25 | 安徽恋尚你食品有限公司 | Blood-enriching and face-beautifying soybean milk |
| CN105123960A (en) * | 2015-09-11 | 2015-12-09 | 安徽恋尚你食品有限公司 | Soybean milk capable of tonifying blood, caring skin and beautifying face |
| CN115176971A (en) * | 2022-06-24 | 2022-10-14 | 黑龙江冰泉多多保健食品有限责任公司 | Radix puerariae soybean protein powder with liver protection effect and preparation method thereof |
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