CN101229250A - Use of prinsepia utilis royle oil on preventing bedsore - Google Patents

Abstract

The invention relates to an application of prinsepia utilis royle oil in bedsore prevention. The invention can be made into emulsion, cream paste or oil, which is effective for skin care and bedsore prevention.

Description

The application of Princepia utilis oil in preventing pressure ulcers

Technical field

The present invention relates to the application of Princepia utilis oil in preventing pressure ulcers.Can be prepared into Emulsion, cream ointment or oil preparation, effectively nursing skin has the prevention decubital ulcer to take place.

Background technology

Decubital ulcer is one of clinical most common complication, according to the statistics of domestic and foreign literature to the decubital ulcer incidence rate, 148 tame acute care mechanism decubital ulcer incidence rates are 9.2%, in section hospital and the welfare hospital decubital ulcer incidence rate be 23.0%-27.5% (Zhang Changhui. adopt point system to prevent decubital ulcer at risk factor. foreign medical science nursing fascicle, 1996,15 (5): 201).And it is big more to be the age, and ratio is high more.As seen decubital ulcer is an a great problem in the clinical care.

According to Perheger etc. to 2373 observations that the patient did; just have 1 example to suffer from decubital ulcer in the about 10 routine inpatients, prevalence and age are proportionate, more than 40 years old the patient than the prevalence of patient below 40 years old exceed 6-7 doubly (Wu Haihua. the bedsore prevention and treatment new development. nurse in Shanghai; 2003,5 (3): 51).Along with increasing age, cognitive function has going down in various degree, think now Cognitive function damage also be an important risk factor taking place of decubital ulcer (Li Wei. pressure ulcer nursing new development. the nurse studies magazine, 2002,17 (1): 201), this shows that the old people is the high-risk group that decubital ulcer takes place.

After decubital ulcer takes place, all can cause bigger injury, increase the difficulty of nursery work simultaneously patient's body and mind.Because it is how restricted that patient's action of decubital ulcer takes place, the difficulty of healing is also than higher.

Therefore should be putting prevention first to the control of decubital ulcer, except mostly being patient stands up, also to pay attention to the nursing of skin, guarantee the unobstructed of local blood.

Under study for action, we find that Princepia utilis oil is used for the decubital ulcer patient, can effectively prevent the generation of patient's decubital ulcer.Also can make patient's skin obtain good maintenance simultaneously, not have zest (Princepia utilis itself is to can be used as edible oil) again, be very good nursing care of decubitus ulcer product.

Princepia utilis oil is that the seed of rosaceous plant Folium Prinsepiae Utilis Prinsepia Utilis Royle obtains by squeezing or method of extraction.The fruit of Folium Prinsepiae Utilis is practised and is claimed Princepia utilis, so the seed oil habit is called Princepia utilis oil.Folium Prinsepiae Utilis mainly is grown in the plateau and the mountain region of China's cloud, expensive, river, Taiwan height above sea level 1800-3200 rice.

Minorities in Yunnan has the custom of using Princepia utilis oil, and tradition is thought, drinks a spot of Princepia utilis oil in red-letter day, can guarantee 1 year healthy.Princepia utilis oil has good skin care effect, is again the pollution-free regional growing plants in plateau, originally uses as edible oil again.

In recent years, the result of study to Princepia utilis oil shows:

Princepia utilis oil have certain blood lipid regulation, antioxidation and vitro inhibition platelet aggregation effect (Zhang Xiaopeng, Lin Xiaoming. Princepia utilis oil blood lipid regulation and to the influence of human blood platelets aggregation in vitro effect. health research .2005,34 (1): 79).To the damage gastric mucosa have protective effect (Liu calls on, Chen Shujie, Mo Zhengji, etc. the blue or green Na oil of compound recipe causes the protection of mice gastric mucosa injury to indometacin/ethanol. West China pharmaceutical journal, 2003,18 (3): 232-233).

Summary of the invention

Princepia utilis oil is applied to prevent pressure ulcers, and multiple mode can be arranged:

1. directly use: Princepia utilis oil evenly is applied to the position of the frequent pressurized of patient, and carries out the massage of appropriateness, promptly use 100% Princepia utilis oil.

2. with its matrix oil fit applications such as (as Semen pruni armeniacae oil, olive oil, Semen Tritici aestivi germ oil, mineral oil), the shared weight of 15%≤Princepia utilis oil＜100%.

3. Princepia utilis oil can be made into Emulsion, and shared weight ratio is 5-15% in Emulsion.

4. Princepia utilis oil can be made into the cream cream, and shared weight ratio is 15-30% in the cream cream.

5. the product made of Princepia utilis oil is used and is prevented pressure ulcers, and main embodiment can effectively prevent the generation of decubital ulcer, keeps skin complete.

The specific embodiment

Embodiment 1:

With the bottling of 100% Princepia utilis oil, sterilization, packing.

Embodiment 2:

Prescription: Princepia utilis oil 96%

VD 1％

VA 1％

VC 1

VE 0.8％

Ethyl hydroxybenzoate 0.2%

Method for making: each component is mixed in will filling a prescription, and brute force stirred 15 minutes, made its mix homogeneously, and the degassing is pressed mill by colloid mill, forms uniform and stable liquid, and mixed liquor is bottled after filtering, sterilization, packing.

Embodiment 3:

Prescription: Princepia utilis oil 80%

Olive oil 19.8%

Ethyl hydroxybenzoate 0.2%

Method for making: each component is mixed in will filling a prescription, and brute force stirred 10 minutes, made its mix homogeneously, and the degassing is pressed mill by colloid mill, forms uniform and stable liquid, and mixed liquor is bottled after filtering, packing.

Embodiment 4:

Prescription: Princepia utilis oil 15%

Semen Tritici aestivi germ oil 45%

Semen pruni armeniacae oil 39.8%

Ethyl hydroxybenzoate 0.2%

Method for making: each component is mixed in will filling a prescription, and brute force stirred 20 minutes, made its mix homogeneously, and the degassing is pressed mill by colloid mill, forms uniform and stable liquid, and mixed liquor is bottled after filtering, sterilization, packing.

Embodiment 5:

Prescription: Princepia utilis oil 15%

Cera Flava 3.0%

Lanoline 2.0%

Stearic acid 3.0%

Isopropyl myristate 1.0%

Propylene glycol 5.0%

Triethanolamine 1.5%

Purified Water adds to 100%

Method for making: with water dissolution propylene glycol, triethanolamine, etc. water-soluble component, be heated to 85 ℃ after, under agitation join in 85 ℃ the oil phase, be stirred to 40 ℃, bottling, sterilization, packing.

Embodiment 6:

Prescription: Princepia utilis oil 5%

Liquid lanolin 3.0%

Stearic acid 2.5%

Monoglyceride 2.0%

Triethanolamine 1.0%

Purified Water adds to 100%

Method for making: water and oil phase heat respectively under agitation inject water oil phase emulsifying to 80 ℃, stir when being cooled to 40 ℃, add essence, fully mixing.

Embodiment 7:

Prescription: Princepia utilis oil 30%

Mineral oil 5%

Lanoline 12%

Hexadecanol 8%

American Avocado Tree oil 5%

Glyceryl monostearate 8%

VC 1％

Vitamin E 0.8%

Purified Water adds to 100%

Methyl hydroxybenzoate 0.2%

Preparation technology: oil phase, be heated to 80 ℃, make its fusing evenly, by filter, slowly add entry again, powerful stir about 15 minutes is kept 80 ℃, emulsifying (3000r/min) 7 minutes, the degassing, slowly cool to 40 ℃, add nipalgin, continue to stir, be cooled to 25 ℃, bottling.

With the sample of the above embodiment gained that carries out, carry out clinical trial and observe, specifically test as follows:

Experimental example:

Sample is used in experiment: get representative sample, be respectively experimental example 1,2,6,7 prepared samples.

Case is selected: for getting rid of other disease factor, select sickbed patients 164 examples due to wound (fracture) and the osteonecrosis of femoral head, the course of disease is the person more than 30 days.Man's 113 examples, women 51 examples, age 55-79 year.

Experiment grouping: selected case is divided into 1 group of treatment (adopting the sample of experimental example 1 preparation, 36 examples, wherein women's 10 examples) at random, treat 2 groups and (adopt the sample of experimental example 2 preparations, 25 examples, wherein women's 10 examples), treat 3 groups and (adopt the sample of experimental example 6 preparations, 27 examples, women's 10 examples wherein), treat 4 groups and (adopt the sample of experimental example 7 preparations, 25 examples, women's 10 examples wherein) and matched group (45 examples, wherein women's 11 examples).

Therapeutic Method: matched group timing turning over every day 5 times.The treatment group adopts the Princepia utilis product to the pressurized position, is applied to part in compression, and massages 5 minutes, every day 3 times), the same with matched group, every day, timing turning over was 5 times.Carry out one month paired observation.

Evaluation methodology: so that decubital ulcer not to take place serves as effective; Being considered as of generation decubital ulcer is invalid.The case that decubital ulcer does not take place is effective percentage divided by this group number.The case sum that decubital ulcer does not take place all treatment groups sees Table 1 divided by treatment group total number of persons for the total effective rate experimental result.

Table 1 Princepia utilis oil product prevention decubital ulcer effect observed result

Experimental result shows, compares with matched group, and the prepared product of Princepia utilis oil has fabulous prevention decubital ulcer effect.

Claims (8)

1. Princepia utilis oil in preventing pressure ulcers purposes.
2. 2. Princepia utilis oil according to claim 1 in preventing pressure ulcers purposes, it is characterized in that Princepia utilis oil is that the seed of rosaceous plant Folium Prinsepiae Utilis Prinsepia Utilis Royle obtains by squeezing or method of extraction.
3. 3. Princepia utilis oil according to claim 1 in preventing pressure ulcers purposes, it is characterized in that Princepia utilis oil shared weight ratio in product is 5-100%.
4. 4. Princepia utilis oil according to claim 1 in preventing pressure ulcers purposes, it is characterized in that Princepia utilis oil shared weight ratio in product is 5-15%.
5. 5. Princepia utilis oil according to claim 1 in preventing pressure ulcers purposes, it is characterized in that Princepia utilis oil shared weight ratio in product is 15-30%.
6. 6. Princepia utilis oil according to claim 1 in preventing pressure ulcers purposes, it is characterized in that Princepia utilis oil shared weight ratio in product is 30-80%.
7. 7. Princepia utilis oil according to claim 1 in preventing pressure ulcers purposes, it is characterized in that product is Emulsion, cream cream and oil preparation.
8. 8. Princepia utilis oil according to claim 1 in preventing pressure ulcers purposes, it is characterized in that product can effectively prevent the generation of decubital ulcer.