CN101232899A - 维持产胰岛素细胞功能的方法 - Google Patents

维持产胰岛素细胞功能的方法 Download PDF

Info

Publication number
CN101232899A
CN101232899A CNA2006800283625A CN200680028362A CN101232899A CN 101232899 A CN101232899 A CN 101232899A CN A2006800283625 A CNA2006800283625 A CN A2006800283625A CN 200680028362 A CN200680028362 A CN 200680028362A CN 101232899 A CN101232899 A CN 101232899A
Authority
CN
China
Prior art keywords
insulin
patient
medicine
purposes
producing cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2006800283625A
Other languages
English (en)
Chinese (zh)
Inventor
安德斯·哈萨格尔·博斯
韦曼·温蒂尔·师特汉姆
戴维·C·戴尔蒙德
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mannkind Corp
Original Assignee
Mannkind Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mannkind Corp filed Critical Mannkind Corp
Publication of CN101232899A publication Critical patent/CN101232899A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CNA2006800283625A 2005-08-01 2006-08-01 维持产胰岛素细胞功能的方法 Pending CN101232899A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70429505P 2005-08-01 2005-08-01
US60/704,295 2005-08-01

Publications (1)

Publication Number Publication Date
CN101232899A true CN101232899A (zh) 2008-07-30

Family

ID=37561086

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2006800283625A Pending CN101232899A (zh) 2005-08-01 2006-08-01 维持产胰岛素细胞功能的方法

Country Status (10)

Country Link
EP (1) EP1915171B1 (enExample)
JP (2) JP2009503093A (enExample)
CN (1) CN101232899A (enExample)
AU (1) AU2006275424B2 (enExample)
BR (1) BRPI0614489A2 (enExample)
CA (1) CA2617226A1 (enExample)
DK (1) DK1915171T3 (enExample)
ES (1) ES2439455T3 (enExample)
MX (1) MX2008001643A (enExample)
WO (1) WO2007016600A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110187123A (zh) * 2019-05-06 2019-08-30 天津医科大学总医院 一种糖尿病早期诊断生物标志物及其应用

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
JP4681231B2 (ja) 2002-03-20 2011-05-11 マンカインド コーポレイション 吸入装置
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
HUE025151T2 (en) 2004-08-23 2016-01-28 Mannkind Corp Diceto-piperazine salts for drug delivery
MX373000B (es) 2005-09-14 2020-05-21 Mannkind Corp Metodo para formulacion de farmaco basado en el aumento de la afinidad de agentes activos hacia las superficies de microparticulas cristalinas.
CN104383546B (zh) 2006-02-22 2021-03-02 曼金德公司 用于改善包含二酮哌嗪和活性剂的微粒的药物性质的方法
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
MY155524A (en) 2008-06-13 2015-10-30 Mannkind Corp A dry powder inhaler and system for drug delivery
EP2609954B1 (en) 2008-06-20 2021-12-29 MannKind Corporation An interactive apparatus for real-time profiling of inhalation efforts
TWI494123B (zh) 2008-08-11 2015-08-01 Mannkind Corp 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
SI2379100T1 (sl) * 2009-01-08 2015-02-27 Mannkind Corporation Zdravljenje hiperglikemije z GLP-1
MX2011009251A (es) * 2009-03-04 2011-11-18 Mannkind Corp Sistema mejorado de suministro de farmaco en polvo seco.
US8538707B2 (en) 2009-03-11 2013-09-17 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
AU2010259943C1 (en) 2009-06-12 2016-03-03 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
JP5784622B2 (ja) 2009-11-03 2015-09-24 マンカインド コーポレ−ション 吸入活動をシミュレートするための装置及び方法
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
MX353285B (es) 2011-04-01 2018-01-05 Mannkind Corp Paquete de blister para cartuchos farmaceuticos.
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
HK1201475A1 (en) 2011-10-24 2015-09-04 Mannkind Corporation Methods and compositions for treating pain
AU2013289957B2 (en) 2012-07-12 2017-02-23 Mannkind Corporation Dry powder drug delivery systems and methods
US9897565B1 (en) 2012-09-11 2018-02-20 Aseko, Inc. System and method for optimizing insulin dosages for diabetic subjects
US9171343B1 (en) 2012-09-11 2015-10-27 Aseko, Inc. Means and method for improved glycemic control for diabetic patients
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
BR112015023168B1 (pt) 2013-03-15 2021-08-10 Mannkind Corporation Composição de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina cristalina, método de produção de partículas de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina e uso de uma composição de dicetopiperazina cristalina
BR122019026637B1 (pt) 2013-07-18 2023-09-26 Mannkind Corporation Formulações farmacêuticas de pó seco e método para a fabricação de uma formulação de pó seco
CA2920488C (en) 2013-08-05 2022-04-26 Mannkind Corporation Insufflation apparatus and methods
US9486580B2 (en) 2014-01-31 2016-11-08 Aseko, Inc. Insulin management
US9898585B2 (en) 2014-01-31 2018-02-20 Aseko, Inc. Method and system for insulin management
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
US11081226B2 (en) 2014-10-27 2021-08-03 Aseko, Inc. Method and controller for administering recommended insulin dosages to a patient
JP6989262B2 (ja) 2014-10-27 2022-01-05 アセコー インコーポレイテッド 皮下外来患者管理
JP7109155B2 (ja) 2015-06-04 2022-07-29 キッコーマン株式会社 フラビン結合型グルコースデヒドロゲナーゼを用いたグルコースの測定方法
EP3337402B1 (en) 2015-08-20 2026-01-07 Glytec, LLC Diabetes management therapy advisor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0975328A1 (en) * 1997-04-02 2000-02-02 Purdue Research Foundation Method for oral delivery of proteins
ES2395096T3 (es) * 1999-06-29 2013-02-08 Mannkind Corporation Purificación y estabilización de agentes farmacéuticos a base de péptidos y proteínas
GB0217382D0 (en) * 2002-07-26 2002-09-04 Pfizer Ltd Process for making orally consumable dosage forms
EP1605895A4 (en) * 2003-03-06 2011-08-24 Emisphere Tech Inc ORAL INSULIN THERAPIES AND PROTOCOL
US20050153874A1 (en) * 2004-01-12 2005-07-14 Mannkind Corporation Method of reducing serum proinsulin levels in type 2 diabetics

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110187123A (zh) * 2019-05-06 2019-08-30 天津医科大学总医院 一种糖尿病早期诊断生物标志物及其应用
CN110187123B (zh) * 2019-05-06 2022-07-22 天津医科大学总医院 一种糖尿病早期诊断生物标志物及其应用

Also Published As

Publication number Publication date
EP1915171B1 (en) 2013-11-20
AU2006275424A1 (en) 2007-02-08
MX2008001643A (es) 2008-04-07
JP2009503093A (ja) 2009-01-29
JP2015091854A (ja) 2015-05-14
WO2007016600A2 (en) 2007-02-08
ES2439455T3 (es) 2014-01-23
BRPI0614489A2 (pt) 2011-03-29
WO2007016600A3 (en) 2007-05-31
AU2006275424B2 (en) 2013-01-10
CA2617226A1 (en) 2007-02-08
DK1915171T3 (da) 2013-12-09
EP1915171A2 (en) 2008-04-30

Similar Documents

Publication Publication Date Title
EP1915171B1 (en) Method of preserving the function of insulin-producing cells
US20070027063A1 (en) Method of preserving the function of insulin-producing cells
US20200138912A1 (en) Superior control of blood glucose in diabetes treatment
AU2009200894A1 (en) A method of reducing serum proinsulin levels in type 2 diabetics
HK1122213A (en) Method of preserving the function of insulin-producing cells
AU2012203626B2 (en) Superior control of blood glucose in diabetes treatment
HK1152257A (en) Control of blood glucose in diabetes treatment using pulmonarily administered insulin in combination with basal insulin
HK1161557A (en) Control of blood glucose in diabetes treatment using pulmonarily administered insulin in combination with basal insulin
HK1128876B (en) Control of blood glucose in diabetes treatment using pulmonarily administered insulin in combination with basal insulin
HK1118204A (en) Control of blood glucose in diabetes treatment using pulmonarily administered insulin in combination with basal insulin

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1122213

Country of ref document: HK

C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Open date: 20080730

REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1122213

Country of ref document: HK