CN101229249A - Use of prinsepia utilis royle oil on preparing products for treating mosquito sting - Google Patents
Use of prinsepia utilis royle oil on preparing products for treating mosquito sting Download PDFInfo
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- CN101229249A CN101229249A CNA2007100025475A CN200710002547A CN101229249A CN 101229249 A CN101229249 A CN 101229249A CN A2007100025475 A CNA2007100025475 A CN A2007100025475A CN 200710002547 A CN200710002547 A CN 200710002547A CN 101229249 A CN101229249 A CN 101229249A
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Abstract
The invention relates to an application of prinsepia utilis royle oil in the products preparation for treating mosquito bites; the product which is prepared with prinsepia utilis royle has good antipruritic and detumescent effect; the product can be made into emulsions or oils to achieve the antipruritic effect and detumescence effect.
Description
Technical field
The present invention relates to the application that Princepia utilis oil is used to prepare treatment mosquito bite product.Can be prepared into Emulsion or oil preparation is used for subsiding a swelling only overworked.
Background technology
In summer, mosquito wreaks havoc, and human body very easily is bit by insect, and the overworked symptom of scabies appears in the back regular meeting of biting, and presents red and swollen state.Promptly influence routine work and rest, the people is constantly scratched, cause dermatitis then or stay cicatrix, or allergic dermatitis reaction occurs, prolongedly do not heal.The dermatitis that mosquito bite causes is very common.Mosquito is stabbed skin by its mouthpart, and its saliva or venom are invaded skin, owing to contain multiple antigenic component in the leachate of saliva of mosquito or poison gland, these antigens can produce atopic reaction with antibody and cause inflammation after entering human body skin.The local severe reactions such as bulla, hemorrhagic necrosis that produce of indivedual infants are dermatology common disease diseases in summer when serious.
As the position of position outside being exposed to summers such as face, upper limb, lower limb of biting, also can individual image be impacted, and then influence work and life.Therefore, the product of effectively treating mosquito bite will bring great convenience to people.
Discover that through us Princepia utilis oil is splendid to treatment mosquito bite effect, can receive better effect as share then with other Related product.
Princepia utilis oil is that the seed of rosaceous plant Folium Prinsepiae Utilis Prinsepia Utilis Royle obtains by squeezing or method of extraction.The fruit of Folium Prinsepiae Utilis is practised and is claimed Princepia utilis, so seed oil practises and be called blue or green perverse fruit oil.Folium Prinsepiae Utilis mainly is grown in the plateau and the mountain region of China's cloud, expensive, river, Taiwan height above sea level 1800-3200 rice.
Minorities in Yunnan has the custom of using Princepia utilis oil, and tradition is thought, drinks a spot of Princepia utilis oil in red-letter day, can guarantee 1 year healthy.
In recent years, Princepia utilis oil has been carried out a series of research.Result of study shows:
Princepia utilis oil have certain blood lipid regulation, antioxidation and vitro inhibition platelet aggregation effect (Zhang Xiaopeng, Lin Xiaoming. Princepia utilis oil blood lipid regulation and to the influence of human blood platelets aggregation in vitro effect. health research .2005,34 (1): 79).To the damage gastric mucosa have protective effect (Liu calls on, Chen Shujie, Mo Zhengji, etc. the blue or green Na oil of compound recipe causes the protection of mice gastric mucosa injury to indometacin/ethanol. West China pharmaceutical journal, 2003,18 (3): 232 233).
Summary of the invention
Princepia utilis oil is applied to mosquito bite can multiple mode:
1. directly use: Princepia utilis oil evenly is applied to the mosquito bite affected part, promptly is the Princepia utilis oil with 100%.
2. with Oleum menthae, tea tree oil, eucalyptus oil and other matrix oil fit applications such as (as Semen pruni armeniacae oil, olive oil, Semen Tritici aestivi germ oil, mineral oil), the shared weight of 15%≤Princepia utilis oil<100%.
3. Princepia utilis oil can be made into Emulsion, and shared weight ratio is 5-15% in Emulsion.
4. the product made of Princepia utilis oil mainly shows as antipruritic, detumescence on the treatment mosquito bite.
The specific embodiment
Embodiment 1:
With the bottling of 100% Princepia utilis oil, sterilization, packing.
Embodiment 2:
Prescription: Princepia utilis oil 96%
Oleum menthae 1%
Tea tree oil 1%
Eucalyptus oil 1%
Vitamin E 0.8%
Ethyl hydroxybenzoate 0.2%
Method for making: each component is mixed in will filling a prescription, and brute force stirred 15 minutes, made its mix homogeneously, and the degassing is pressed mill by colloid mill, forms uniform and stable liquid, and mixed liquor is bottled after filtering, sterilization, packing.
Embodiment 3:
Prescription: Princepia utilis oil 80%
Tea tree oil 1%
Olive oil 18.8%
Ethyl hydroxybenzoate 0.2%
Method for making: each component is mixed in will filling a prescription, and brute force stirred 10 minutes, made its mix homogeneously, and the degassing is pressed mill by colloid mill, forms uniform and stable liquid, and mixed liquor is bottled after filtering, packing.
Embodiment 4:
Prescription: Princepia utilis oil 15%
Eucalyptus oil 1%
Semen pruni armeniacae oil 83.8%
Ethyl hydroxybenzoate 0.2%
Method for making: each component is mixed in will filling a prescription, and brute force stirred 20 minutes, made its mix homogeneously, and the degassing is pressed mill by colloid mill, forms uniform and stable liquid, and mixed liquor is bottled after filtering, sterilization, packing.
Embodiment 5:
Prescription: Princepia utilis oil 15%
Cera Flava 3.0%
Lanoline 2.0%
Stearic acid 3.0%
Isopropyl myristate 1.0%
Propylene glycol 5.0%
Triethanolamine 1.5%
Purified Water adds to 100%
Method for making: with water dissolution propylene glycol, triethanolamine, etc. water-soluble component, be heated to 85 ℃ after, under agitation join in 85 ℃ the oil phase, be stirred to 40 ℃, bottling, sterilization, packing.
Embodiment 6:
Prescription: Princepia utilis oil 5%
Liquid lanolin 3.0%
Stearic acid 2.5%
Monoglyceride 2.0%
Triethanolamine 1.0%
Purified Water adds to 100%
Method for making: water and oil phase heat respectively under agitation inject water oil phase emulsifying to 70 ℃, stir when being cooled to 40 ℃, add essence, fully mixing.
With the sample of the above embodiment gained that carries out, carry out clinical trial and observe, specifically test as follows:
Experimental example:
Sample is used in experiment: get representative sample, be respectively experimental example 1,2,6 prepared samples.
Experiment is divided into groups: select the pruritus symptom to be occurred at the place of biting by mosquito bite, and red and swollen healthy people 186 people occur, be divided into three groups: be respectively treatment group 1 (70 people, the sample that uses experimental example 1 method to prepare); Treatment group 2 (60 people, the sample that uses experimental example 2 methods to prepare); Treatment group 3 (56 people, the sample that uses experimental example 6 methods to prepare).
Therapeutic Method: sample thief evenly is applied to the affected part.
Evaluation methodology: end overworked effect standard: antipruritic at once after smearing, for effective; 1 minute only overworked, and effect is better; Be coated with 3-5 time in 3 minutes, reach and end overworked effect, for effect general; Repeatedly smear not antipruritic, for invalid.
The detumescence effect standard: smeared back 24 hours, the red and swollen disappearance is for effective; 24 hours, redness was obviously dwindled (reduced 1/2), and effect is better; Affected part pneumonedema, but the area that reddens do not see obviously and dwindle, for effect general; Redness remains unchanged or increases the weight of, for invalid.
Effective and effect number addition preferably divided by this group number, are obvious effective rate; Effective, effect better and the general number addition of effect divided by this group number, is effective percentage.Experimental result sees Table 1, table 2.
Antipruritic observed result behind table 1 mosquito bite
Effective | Effect is better | Effect is general | Invalid | Obvious effective rate % | Effective percentage % | |
Treatment group 1 | 13 | 52 | 4 | 1 | 92.8 | 98.6 |
Treatment group 2 | 15 | 43 | 2 | 0 | 96.7 | 100 |
Treatment group 3 | 9 | 37 | 8 | 2 | 82.1 | 96.4 |
The observed result of subsiding a swelling behind table 2 mosquito bite
Effective | Effect is better | Effect is general | Invalid | Obvious effective rate % | Effective percentage % | |
Treatment group 1 | 3 | 55 | 8 | 4 | 82.8 | 94.3 |
Treatment group 2 | 4 | 39 | 15 | 2 | 71.7 | 96.7 |
Treatment group 3 | 1 | 37 | 9 | 9 | 67.8 | 83.9 |
Experimental result shows, Princepia utilis oil has extraordinary effect aspect the antipruritic and detumescence behind mosquito bite, as shared with Oleum menthae, eucalyptus oil, the Camellia sinensis wet goods of the similar effect of tool, and better effects if.
Claims (6)
1. Princepia utilis oil is used to prepare the purposes of treatment mosquito bite product.
2. be used to prepare the purposes of treatment mosquito bite product by the described Princepia utilis oil of claim 1, it is characterized in that Princepia utilis oil is that the seed of rosaceous plant Folium Prinsepiae Utilis Prinsepia Utilis Royle obtains by squeezing or method of extraction.
3. be used to prepare the purposes of treatment mosquito bite product by the described Princepia utilis oil of claim 1, it is characterized in that Princepia utilis oil shared weight ratio in product is 5-100%.
4. be used to prepare the purposes of treatment mosquito bite product by the described Princepia utilis oil of claim 1, it is characterized in that Princepia utilis oil shared weight ratio in product is 15-80%.
5. be used to prepare the purposes of treatment mosquito bite product by the described Princepia utilis oil of claim 1, it is characterized in that product is Emulsion and oil preparation.
6. be used to prepare the purposes of treatment mosquito bite product by the described Princepia utilis oil of claim 1, it is characterized in that product has antipruritic, detumescence effect.
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CNA2007100025475A CN101229249A (en) | 2007-01-26 | 2007-01-26 | Use of prinsepia utilis royle oil on preparing products for treating mosquito sting |
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CNA2007100025475A CN101229249A (en) | 2007-01-26 | 2007-01-26 | Use of prinsepia utilis royle oil on preparing products for treating mosquito sting |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102113982A (en) * | 2011-01-28 | 2011-07-06 | 武汉耦合医学科技有限责任公司 | Waterless gel medical nursing product for puerpera breast and preparation method thereof |
CN102133165A (en) * | 2011-03-18 | 2011-07-27 | 厦门百度科技开发有限公司 | Mosquito repelling lemon liquid and preparation method thereof |
CN110051626A (en) * | 2018-01-18 | 2019-07-26 | 杜权 | A kind of two-phase oil formulation and its application |
CN110478420A (en) * | 2019-09-24 | 2019-11-22 | 舒晓燕 | A kind of open air preservative oil and preparation method thereof |
-
2007
- 2007-01-26 CN CNA2007100025475A patent/CN101229249A/en active Pending
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102113982A (en) * | 2011-01-28 | 2011-07-06 | 武汉耦合医学科技有限责任公司 | Waterless gel medical nursing product for puerpera breast and preparation method thereof |
CN102113982B (en) * | 2011-01-28 | 2012-05-09 | 武汉耦合医学科技有限责任公司 | Waterless gel medical nursing product for puerpera breast and preparation method thereof |
CN102133165A (en) * | 2011-03-18 | 2011-07-27 | 厦门百度科技开发有限公司 | Mosquito repelling lemon liquid and preparation method thereof |
CN110051626A (en) * | 2018-01-18 | 2019-07-26 | 杜权 | A kind of two-phase oil formulation and its application |
CN110051626B (en) * | 2018-01-18 | 2022-10-04 | 杜权 | Two-phase oil preparation and application thereof |
CN110478420A (en) * | 2019-09-24 | 2019-11-22 | 舒晓燕 | A kind of open air preservative oil and preparation method thereof |
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Open date: 20080730 |