CN101203481A - 三羟基多不饱和类花生酸衍生物 - Google Patents

三羟基多不饱和类花生酸衍生物 Download PDF

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Publication number
CN101203481A
CN101203481A CNA2006800180987A CN200680018098A CN101203481A CN 101203481 A CN101203481 A CN 101203481A CN A2006800180987 A CNA2006800180987 A CN A2006800180987A CN 200680018098 A CN200680018098 A CN 200680018098A CN 101203481 A CN101203481 A CN 101203481A
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CN
China
Prior art keywords
aryl
alkyl
formula
hydrogen
heteroaryl
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Pending
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CNA2006800180987A
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English (en)
Chinese (zh)
Inventor
N·A·佩塔西斯
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University of Southern California USC
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University of Southern California USC
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Publication of CN101203481A publication Critical patent/CN101203481A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/303—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by hydrogenation of unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C07F7/1872—Preparation; Treatments not provided for in C07F7/20
    • C07F7/1892—Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
CNA2006800180987A 2005-03-29 2006-03-28 三羟基多不饱和类花生酸衍生物 Pending CN101203481A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/093,757 US7582785B2 (en) 2002-04-01 2005-03-29 Trihydroxy polyunsaturated eicosanoid derivatives
US11/093,757 2005-03-29

Publications (1)

Publication Number Publication Date
CN101203481A true CN101203481A (zh) 2008-06-18

Family

ID=36645579

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2006800180987A Pending CN101203481A (zh) 2005-03-29 2006-03-28 三羟基多不饱和类花生酸衍生物

Country Status (9)

Country Link
US (1) US7582785B2 (https=)
EP (1) EP1863753B1 (https=)
JP (3) JP2008538117A (https=)
CN (1) CN101203481A (https=)
AU (1) AU2006230136B2 (https=)
BR (1) BRPI0609767A2 (https=)
CA (1) CA2603371C (https=)
MX (2) MX2007012022A (https=)
WO (1) WO2006105058A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103396350A (zh) * 2012-01-09 2013-11-20 浙江师范大学 一种利用顺式-1-卤-2-氯代烯烃合成维生素a的方法

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US7902257B2 (en) 2002-04-01 2011-03-08 University Of Southern California Trihydroxy polyunsaturated eicosanoid
US8481772B2 (en) 2002-04-01 2013-07-09 University Of Southern California Trihydroxy polyunsaturated eicosanoid derivatives
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103396350A (zh) * 2012-01-09 2013-11-20 浙江师范大学 一种利用顺式-1-卤-2-氯代烯烃合成维生素a的方法
CN103396350B (zh) * 2012-01-09 2014-11-05 浙江师范大学 一种利用顺式-1-卤-2-氯代烯烃合成维生素a的方法

Also Published As

Publication number Publication date
EP1863753A2 (en) 2007-12-12
AU2006230136B2 (en) 2011-11-03
MX352197B (es) 2017-11-13
CA2603371A1 (en) 2006-10-05
US7582785B2 (en) 2009-09-01
MX2007012022A (es) 2011-06-16
JP2012162576A (ja) 2012-08-30
JP2014122240A (ja) 2014-07-03
US20050228047A1 (en) 2005-10-13
EP1863753B1 (en) 2017-09-20
WO2006105058A2 (en) 2006-10-05
BRPI0609767A2 (pt) 2010-04-27
AU2006230136A1 (en) 2006-10-05
WO2006105058A3 (en) 2007-04-12
CA2603371C (en) 2013-05-28
JP2008538117A (ja) 2008-10-09

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