CN101141986A - A bandage with enhanced hemostatic effect - Google Patents

A bandage with enhanced hemostatic effect Download PDF

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Publication number
CN101141986A
CN101141986A CNA2005800490940A CN200580049094A CN101141986A CN 101141986 A CN101141986 A CN 101141986A CN A2005800490940 A CNA2005800490940 A CN A2005800490940A CN 200580049094 A CN200580049094 A CN 200580049094A CN 101141986 A CN101141986 A CN 101141986A
Authority
CN
China
Prior art keywords
binder
pollen
powder
pollen typhae
adhesive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2005800490940A
Other languages
Chinese (zh)
Inventor
米尼·托马斯
阿吉特·曼克
艾伦·海特
武镇忆
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johnson Co Ltd
Original Assignee
Johnson Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson Co Ltd filed Critical Johnson Co Ltd
Publication of CN101141986A publication Critical patent/CN101141986A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/40Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/04Materials for stopping bleeding

Abstract

This invention relates to a bandage with enhanced hemostatic effect. It consists of anon-woven fabric impregnated with typha pollen either in the powder form or as an extract. A combination of non-woven fabric and typha pollen powder has shown improved hemostatic activity and lowers bleeding time.

Description

Binder with enhanced haemostatic effect
Technical field
The present invention relates to have the binder of enhanced haemostatic effect.Specifically, the present invention relates to the binder of similar Bandaid (Band-Aid) board adhesive bandage, described binder is made of the adhesive-bonded fabric that is impregnated with Pollen Typhae (typha pollen).
Background technology
Disclosed the purposes of the typha powder that obtains by the grinding dry flower among WO 2004 4039387A1.The manufacture method of the hemorrhage that is used to stop blooding and heals a wound is disclosed in the patent application IN 03 00279 that announced on May 13rd, 2004.This invention has disclosed the following step: select the thick stem of plant typha, with cotton matter separate with stem, autoclaving to be to remove demodicid mite class (if any), dry and purified product, to grind, make product by fine mesh sieve, then by this product being carried out radiation gamma with sterilization.U.S. Patent application 20040161524A1 has disclosed the purposes of this plant extract as Food ﹠ Drink.US 20040018261 relates to the method and the purposes of Typhaceae member's extract.This invention has proposed to be rich in the extract such as the Pollen Typhae of given activity materials such as flavonol glucosides, and can be by its capsule, pouch, granule, solution and syrup etc. of making alcoholic Pollen Typhae and containing the Pollen Typhae of vinegar.
Summary of the invention
The present invention relates to a kind of novel binder with enhanced anastalsis.Multi-form Pollen Typhae is embedded in the adhesive-bonded fabric, finds to have demonstrated hemostasia effect.When above-mentioned two kinds of combinations of substances are obviously demonstrated enhanced anastalsis when being used to cover hemorrhage wound.Discovery of the present invention is that Pollen Typhae is impregnated into the effect that can demonstrate on the adhesive-bonded fabric about bleeding stopping period with a certain concentration (under this concentration, itself there is no hemostasia effect Herba Typhae).Itself all can not shorten bleeding stopping period typha powder itself or adhesive-bonded fabric.When after Herba Typhae and adhesive-bonded fabric mutually combine, being applied to bleeding wound, can shorten bleeding stopping period.
Detailed data provides below:
Sample Bleeding stopping period (minute)
1 Undressed adhesive-bonded fabric 7.62
2 The 100mg typha pollen powder 7.266
3 The 1mg typha pollen powder Can not stop blooding/can not cover wound
4 The adhesive-bonded fabric that contains the 1mg typha pollen powder 4.62
5 The adhesive-bonded fabric that contains the 18mg typha pollen powder 3.24
6 Gauze Greater than 12 minutes
7 Calcium alginate 5.35
The needed bleeding stopping period of the typha pollen powder of undressed adhesive-bonded fabric and 100mg much at one.In addition, the combination that can determine adhesive-bonded fabric and a certain amount of Herba Typhae (itself can not stop blooding) demonstrates the shortest bleeding stopping period.
The present invention relates to have the binder of enhanced haemostatic effect.This binder comprises adhesive-bonded fabric and the combination that impregnated in Pollen Typhae wherein.Pollen Typhae can be used with form of powder, and perhaps the extract of typha powder also can be used for this dipping.
The specific embodiment
Binder of the present invention can prepare by Pollen Typhae be impregnated in the adhesive-bonded fabric.Following instantiation has been described the method for making this binder.
The solution that preparation is used for flooding: ethanol: the slurry of water preparation typha pollen powder at 1: 1.This solution of wide region comprises 0.25%~10% typha pollen powder.Preferable range comprises 0.5%~5% typha pollen powder.
In second step, above-mentioned slurry is immersed in the adhesive-bonded fabric, and make it remove superfluous solution by cylinder.
Typha pollen powder is to be 1mg~50mg on the pad at 2.5cm * 25cm in the range of deposition on the adhesive-bonded fabric.Preferred range of deposition is to be 1mg~18mg on the pad of 2.5cm * 25cm.
Final step is dry adhesive-bonded fabric through dipping.The adhesive-bonded fabric of handling carries out drying at 70 ℃~150 ℃.Resulting binder with fine-structure mesh cover with prevent pollen powder with the wound actual contact before lose.
Find the extract of typha pollen powder in addition, preferably the extract of its any solvent or non-woven exhibits identical hemostatic capability.
The present invention relates to have the binder of enhanced haemostatic effect, this binder comprises the adhesive-bonded fabric that is impregnated with Pollen Typhae.
The present invention comprises that also preparation has the method for binder of enhanced haemostatic effect, and this method comprises Pollen Typhae is immersed in step in the adhesive-bonded fabric.
It is evident that various alternative and variation as well known to those skilled in the art is all in the scope and boundary of the present invention and claims.

Claims (12)

1. binder with enhanced haemostatic effect, described binder comprises the adhesive-bonded fabric that is impregnated with Pollen Typhae.
2. binder as claimed in claim 1, wherein, described Pollen Typhae is in powder type.
3. binder as claimed in claim 1 or 2, wherein, described binder is impregnated with 0.25%~10% Pollen Typhae therein.
4. binder as claimed in claim 1 or 2, wherein, the binder pad of 2.5cm * 25cm is impregnated with the Pollen Typhae of 1mg~18mg therein.
5. the described binder of each claim as described above, wherein, described Pollen Typhae is in powder type.
6. as each described binder of claim 1~4, wherein, described Pollen Typhae is in the form of the solvent extractable matter of typha powder.
7. as each described binder of claim 1~6, wherein, described binder covers with the fine-structure mesh material.
8. method for preparing the binder with enhanced haemostatic effect, described method comprise the steps: the slurry extract dipping adhesive-bonded fabric with typha pollen powder, therefrom remove unnecessary fluid, then it are carried out drying.
9. method as claimed in claim 8, wherein, described slurry is by obtaining the slurrying in being preferably 1: 1 ethanol water of described pollen powder.
10. method as claimed in claim 8 or 9, wherein, described drying steps carries out at 70 ℃~150 ℃.
11. as each described method of claim 8~10, wherein, the surface of the fabric of described process dipping covers with fine-structure mesh.
12. one kind basically as the binder with enhanced haemostatic effect described herein.
CNA2005800490940A 2005-03-14 2005-05-12 A bandage with enhanced hemostatic effect Pending CN101141986A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN283MU2005 2005-03-14
IN283/MUM/2005 2005-03-14

Publications (1)

Publication Number Publication Date
CN101141986A true CN101141986A (en) 2008-03-12

Family

ID=36991330

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2005800490940A Pending CN101141986A (en) 2005-03-14 2005-05-12 A bandage with enhanced hemostatic effect

Country Status (2)

Country Link
CN (1) CN101141986A (en)
WO (1) WO2006097940A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103349792A (en) * 2013-06-18 2013-10-16 重庆金老虎科技开发有限公司 Novel band aid

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2461019B (en) 2008-04-25 2013-06-05 Medtrade Products Ltd Haemostatic material
CN114470309B (en) * 2022-03-04 2022-11-29 西南大学 Directional driving hemostasis microsphere with puncture function and preparation method thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3281323A (en) * 1963-01-08 1966-10-25 Torii Yakuhin Kabushiki Kaisha Process for preparation of the active pollen allergens
KR0167535B1 (en) * 1995-11-03 1999-01-15 오형직 An adhesive plaster for burn therapeutic agent
AU2003276684A1 (en) * 2002-10-29 2004-05-25 Satish Shantaram Mohile A process of manufacturing a heamostatic agent from typha elephantina for arresting bleeding and healing open cuts and wounds
CN1188406C (en) * 2003-02-25 2005-02-09 中国人民解放军第二军医大学 Cattail pollen extract and preparation process and use thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103349792A (en) * 2013-06-18 2013-10-16 重庆金老虎科技开发有限公司 Novel band aid
CN103349792B (en) * 2013-06-18 2015-08-26 重庆金老虎科技开发有限公司 Adhesive bandages

Also Published As

Publication number Publication date
WO2006097940A8 (en) 2006-11-09
WO2006097940A1 (en) 2006-09-21

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Open date: 20080312