CN101279080B - Medicament composition for curing cervical vertebra disease, lumbar disease and traumatic injury and preparation method - Google Patents
Medicament composition for curing cervical vertebra disease, lumbar disease and traumatic injury and preparation method Download PDFInfo
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- CN101279080B CN101279080B CN2008101145604A CN200810114560A CN101279080B CN 101279080 B CN101279080 B CN 101279080B CN 2008101145604 A CN2008101145604 A CN 2008101145604A CN 200810114560 A CN200810114560 A CN 200810114560A CN 101279080 B CN101279080 B CN 101279080B
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Abstract
The invention discloses a medical combination for curing cervical spondylosis, lumbar spondylosis and traumatic injury and a preparation method thereof. Bulk drugs of the medicine of the invention are angelica, frankincense, myrrh, hemlock parsley, dahurian angelica, herba leonuri, bitter orange, cortex cinnamomi, acanthopanax bark, radices sophorae flavescentis, herba schizeneptae, cortex cereis, ledeboruiella root, dried orange peel, panax notoginseng, eupatorium japonicum, white peony root, caulis polygoni multiflori, lignum millettiae, bupleurum chinense, turmeric root tuber and licorice. The medical combination of the invention can be added to common pharmaceutical auxiliary materials according to conventional technique to be made into dosage forms that are clinically acceptable. The medical combination of the invention has the functions of activating blood circulation to dissipate blood stasis, reducing swelling and easing pain, removing toxicity and resolving putrid, promoting granulation and wound healing, transforming solids and dispelling nodes and eliminating stasis to activate blood circulation and generate new tissues.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly relate to a kind of pharmaceutical composition and preparation method for the treatment of cervical spondylosis, lumbar spondylosis and traumatic injury.
Background technology
No matter neck, lumbar disc disease are spraining or the strain that accumulation property external force causes of direct violence or indirect violence formation, and the traditional Chinese medical science is referred to as " arthromyodynia ".How by wind and cold invasion and attack, traumatic injury, coagulation of QI-blood, caused by liver and kidney deficiency and cause.Aspect Therapeutic Method, external treatment is better than treatment by oral administration of medicines with treatment by oral administration of medicines.The treatment by oral administration of medicines medicine often suffers from other internal diseases because of the wounded, be subjected to certain limitation during medication, especially to the body of old children weakness, attack and mend in difficulty executes, or when meeting " people that be unwilling to take medicine ", the external treatment with Chinese medicine therapy is not retrained by this then, and reach the same goal by different routes, play the same tune on different musical instruments wonderful arranged with interior oral administration, and interior oral administration plurality of advantages is can't be obtained more arranged.Patch just arises at the historic moment thus, and flourishing long time.
Traumatic injury belongs to the commonly encountered diseases in a kind of daily life, and its sickness rate is only second to flu.People run into beyond thought various wound through regular meeting, as wound, get injured by a fall in life and work, and the lighter injures epidermis, articular sprain and causes that stasis of blood resistance swells and ache, and the weight person fracture disability that disables caused HD to society, and severe patient is deadly.Particularly be engaged in heavy industry labourer, driver and other high-risk labourers.
Though at the medicine of the existing many treatment traumatic injury of orthopaedics hospital among the people and professional, certain curative effect is arranged at present to curing diseases such as sclerotin injury and inside and outside tissue injury.But up to now, the medicine of existing treatment traumatic injury, in quickly alleviating pain hemostasis with to accelerate bone tissue growth this effect aspect two that heals not fairly obvious, general bone injury patient takes one month at least at professional orthopaedics hospital hospitalization, at most more than 1 year, and the medical expense height.
Summary of the invention
The object of the invention is to provide a kind of pharmaceutical composition for the treatment of cervical spondylosis, lumbar spondylosis and traumatic injury.
Another object of the present invention is to provide a kind of preparation of drug combination method and new purposes.
The present invention is achieved through the following technical solutions: choose crude drug
Radix Angelicae Sinensis 5-50 weight portion Olibanum 5-50 weight portion Myrrha 5-50 weight portion
Rhizoma Chuanxiong 5-50 weight portion Radix Angelicae Dahuricae 5-50 weight portion Herba Leonuri 5-50 weight portion
Fructus Aurantii 5-50 weight portion Cortex Cinnamomi 5-50 weight portion Cortex Acanthopancis 5-50 weight portion
Radix Sophorae Flavescentis 5-50 weight portion Herba Schizonepetae 5-50 weight portion Cortex cercis chinensis 5-50 weight portion
Radix Saposhnikoviae 5-50 weight portion Pericarpium Citri Reticulatae 5-50 weight portion Radix Notoginseng 5-50 weight portion
Herba Lycopi 5-50 weight portion Radix Paeoniae Alba 5-50 weight portion Caulis Polygoni Multiflori 5-50 weight portion
Caulis Spatholobi 5-50 weight portion Radix Bupleuri 5-50 weight portion Radix Curcumae 5-50 weight portion
Radix Glycyrrhizae 5-50 weight portion;
The optimum ratio of pharmaceutical composition of the present invention is: choose crude drug
Radix Angelicae Sinensis 30 weight portion Olibanums 30 weight portion Myrrhas 30 weight portions
The Rhizoma Chuanxiong 30 weight portion Radixs Angelicae Dahuricae 30 weight portion Herba Leonuris 30 weight portions
Fructus Aurantii 30 weight portion Cortex Cinnamomi 30 weight portion Cortex Acanthopanciss 30 weight portions
Radix Sophorae Flavescentis 30 weight portion Herba Schizonepetae 30 weight portion Cortex cercis chinensiss 30 weight portions
Radix Saposhnikoviae 30 weight portion Pericarpium Citri Reticulataes 30 weight portion Radix Notoginseng 30 weight portions
The Herba Lycopi 30 weight portion Radix Paeoniae Albas 30 weight portion Caulis Polygoni Multiflori 30 weight portions
Caulis Spatholobi 30 weight portion Radix Bupleuri 30 weight portion Radix Curcumaes 30 weight portions
Radix Glycyrrhizae 30 weight portions;
The optimum ratio of pharmaceutical composition of the present invention is: choose crude drug
Radix Angelicae Sinensis 8 weight portion Olibanums 42 weight portion Myrrhas 10 weight portions
The Rhizoma Chuanxiong 40 weight portion Radixs Angelicae Dahuricae 8 weight portion Herba Leonuris 42 weight portions
Fructus Aurantii 10 weight portion Cortex Cinnamomi 40 weight portion Cortex Acanthopanciss 8 weight portions
Radix Sophorae Flavescentis 42 weight portion Herba Schizonepetae 10 weight portion Cortex cercis chinensiss 40 weight portions
Radix Saposhnikoviae 8 weight portion Pericarpium Citri Reticulataes 42 weight portion Radix Notoginseng 10 weight portions
The Herba Lycopi 40 weight portion Radix Paeoniae Albas 8 weight portion Caulis Polygoni Multiflori 42 weight portions
Caulis Spatholobi 10 weight portion Radix Bupleuri 40 weight portion Radix Curcumaes 8 weight portions
Radix Glycyrrhizae 42 weight portions;
The optimum ratio of pharmaceutical composition of the present invention is: choose crude drug
Radix Angelicae Sinensis 42 weight portion Olibanums 8 weight portion Myrrhas 40 weight portions
The Rhizoma Chuanxiong 10 weight portion Radixs Angelicae Dahuricae 42 weight portion Herba Leonuris 8 weight portions
Fructus Aurantii 40 weight portion Cortex Cinnamomi 10 weight portion Cortex Acanthopanciss 42 weight portions
Radix Sophorae Flavescentis 8 weight portion Herba Schizonepetae 40 weight portion Cortex cercis chinensiss 10 weight portions
Radix Saposhnikoviae 42 weight portion Pericarpium Citri Reticulataes 8 weight portion Radix Notoginseng 40 weight portions
The Herba Lycopi 10 weight portion Radix Paeoniae Albas 42 weight portion Caulis Polygoni Multiflori 8 weight portions
Caulis Spatholobi 40 weight portion Radix Bupleuri 40 weight portion Radix Curcumaes 8 weight portions
Radix Glycyrrhizae 42 weight portions.
Pharmaceutical composition of the present invention is made clinical acceptable exterior-applied formulation according to the conventional adjuvant that common process adds pharmaceutically, as emplastrum, red unguentum, black unguentum, spray, ointment or ointment.
Pharmaceutical composition of the present invention has blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, put forward the effect that poisons corruption, promoting tissue regeneration and ulcer healing, the hard eliminating stagnation of commentaries on classics, dissipating blood stasis tissue regeneration promoting, and is remarkable to treatment traumatic injury, cervical spondylosis, lumbar spondylosis effect.
Following experimental example is used to further specify but is not limited to the present invention:
Tai Fuchun plaster treatment traumatic injury of the present invention, cervical spondylosis, lumbar spondylosis 100 routine clinical observations
One, physical data
100 routine patients all are the outpatient.Wherein male 56 examples, women 44 examples; The oldest 68 years old, minimum 20 years old; The course of disease had 10 examples in the longest 17 years, and 2 examples were arranged in the shortest 3 days; The traumatic injury disease has 30 examples, and cervical spondylosis, lumbar spondylosis have 70 examples.
Two, diagnostic criteria
Film making is made a definite diagnosis through hospital.
Three, criterion of therapeutical effect
Produce effects: symptoms such as pain disappear substantially, and it is normal that functional activity recovers substantially;
Effectively: pain relief, functional activity improves;
Invalid: pain, functional activity obstacle no change before and after the treatment.
Four, Therapeutic Method
Medicine is formed: Radix Angelicae Sinensis, Olibanum, Myrrha, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Herba Leonuri, Fructus Aurantii, Cortex Cinnamomi, Cortex Acanthopancis, Radix Sophorae Flavescentis, Herba Schizonepetae, Cortex cercis chinensis, Radix Saposhnikoviae, Pericarpium Citri Reticulatae, Radix Notoginseng, Herba Lycopi, the Radix Paeoniae Alba, Caulis Polygoni Multiflori, Caulis Spatholobi, Radix Bupleuri, Radix Curcumae, each 5-30 gram of Radix Glycyrrhizae.
Preparation method: Tai Fuchun plaster of the present invention is made emplastrum according to the conventional adjuvant that common process adds pharmaceutically.Using method: external application.
Five, therapeutic outcome
30 examples of traumatic injury, produce effects 20 examples, effective 10 examples, invalid 0 example;
70 examples of cervical spondylosis, lumbar spondylosis, produce effects 58 examples, effective 12 examples, invalid 0 example;
To sum up, medicine composite for curing traumatic injury of the present invention and cervical spondylosis, lumbar spondylosis be totally 100 examples, produce effects 78 examples, effective 22 examples, invalid 0 example.Obvious effective rate is 78%, and effective percentage is 22%.Total effective rate 100%.
Six, model case
Example 1: the Wang, the man, 45 years old, the peasant, careless right lower limb fell in the middle of train and the platform when railway is done the loader in 1997, and knee joint intensity is sprained, and whole left lower limb knee joint is swollen with slowly, and can't walk.The doctor makes a definite diagnosis the knee joint periosteum injury through hospital, uses Tai Fuchun plaster of the present invention, recovery from illness after 10 days.
Example 2: the Meng, the man, 20 years old, the student, 1999 when playing basketball in school, after accidentally left lower limb neck being sprained, have that left lower limb neck is swollen slowly always more than 2 years, after ligament injury is made a definite diagnosis by hospital, use ointment of the present invention, recovery from illness after 10 days.
Example 3: Song, woman, 68 years old, retired cadre, 2002 7 days, old man's 2 joint vertebras in lumbar vertebra is fallen in toilet accidentally erect looked into fracture, and old man's pain is moaned and can not be fallen asleep in three days unbearably, lower limb can not be walked, and use pain relieving on the same day behind the Tai Fuchun plaster of the present invention, recovery from illness on the 10th.
Example 4: Xu certain, the woman, 62 years old, the peasant, 1998, Xu certain at the rural area family, see that weather will rain, with Polypropylence Sheet lid bavin buttress, fall accidentally, old man's lower part of the body was inactive at that time, after joint fracture in the lumbar vertebra is made a definite diagnosis by hospital, needed long-time hospitalization.The old man is limited because of household economy, is in hospital after 15 days, and the household takes back house to the old man and takes medicine and recuperate, and has have a surplus nearly January and fails to get up, and through using black plaster of the present invention after 10 days, the old man can sit up, used 20 days again after, just can walk with descending.
Example 5: the week certain, the woman, 51 years old, the rail man, 95 years since cervical spondylosis cause the headache numbness of hand, with plaster 3-7 of the present invention days the recovery from illness, so far the recurrence.
Example 6: in certain, the woman, 49 years old, 1999 for many years pain in the lumbar region can not do farm work, she goes to hospital to be diagnosed as prolapse of lumbar intervertebral disc herself.With recovery from illness in spray 7-10 of the present invention days, can do various farm work so far, do not have recurrence again.
Following embodiment is used to further specify the present invention:
The specific embodiment
Embodiment 1:
Radix Angelicae Sinensis 30kg Olibanum 30kg Myrrha 30kg
Rhizoma Chuanxiong 30kg Radix Angelicae Dahuricae 30kg Herba Leonuri 30kg
Fructus Aurantii 30kg Cortex Cinnamomi 30kg Cortex Acanthopancis 30kg
Radix Sophorae Flavescentis 30kg Herba Schizonepetae 30kg Cortex cercis chinensis 30kg
Radix Saposhnikoviae 30kg Pericarpium Citri Reticulatae 30kg Radix Notoginseng 30kg
Herba Lycopi 30kg Radix Paeoniae Alba 30kg Caulis Polygoni Multiflori 30kg
Caulis Spatholobi 30kg Radix Bupleuri 30kg Radix Curcumae 30kg
Radix Glycyrrhizae 30kg;
Get the above-mentioned raw materials medicine and make the Tai Fuchun plaster according to the conventional adjuvant that common process adds pharmaceutically.
Embodiment 2:
Radix Angelicae Sinensis 8kg Olibanum 42kg Myrrha 10kg
Rhizoma Chuanxiong 40kg Radix Angelicae Dahuricae 8kg Herba Leonuri 42kg
Fructus Aurantii 10kg Cortex Cinnamomi 40kg Cortex Acanthopancis 8kg
Radix Sophorae Flavescentis 42kg Herba Schizonepetae 10kg Cortex cercis chinensis 40kg
Radix Saposhnikoviae 8kg Pericarpium Citri Reticulatae 42kg Radix Notoginseng 10kg
Herba Lycopi 40kg Radix Paeoniae Alba 8kg Caulis Polygoni Multiflori 42kg
Caulis Spatholobi 10kg Radix Bupleuri 40kg Radix Curcumae 8kg
Radix Glycyrrhizae 42kg;
The above-mentioned raw materials medicine is made red unguentum according to the conventional adjuvant that common process adds pharmaceutically.
Embodiment 3:
Radix Angelicae Sinensis 42kg Olibanum 8kg Myrrha 40kg
Rhizoma Chuanxiong 10kg Radix Angelicae Dahuricae 42kg Herba Leonuri 8kg
Fructus Aurantii 40kg Cortex Cinnamomi 10kg Cortex Acanthopancis 42kg
Radix Sophorae Flavescentis 8kg Herba Schizonepetae 40kg Cortex cercis chinensis 10kg
Radix Saposhnikoviae 42kg Pericarpium Citri Reticulatae 8kg Radix Notoginseng 40kg
Herba Lycopi 10kg Radix Paeoniae Alba 42kg Caulis Polygoni Multiflori 8kg
Caulis Spatholobi 40kg Radix Bupleuri 40kg Radix Curcumae 8kg
Radix Glycyrrhizae 42kg.
Get the above-mentioned raw materials medicine, make black unguentum according to the conventional adjuvant that common process adds pharmaceutically.
Embodiment 4:
Radix Angelicae Sinensis 30kg Olibanum 30kg Myrrha 30kg
Rhizoma Chuanxiong 30kg Radix Angelicae Dahuricae 30kg Herba Leonuri 30kg
Fructus Aurantii 30kg Cortex Cinnamomi 30kg Cortex Acanthopancis 30kg
Radix Sophorae Flavescentis 30kg Herba Schizonepetae 30kg Cortex cercis chinensis 30kg
Radix Saposhnikoviae 30kg Pericarpium Citri Reticulatae 30kg Radix Notoginseng 30kg
Herba Lycopi 30kg Radix Paeoniae Alba 30kg Caulis Polygoni Multiflori 30kg
Caulis Spatholobi 30kg Radix Bupleuri 30kg Radix Curcumae 30kg
Radix Glycyrrhizae 30kg;
Get the above-mentioned raw materials medicine, make spray according to the conventional adjuvant that common process adds pharmaceutically.
Embodiment 5:
Radix Angelicae Sinensis 30kg Olibanum 30kg Myrrha 30kg
Rhizoma Chuanxiong 30kg Radix Angelicae Dahuricae 30kg Herba Leonuri 30kg
Fructus Aurantii 30kg Cortex Cinnamomi 30kg Cortex Acanthopancis 30kg
Radix Sophorae Flavescentis 30kg Herba Schizonepetae 30kg Cortex cercis chinensis 30kg
Radix Saposhnikoviae 30kg Pericarpium Citri Reticulatae 30kg Radix Notoginseng 30kg
Herba Lycopi 30kg Radix Paeoniae Alba 30kg Caulis Polygoni Multiflori 30kg
Caulis Spatholobi 30kg Radix Bupleuri 30kg Radix Curcumae 30kg
Radix Glycyrrhizae 30kg;
Get the above-mentioned raw materials medicine and make ointment according to the conventional adjuvant that common process adds pharmaceutically.
Embodiment 6:
Radix Angelicae Sinensis 30kg Olibanum 30kg Myrrha 30kg
Rhizoma Chuanxiong 30kg Radix Angelicae Dahuricae 30kg Herba Leonuri 30kg
Fructus Aurantii 30kg Cortex Cinnamomi 30kg Cortex Acanthopancis 30kg
Radix Sophorae Flavescentis 30kg Herba Schizonepetae 30kg Cortex cercis chinensis 30kg
Radix Saposhnikoviae 30kg Pericarpium Citri Reticulatae 30kg Radix Notoginseng 30kg
Herba Lycopi 30kg Radix Paeoniae Alba 30kg Caulis Polygoni Multiflori 30kg
Caulis Spatholobi 30kg Radix Bupleuri 30kg Radix Curcumae 30kg
Radix Glycyrrhizae 30kg;
Get the above-mentioned raw materials medicine and make ointment according to the conventional adjuvant that common process adds pharmaceutically.
Claims (7)
1. pharmaceutical composition for the treatment of cervical spondylosis, lumbar spondylosis and traumatic injury, its feature exists
Crude drug in this pharmaceutical composition consists of:
Radix Angelicae Sinensis 5-30 weight portion Olibanum 5-30 weight portion Myrrha 5-30 weight portion
Rhizoma Chuanxiong 5-30 weight portion Radix Angelicae Dahuricae 5-30 weight portion Herba Leonuri 5-30 weight portion
Fructus Aurantii 5-30 weight portion Cortex Cinnamomi 5-30 weight portion Cortex Acanthopancis 5-30 weight portion
Radix Sophorae Flavescentis 5-30 weight portion Herba Schizonepetae 5-30 weight portion Cortex cercis chinensis 5-30 weight portion
Radix Saposhnikoviae 5-30 weight portion Pericarpium Citri Reticulatae 5-30 weight portion Radix Notoginseng 5-30 weight portion
Herba Lycopi 5-30 weight portion Radix Paeoniae Alba 5-30 weight portion Caulis Polygoni Multiflori 5-30 weight portion
Caulis Spatholobi 5-30 weight portion Radix Bupleuri 5-30 weight portion Radix Curcumae 5-30 weight portion
Radix Glycyrrhizae 5-30 weight portion.
2. pharmaceutical composition as claimed in claim 1 is characterized in that the crude drug of this pharmaceutical composition consists of:
Radix Angelicae Sinensis 8 weight portion Olibanums 42 weight portion Myrrhas 10 weight portions
The Rhizoma Chuanxiong 40 weight portion Radixs Angelicae Dahuricae 8 weight portion Herba Leonuris 42 weight portions
Fructus Aurantii 10 weight portion Cortex Cinnamomi 40 weight portion Cortex Acanthopanciss 8 weight portions
Radix Sophorae Flavescentis 42 weight portion Herba Schizonepetae 10 weight portion Cortex cercis chinensiss 40 weight portions
Radix Saposhnikoviae 8 weight portion Pericarpium Citri Reticulataes 42 weight portion Radix Notoginseng 10 weight portions
The Herba Lycopi 40 weight portion Radix Paeoniae Albas 8 weight portion Caulis Polygoni Multiflori 42 weight portions
Caulis Spatholobi 10 weight portion Radix Bupleuri 40 weight portion Radix Curcumaes 8 weight portions
Radix Glycyrrhizae 42 weight portions.
3. pharmaceutical composition as claimed in claim 1 is characterized in that the crude drug of this pharmaceutical composition consists of:
Radix Angelicae Sinensis 42 weight portion Olibanums 8 weight portion Myrrhas 40 weight portions
The Rhizoma Chuanxiong 10 weight portion Radixs Angelicae Dahuricae 42 weight portion Herba Leonuris 8 weight portions
Fructus Aurantii 40 weight portion Cortex Cinnamomi 10 weight portion Cortex Acanthopanciss 42 weight portions
Radix Sophorae Flavescentis 8 weight portion Herba Schizonepetae 40 weight portion Cortex cercis chinensiss 10 weight portions
Radix Saposhnikoviae 42 weight portion Pericarpium Citri Reticulataes 8 weight portion Radix Notoginseng 40 weight portions
The Herba Lycopi 10 weight portion Radix Paeoniae Albas 42 weight portion Caulis Polygoni Multiflori 8 weight portions
Caulis Spatholobi 40 weight portion Radix Bupleuri 40 weight portion Radix Curcumaes 8 weight portions
Radix Glycyrrhizae 42 weight portions.
4. as claim 1,2 or 3 arbitrary described pharmaceutical compositions, it is characterized in that this pharmaceutical composition makes the dosage form of clinical acceptance according to the conventional adjuvant that common process adds pharmaceutically.
5. pharmaceutical composition as claimed in claim 4 is characterized in that described dosage form is: black unguentum, spray, ointment or ointment.
6. pharmaceutical composition as claimed in claim 4 is characterized in that described dosage form is an emplastrum.
7. as claim 1, the application of 2 or 3 arbitrary described pharmaceutical compositions in the medicine of preparation treatment cervical spondylosis, lumbar spondylosis and traumatic injury.
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CN2008101145604A CN101279080B (en) | 2008-06-04 | 2008-06-04 | Medicament composition for curing cervical vertebra disease, lumbar disease and traumatic injury and preparation method |
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CN2008101145604A CN101279080B (en) | 2008-06-04 | 2008-06-04 | Medicament composition for curing cervical vertebra disease, lumbar disease and traumatic injury and preparation method |
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CN101279080B true CN101279080B (en) | 2010-12-15 |
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Families Citing this family (3)
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CN101721672B (en) * | 2010-01-13 | 2011-07-20 | 郑廷佩 | Medicine for treating rheumatic numbness and pain |
CN102302564B (en) * | 2011-09-15 | 2013-09-18 | 上海交通大学医学院附属新华医院 | Pain stasis and paralysis eliminating powder for treating soft tissue injury |
CN103446509B (en) * | 2013-08-01 | 2015-11-25 | 焦敏 | A kind of Chinese medicine for the treatment of soft tissue injury |
Citations (2)
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CN1297770A (en) * | 1999-11-30 | 2001-06-06 | 许鸿起 | Meridian passage dredging and pain relieving medicated liquor |
CN1363364A (en) * | 2001-12-28 | 2002-08-14 | 吕春荣 | Chinese medicine for treating lumbar intervertebral disk protrusion |
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2008
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Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1297770A (en) * | 1999-11-30 | 2001-06-06 | 许鸿起 | Meridian passage dredging and pain relieving medicated liquor |
CN1363364A (en) * | 2001-12-28 | 2002-08-14 | 吕春荣 | Chinese medicine for treating lumbar intervertebral disk protrusion |
Non-Patent Citations (2)
Title |
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