CN1161147C - Oral Chinese medicine for curing osteoarthropathy - Google Patents

Oral Chinese medicine for curing osteoarthropathy Download PDF

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Publication number
CN1161147C
CN1161147C CNB021324379A CN02132437A CN1161147C CN 1161147 C CN1161147 C CN 1161147C CN B021324379 A CNB021324379 A CN B021324379A CN 02132437 A CN02132437 A CN 02132437A CN 1161147 C CN1161147 C CN 1161147C
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radix
root
medicine
rhizoma
chinese medicine
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CNB021324379A
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CN1400007A (en
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郭好建
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郭好建
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Abstract

The present invention relates to oral traditional Chinese medicine for treating acute and chronic osteoarthritis, which belongs to a Chinese materia medica preparation. The medicine is prepared from notopterygium root, pubescent angelica root, turmeric, angelica, red peony, astragalus root, pilose asiabell root, ledebouriella root, ephedra herb, cassia twig, scorpion, earthworm, tuckahoe, coix seed, clematis root, corydalis tuber, frankincense, myrrh, eupolyphage sinensis, safflower, peach seed, hemlock parsley, rhizoma drynariae, himalayan teasel root, medicinal cyathula root, notoginseng, manchurian wildginger, common monkshood daughter root, pawpaw, eucommia bark, Chinese taxillus twig, east Asian tree fern rhizome and suberect spatholobus stem. The raw materials are mixed and crushed to prepare the medicine; the formulation is scientific, and the theory of treatment on the basis of differentiation of symptoms and signs is used. The medicine has the effects of warming channels, dispelling cold, removing moisture, promoting blood circulation, removing blood stasis, dredging channels, nourishing Qi and blood, relieving rigidity of muscles and joints, and alleviating pain; the medicine cures 620 patients with acute and chronic rheumatoid arthritis, and the curative effect is conspicuous.

Description

A kind of oral Chinese medicine for the treatment of joint disease
Affiliated technical field
The invention belongs to Chinese medicine preparation, particularly a kind of oral Chinese medicine for the treatment of the acute and chronic joint disease.
Background technology
Osteoarthritis is common clinical, frequently-occurring disease.The pathological changes that osteoarthrosis is got involved is a lot, as: deviate between acute and chronic rheumatoid arthritis, osteoarthritis, lumbar vertebra, pathological changes such as bulging, scapulohumeral periarthritis, cervical spondylosis, femur head necrosis, these diseases have the relapse rate height, are difficult for the radical cure characteristics.Pressuring nerve, amyotrophy, pathological dislocation of joint, symptom such as tetanic can appear with PD, find in diagnosis and treatment patient disease process, as adopt therapies such as acupuncture, electrotherapy, traction, the patient light to disease, that medical history is short has certain curative effect, but, and easily recurrence not good enough to patient's curative effect that disease is heavier.The patient who also has adopts the clinical non-hormone anti-inflammatory agent commonly used treatment of doctor trained in Western medicine, as medicines such as indometacin, diclofenac, ibuprofen, these medical instruments have rapid-action, good analgesic effect, be prone to many side effect but take for a long time, as anaphylaxis, gastrointestinal symptom, anemia, hepatic and renal function injure etc., also have some patients with severe symptoms to adopt the hormones anti-inflammatory drug, as meticorten, medicines such as dexamethasone though this medicine can play the anti-inflammatory analgetic effect, can not effect a radical cure and can not suppress PD, and the drug withdrawal difficulty, it is more to take side effect for a long time.As: gastrointestinal symptom, central obesity, nervous, hypertension, osteoporosis, aseptic osteonecrosis etc., take Chinese patent medicine or Chinese and Western medicine mixture, the curative effect instability can not be eliminated condition of illness, eliminates painful.
Summary of the invention
The present invention is by the natural plant kind medicine, the insects medicine is formed, and prescription is as follows: Rhizoma Et Radix Notopterygii 15-25 part, Radix Angelicae Pubescentis 15-25 part, Rhizoma Curcumae Longae 10-20 part, Radix Angelicae Sinensis 15-20 part, Radix Paeoniae Rubra 10-15 part, Radix Astragali 10-20 part, Radix Codonopsis 20-30 part, Radix Saposhnikoviae 15-25 part, Herba Ephedrae 10-15 part, Ramulus Cinnamomi 10-25 part, Scorpio 10-20 part, Pheretima 10-20 part, Poria 15-25 part, Semen Coicis 15-25 part, Radix Clematidis 10-20 part, Rhizoma Corydalis 15-25 part, Olibanum 10-20 part, Myrrha 10-20 part, Eupolyphaga Seu Steleophaga 15-25 part, Flos Carthami 10-20 part, Semen Persicae 10-15 part, Rhizoma Chuanxiong 15-25 part, Rhizoma Drynariae 10-20 part, Radix Dipsaci 15-20 part, Radix Cyathulae 15-20 part, Radix Notoginseng 10-15 part, Herba Asari 5-10 part, Radix Aconiti Lateralis Preparata 10-15 part, Fructus Chaenomelis 15-20 part, Cortex Eucommiae 10-20 part, Herba Taxilli 15-20 part, Rhizoma Cibotii 10-20 part, Caulis Spatholobi 10-20 part.
We's drug anesthesia Huang, Ramulus Cinnamomi, Radix Saposhnikoviae, Rhizoma Et Radix Notopterygii, Herba Asari drug matching have good hot temperature disperse function, and then the expelling wind and removing dampness effect is remarkable for Radix Angelicae Pubescentis, Radix Clematidis, Fructus Chaenomelis, Herba Taxilli compatibility, and Poria, Semen Coicis compatibility are that mutual reinforcement between is with energy diuretic spleen invigorating eliminating dampness by diuresis; Herba Asari in Radix Aconiti Lateralis Preparata and the medicine-feeding is joined then can strengthen the expelling pathogenic cold by warming the meridian effect.Above-mentioned all medicines organically combine plays expelling wind and cold altogether except that warm effect, is monarch drug.Make that the osteoarticular enlargement hydrops of pathological changes, happiness are warm is afraid of cool acid precipitation symptom, the synergism by above-mentioned all medicines excites yang-energy, regulates space between skin and muscles hair key, the folding of kidney key, the removing cold and wind three kinds of pathogens that wet.Modern pharmacological research, Ramulus Cinnamomi, the contained volatile oil energy of Rhizoma Et Radix Notopterygii blood vessel dilating, adjustment blood circulation, having additional nutrients property blood flow is beneficial to the heat radiation diaphoresis; The contained terpineol of Herba Ephedrae has analgesic perspiration.The contained aconite alkaloid of Radix Aconiti Lateralis Preparata has good analgesic activity; Ascorbic acid contained in the Fructus Chaenomelis has the detumescence effect to arthritis, and Radix Saposhnikoviae, Herba Asari, Radix Angelicae Pubescentis, the contained effective ingredient of Radix Clematidis have significant analgesic and anti-inflammatory effects.Obvious to arthritis, lumbago and skelalgia, neuralgia effect.Rhizoma Chuanxiong, Semen Persicae, Flos Carthami, Olibanum, Myrrha, Radix Cyathulae, Rhizoma Corydalis, Rhizoma Curcumae Longae, Eupolyphaga Seu Steleophaga, Radix Notoginseng, Radix Paeoniae Rubra in this prescription, compatibility has the effect of blood circulation promoting and blood stasis dispelling, is ministerial drug.Modern pharmacological research proof ligustrazine can be expanded peripheral blood vessel, and chronic microcirculation disturbance is improved significantly; The ethanol extract energy blood vessel dilating of Semen Persicae, suppress blood coagulation, Flos Carthami energy anticoagulant, fortifying fibre, protein dissolution, Radix Notoginseng have good anastalsis, and the total Saponin energy of Radix Notoginseng anticoagulant, has sedation, can also regulate too high or too low immunoreation, but not disturb normal immunoreation, the Saponin in the Radix Cyathulae has the dominance of promotion swelling regressive effect to arthritis; The stronger analgesic activity of Rhizoma Corydalis element tool in the Rhizoma Corydalis, and Radix Paeoniae Rubra, Olibanum, the contained effective ingredient of Myrrha all have good anti-inflammatory, repercussive and analgesic effect.Radix Angelicae Sinensis, Caulis Spatholobi, Radix Codonopsis, Radix Astragali compatibility have the effect of vigorate qi and replenish the blood in the medicine of the present invention, be adjuvant drug altogether, they can regulate modern pharmacological research or enhancing body's immunological function, and the Cortex Eucommiae, Rhizoma Cibotii, Rhizoma Drynariae, Radix Dipsaci compatibility have the effect of tonifying liver and kidney and strengthening bones and muscles.Insect medicine has the property of the string of walking, Pheretima, Scorpio compatibility energy promoting blood circulation to remove obstruction in the collateral, draw the effect at the through sick place of all medicines, the justice of traction warp is messenger drug altogether, assist monarch drug, ministerial drug performance curative effect, all medicine compatibilities not only can suppress immunoinflammatory reaction, and a lot of medicines are all gone into Liver and kidney two through with the endocrine regulation function, and theory of Chinese medical science is thought liver governing tendons, kidney governing bones, can make a variety of causes cause fibrinolysis with Chinese medicine of the present invention, remove free radical, play inhibition synovium of joint hypertrophy and blood vessel and be split into, stop sclerotin to be attacked, improve the blood circulation in pathological changes joint, repair disrupted sclerotin, drug for invigorating blood circulation and eliminating stasis and collateral dredging medicine compatibility can play good relaxing muscles and tendons and activating QI and blood in the collateral effect, and calcification or the curved articular ligament that contracts are recovered, prevent pathological dislocation of joint, fibrous ankylosis or bony ankylosis.The application strengthening the body resistance of benefiting QI and nourishing blood medicine, the human body immunity improving ability makes after the prolonged illness, and the weak symptom of the deficiency of vital energy is restored.
The specific embodiment
A kind of oral Chinese medicine for the treatment of joint disease is made up of following Chinese medicine: Rhizoma Et Radix Notopterygii 15-25g, Radix Angelicae Pubescentis 15-25g, Rhizoma Curcumae Longae 10-20g, Radix Angelicae Sinensis 15-20g, Radix Paeoniae Rubra 10-15g, Radix Astragali 10-20g, Radix Codonopsis 20-30g, Radix Saposhnikoviae 15-25g, Herba Ephedrae 10-15g, Ramulus Cinnamomi 10-25g, Scorpio 10-20g, Pheretima 10-20g, Poria 15-25g, Semen Coicis 15-25g, Radix Clematidis 10-20g, Rhizoma Corydalis 15-25g, Olibanum 10-20g, Myrrha 10-20g, Eupolyphaga Seu Steleophaga 15-25g, Flos Carthami 10-20g, Semen Persicae 10-15g, Rhizoma Chuanxiong 15-25g, Rhizoma Drynariae 10-20g, Radix Dipsaci 15-20g, Radix Cyathulae 15-20g, Radix Notoginseng 10-15g, Herba Asari 5-10g, Radix Aconiti Lateralis Preparata 10-15g, Fructus Chaenomelis 15-20g, Cortex Eucommiae 10-20g, Herba Taxilli 15-20g, Rhizoma Cibotii 10-20g, Caulis Spatholobi 10-20g.
With above-mentioned medicine uniform mixing, pulverize the back and cross square-bottomed bamboo basket, incapsulating can be standby, every day oral secondary or three times, each five, 7 days is an auxiliary medicine.
The effect of medicine of the present invention is the dispelling cold by warming the meridian dehumidifying, activating blood circulation to dissipate blood stasis and dredge the collateral, benefiting QI and nourishing blood, relieving rigidity of muscles and joints pain relieving.Medicine of the present invention not only curative effect is quick, and long-term use without side effects, but can not be used for hot disease, Chinese medicine focuses on and effects a permanent cure, and the patient of osteoarthritis is arranged, through using this Drug therapy, not only disorder of joint is healed entirely, and the General Symptoms of following disappearance, makes the thorough rehabilitation of patient, as suffers from rheumatism, rheumatoid patient, not only attack the joint with PD, also with weak lossless or spontaneous perspiration, lassitude, the warm fearness of health happiness is cool, be off one's feed, uncomfortable in chest, xerostomia is not thirsty, loose stool, play each joint in night or morning and knit tightly the symptom that is weighing whole body underactivity such as stiff, through with after the treatment by Chinese herbs of the present invention, the General Symptoms of following can be alleviated gradually, up to thorough rehabilitation, can be widely used in osteoarthritis in clinical, cold-damp.
Oral Chinese medicine stable curative effect of the present invention, long-term use without side effects has the healing curative effect to various osteoarthrosis.The osteoarthritis patient that some external treatment are not healed is by treating the work of having walked, all there is not recurrence after several years, cure patient's age from adolescence to octogenarian old people, medical history does not wait from several years to three more than ten years, treatment time is 2 courses of treatment, and wherein patient's majority of dominant rheumatoid arthritis has been in the fibrous ankylosis stage.By statistics, cure acute and chronic rheumatoid arthritis 620 examples altogether, wherein bony ankylosis 2 examples, cold-damp arthritis 160 examples, osteoarthritis 108 examples, lumbar intervertebral disc is deviate from, bulging patient 80 examples, cervical spondylosis, cervical-shoulder syndrome 94 examples, scapulohumeral periarthritis 40 examples, femur head necrosis 2 examples, scorching 72 examples of peripheral nerve, sciatica 50 examples, heel osteodynia 10 examples, soft tissue injury 34 examples.
Case 1: white XX, the man, 85 years old, cold is ached, is afraid of to nearly 2 years cervical vertebras of this patient's self-induction, movable unfavorable, and increase the weight of gradually, the companion is dizzy, hand thumb, forefinger, middle finger numbness.X-ray film shows: cervical vertebra degenerative change, spinal canal stenosis, C 4-5, C 5-6, C 6-7Disc calcification.Be diagnosed as cervical spondylosis.This patient's extract oral treated for 4 weeks, and the disappearance of all diseases is fully recovered.
Case 2: Liu XX, the woman, 46 years old, this patient's cervical vertebra, right shoulder arm pain were afraid of that cool happiness is warm, movable unfavorable 1 month.X-ray film shows: cervical vertebra 5,6 internode cracks narrow down, the right side is work, curvature is reverse, pain increased the weight of when readme was carried weight or right arm and let droop, once took therapies such as Chinese medicine and western medicine, acupuncture-moxibustion, traction, slightly alleviate, but stop to treat still pain, look into: 5th, 6 cervical vertebras and right shoulder joint, the inside and outside side pressure pain of forearm (+).This patient oral treatment altogether for 4 weeks that take traditional Chinese medicine, every day three times, recovery from illness can be participated in work.
Case 3: Lee XX, man, 77 years old, pain appears in the left the year before knee joint of this patient's readme, and movable unfavorable, all diseases are increased the weight of during walking, felt the left hip arthralgia in nearly two months, movable unfavorable, the left lower extremity pain that lands increases the weight of, lie on the left side press nearly left hip joint can the time sharp ache, turn support by post during walking, through the hospitalize of several families with buy medicine and take and all do not have positive effect, look into when examining, lower edge tenderness (+) on ectocondyle and the patella in left side knee joint is slightly swollen, companion's joint stuffiness, left hip joint tenderness (+).X-ray film shows: left knee joint condyle gap knuckle comes to a point, and lower edge has bony spur to form on the patella, and the fl head is flat, the bone density inequality, and left kneecap joint space narrows down.Take 1 course of treatment of medicine of the present invention, all diseases of left knee joint disappear, and 3 recoveries from illness courses of treatment are treated in left kneecap joint altogether, need not lean on and turn then walking freely.
Case 4: king XX, the woman, 56 years old, this patient's waist was sprained history 3 years, the self-induction soreness of waist bitterly usually, movable unfavorable, companion's right lower extremity numbness, morning at night the time-out sx, through hospital diagnosis is " spinal canal stenosis ", in recent years in the middle of once multi-treatment do not heal, through alleviating with medicine of the present invention oral 1 all diseases, treat altogether 5 the week and fully recover.
Case 5: Lee XX, woman, 44 years old, the right shoulder joint of this patient, omoplate are ached, and are afraid of cold, movable unfavorable 4 years, increase the weight of half a year, when work or chance cold, the pain increased, the warm fearness of companion's whole body happiness is cool, listlessness, the light red tongue tongue is white less, a little less than the deep-thready pulse, t spine ap ﹠ lat shows through X-ray film: thoracic vertebra physiology curvature is instead " s " type, T 5-12Anterior margin of vertebral body all has sclerotin in various degree to become prominent, diagnosis thoracic vertebra degeneration, and thoracic vertebra physiology curvature side is other lopsided, and this patient takes 1 week of medicine of the present invention, transference cure, the conscious mental status is good, and it is cool not have the warm fearness of obviously happiness, can normally work.
Case 6: leaf XX, the woman, 27 years old, these patient's two soles, double knee joint, both hands articulations digitorum manus pain, be afraid of cool, swelling a year and a half, whenever night or all diseases of time-out in morning are increased the weight of, accompany weak, lossless, the warm fearness cold of happiness, listlessness, biped can not be stepped on hard thing during walking, through taking medicine of the present invention, treatment 1 other arthralgia swelling of week is alleviated, and only sole, face pain, swelling are heavier.Medication 3 all arthralgias, swelling are obviously alleviated, and whole body is afraid of cool, are weighing sense and are alleviating, and self-induction food drink is not good, and walking back double knee joint pain is weighing the sense aggravation, poor sleep, and pale tongue with white fur is greasy, treats 7 all diseases altogether and disappears, and can normally work.
Case 7, king XX, the woman, 58 years old, pain after this patient's waist wound was afraid of cold, tetanic 23 years, increases the weight of 2 years.The CT sheet shows L 3/4, L 4/5, L 5/s1Annuler bulge; L 3/4, L 4/5, L 5/s1The intervertebral disc pneumatosis, L 5Vertebral body trailing edge calcification of posterior longitudinal ligament is diagnosed as the degeneration of lumbar intervertebral disc.And accompanied with hypertension, BP100/180mmHg, through taking 7 weeks of treatment by Chinese herbs of the present invention, all disease recoveries from illness can be done chores.
Case 8, Song X, the woman, 55 years old, this patient's self-induction began the frequent pain in each joint of whole body before 10 years, was afraid of cold, enlargement, movable unfavorable, the time heavy when light, aggravate every spring, double knee joint pain in recent years, enlargement, distortion were once taken western medicines in treatment and were not healed.Be diagnosed as the rheumatoid arthritis bony ankylosis, health is afraid of that cool happiness is warm lossless usually, fidgety being off one's feed, xerostomia is not thirsty, urinate light white loose stool, the white thick and greasy fur of light red tongue, floating and moderate pulse moistens, treated for 7 weeks through taking the present invention, right knee joint and whole body simultaneous phenomenon disappear, and left knee joint can be bent and stretched, and pain is afraid of all obviously alleviations of cold, treat all disease disappearances 4 courses of treatment altogether, can walking work is cured.
Case 9, Wu XX, the woman, 60 years old, this patient's rheumatism medical history 30 years, the time heavy when light, the soreness of waist was afraid of cold bitterly in nearly 2 years, tetanic can not bending over; Right arthroncus of knee joints, ache, be afraid of cold, joint stuffiness, all diseases are increased the weight of gradually, the weak lossless poor appetite of self-induction, night, the pain increased and influence rest, and just rare invisible, greasy urine is unfavorable, xerostomia is not thirsty, and the light red tongue thick fur is greasy in vain, a little less than the deep-thready pulse, through take medicine of the present invention treat 1 the course of treatment flank pain, be afraid of cool the alleviation, easily activity, right arthroncus of knee joints hydrops disappears, pain relief, but also feel right condyle nest " muscle is short ", joint stuffiness is treated 3 all disease recoveries from illness course of treatment altogether.
Case 10, high XX, the woman, 56 years old, this patient's diabetic history 2 years was once taken " three types of diabetes ball " medicine blood sugar control, self-induction vola toe numbness the year before, acupuncture sample pain, swelling then, both hands refer to numb pain in recent years, and self-induction swelling can not be clenched fist, and all diseases are increased the weight of night.Accompany weakly, mouthful slightly very thirsty, urine is yellow skin slightly frequently, and there is crackle on the light red tongue limit, and thick fur is slightly yellow, and after taking medicine of the present invention and treating for 1 week, at the bottom of the further consultation biped, both hands swelling alleviates, pain numbness is obviously alleviated, and treats for 3 weeks altogether, and diseases such as pain, numbness, swelling disappear.
Case 11 is opened X, the man, 45 years old, these patient's both hands referred to pain, be afraid of cool, pale, increase the weight of night, disease 10 years, the right hand is heavy than left hand, finger tip diabrosis in the right hand, fingernail thickens distortion, is " peripheral nerve inflammation " through hospital diagnosis, dead point " penicillin " when readme increases the weight of whenever festering, month complementary energy is slightly alleviated, finger tip sharp ache in the right hand when examining is accompanied weak, soreness of waist pain is urinated light white, pale tongue with white fur has crackle, deep and weak pulse is unable, treats for 2 weeks with oral medicinal herb of the present invention, and other finger symptoms are obviously alleviated, right hand middle finger pain alleviates than before, skin is little red no longer pale, and finger tip festers to begin to form a scab and seals, and the skin ulcer face dwindles than before, weak alleviating, waist is not sour, and deep and weak pulse should refer to than before, treats 2 courses of treatment and fully recovers.
Case 12, Lee XX, man, 46 years old, this patient once sprained right hip joint in the middle of work, also for arousing attention, took " SHENYANG HONGYAO " at that time, still adhered to work after the rest, but self-induction pain, movable symptom such as unfavorable increases the weight of gradually, once in other hospitalizes, does not have positive effect.Come my institute's treatment, the X sheet shows: right lateral thigh bone is most of to be lacked, and its inner structure is fuzzy, and density alleviates, and left side hip joint face mould is stuck with paste increase in density, and the hip joint gap disappears, joint dislocation, Shen Tong Shi line, Tong Shi heading line off.Being diagnosed as right side severe femur head necrosis (head lack as) looks into when examining: tenderness (+) companion amyotrophy before and after the right hips.Can not crouch on the right side, can not stand up, support by crutches during walking, the light left lower extremity of self-induction right lower extremity is short, takes Chinese medicine of the present invention, the drug of topical application, the right hips arthralgia of 2 week back self-inductions alleviate, when movable right lower extremity than medication before easily, 10 week of treatment the back pain obviously alleviate, can stand up in bed during rest, when treating six courses of treatment, walking need not be leant on crutches, treat 13 courses of treatment, pain disappears, and walking can be done housework freely.

Claims (1)

1, a kind of oral Chinese medicine for the treatment of joint disease is characterized in that being made up of following Chinese medicine: Rhizoma Et Radix Notopterygii 15-25 part, Radix Angelicae Pubescentis 15-25 part, Rhizoma Curcumae Longae 10-20 part, Radix Angelicae Sinensis 15-20 part, Radix Paeoniae Rubra 10-15 part, Radix Astragali 10-20 part, Radix Codonopsis 20-30 part, Radix Saposhnikoviae 15-25 part, Herba Ephedrae 10-15 part, Ramulus Cinnamomi 10-25, Scorpio 10-20 part, Pheretima 10-20 part, Poria 15-25 part, Semen Coicis 15-25 part, Radix Clematidis 10-20 part, Rhizoma Corydalis 15-25 part, Olibanum 10-20 part, Myrrha 10-20 part, Eupolyphaga Seu Steleophaga 15-25 part, Flos Carthami 10-20 part, Semen Persicae 10-15 part, Rhizoma Chuanxiong 15-25 part, Rhizoma Drynariae 10-20 part, Radix Dipsaci 15-20 part, Radix Cyathulae 15-20 part, Radix Notoginseng 10-15 part, Herba Asari 5-10 part, Radix Aconiti Lateralis Preparata 10-15 part, Fructus Chaenomelis 15-20 part, Cortex Eucommiae 10-20 part, Herba Taxilli 15-20 part, Rhizoma Cibotii 10-20 part, Caulis Spatholobi 10-20 part.
CNB021324379A 2002-06-10 2002-06-10 Oral Chinese medicine for curing osteoarthropathy CN1161147C (en)

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CN106139005A (en) * 2016-08-01 2016-11-23 邓炳章 A kind of Chinese medicine composition treating prolapse of lumbar intervertebral disc

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