CN101218910B - Eupatorium herb microemulsion and method for producing the same - Google Patents
Eupatorium herb microemulsion and method for producing the same Download PDFInfo
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- CN101218910B CN101218910B CN2007100728485A CN200710072848A CN101218910B CN 101218910 B CN101218910 B CN 101218910B CN 2007100728485 A CN2007100728485 A CN 2007100728485A CN 200710072848 A CN200710072848 A CN 200710072848A CN 101218910 B CN101218910 B CN 101218910B
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Abstract
The invention relates to an aircraft grass micro-emulsion which contains 0.01 to 35 percent of aircraft grass extract, 1 to 35 percent of solvent, 0.5 to 10 percent of cosolvent, 1 to 35 percent of emulsifier, 0.5 to 10 percent of stabilizing agent, 19.5 to 95.5 percent of water and 0.05 to 10 percent of acidity-basicity modifier and provides a method for preparing the micro-emulsion. The aircraft grass micro-emulsion of the invention uses the water part or a preparation formulation which completely replaces an organic solvent with the help of the emulsifier to distribute the aircraft grass extract uniformly in the water to form a preparation with water as a stroma and add the stabilizing agent in the water so as to prepare a repellent product with high quality. The invention is a novel biological pesticide with the advantages of wide source, high utilization ratio, simple technique and low manufacture cost.
Description
Technical field
The present invention relates to a kind of repellant, especially relating to a kind of is the eupatorium herb microemulsion and preparation method thereof of active ingredient with the fragrant eupatorium herb extract
Background technology
Fragrant eupatorium herb (Eupatorium odoratum) is perennial growing thickly property draft of composite family Eupatorium or undershrub, claims poolroot again, high 1～3m, and rhizome is sturdy.Belong to a kind of invasive weed in China, be distributed widely in Hainan, Guangdong, Guangxi, Yunnan, Guizhou, and provinces and regions such as Hong Kong, Macao and Taiwan.It has characteristics such as Net Photosynthetic Rate is big, photosynthetic capacity strong, growth is fast, and as a kind of invasive weed, China all will spend a large amount of manpower and materials every year and prevent and treat.When the height of fragrant eupatorium herb reaches 15cm or when higher, just can influence other herbal growth significantly, except that winning honour for, strive fertilizer with other plant, striving the water, can also produce allelochemical, suppress the growth of contiguous plant.The leaf of fragrant eupatorium herb is poisonous, contains coumarin, wipes skin with leaf and can cause redness, foaming, eats tender leaf by mistake and can cause dizziness, vomiting, causes that also domestic animal and fish poison, and also can cause the food refusal reaction to insect.To the study on prevention work of this instruction plant, also there is not the better controlled method at present.In recent years, fragrant eupatorium herb is drawing attention aspect the exploitation of botanical pesticide and is carrying out many researchs, finds that this careless extract has good lay eggs repellent action and desinsection, antibacterial, activity of weeding to insect.
A large amount of uses of traditional chemical agricultural chemicals not only cause the pesticide resistance of insect also to cause environmental pollution, increase year by year as the pesticide residues in soil, underground water and the agricultural product, have endangered the safety of the mankind and animal.The exploitation of botanical pesticide in recent years causes the attention of industry further.Based on fragrant eupatorium herb to characteristics such as the repellent action of some insect and desinsection, antibacterial, activity of weeding, how developing a kind of is the novel biopesticide of active component with the fragrant eupatorium herb extract, this instruction plant is changed harmful to treasure, also become industry one of direction of the prevention and control of this plant species research.
Summary of the invention
The invention provides a kind of eupatorium herb microemulsion and preparation method thereof, overcome other botanical pesticide insufficient raw material, can't produce in a large number, and chemical pesticide is to people, animal toxicity height, is difficult to degraded in environment, and insect is easy to generate shortcomings such as pesticide resistance, having abundant raw material is easy to get, easily degraded, noresidue, little to environmental influence; Its mode of action uniqueness can effectively be alleviated pest resistance to insecticide and produce, and to pest efficient, to characteristics such as people, animal safety.Its preparation form and environmental friendliness have demonstrated fully the advantage of microemulsion.
The present invention solves the problems of the technologies described above the technical scheme that is adopted to be:
A kind of eupatorium herb microemulsion comprises following component: fragrant eupatorium herb extract, solvent, cosolvent, emulsifier, stabilizing agent, water and acidity-basicity regulator.
The shared mass percent of above-mentioned each component can be:
Fragrant eupatorium herb extract 0.01%～35%
Solvent 1%～35%
Cosolvent 0.5%～10%
Emulsifier 1%～35%
Stabilizing agent 0.5%～10%
Water 19.5%～95.5%
Acidity-basicity regulator 0.05%～10%
Described fragrant eupatorium herb extract is:
The complete stool crushed material of A, fragrant eupatorium herb, with in methyl alcohol, ethanol, ethylene glycol, propyl alcohol, benzinum, chloroform, ethyl acetate, acetone, the cyclohexane a kind of, two or three, crushed material is soaked extraction 1～10 time, the ratio of crushed material and solvent can be 1:1～1:10, with extract be condensed into paste get final product the fragrant eupatorium herb extract; Or
B, with the paste among the A, with in methyl alcohol, ethanol, ethylene glycol, propyl alcohol, benzinum, chloroform, ethyl acetate, acetone, the cyclohexane a kind of, two or three, paste is extracted 1～10 time, the ratio of paste and solvent can be 1:1～1:10, with extract be condensed into paste get final product the fragrant eupatorium herb extract.
Preferably, described solvent is one or more the mixture that is selected from methyl alcohol, ethanol, ethylene glycol, propyl alcohol, benzinum, chloroform, ethyl acetate, acetone and the cyclohexane.
Preferably, described cosolvent is one or more the mixture that is selected from methyl alcohol, ethanol, acetone, isoamyl alcohol, butyl glycol ether, ethyl acetate, chloroform, the dimethyl sulfoxide (DMSO).
Preferably, described emulsifier is one or more the mixture in the phenethyl phenol polyethenoxy ether that is selected from alkyl benzene sulphonate sodium salt (or calcium, magnesium, aluminium, barium salt etc.), alkylsurfuric acid sodium salt, styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether disulfonic acid magnesium salts, alkylammonium salt, triethanolamine salt, benzylbiphenyl phenol polyethenoxy ether, n=15～30, phenethyl phenol polyethenoxy polyethenoxy ether, polyoxyethylene nonylphenol ether, alkylphenol polyoxyethylene formaldehyde condensation products, the xenol APEO.
Preferably, described stabilizing agent is one or more the mixture that is selected from 3-chloro-1,2 epoxy prapane, butyl glycidyl ether, phenyl glycidyl ether, methyl glycidyl ether, polyethylene glycol diglycidyl ether, the sodium sorbate.
Water can be deionized water, distilled water, running water.
Preferably, described acidity-basicity regulator is sodium hydroxide, ammoniacal liquor, acetic acid or hydrochloric acid.
A kind of as above-mentioned eupatorium herb microemulsion preparation method, it is characterized in that: the extract with fragrant eupatorium herb under agitation dissolves with solvent in proportion earlier, under agitation add cosolvent, emulsifier, stabilizing agent, acidity-basicity regulator then successively, after fully mixing, add entry again, mix, left standstill 1～5 hour, promptly can be made into microemulsion, packing.
The invention provides a kind of novel, efficient, low toxicity, pollution-free, to the person poultry safety with can alleviate the eupatorium herb microemulsion of pest resistance to insecticide.This formulation is the formulation with water section or whole replace organic solvents, it is by the effect of emulsifier, the fragrant eupatorium herb extract is distributed in uniformly to have formed in the water with water be the preparation of matrix, add stabilizing agent therein, thereby make high-quality repellant product, raw material sources of the present invention are extensive, the availability height, technology is simple, and production cost is low, is a kind of novel biopesticide.
The present invention has following advantage or good effect: 1. preparation is a raw material with the instruction plant fragrant eupatorium herb, changes harmful to treasure, and has bigger ecological benefits and social benefit; 2. be matrix with water, the flash-point height does not burn and does not explode, and produces, stores and use all safety; 3. environmental pollution is little, and is comparatively safe to the producer, user and environment; 4. can effectively alleviate the pesticide resistance problem that general insecticide brings; 5. the working condition of preparation is simple, and the producer that normal temperature can be produced missible oil down all can produce said preparation.
Brief Description Of Drawings
Shown in Figure 1 is eupatorium herb microemulsion preparation flow figure of the present invention.
Embodiment
One, embodiment
Embodiment 1:
In the triangular flask of the 1000ml that agitator is housed, add the 10g solvent earlier, add 10g fragrant eupatorium herb extract again, stirring and dissolving is even, under agitation add 5g cosolvent, 10g emulsifier, 5g stabilizing agent and 5g acidity-basicity regulator successively, add the 955g running water after stirring again, continue to mix, leave standstill got final product in about 1 hour 1% eupatorium herb microemulsion.
Embodiment 2:
In the triangular flask of the 1000ml that agitator is housed, add the 80g solvent earlier, add 100g fragrant eupatorium herb extract again, stirring and dissolving is even, under agitation add 20g cosolvent, 130g emulsifier, 50g stabilizing agent and 5g acidity-basicity regulator successively, add the 615g deionized water after stirring again, continue to mix, leave standstill got final product in about 1 hour 10% eupatorium herb microemulsion.
Embodiment 3:
In the triangular flask of the 1000ml that agitator is housed, add the 100g solvent earlier, add 150g fragrant eupatorium herb extract again, stirring and dissolving is even, under agitation add 20g cosolvent, 240g emulsifier, 50g stabilizing agent and 5g acidity-basicity regulator successively, add the 435g deionized water after stirring again, continue to mix, leave standstill got final product in about 1 hour 15% eupatorium herb microemulsion.
Embodiment 4:
In the triangular flask of the 1000ml that agitator is housed, add the 100g solvent earlier, add 180g fragrant eupatorium herb extract again, stirring and dissolving is even, under agitation add 40g cosolvent, 240g emulsifier, 50g stabilizing agent and 5g acidity-basicity regulator successively, add the 385g deionized water after stirring again, continue to mix, leave standstill got final product in about 1 hour 18% eupatorium herb microemulsion.
Embodiment 5:
In the triangular flask of the 1000ml that agitator is housed, add the 150g solvent earlier, add 250g fragrant eupatorium herb extract again, stirring and dissolving is even, under agitation add 80g cosolvent, 200g emulsifier, 50g stabilizing agent and 5g acidity-basicity regulator successively, add the 265g deionized water after stirring again, continue to mix, leave standstill got final product in about 1 hour 25% eupatorium herb microemulsion.
Embodiment 6:
In the triangular flask of the 1000ml that agitator is housed, add the 100g solvent earlier, add 350g fragrant eupatorium herb extract again, stirring and dissolving is even, under agitation add 100g cosolvent, 200g emulsifier, 50g stabilizing agent and 5g acidity-basicity regulator successively, add the 195g deionized water after stirring again, continue to mix, leave standstill got final product in about 1 hour 35% eupatorium herb microemulsion.
Two, comparative example
Comparative example 1: wheat aphid control test
The Imidacloprid that adopts 1% eupatorium herb microemulsion, 1% fragrant eupatorium herb extract and 10% respectively compares test to the control of wheat aphid.
Test period: in May, 2006
Test site: Luyi County, Henan Province
Experimental condition: 1) 1% eupatorium herb microemulsion and 1% the contained former medicine of fragrant eupatorium herb extract are allied substances; 2) each handle to repeat 5 times, and wheat growing way of handling and repeating to select and the aphid situation that causes harm is roughly the same; 3) except that calculating scattering ratio and lethality, also added up the influence of medicament, calculated integrated control effect whole pest population.
Result of the test is as shown in table 1:
Table 1 wheat aphid is prevented and treated comparative trial
| For the examination agricultural chemicals | Extension rate | 3d scattering ratio or lethality (%) | 3d integrated control effect (%) | 5d scattering ratio or lethality (%) | 5d integrated control effect (%) |
| 1% eupatorium herb microemulsion, 1% fragrant eupatorium herb extract, 10% Imidacloprid | 100010001000 | 90.0178.0185.56 | 92.3181.1188.92 | 88.2275.4581.35 | 90.2376.3284.42 |
Result of the test shows, 1% eupatorium herb microemulsion is to the wheat aphid control efficiency, not only is better than 1% fragrant eupatorium herb extract and 10% Imidacloprid on the scattering ratio of three days and five days or lethality, and also is better than the two on integrated control effect.
Comparative example 2: lichee base of a fruit moth control test
The rotenone emulsifiable solution that adopts 18% eupatorium herb microemulsion, 18% fragrant eupatorium herb extract and 2.5% respectively compares test to the control of lichee base of a fruit moth.
Test period: in May, 2006
Test site: school district, Shenzhen Polytechnic east
Experimental condition: 1) 18% eupatorium herb microemulsion and 18% the contained former medicine of fragrant eupatorium herb extract are allied substances; 2) each handle to repeat 5 times, and the lichee age of tree of handling and repeating to select, kind, fruiting rate, the situation that causes harm are roughly the same; 3) except that calculating scattering ratio and lethality, also added up the influence of medicament, calculated integrated control effect whole pest population.
Result of the test is as shown in table 2:
Table 2 lichee base of a fruit moth prevents and treats comparative trial
| For the examination agricultural chemicals | Extension rate | 3d scattering ratio or lethality (%) | 3d integrated control effect (%) | 5d scattering ratio or lethality (%) | 5d integrated control effect (%) |
| The rotenone emulsifiable solution of the fragrant eupatorium herb extract 2.5% of 18% eupatorium herb microemulsion 18% | 100010001000 | 89.0175.6172.35 | 90.176.1374.92 | 88.2872.5471.53 | 89.3273.007232 |
Result of the test shows, 18% eupatorium herb microemulsion is to lichee base of a fruit moth control efficiency, not only on the scattering ratio of three days and five days or lethality, be better than 18% fragrant eupatorium herb extract and 2.5% rotenone emulsifiable solution, and on integrated control effect, also obviously be better than the two.
Comparative example 3: diamond-back moth control test
Adopt 35% eupatorium herb microemulsion, 35% fragrant eupatorium herb extract and 2.5% nimbin emulsion that the control of diamond-back moth is compared test respectively.
Test period: in May, 2006
Test site: Guangzhou Agricultural University Of South China farm
Experimental condition: 1) 35% eupatorium herb microemulsion and 35% the contained former medicine of fragrant eupatorium herb extract are allied substances; 2) each handle to repeat 5 times, handle and the wild cabbage growing way and the diamond-back moth situation that causes harm that repeat a little roughly the same; 3) except that calculating scattering ratio and lethality, also added up the influence of medicament, calculated integrated control effect whole pest population.
Result of the test is as shown in table 3:
Table 3 diamond-back moth prevents and treats comparative trial
| For the examination agricultural chemicals | Extension rate | 3d scattering ratio or lethality (%) | 3d integrated control effect (%) | 5d scattering ratio or lethality (%) | 5d integrated control effect (%) |
| 35% eupatorium herb microemulsion, 35% fragrant eupatorium herb extract, 2.5% nimbin emulsion | 100010001000 | 78.0172.9176.52 | 81.1074.4380.32 | 79.8269.8478.91 | 82.3971.2080.44 |
Result of the test shows, 35% eupatorium herb microemulsion is to the diamond-back moth control efficiency, not only on the scattering ratio of three days and five days or lethality, be better than 35% fragrant eupatorium herb extract and 2.5% nimbin emulsion, and on integrated control effect, also obviously be better than the two.
Claims (2)
1. an eupatorium herb microemulsion wherein contains fragrant eupatorium herb extract, solvent, cosolvent, emulsifier, stabilizing agent, water and acidity-basicity regulator, it is characterized in that, the shared mass percent composition of described each component is:
Fragrant eupatorium herb extract 0.01%～35%
Solvent 1%～35%
Cosolvent 0.5%～10%
Emulsifier 1%～35%
Stabilizing agent 0.5%～10%
Water 19.5%～95.5%
Acidity-basicity regulator 0.05%～10%;
Described fragrant eupatorium herb extract is:
The complete stool crushed material of A, fragrant eupatorium herb, with in methyl alcohol, ethanol, ethylene glycol, propyl alcohol, benzinum, chloroform, ethyl acetate, acetone, the cyclohexane a kind of, two or three, crushed material is soaked extraction 1～10 time, the ratio of crushed material and solvent can be 1: 1～1: 10, with extract be condensed into paste get final product the fragrant eupatorium herb extract; Or
B, with the paste among the A, with in methyl alcohol, ethanol, ethylene glycol, propyl alcohol, benzinum, chloroform, ethyl acetate, acetone, the cyclohexane a kind of, two or three, paste is extracted 1～10 time, the ratio of paste and solvent can be 1: 1～1: 10, with extract be condensed into paste get final product the fragrant eupatorium herb extract;
Described solvent is one or more the mixture that is selected from methyl alcohol, ethanol, ethylene glycol, propyl alcohol, benzinum, chloroform, ethyl acetate, acetone and the cyclohexane;
Described cosolvent is one or more the mixture that is selected from methyl alcohol, ethanol, acetone, isoamyl alcohol, butyl glycol ether, ethyl acetate, chloroform and the dimethyl sulfoxide (DMSO);
Described emulsifier is one or more the mixture that is selected from phenethyl phenol polyethenoxy ether, phenethyl phenol polyethenoxy polyethenoxy ether, polyoxyethylene nonylphenol ether, alkylphenol polyoxyethylene formaldehyde condensation products and the xenol APEO of alkyl benzene sulphonate sodium salt, alkylsurfuric acid sodium salt, styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether disulfonic acid magnesium salts, alkylammonium salt, triethanolamine salt, benzylbiphenyl phenol polyethenoxy ether, n=15～30;
Described stabilizing agent is one or more the mixture that is selected from 3-chloro-1,2 epoxy prapane, butyl glycidyl ether, phenyl glycidyl ether, methyl glycidyl ether, polyethylene glycol diglycidyl ether and the sodium sorbate;
Described acidity-basicity regulator is sodium hydroxide, ammoniacal liquor, acetic acid or hydrochloric acid.
2. the preparation method of an eupatorium herb microemulsion, it is characterized in that, at room temperature the extract with fragrant eupatorium herb under agitation adds dissolution with solvents in the described ratio of claim 1, the cosolvent, emulsifier, stabilizing agent, the acidity-basicity regulator that under agitation add the described ratio of claim 1 then successively, after treating that solution fully mixes, add entry again, mix, room temperature left standstill 1～5 hour, promptly.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102405743A (en) * | 2011-07-18 | 2012-04-11 | 广西壮族自治区中国科学院广西植物研究所 | Method for controlling and preventing intrusion of fragrant eupatorium herb |
| CN103444799A (en) * | 2013-09-10 | 2013-12-18 | 苏州莲花岛生态农业专业合作社 | Kongpo monkshood root plant based nano slow-release suspending agent |
| CN103444791A (en) * | 2013-09-10 | 2013-12-18 | 苏州市丰澄农业专业合作社 | Flanueria bidentis plant based nano slow-release oil suspending agent and preparation method thereof |
| CN103444802A (en) * | 2013-09-10 | 2013-12-18 | 苏州市丰澄农业专业合作社 | Pepper plant based nano slow-release suspending agent |
| CN103609599B (en) * | 2013-11-11 | 2015-10-28 | 宁波源丰消防设备有限公司 | A kind of Botanical herbicide powder and preparation method thereof |
| CN105053035B (en) * | 2015-08-10 | 2017-12-08 | 云南师范大学 | A kind of spacetabs type Eichhornia crassipes growth adjusting control agent and preparation method |
| CN106259513A (en) * | 2016-08-10 | 2017-01-04 | 吴远宁 | A kind of insecticide and preparation method thereof |
| CN106490072A (en) * | 2016-10-31 | 2017-03-15 | 郑州思辩科技有限公司 | A kind of botanical pesticide of preventing and treating buprestid beetle and preparation method thereof |
| CN108813619A (en) * | 2018-07-19 | 2018-11-16 | 广州市汉廷食品有限公司 | A kind of pollution-free food additive and its preparation process |
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Assignee: Shenzhenshi Huanong Biological Engineering Co., Ltd. Assignor: Shenzhen Polytechnic Contract record no.: 2010440020008 Denomination of invention: Eupatorium herb microemulsion and method for producing the same License type: Exclusive License Open date: 20080716 Record date: 20100322 |
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