CN101189044B - 包含一种抗真菌剂以及一种选自丁香酚、麝香草酚和香芹酚的活性物质的药物组合物 - Google Patents

包含一种抗真菌剂以及一种选自丁香酚、麝香草酚和香芹酚的活性物质的药物组合物 Download PDF

Info

Publication number
CN101189044B
CN101189044B CN2006800164908A CN200680016490A CN101189044B CN 101189044 B CN101189044 B CN 101189044B CN 2006800164908 A CN2006800164908 A CN 2006800164908A CN 200680016490 A CN200680016490 A CN 200680016490A CN 101189044 B CN101189044 B CN 101189044B
Authority
CN
China
Prior art keywords
active substance
therapeutically active
carvacrol
fluconazole
eugenol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2006800164908A
Other languages
English (en)
Chinese (zh)
Other versions
CN101189044A (zh
Inventor
阿德南·雷梅尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADVENCED SCIENT DEVELOPEMENTS
Original Assignee
ADVENCED SCIENT DEVELOPEMENTS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADVENCED SCIENT DEVELOPEMENTS filed Critical ADVENCED SCIENT DEVELOPEMENTS
Publication of CN101189044A publication Critical patent/CN101189044A/zh
Application granted granted Critical
Publication of CN101189044B publication Critical patent/CN101189044B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41961,2,4-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN2006800164908A 2005-05-13 2006-05-15 包含一种抗真菌剂以及一种选自丁香酚、麝香草酚和香芹酚的活性物质的药物组合物 Expired - Fee Related CN101189044B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
WOPCT/IB2005/001317 2005-05-13
PCT/IB2005/001317 WO2006120496A1 (fr) 2005-05-13 2005-05-13 Combinaison pharmaceutique comprenant un agent antifongique et un actif choisi parmi le carveol, l’ eugenol, le thymol, le borneol, et le carvacrol
IBPCT/IB2005/001317 2005-05-13
PCT/IB2006/001329 WO2006120565A2 (fr) 2005-05-13 2006-05-15 Combinaison pharmaceutique comprenant un agent antifongique et un actif choisi parmi le carveol, l'eugenol, le thymol, le borneol, le carvacrol, et les i0n0nes alpha- et beta-.

Publications (2)

Publication Number Publication Date
CN101189044A CN101189044A (zh) 2008-05-28
CN101189044B true CN101189044B (zh) 2011-12-07

Family

ID=35427301

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2006800164908A Expired - Fee Related CN101189044B (zh) 2005-05-13 2006-05-15 包含一种抗真菌剂以及一种选自丁香酚、麝香草酚和香芹酚的活性物质的药物组合物

Country Status (13)

Country Link
US (1) US20080214568A1 (enExample)
EP (1) EP1879654B1 (enExample)
JP (1) JP5410747B2 (enExample)
CN (1) CN101189044B (enExample)
BR (1) BRPI0610132B8 (enExample)
CA (1) CA2607561C (enExample)
DK (1) DK1879654T3 (enExample)
EA (1) EA014068B1 (enExample)
ES (1) ES2390472T3 (enExample)
MA (1) MA29907B1 (enExample)
PT (1) PT1879654E (enExample)
TN (1) TNSN07425A1 (enExample)
WO (2) WO2006120496A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA200703385B (en) 2004-09-28 2008-09-25 Chemaphor Inc Compositions and methods for promoting weight gain and feed conversion
ES2716474T3 (es) * 2007-10-26 2019-06-12 Avivagen Inc Composiciones y métodos para mejorar la respuesta inmunitaria
WO2010124391A1 (en) 2009-04-30 2010-11-04 Chemaphor Inc. Methods and compositions for improving the health of animals
EP2480090B1 (en) 2009-09-24 2013-11-06 Unilever NV Disinfecting agent comprising eugenol, terpineol and thymol
WO2012076310A1 (en) 2010-12-07 2012-06-14 Unilever Nv An oral care composition
CN102550610B (zh) * 2010-12-07 2014-12-10 菲勒斯株式会社 含有从红松球果中提取的植物杀菌素的天然抗菌剂及包含它的水果病害防除原料
WO2012107252A2 (en) * 2011-02-07 2012-08-16 Firmenich Sa Antifungal flavouring ingredients and compositions
US9693941B2 (en) 2011-11-03 2017-07-04 Conopco, Inc. Liquid personal wash composition
JP5925605B2 (ja) * 2012-06-04 2016-05-25 花王株式会社 リパーゼ活性阻害剤、抗真菌剤、及びフケ抑制剤
CA2963923A1 (en) 2014-10-08 2016-04-14 Pacific Northwest Research Institute Methods and compounds for increasing the potency of antifungal agents
CN104642326B (zh) * 2015-02-16 2016-02-10 河南科技学院 一种含戊苯吡菌胺和香芹酚的杀菌组合物及其用途
WO2017209588A2 (fr) 2016-06-02 2017-12-07 Advanced Scientific Developements Formulation pharmaceutique de cinéol et d'amoxicilline
US10918647B2 (en) 2016-07-26 2021-02-16 University Of Southern California Selective bromodomain inhibition of fungal Bdf1
CN113116916B (zh) * 2021-05-25 2023-07-04 河北医科大学第二医院 一种治疗妇科疾病的药物组合物及其制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5294645A (en) * 1993-06-14 1994-03-15 Doyle E. Chastain Using menth-1-en-9-ol to kill bacteria, yeast, and fungi
CA2106032C (en) * 1993-09-13 1995-11-07 Gamini Weeratunga Methods for the manufacture of fluconazole and forms thereof, intermediates useful in the manufacture thereof, and combinations comprising fluconazole
CN1112933C (zh) * 1994-01-14 2003-07-02 爱克索马技术有限公司 抗真菌的方法和物质
CA2224227A1 (en) * 1995-06-07 1996-12-19 Avmax, Inc. Use of essential oils to increase bioavailability of oral pharmaceutical compounds
US6319507B1 (en) * 1997-05-02 2001-11-20 Kobo Products, Inc. Agar gel bead composition and method
US6414036B1 (en) * 1999-09-01 2002-07-02 Van Beek Global/Ninkov Llc Composition for treatment of infections of humans and animals
AU2002217316A1 (en) * 2001-01-03 2002-07-30 Medpharma Plc Use of terpenes for the treatment of digestive tract infections
JP2002284702A (ja) * 2001-01-19 2002-10-03 Teika Seiyaku Kk 外用抗真菌製剤
US20030064948A1 (en) * 2001-02-08 2003-04-03 Alfred Fahr Invasomes for therapy of disorders, their preparation and use
JP2002363070A (ja) * 2001-06-06 2002-12-18 Yuutoku Yakuhin Kogyo Kk 経皮吸収貼付剤
US20040071757A1 (en) * 2001-11-20 2004-04-15 David Rolf Inhalation antiviral patch
US20030180349A1 (en) * 2001-12-07 2003-09-25 Franklin Lanny U. Respiratory infection prevention and treatment with terpene-containing compositions
US20030225003A1 (en) * 2002-04-18 2003-12-04 Dusan Ninkov Antimicrobial therapeutic compositions for oral and topical use
US20040151771A1 (en) * 2003-02-04 2004-08-05 Gin Jerry B. Long-lasting, flavored dosage forms for sustained release of beneficial agents within the mouth
WO2004089357A2 (en) * 2003-04-02 2004-10-21 Regents Of The University Of Minnesota Anti-fungal formulation of triterpene and essential oil

Also Published As

Publication number Publication date
US20080214568A1 (en) 2008-09-04
BRPI0610132B1 (pt) 2020-08-11
PT1879654E (pt) 2012-08-29
DK1879654T3 (da) 2012-08-20
WO2006120565A2 (fr) 2006-11-16
CA2607561A1 (fr) 2006-11-16
EA014068B1 (ru) 2010-08-30
BRPI0610132B8 (pt) 2021-05-25
CA2607561C (fr) 2014-02-04
MA29907B1 (fr) 2008-11-03
WO2006120565A3 (fr) 2007-08-23
CN101189044A (zh) 2008-05-28
WO2006120496A1 (fr) 2006-11-16
ES2390472T3 (es) 2012-11-13
JP5410747B2 (ja) 2014-02-05
TNSN07425A1 (fr) 2009-03-17
JP2008540506A (ja) 2008-11-20
BRPI0610132A2 (pt) 2012-09-25
EA200702482A1 (ru) 2008-04-28
EP1879654A2 (fr) 2008-01-23
EP1879654B1 (fr) 2012-07-04

Similar Documents

Publication Publication Date Title
CN101189044B (zh) 包含一种抗真菌剂以及一种选自丁香酚、麝香草酚和香芹酚的活性物质的药物组合物
Malani et al. Changing epidemiology of rare mould infections: implications for therapy
Boucher et al. Newer systemic antifungal agents: pharmacokinetics, safety and efficacy
Kauffman et al. Update on echinocandin antifungals
JP2013535422A5 (enExample)
WO2023246487A1 (zh) 一种抗真菌药物增效剂
Spencer et al. Systemic fungal infections: A pharmacist/researcher perspective
Alharbi et al. High molecular weight hyaluronic acid reduces the growth and biofilm formation of the oral pathogen Porphyromonas gingivalis
Girardot et al. Novel strategies against Candida biofilms: interest of synthetic compounds
CN106390130A (zh) 烟酰胺作为抗真菌药物增效剂的用途
CN107073124A (zh) 增效的抗微生物剂
CN101522195A (zh) 含有苯基脒衍生物的药物组合物和该药物组合物与抗真菌剂的联合使用方法
Girmenia et al. Fluconazole in combination with flucytosine in the treatment of fluconazole-resistant Candida infections
Li et al. Drug Clues for the Treatment of Fungal Catheter-Related Bloodstream Infection With Antifungal Lock Therapy
US6660761B2 (en) Method of treatment for fungal infections with a synergistic formulation of antifungal agents
Zaas et al. Micafungin: the US perspective
CN116808055B (zh) 一种香紫苏内酯和两性霉素b联合抗新型隐球菌的方法
US20220160631A1 (en) Antifungal nanoparticles for targeted treatment of fungal infections
CN113332277B (zh) 一种吡咯二酮化合物在制备抗真菌药物中的应用
Shirsat et al. Review on antifungal agents
Sharma et al. A short review on liquisolid technology in anti-fungal drugs: https://doi. org/10.54037/WJPS. 2022.100116
US20240156795A1 (en) Methods and compositions for the treatment of drug resistant topical infections
CA2479381C (en) A use of treatment for fungal infections with a synergistic formulation of antifungal agent, menthol and menthyl acetate
CN100469392C (zh) 抗真菌药物组合物
ES2732941T3 (es) Oleilfosfocolina para el tratamiento de la micosis

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20111207

Termination date: 20210515