CN101156598B - Mould inhibitor with mildew resistant and mold toxin adsorption dual behavior as well as preparation method - Google Patents
Mould inhibitor with mildew resistant and mold toxin adsorption dual behavior as well as preparation method Download PDFInfo
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- CN101156598B CN101156598B CN2007100532821A CN200710053282A CN101156598B CN 101156598 B CN101156598 B CN 101156598B CN 2007100532821 A CN2007100532821 A CN 2007100532821A CN 200710053282 A CN200710053282 A CN 200710053282A CN 101156598 B CN101156598 B CN 101156598B
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- mould inhibitor
- propionate
- silicate
- alumino
- acid
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Abstract
The invention discloses mould inhibitor with double adsorption functions of mould inhibitor and thenystatin, and the preparation method thereof. The mould inhibitor is compounded by sillico aluminate, propionate, organic acid, and monoprop in a certain proportion. The invention has the preparing procedure that: firstly, hydration silicon aluminate is selected for being pulverized by a ball mill pulverizer and being filtered by a screen; secondly, the hydration silicon aluminate ore powder is soaked in equal-volume hydrochloric acid under the normal temperature, and the agglomerated powder is rotated; finally, the propionate and the organic acid in proportion is added and stirred, and the monoprop is added, after being mixed evenly, the mould inhibitor is made. The product of the invention is effective, safe, and pollution-free, has better economic benefit and social benefit with high performance price ratio, and the prospect of the application is broad.
Description
Technical field
The present invention relates to the feed safety technical field, more specifically relate to a kind of mould inhibitor, also relate to the preparation method of this mould inhibitor simultaneously with mildew-resistant and mycotoxin adsorption dual effect.This mould inhibitor can effectively solve feed mold and the mould contamination in feed production and the storage process, guarantees feed quality and animal health, reduces antibioticly to use and to the pollution of environment, especially the aflatoxin B1 adsorption rate is reached 80%.
Background technology
The ratio that China's feed industry is subjected to mould contamination is bigger, and nearly have 20% feed is caused waste by mould contamination.The main harm of mould is that the exotoxin and the endotoxin of its generation can cause the animal body function to produce bad reaction.Mycotoxin is the metabolite of mould, it is the secondary metabolic product that is produced after mould grows on various organic matter with toxicity, from the testing result of the feed that goes mouldy in a large number at present, main mycotoxin is AFB1, vomitoxin, zearalenone etc. in the feed.These toxin are more common in the middle of feed, and also bigger for the animal body influence.Particularly some toxin is easy to cause the death of animal body for some animal comparison sensitivities.
At feed mold, a lot of feed workers have taked interpolation mould inhibitor and methods such as improving the feed storage condition to control, and have obtained certain effect.But how wet China's summer climate high temperature is, even particularly southern area has taked these methods the phenomenon of feed mold still can occur.In order to eliminate inevitable toxin, a lot of scholars adopt some materials to handle the feed that goes mouldy as the adsorbent of mycotoxin, and these materials mainly are divided into two kinds of hydrated aluminum silicate class and non-hydrated aluminum silicates at present.
The non-hydrated aluminum silicate mainly adopts chemical substances such as sodium hydroxide, ammonia, clorox, chlorine that the feed that goes mouldy is handled, and toxin is decomposed, to reduce toxicity.But this method shortcoming is that cost is higher, operating difficulties, and particularly nutriment is understood destroyed and the nutritive value of feed and palatability is reduced when handling, and therefore can't adopt in the production of feed.Also have part Study person to utilize to have some specific microorganisms to degrade the mycotoxin that goes mouldy in the feed, but this method operating difficulties on existing research level, cost is higher, still can't reach industrialization phase.
Natural aluminosilicate such as zeolite, montmorillonite, diatomite, kaolin etc. because have bigger specific surface area and ion adsorption capacity, have certain selection adsorption capacity and cause researcher's interest mycotoxin.Studies show that in a large number, aluminum silicate surface group or distribution of charges are carried out can making the material of new formation obtain new physicochemical characteristics, thereby improving its adsorption capacity to other mycotoxin after the suitable modification.After if you would taking off stone process cetyl pyridinium or the processing of cetyl trimethylammonium, the montmorillonite mineral surface descends to the affinity of water, hydrophobic performance improves, so hydrophobic zearalenone is had higher affinity, the adsorption capacity of zearalenone is improved greatly.
Chinese patent publication number CN1843151 discloses a kind of " composite mold toxin sorbent ", and this adsorbent comprises hydrated aluminosilicate, and weight content is 15-85%; Yeast cell wall, weight content are 5-50% weter hyacinth root powder, and weight content is compositions such as 5-50%; The method that adopts conventional drying, pulverizes and sieve is composited.This composite mold toxin sorbent can effectively reduce the multiple mycotoxin in the feed, particularly Chinese common mycotoxins such as AFB1, ochratoxin A, zearalenone, zearalenol, vomitoxin is had the good adsorption performance.Adopt yeast cell wall in this adsorbent prescription, though the special construction of yeast cell wall produces absorption affinity to mycotoxin, the complex manufacturing of yeast cell wall, the unit cost height has improved the cost of product greatly, is unfavorable for that scale uses.
The safety issue of feed becomes the focus that people pay close attention to gradually at present, and feed safety directly influences the safety of food.Mould inhibitor of the present invention has mildew-resistant and mycotoxin adsorption dual effect, has effectively controlled the feedstuff quality, up to now, also do not have similar technology at home and abroad in the publication public publication cross also unexposed the use.
Summary of the invention
The objective of the invention is to be to provide a kind of mould inhibitor with mould inhibitor and moldin adsorption dual effect, prescription is reasonable, sterilizing power is strong, easy to use, with low cost.
Another object of the present invention is the preparation method who has been to provide a kind of mould inhibitor, and is easy to implement the method, easy and simple to handle, quick.
In order to realize purpose of the present invention, the raw material that mould inhibitor of the present invention contains following weight portion is made:
Alumino-silicate 20-70
Propionic acid 10-40
Propionate 1-50
Organic acid 1-30
Mould inhibitor optimum feed stock weight portion of the present invention is:
Alumino-silicate 30-60
Propionic acid 20-35
Propionate 5-30
Organic acid 3-10
Mould inhibitor preferred feedstock weight portion of the present invention is:
Alumino-silicate 55
Propionic acid 30
Propionate 5
Organic acid 10
Alumino-silicate of the present invention is the hydrated aluminosilicate ore, and this alumino-silicate has the big and strong characteristics of ion adsorption capacity of specific surface area.But conventional alumino-silicate exists anti-mold effect single and vitamin and mineral salt are had a shortcoming of non-selective absorption, the breakthrough employing alumino-silicate of the present invention uses as the carrier of mould inhibitor, can not only effectively reduce cost, also obtain beyond thought effect simultaneously.Test shows that the mould inhibitor anti-mold effect that obtains by the present invention reaches more than 90%; Greater than 85%, zearalenone is greater than 50% to common AFB1 adsorption rate, and to various vitamin adsorption rates less than 5%.
Organic acid of the present invention is formic acid, acetate, butyric acid, one or more in the sodium Diacetate.
In order to reach purpose of the present invention, a kind of mould inhibitor with mildew-resistant and mycotoxin adsorption dual effect of the present invention is prepared from by following routine step:
A, choose hydrated aluminosilicate, pulverize, cross 80～200 mesh sieves through ball mill pulverizer.
B, be that the hydrochloric acid of 3-20% soaked the hydrated aluminosilicate mineral dust 1-3 hour down at normal temperature (20-25 ℃) with isopyknic percent concentration, the powder behind rotation agglomerate under the 300-700 ℃ of temperature then.
C, add propionate and organic acid salt in proportion, fully stir, add propionic acid by sprayer simultaneously, mix and promptly get described mould inhibitor.
The present invention compared with prior art has the following advantages and the effectiveness effect:
1, the mould inhibitor that obtains by the method for the invention can effectively solve feed mold and the mould contamination in feed production and the storage process, guarantee feed quality and animal health, reduce antibiotic use, minimizing is to the pollution of environment, for conventional feed use to add a large amount of antibiosis usually the method for mildew-resistant anti-mildew substitute products are provided, can effectively keep the animal body microecological balance, strengthen the animal immune level, for national food security provides safeguard, has great social benefit.
2, the present invention passes through compounded technology, having overcome conventional alumino-silicate exists anti-mold effect single and vitamin and mineral salt are had a shortcoming of non-selective absorption, simultaneously its carrier as mould inhibitor is used, make full use of the big and strong characteristics of ion adsorption capacity of its specific surface area, effectively raise the mildew-resistant and the adsorption capacity of this product, the aflatoxin B1 adsorption rate reaches 80%, and zearalenone is greater than 50%, and various vitamin adsorption rates are less than 5%.
3, easy to use, mould inhibitor of the present invention both can use as mold toxin sorbent separately, also can add in the mould inhibitor and use the cost performance height jointly.
4, the raw materials for production of the present invention's employing have the characteristics that are easy to get of simplifying, and have effectively controlled production cost.And production technology of the present invention is simple and efficient, and is nuisanceless to environment simultaneously, and noresidue has high performance price ratio.
Embodiment
The present invention is described in further detail below in conjunction with embodiment, but be not limitation of the present invention, all any this areas of doing according to the disclosure of invention be equal to replacement, all belong to protection scope of the present invention.
A kind of proportioning of mould inhibitor is as follows:
| Alumino-silicate | Propionic acid | Propionate | Organic acid | |
| Embodiment 1 | 65 | 35 | 1 | Formic acid 5 |
| Embodiment 2 | 60 | 30 | 5 | Acetate 20 |
| Embodiment 3 | 52 | 25 | 35 | Butyric acid 15 |
| Embodiment 4 | 45 | 20 | 45 | Sodium Diacetate 25 |
| Embodiment 5 | 40 | 15 | 30 | Formic acid 10 |
| Embodiment 6 | 25 | 40 | 50 | Butyric acid 30 |
Its step is as follows:
A, choose hydrated aluminosilicate, pulverize, cross 80～200 mesh sieves through ball mill pulverizer.
B, be that the hydrochloric acid of 3-20% soaked the hydrated aluminosilicate mineral dust 1-3 hour down at normal temperature (20-25 ℃) with isopyknic percent concentration, the powder behind rotation agglomerate under 300 or 320 or 350 or 380 or 400 or 450 or 480 or 500 or 550 or 600 or 650 or 700 ℃ of temperature then.
C, add propionate and organic acid salt in proportion, fully stir, add propionic acid by sprayer simultaneously, mix and promptly get described mould inhibitor.
Embodiment 7:
A, choose the hydrated aluminosilicate of 70 weight portions, pulverize, cross 80 mesh sieves through ball mill pulverizer.
B, be that 6% hydrochloric acid soaked the hydrated aluminosilicate mineral dusts 5 hours down at 25 ℃ with the equal-volume percent concentration, the powder behind rotation agglomerate under 350 ℃ of temperature then.
C, the propionate that adds 10 weight portions and the organic acid salt of 10 weight portions fully stir, and add the propionic acid of 10 weight portions by sprayer, mix and promptly get described mould inhibitor.
Embodiment 8:
A, choose the hydrated aluminosilicate of 55 weight portions, pulverize, cross 90 mesh sieves through ball mill pulverizer.
B, be that 8% hydrochloric acid soaked the hydrated aluminosilicate mineral dusts 2.5 hours down at 25 ℃ with the equal-volume percent concentration, the powder behind rotation agglomerate under 400 ℃ of temperature then.
C, the propionate that adds 20 weight portions and the organic acid salt of 10 weight portions fully stir, and add the propionic acid of 15 weight portions by sprayer, mix and promptly get described mould inhibitor.
Embodiment 9:
A, choose the hydrated aluminosilicate of 60 weight portions, pulverize, cross 100 mesh sieves through ball mill pulverizer.
B, be that 10% hydrochloric acid soaked the hydrated aluminosilicate mineral dusts 2 hours down at 25 ℃ with the equal-volume percent concentration, the powder behind rotation agglomerate under 450 ℃ of temperature then.
C, the propionate that adds 17 weight portions and the organic acid salt of 11 weight portions fully stir, and add the propionic acid of 12 weight portions by sprayer, mix and promptly get described mould inhibitor.
Embodiment 10:
A, choose the hydrated aluminosilicate of 65 weight portions, pulverize, cross 200 mesh sieves through ball mill pulverizer.
B, be that 20% hydrochloric acid soaked the hydrated aluminosilicate mineral dusts 1 hour down at 25 ℃ with the equal-volume percent concentration, the powder behind rotation agglomerate under 500 ℃ of temperature then.
C, the propionate that adds 17 weight portions and the organic acid salt of 7 weight portions fully stir, and add the propionic acid of 11 weight portions by sprayer, mix and promptly get described mould inhibitor.
Embodiment 11:
A, choose the hydrated aluminosilicate of 55 weight portions, pulverize, cross 80 mesh sieves through ball mill pulverizer.
B, be that 15% hydrochloric acid soaked the hydrated aluminosilicate mineral dusts 1.5 hours down at 25 ℃ with the equal-volume percent concentration, the powder behind rotation agglomerate under 700 ℃ of temperature then.
C, the propionate that adds 19 weight portions and the organic acid salt of 16 weight portions fully stir, and add the propionic acid of 10 weight portions by sprayer, mix and promptly get described mould inhibitor.
Claims (10)
1. mould inhibitor with mould inhibitor and moldin adsorption dual effect is characterized in that it is made by following raw materials in parts by weight:
Alumino-silicate 20-70
Propionic acid 10-40
Propionate 1-50
Organic acid 1-30;
Described organic acid is formic acid, acetate, butyric acid, a kind of in the sodium Diacetate.
The preparation method of described alumino-silicate is as follows:
A, choose hydrated aluminosilicate, pulverize, cross 80～200 mesh sieves through ball mill pulverizer;
B, be that the hydrochloric acid of 3-20% soaked the hydrated aluminosilicate mineral dust 1-3 hour at normal temperatures with isopyknic mass fraction, the powder behind rotation agglomerate under the 300-700 ℃ of temperature then.
2. a kind of mould inhibitor with mould inhibitor mycotoxin adsorption dual effect according to claim 1 is characterized in that it is made by following raw materials in parts by weight:
Alumino-silicate 30-60
Propionic acid 20-35
Propionate 5-30
Organic acid 3-10.
3. a kind of mould inhibitor with mould inhibitor and moldin adsorption dual effect according to claim 1 is characterized in that it is made by following raw materials in parts by weight:
Alumino-silicate 55
Propionic acid 30
Propionate 5
Organic acid 10.
4. a kind of mould inhibitor with mould inhibitor and moldin adsorption dual effect according to claim 1 is characterized in that it is made by following raw materials in parts by weight:
Alumino-silicate 65
Propionic acid 35
Propionate 1
Formic acid 5.
5. a kind of mould inhibitor with mould inhibitor and moldin adsorption dual effect according to claim 1 is characterized in that it is made by following raw materials in parts by weight:
Alumino-silicate 60
Propionic acid 30
Propionate 5
Acetate 20.
6. a kind of mould inhibitor with mould inhibitor and moldin adsorption dual effect according to claim 1 is characterized in that it is made by following raw materials in parts by weight:
Alumino-silicate 52
Propionic acid 25
Propionate 35
Butyric acid 15.
7. a kind of mould inhibitor with mould inhibitor and moldin adsorption dual effect according to claim 1 is characterized in that it is made by following raw materials in parts by weight:
Alumino-silicate 45
Propionic acid 20
Propionate 45
Sodium Diacetate 25.
8. a kind of mould inhibitor with mould inhibitor and moldin adsorption dual effect according to claim 1 is characterized in that it is made by following raw materials in parts by weight:
Alumino-silicate 40
Propionic acid 15
Propionate 30
Formic acid 10.
9. a kind of mould inhibitor with mould inhibitor and moldin adsorption dual effect according to claim 1 is characterized in that it is made by following raw materials in parts by weight:
Alumino-silicate 25
Propionic acid 40
Propionate 50
Butyric acid 30.
10. realize the described preparation method of claim 1 for one kind, the steps include: with mould inhibitor of mould inhibitor and moldin adsorption dual effect
A, choose hydrated aluminosilicate, pulverize, cross 80～200 mesh sieves through ball mill pulverizer;
B, be that the hydrochloric acid of 3-20% soaked the hydrated aluminosilicate mineral dust 1-3 hour at normal temperatures with isopyknic percent concentration, the powder behind rotation agglomerate under the 300-700 ℃ of temperature then;
C, add propionate and organic acid in proportion, stir, add propionic acid by sprayer simultaneously, mix promptly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007100532821A CN101156598B (en) | 2007-09-20 | 2007-09-20 | Mould inhibitor with mildew resistant and mold toxin adsorption dual behavior as well as preparation method |
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| CN2007100532821A CN101156598B (en) | 2007-09-20 | 2007-09-20 | Mould inhibitor with mildew resistant and mold toxin adsorption dual behavior as well as preparation method |
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| CN101156598B true CN101156598B (en) | 2011-01-12 |
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| CN101647595B (en) * | 2009-08-28 | 2011-10-05 | 南通中牧生物科技有限公司 | Alanine compound mildew preventive and preparation method thereof |
| CN102415476B (en) * | 2011-12-08 | 2013-04-03 | 成都枫澜科技有限公司 | Bacteriostatic and moldproof fish flavor liquid flavoring agent and preparation process thereof |
| CN103461677B (en) * | 2013-09-25 | 2015-04-29 | 南京日升昌生物技术有限公司 | Mold removal agent for animal feed as well as preparation method and application of mold removal agent |
| CN103988989B (en) * | 2014-04-17 | 2016-08-24 | 上海邦成生物工程有限公司 | A kind of feedstuff liquid mildew preventive with mildew-resistant, water conservation effect |
| CN105661253A (en) * | 2016-03-03 | 2016-06-15 | 吉林远通矿业有限公司 | Mildew-proof and mildew-removing agent of compound feed and preparation method of mildew-proof and mildew-removing agent |
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