CN101167906A - Medicinal composition for reducing blood lipid and reducing weight and preparation process thereof - Google Patents
Medicinal composition for reducing blood lipid and reducing weight and preparation process thereof Download PDFInfo
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- CN101167906A CN101167906A CNA2007101772998A CN200710177299A CN101167906A CN 101167906 A CN101167906 A CN 101167906A CN A2007101772998 A CNA2007101772998 A CN A2007101772998A CN 200710177299 A CN200710177299 A CN 200710177299A CN 101167906 A CN101167906 A CN 101167906A
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Abstract
The invention discloses a medicament composition for decreasing and reducing fat, which comprises twelve parts of traditional Chinese medicines of haw, rhizoma alismatis, radix salvia miltiorrhiza, astragalus root, rhubarb horsetails, tetrandra root, bighead atractylodes rhizome, fleece-flower root, cassia seed, chuanxiong rhizome, lotus leaf, citrus reticulata blanco and the like. The medicament composition of the invention is capable of reinforcing vital energy and enlivening the spleen, activating blood circulation and removing stasis, relieving stuffiness of the chest and reducing mass, reducing body weight and decreasing fat, further the invention is used for simple obesity. The effect is obvious and the production the simple, thereby the invention has an extensive application value.
Description
Technical field
Belong to Chinese medicine preparation technique field, a kind of specifically Chinese medicine preparation that is used for the human body weight-losing blood fat reducing and preparation method thereof.
Background technology
WHO formally was decided to be obesity a kind of disease in 1997, obesity was classified as the third-largest chronic killer who is only second to smoking and acquired immune deficiency syndrome (AIDS).China's problem of obesity is severe day by day, overweight and fat crowd increases very fast, during national nutrition survey in 1992, Body Mass Index (BMI) 〉=25 accounted for 14% in 20～74 years old, the data sink bulk analysis nineties in 20th century shows that China overweight person that is grown up is 24.4%, the overweight people accounts for 3.01%, and overweight ratio with obesity is 8: 1, and the potential speed of its growth will be very fast.Because fat and relevant disease healthhazard own, obesity can be damaged patient's physical and mental health, and quality of life descends, and life expectancy shortens.The fat worry of not only bringing self form to people, and can cause diseases such as coronary heart disease, apoplexy because the increase of body weight cause the cardiac function over loading.Obesity becomes one of important worldwide health problem gradually, and under the leader of Ministry of Public Health Department of Disease Control, in April, 2003, China worked out " the overweight and obesity prevention and control guide of China adult ".
The medical worker is just attempting to study various methods of weight-reducing, but poor effect often, and some chemical drugss have certain liver toxicity more, the patient usually faces Weight-reducing and lipid-lowering and the conflicting predicament of liver protecting therapy.In recent years, some prepare Chinese medicine and carry out Weight-reducing and lipid-lowering, and as " a kind of Weight-reducing and lipid-lowering Chinese medicine preparation " that the CN1424102A patent application proposes, it is the capsule by 16 kinds of Chinese medicine preparations such as Radix Stephaniae Tetrandrae, Rhizoma Alismatis, Semen Sinapis Albae, Semen Persicae, Exocarpium Benincasae.And for example " the fat-reducing Chinese medicine of treatment Simple Obesity " of CN1565554A patent application proposition is the preparation by Folium Nelumbinis, Fructus Crataegi, Semen Cassiae, Folium Camelliae sinensis, Flos Lonicerae preparation.Different Chinese medicine preparations, the slimming preparation effect that makes has marked difference.
Summary of the invention
The objective of the invention is to overcome present weak point, provide a kind of evident in efficacy, convenience of drawing materials, the pharmaceutical composition of the treatment Simple Obesity that expense is cheap, side effect is little in the treatment Simple Obesity.
The present invention also provides this preparation method of Chinese medicine.
Pharmaceutical composition of the present invention can be used for Simple Obesity.
Chinese medicine of the present invention is prepared from by the following weight parts proportion raw material:
150～400 parts of 300～700 parts of Radix Salviae Miltiorrhizaes of 300～700 portions of Rhizoma Alismatis of Fructus Crataegi
150～400 parts of 80～200 parts of Radixs Stephaniae Tetrandrae of 300～700 parts of Radix Et Rhizoma Rhei of the Radix Astragali
80～200 parts of 80～200 parts of Semen Cassiaes of 150～400 parts of Radixs Polygoni Multiflori of the Rhizoma Atractylodis Macrocephalae
80～200 parts of 80～200 parts of Pericarpium Citri Reticulataes of 80～200 parts of Folium Nelumbinis of Rhizoma Chuanxiong
Chinese medicine of the present invention is prepared from by the following weight parts proportion raw material:
200～300 parts of 400～600 parts of Radix Salviae Miltiorrhizaes of 400～600 portions of Rhizoma Alismatis of Fructus Crataegi
200～300 parts of 100～150 parts of Radixs Stephaniae Tetrandrae of 400～600 parts of Radix Et Rhizoma Rhei of the Radix Astragali
100～150 parts of 100～150 parts of Semen Cassiaes of 200～300 parts of Radixs Polygoni Multiflori of the Rhizoma Atractylodis Macrocephalae
100～150 parts of 100～150 parts of Pericarpium Citri Reticulataes of 100～150 parts of Folium Nelumbinis of Rhizoma Chuanxiong
Chinese medicine of the present invention is prepared from by following optimum weight part proportion raw material:
125 parts of 500 parts of Radix Et Rhizoma Rhei of 250 parts of Radixs Astragali of 500 parts of Radix Salviae Miltiorrhizaes of 500 portions of Rhizoma Alismatis of Fructus Crataegi
125 parts of 125 parts of Rhizoma Chuanxiongs of 125 parts of Semen Cassiaes of 250 parts of Radixs Polygoni Multiflori of 250 parts of Rhizoma Atractylodis Macrocephalaes of Radix Stephaniae Tetrandrae
125 parts of 125 parts of Pericarpium Citri Reticulataes of Folium Nelumbinis
Chinese medicine of the present invention can be prepared from by following method:
1, described medicine is respectively got 10～30% and is ground into superfine powder, and is standby.
2, other 70～90% medicine decocts with water twice, and 0.5～4 hour for the first time, 0.5～3 hour for the second time.
3, collecting decoction concentrates, and adds (1) Chinese medicine powder, spray drying, encapsulated getting final product.
Wherein said Fructus Crataegi is the dry mature fruit of rosaceous plant Fructus Pyri Pashiae Crataegus pinnatifida Bge.var.majorN.E.Br. or Fructus Crataegi Crataegus pinnatifida Bge..Main product in Shandong, Henan, Jiangsu, zhejiang and other places.With Fructus Crataegi is good.
Rhizoma Alismatis is the dry tuber of Alismataceae plant Rhizoma Alismatis Alisma orientalis (Sam.) Juzep..Main product is in Sichuan, Fujian and other places.With Rhizoma Alismatis is good.
Radix Salviae Miltiorrhizae is the dry root and rhizome of labiate Radix Salviae Miltiorrhizae Salvia miltiorrhiza Bge..Main product in Sichuan, Shandong, zhejiang and other places.
The Radix Astragali is the root of leguminous plant Radix Astagali Astragalus membranaceus Bge.var.mongholicus (Bge.) Hsiao.Main product in the Inner Mongol, ground such as Shanxi and Heilungkiang.With Radix Astragali Preparata is good.
Radix Et Rhizoma Rhei is the dry root and rhizome of polygonum rheum palmatum Rheum palmatum L., Rheum tanguticum Rheumtanguticum Maxim.ex Balf. or Rheum officinale Rheum officinale Baill..Main product in Hubei, ground such as Sichuan, Yunnan, Guizhou.With Radix Et Rhizoma Rhei is good.
Radix Stephaniae Tetrandrae is the dry root of menispermaceous plants Radix stephaniae tetrandrae Stephania tetrandra S.Moore.Main product in Zhejiang, ground such as Anhui, Hubei, Hunan, Jiangxi.With Radix stephaniae tetrandrae is good.
The Rhizoma Atractylodis Macrocephalae is the dry rhizome of feverfew Rhizoma Atractylodis Macrocephalae Atractylodes macrocephala Koidz..Main product in Zhejiang, ground such as Hunan, Hubei, Hebei, Shandong.With Rhizoma Atractylodis Macrocephalae (parched with bran) is good.
The Radix Polygoni Multiflori is the dried root of polygonum multiflorum thunb Polygonum multiflorum Thunb..Main product is in China North China, northwest, southwest and other places.With Radix Polygoni Multiflori is good.
Semen Cassiae is the dry mature seed of Semen Cassiae Cassia obtusifolia L. of leguminous herbaceous plant or little Semen Cassiae Cassia tora L..Main product in Anhui, ground such as Jiangsu, Zhejiang, Sichuan.
Rhizoma Chuanxiong is the dry rhizome of samphire Rhizoma Chuanxiong Ligusticum chuanxiong Hort..Be distributed in ground such as Sichuan, Guizhou, Yunnan.
Folium Nelumbinis is the dried leaves of nymphaeaceae plant lotus Nelumbo nucifera Gaertn..Main product in the Hunan, ground such as Hubei, Zhejiang, Jiangsu.
Pericarpium Citri Reticulatae is the dry mature skin of rutaceae orange Citrus reticulata Blanco. and variety thereof.Main product in Guangdong, ground such as Guangxi, Fujian, Jiangxi.To fry Pericarpium Citri Reticulatae is good.
Fructus Crataegi, Rhizoma Alismatis are monarch in the prescription of the present invention.Fructus Crataegi spleen invigorating removing food stagnancy is eaten dissipating blood stasis clearly.Modern medicine proves that Fructus Crataegi contains citric acid, malic acid, ascorbic acid, candy and protein, carbohydrate, and the effect that promotes gastro-intestinal digestion is arranged.The Rhizoma Alismatis diuresis, clearing away damp-heat.Experimentation shows, Rhizoma Alismatis can reduce fat index and serum triglycerides content around Lee index, uterus and the testis of sodium glutamate obese rat, has the effect of Weight-reducing and lipid-lowering.
The Radix Stephaniae Tetrandrae diuretic that dispels the wind; Radix Astragali benefiting QI for strengthening the superficies, inducing diuresis to remove edema; Rhizoma Atractylodis Macrocephalae air making-up and spleen enlivening, transmitting and distributing the fluids.Three medicines are combined into Tetrandra and Astragalus Decoction, and the replenishing QI to invigorate the spleen diuretic helps the merit of Fructus Crataegi, Rhizoma Alismatis spleen invigorating removing food stagnancy, is ministerial drug.
The Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, lowering blood-fat and reducing weight.Radix Et Rhizoma Rhei, Radix Polygoni Multiflori energy stasis removing, blood circulation promoting and blood stasis dispelling.Enterokinesia is increased, promote the drainage of triglyceride, fatty cholesterol, reduce the absorption of fatty cholesterol and the tool fat-reducing and antihyperglycemic can also promote bile secretion, and the content of bile mesobilirubin and bile acid is increased, help digesting and assimilating of fat.The Semen Cassiae loosening bowel to relieve constipation, lipid-lowering weight-reducing.Rhizoma Chuanxiong activating QI to alleviate the depression, promoting blood circulation and stopping pain, dispeiling pathogenic wind and removing dampness, grease removal fat-reducing.Radix Salviae Miltiorrhizae, Radix Et Rhizoma Rhei, the Radix Polygoni Multiflori, Semen Cassiae, Rhizoma Chuanxiong are adjuvant drug.
The Folium Nelumbinis relieving restlessness is quenched the thirst, Weight-reducing and lipid-lowering; The Pericarpium Citri Reticulatae the chest stuffiness relieving removing food stagnancy of regulating the flow of vital energy.Be messenger drug.
All medicines share, and play replenishing QI to invigorate the spleen, blood circulation promoting and blood stasis dispelling, the chest stuffiness relieving altogether and go the merit of blood fat reducing of amassing, make light of one's life by commiting suicide.
Beneficial effect of the present invention is:
1, selecting Chinese crude drug for use is raw material, and each component meets the pharmaceutical control and administration rules, utilizes the comprehensive function of the Chinese medicine of respectively distinguishing the flavor of to treat Simple Obesity, gives full play to the little advantage of herbal toxic effect, nontoxic, can take for a long time.
2, the present invention need not to decoct no bitterness sense, taking convenience.
3, the present invention is cheap.
Clinical observation shows with these invention treatment Simple Obesity 156 examples, total effective rate 84.62%.Do blood, urine, just routine and hepatic and renal function inspection before and after the treatment, no abnormality seen changes, and does not find in the medication process that this medicine has tangible untoward reaction.Test shows that this invention treatment Simple Obesity is evident in efficacy, has no side effect.
Specific embodiment one
Fructus Crataegi 400g Rhizoma Alismatis 400g Radix Salviae Miltiorrhizae 200g Radix Astragali 400g Radix Et Rhizoma Rhei 100g Radix Stephaniae Tetrandrae 200g
Rhizoma Atractylodis Macrocephalae 200g Radix Polygoni Multiflori 100g Semen Cassiae 100g Rhizoma Chuanxiong 100g Folium Nelumbinis 100g Pericarpium Citri Reticulatae 125g
Above-mentioned medicine is respectively got 30% and is ground into superfine powder, and is standby.Other 70% medicine decocts with water twice, and 0.5～4 hour for the first time, 0.5～3 hour for the second time.Collecting decoction concentrates, and adds the drug powder of porphyrize, spray drying, encapsulated getting final product.Every capsules 0.5g.
Specific embodiment two
Fructus Crataegi 600g Rhizoma Alismatis 600g Radix Salviae Miltiorrhizae 300g Radix Astragali 600g Radix Et Rhizoma Rhei 150g Radix Stephaniae Tetrandrae 300g
Rhizoma Atractylodis Macrocephalae 300g Radix Polygoni Multiflori 150g Semen Cassiae 150g Rhizoma Chuanxiong 150g Folium Nelumbinis 150g Pericarpium Citri Reticulatae 150g
Above-mentioned medicine is respectively got 10% and is ground into superfine powder, and is standby.Other 90% medicine decocts with water twice, and 0.5～4 hour for the first time, 0.5～3 hour for the second time.Collecting decoction concentrates, and adds the drug powder of porphyrize, spray drying, encapsulated getting final product.Every capsules 0.5g.
Specific embodiment three
Fructus Crataegi 500g Rhizoma Alismatis 500g Radix Salviae Miltiorrhizae 250g Radix Astragali 500g Radix Et Rhizoma Rhei 125g Radix Stephaniae Tetrandrae 250g
Rhizoma Atractylodis Macrocephalae 250g Radix Polygoni Multiflori 125g Semen Cassiae 125g Rhizoma Chuanxiong 125g Folium Nelumbinis 125g Pericarpium Citri Reticulatae 125g
Above-mentioned medicine is respectively got 20% and is ground into superfine powder, and is standby.Other 80% medicine decocts with water twice, and 0.5～4 hour for the first time, 0.5～3 hour for the second time.Collecting decoction concentrates, and adds the drug powder of porphyrize, spray drying, encapsulated getting final product.Every capsules 0.5g.
Claims (4)
1. the pharmaceutical composition of a lowering blood-fat and reducing weight is characterized in that raw material contains following medicaments in part by weight: 300～700 parts of Fructus Crataegis, 300～700 parts of Rhizoma Alismatis, 150～400 parts of Radix Salviae Miltiorrhizaes, 300～700 parts of the Radixs Astragali, 80～200 parts of Radix Et Rhizoma Rhei, 150～400 parts of Radixs Stephaniae Tetrandrae, 150～400 parts of the Rhizoma Atractylodis Macrocephalaes, 80～200 parts of the Radixs Polygoni Multiflori, 80～200 parts of Semen Cassiaes, 80～200 parts of Rhizoma Chuanxiongs, 80～200 parts on Folium Nelumbinis, 80～200 parts of Pericarpium Citri Reticulataes.
2. require described pharmaceutical composition according to right 1, it is characterized in that raw material contains following medicaments in part by weight: 400～600 parts of Fructus Crataegis, 400～600 parts of Rhizoma Alismatis, 200～300 parts of Radix Salviae Miltiorrhizaes, 400～600 parts of the Radixs Astragali, 100～150 parts of Radix Et Rhizoma Rhei, 200～300 parts of Radixs Stephaniae Tetrandrae, 200～300 parts of the Rhizoma Atractylodis Macrocephalaes, 100～150 parts of the Radixs Polygoni Multiflori, 100～150 parts of Semen Cassiaes, 100～150 parts of Rhizoma Chuanxiongs, 100～150 parts on Folium Nelumbinis, 100～150 parts of Pericarpium Citri Reticulataes.
3. require the pharmaceutical composition of described a kind of lowering blood-fat and reducing weight according to right 1,2, it is characterized in that the optimised quantity of each raw material is: 500 parts of Fructus Crataegis, 500 parts of Rhizoma Alismatis, 250 parts of Radix Salviae Miltiorrhizaes, 500 parts of the Radixs Astragali, 125 parts of Radix Et Rhizoma Rhei, 250 parts of Radixs Stephaniae Tetrandrae, 250 parts of the Rhizoma Atractylodis Macrocephalaes, 125 parts of the Radixs Polygoni Multiflori, 125 parts of Semen Cassiaes, 125 parts of Rhizoma Chuanxiongs, 125 parts on Folium Nelumbinis, 125 parts of Pericarpium Citri Reticulataes.
4. require described medicine according to right 3, get 10～30% and be ground into superfine powder, standby.Other 70～90% medicine decocts with water twice, and 0.5～4 hour for the first time, 0.5～3 hour for the second time.Collecting decoction concentrates, and adds ground traditional Chinese medicine thing powder, spray drying, encapsulated getting final product.
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Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101417056B (en) * | 2008-12-09 | 2011-01-12 | 赵玉红 | Traditional Chinese medicine decoction for treating obesity |
| CN101417063B (en) * | 2008-12-10 | 2011-03-16 | 张春秀 | Oral traditional Chinese medicine for treating obesity |
| CN101417058B (en) * | 2008-12-10 | 2011-04-27 | 逯传玲 | Traditional Chinese medicine combination for treating obesity |
| CN102526436A (en) * | 2012-02-16 | 2012-07-04 | 朱剑萍 | Slimming capsule and preparation method and application thereof |
| CN104431178A (en) * | 2014-12-09 | 2015-03-25 | 湖南科技大学 | Health tea for reducing fat and losing weight |
| CN104666660A (en) * | 2013-11-28 | 2015-06-03 | 天津瑞贝特科技发展有限公司 | Traditional Chinese medicine composition capable of enhancing disease resistance of wild pigs and reducing fat content and preparation method thereof |
| CN104689158A (en) * | 2015-04-09 | 2015-06-10 | 李汶峰 | Traditional Chinese medicine for weight losing |
| CN105327280A (en) * | 2015-11-28 | 2016-02-17 | 青岛麦瑞特医药技术有限公司 | Traditional Chinese medicine composition for treating pure obesity and preparation method thereof |
| CN106177022A (en) * | 2016-08-17 | 2016-12-07 | 施泽晶 | A kind of Chinese medicine composition of lowering blood-fat and reducing weight and preparation method thereof |
| CN107114514A (en) * | 2017-06-01 | 2017-09-01 | 湖北民族学院 | A kind of heat-clearing Antilipemic slimming tea and preparation method thereof |
| CN107519275A (en) * | 2017-06-28 | 2017-12-29 | 邢侠 | Chinese medicine composition for lowering blood-fat and reducing weight and preparation method thereof |
| CN108186886A (en) * | 2018-03-01 | 2018-06-22 | 烟台新时代健康产业有限公司 | A kind of pharmaceutical composition and its pharmaceutical preparation with functions of lowering blood-fat and reducing weight |
| CN108323609A (en) * | 2018-04-23 | 2018-07-27 | 娄海山 | Invigorating the spleen health protection tea |
| CN108404055A (en) * | 2018-05-23 | 2018-08-17 | 重庆医药高等专科学校 | Chinese medicine composition for weight-reducing |
| CN109007187A (en) * | 2018-09-26 | 2018-12-18 | 北京中医药大学 | Lipid-lowering health-care tea and preparation method thereof |
| CN109847027A (en) * | 2019-03-25 | 2019-06-07 | 江西中医药大学 | A kind of preparation process of Guben Huatan Chinese traditional medicines depressing lipid composition and its preparation |
| CN109893643A (en) * | 2019-03-19 | 2019-06-18 | 南京星银药业集团有限公司 | A kind of composition and preparation method thereof for treating obesity |
| CN112336803A (en) * | 2020-11-05 | 2021-02-09 | 王大伟 | Traditional Chinese medicine weight-losing formula |
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Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101417056B (en) * | 2008-12-09 | 2011-01-12 | 赵玉红 | Traditional Chinese medicine decoction for treating obesity |
| CN101417063B (en) * | 2008-12-10 | 2011-03-16 | 张春秀 | Oral traditional Chinese medicine for treating obesity |
| CN101417058B (en) * | 2008-12-10 | 2011-04-27 | 逯传玲 | Traditional Chinese medicine combination for treating obesity |
| CN102526436A (en) * | 2012-02-16 | 2012-07-04 | 朱剑萍 | Slimming capsule and preparation method and application thereof |
| CN104666660A (en) * | 2013-11-28 | 2015-06-03 | 天津瑞贝特科技发展有限公司 | Traditional Chinese medicine composition capable of enhancing disease resistance of wild pigs and reducing fat content and preparation method thereof |
| CN104431178A (en) * | 2014-12-09 | 2015-03-25 | 湖南科技大学 | Health tea for reducing fat and losing weight |
| CN104689158A (en) * | 2015-04-09 | 2015-06-10 | 李汶峰 | Traditional Chinese medicine for weight losing |
| CN105327280A (en) * | 2015-11-28 | 2016-02-17 | 青岛麦瑞特医药技术有限公司 | Traditional Chinese medicine composition for treating pure obesity and preparation method thereof |
| CN106177022A (en) * | 2016-08-17 | 2016-12-07 | 施泽晶 | A kind of Chinese medicine composition of lowering blood-fat and reducing weight and preparation method thereof |
| CN107114514A (en) * | 2017-06-01 | 2017-09-01 | 湖北民族学院 | A kind of heat-clearing Antilipemic slimming tea and preparation method thereof |
| CN107519275A (en) * | 2017-06-28 | 2017-12-29 | 邢侠 | Chinese medicine composition for lowering blood-fat and reducing weight and preparation method thereof |
| CN108186886A (en) * | 2018-03-01 | 2018-06-22 | 烟台新时代健康产业有限公司 | A kind of pharmaceutical composition and its pharmaceutical preparation with functions of lowering blood-fat and reducing weight |
| CN108323609A (en) * | 2018-04-23 | 2018-07-27 | 娄海山 | Invigorating the spleen health protection tea |
| CN108404055A (en) * | 2018-05-23 | 2018-08-17 | 重庆医药高等专科学校 | Chinese medicine composition for weight-reducing |
| CN109007187A (en) * | 2018-09-26 | 2018-12-18 | 北京中医药大学 | Lipid-lowering health-care tea and preparation method thereof |
| CN109893643A (en) * | 2019-03-19 | 2019-06-18 | 南京星银药业集团有限公司 | A kind of composition and preparation method thereof for treating obesity |
| CN109847027A (en) * | 2019-03-25 | 2019-06-07 | 江西中医药大学 | A kind of preparation process of Guben Huatan Chinese traditional medicines depressing lipid composition and its preparation |
| CN112336803A (en) * | 2020-11-05 | 2021-02-09 | 王大伟 | Traditional Chinese medicine weight-losing formula |
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