CN101230351B - Psod表达单元 - Google Patents

Psod表达单元 Download PDF

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Publication number
CN101230351B
CN101230351B CN2007103011915A CN200710301191A CN101230351B CN 101230351 B CN101230351 B CN 101230351B CN 2007103011915 A CN2007103011915 A CN 2007103011915A CN 200710301191 A CN200710301191 A CN 200710301191A CN 101230351 B CN101230351 B CN 101230351B
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CN
China
Prior art keywords
activity
nucleic acid
encoding
acid encoding
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2007103011915A
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English (en)
Chinese (zh)
Other versions
CN101230351A (zh
Inventor
B·克勒格尔
O·策尔德尔
C·克洛普罗格
H·施罗德
S·哈夫纳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Daesang Corp
Original Assignee
BASF SE
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Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Publication of CN101230351A publication Critical patent/CN101230351A/zh
Application granted granted Critical
Publication of CN101230351B publication Critical patent/CN101230351B/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity

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  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN2007103011915A 2003-12-18 2004-12-16 Psod表达单元 Expired - Fee Related CN101230351B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10359660.7 2003-12-18
DE10359660A DE10359660A1 (de) 2003-12-18 2003-12-18 Psod-Expressionseinheiten

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CNA2004800378819A Division CN1894411A (zh) 2003-12-18 2004-12-16 Psod表达单元

Publications (2)

Publication Number Publication Date
CN101230351A CN101230351A (zh) 2008-07-30
CN101230351B true CN101230351B (zh) 2013-02-20

Family

ID=34683563

Family Applications (2)

Application Number Title Priority Date Filing Date
CN2007103011915A Expired - Fee Related CN101230351B (zh) 2003-12-18 2004-12-16 Psod表达单元
CNA2004800378819A Pending CN1894411A (zh) 2003-12-18 2004-12-16 Psod表达单元

Family Applications After (1)

Application Number Title Priority Date Filing Date
CNA2004800378819A Pending CN1894411A (zh) 2003-12-18 2004-12-16 Psod表达单元

Country Status (15)

Country Link
US (3) US20080274516A1 (enExample)
EP (2) EP1697526B1 (enExample)
JP (2) JP2007514426A (enExample)
KR (1) KR20070004580A (enExample)
CN (2) CN101230351B (enExample)
AR (1) AR047152A1 (enExample)
AT (1) ATE486131T1 (enExample)
BR (1) BRPI0417728A (enExample)
CA (1) CA2549171A1 (enExample)
DE (2) DE10359660A1 (enExample)
IN (2) IN2006CH02599A (enExample)
RU (1) RU2006125502A (enExample)
TW (1) TW200602489A (enExample)
WO (1) WO2005059144A1 (enExample)
ZA (1) ZA200605857B (enExample)

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DE102004035065A1 (de) 2004-07-20 2006-02-16 Basf Ag P-ET-TS-Expressionseinheiten
DE102004061846A1 (de) 2004-12-22 2006-07-13 Basf Ag Mehrfachpromotoren
DE102005056668A1 (de) 2005-11-28 2007-05-31 Basf Ag Fermentative Herstellung organischer Verbindungen
EP2386650B1 (en) * 2006-04-07 2013-07-03 Evonik Degussa GmbH Method for producing L-amino acids using the gap promoter
EP1881076A1 (en) * 2006-07-17 2008-01-23 Evonik Degussa GmbH Method for producing L-amino acids
US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
DE102009030342A1 (de) 2009-06-25 2010-12-30 Evonik Degussa Gmbh Verfahren zur fermentativen Herstellung von organisch chemischen Verbindungen
JP5960604B2 (ja) 2009-12-17 2016-08-02 ビーエーエスエフ ソシエタス・ヨーロピアBasf Se カダベリンの生産のための方法及び組換え微生物
DE102010003419B4 (de) 2010-03-30 2019-09-12 Evonik Degussa Gmbh Verfahren zur fermentativen Herstellung von L-Ornithin
US9968030B2 (en) 2010-06-22 2018-05-15 Cnh Industrial Canada, Ltd. Down pressure adjustment device and method for use with a disc opener assembly of an agricultural implement
CN103492553B (zh) 2011-02-22 2018-06-12 巴斯夫欧洲公司 用于生产尸胺的方法和重组微生物
DE102011006716A1 (de) 2011-04-04 2012-10-04 Evonik Degussa Gmbh Mikroorganismus und Verfahren zur fermentativen Herstellung einer organisch-chemischen Verbindung
DE102011118019A1 (de) 2011-06-28 2013-01-03 Evonik Degussa Gmbh Varianten des Promotors des für die Glyzerinaldehyd-3-phosphat-Dehydrogenase kodierenden gap-Gens
KR101335853B1 (ko) * 2011-12-01 2013-12-02 씨제이제일제당 (주) L-아미노산 및 리보플라빈을 동시에 생산하는 미생물 및 이를 이용한 l-아미노산 및 리보플라빈을 생산하는 방법
EP2762571A1 (de) 2013-01-30 2014-08-06 Evonik Industries AG Mikroorganismus und Verfahren zur fermentativen Herstellung von Aminosäuren
WO2016068656A2 (ko) * 2014-10-30 2016-05-06 주식회사 삼양사 사이코스 에퍼머화 효소의 발현 시스템 및 이를 이용한 사이코스의 생산
CN107002112B (zh) 2014-12-10 2021-11-02 巴斯夫欧洲公司 从生物技术产物中除去dna的方法
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
EP3415622A1 (en) 2017-06-14 2018-12-19 Evonik Degussa GmbH Method for production of fine chemicals using a corynebacterium secreting modified alpha-1,6-glucosidases
CN109536465B (zh) * 2017-09-21 2020-11-13 中国医学科学院医药生物技术研究所 筛选抗结核药物的组合物、筛选模型和筛选方法
CN109182235B (zh) * 2018-08-29 2021-03-30 江南大学 一种n端序列元件在调控枯草芽孢杆菌表达蛋白中的应用
CN111549027A (zh) * 2020-04-28 2020-08-18 天津大学 一种谷氨酸棒杆菌高强度启动子Psod-sx及应用

Citations (2)

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WO2002040679A2 (en) * 2000-11-15 2002-05-23 Archer-Daniels-Midland Company Corynebacterium glutamicum promoters
CN1451047A (zh) * 1999-06-25 2003-10-22 Basf公司 编码胁迫、抗性和耐受性蛋白的谷氨酸棒杆菌基因

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US6696561B1 (en) * 1909-07-09 2004-02-24 Basf Aktiengesellschaft Corynebacterium glutamicum genes encoding proteins involved in membrane synthesis and membrane transport
JPS5835197A (ja) * 1981-08-26 1983-03-01 Kyowa Hakko Kogyo Co Ltd プラスミドpcg2
US4601893A (en) 1984-02-08 1986-07-22 Pfizer Inc. Laminate device for controlled and prolonged release of substances to an ambient environment and method of use
GB2165546B (en) 1984-08-21 1989-05-17 Asahi Chemical Ind A plasmid containing a gene for tetracycline resistance and dna fragments derived therefrom
DE4027453A1 (de) 1990-08-30 1992-03-05 Degussa Neue plasmide aus corynebacterium glutamicum und davon abgeleitete plasmidvektoren
EP0693558B1 (en) 1994-07-19 2002-12-04 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Trehalose and its production and use
DE4440118C1 (de) * 1994-11-11 1995-11-09 Forschungszentrum Juelich Gmbh Die Genexpression in coryneformen Bakterien regulierende DNA
JPH10229891A (ja) 1997-02-20 1998-09-02 Mitsubishi Rayon Co Ltd マロン酸誘導体の製造法
KR20070087095A (ko) * 1999-06-25 2007-08-27 바스프 악티엔게젤샤프트 스트레스 저항성 및 내성 단백질을 코딩하는코리네박테리움 글루타미쿰 유전자
US7270984B1 (en) * 1999-06-25 2007-09-18 Basf Aktiengesellschaft Polynucleotides encoding a 6-phosphogluconolactonase polypeptide from corynebacterium glutamicum
KR20070087090A (ko) * 1999-06-25 2007-08-27 바스프 악티엔게젤샤프트 탄소 대사 및 에너지 생산과 관련된 단백질을 코딩하는코리네박테리움 글루타미쿰 유전자
US6822084B1 (en) * 1999-06-25 2004-11-23 Basf Aktiengesellschaft Corynebacterium glutamicum genes encoding stress, resistance and tolerance proteins
JP4623825B2 (ja) * 1999-12-16 2011-02-02 協和発酵バイオ株式会社 新規ポリヌクレオチド
DE10046870A1 (de) 2000-09-20 2002-03-28 Basf Ag Verfahren zur Veränderung des Genoms von Corynebakterien
EP1375664B1 (en) * 2001-03-30 2009-11-04 Ajinomoto Co., Inc. Method for the secretion and production of protein

Patent Citations (2)

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CN1451047A (zh) * 1999-06-25 2003-10-22 Basf公司 编码胁迫、抗性和耐受性蛋白的谷氨酸棒杆菌基因
WO2002040679A2 (en) * 2000-11-15 2002-05-23 Archer-Daniels-Midland Company Corynebacterium glutamicum promoters

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MERKAMM MURIEL ET AL.CloningofthesodAgenefromCorynebacteriummelassecolaandroleofsuperoxidedismutasein cellularviability.JOURNAL OF BACTERIOLOGY183 4.2001,183(4),第1287页右栏、附图3.
MERKAMM MURIEL ET AL.CloningofthesodAgenefromCorynebacteriummelassecolaandroleofsuperoxidedismutasein cellularviability.JOURNAL OF BACTERIOLOGY183 4.2001,183(4),第1287页右栏、附图3. *

Also Published As

Publication number Publication date
BRPI0417728A (pt) 2007-04-03
US8071365B2 (en) 2011-12-06
DE502004011835D1 (de) 2010-12-09
IN2008CH00416A (enExample) 2008-09-19
JP4800341B2 (ja) 2011-10-26
IN2006CH02599A (enExample) 2007-06-08
ZA200605857B (en) 2008-01-08
TW200602489A (en) 2006-01-16
AR047152A1 (es) 2006-01-11
US20080274516A1 (en) 2008-11-06
WO2005059144A1 (de) 2005-06-30
EP1697526B1 (de) 2010-10-27
CA2549171A1 (en) 2005-06-30
CN101230351A (zh) 2008-07-30
JP2007514426A (ja) 2007-06-07
JP2008212154A (ja) 2008-09-18
ATE486131T1 (de) 2010-11-15
DE10359660A1 (de) 2005-07-28
US20090004705A1 (en) 2009-01-01
KR20070004580A (ko) 2007-01-09
EP1697526A1 (de) 2006-09-06
US20100062535A1 (en) 2010-03-11
CN1894411A (zh) 2007-01-10
EP1918378A1 (de) 2008-05-07
RU2006125502A (ru) 2008-01-27

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
TR01 Transfer of patent right

Effective date of registration: 20170615

Address after: Seoul, South Kerean

Patentee after: DAESANG Corp.

Address before: Ludwigshafen, Germany

Patentee before: BASF SE

Effective date of registration: 20170615

Address after: Ludwigshafen, Germany

Patentee after: BASF SE

Address before: Ludwigshafen, Germany

Patentee before: Basf AG

TR01 Transfer of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20130220

CF01 Termination of patent right due to non-payment of annual fee