CN101564549A - Traditional Chinese medicine dressing for antibacterium and hematischesis and production method thereof - Google Patents
Traditional Chinese medicine dressing for antibacterium and hematischesis and production method thereof Download PDFInfo
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- CN101564549A CN101564549A CNA200810104517XA CN200810104517A CN101564549A CN 101564549 A CN101564549 A CN 101564549A CN A200810104517X A CNA200810104517X A CN A200810104517XA CN 200810104517 A CN200810104517 A CN 200810104517A CN 101564549 A CN101564549 A CN 101564549A
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Abstract
The invention discloses a traditional Chinese medicine dressing for antibacterium and hematischesis and a production method thereof. A biological dressing prepared by taking cotton, gauze and non-woven fabrics as base materials, glycerin as a plasticizing agent and chitosan as a filmogen and dipping in a traditional Chinese medicine extracting solution for antibacterium and hematischesis can be widely used as a dressing for surfaces of wound caused by burning and hurting, has the characteristics of favorable biocompatibility, security, absorbing wound seepage, antibacterium, hematischesis, accelerating the concrescence of the wound, and the like and takes crudes as main materials.
Description
Technical field
The present invention relates to a kind of manufacture method that can be widely used in containing of wound surface of antibiotic, Hemostatic of traditional herb medicine pure-natural biological dressing.
Background technology
Wound dressing is divided into traditional dressing, biological dressing and synthetic dressing etc. according to its material composition.Wherein, biological dressing has characteristics such as excellent biological compatibility, safety, promotion wound healing be fast, therefore is subjected to people's favor.CN1275408 discloses from epithelium of animal and dermal tissue and to have extracted the technology that bioactive substance and collagen prepare biological dressing; CN1380109 has reported a kind of chitosan, collagen and calcium alginate compounded spongy biological dressing and processing technology thereof; " Chinese biological engineering in medicine journal " (1996,15 (2)) have reported that with chitosan, gelatin and glycerol be base stock, prepare wound dressing with glutaraldehyde as cross linker.Antibiotic, hemostatic function defect of insufficient that these biological dressings exist." institute of Military Medical Science Institute periodical " (1993,17 (1)) has reported the research of chitosan one norfloxacin burn dressing, the non-pure natural substance of this dressing, and synthetic drug wherein has certain toxic and side effects.And the chitosan that this series products is used makes the amino amount of product activity reduce owing to passed through the chemical modification processing of physics recrystallization or high substituted degree in the preparation process, and biocidal property reduces, and controls the traumatic infection ability and weakens.Therefore to have pure-natural biological dressing antibiotic, hemostatic function be significant and practical value in exploitation.
Summary of the invention
Main purpose of the present invention is to address the above problem, the dressing of a kind of antibacterial anti hemorrhagic Chinese medicine is provided, that this dressing contains is antibiotic, the pure-natural biological dressing of Hemostatic of traditional herb medicine, makes it possess excellent biological compatibility, safety, antibiotic, worker's exhaustion of blood simultaneously, promotes good characteristic such as wound healing.
In order to achieve the above object, technical scheme provided by the invention is: the dressing of a kind of antibacterial anti hemorrhagic Chinese medicine is base material with Cotton Gossypii, gauze or non-woven fabrics, dipping glycerol, chitosan solution, the Hemostatic of traditional herb medicine extracting solution is flooded in oven dry again, drying promptly gets and contains the dressing of antibacterial anti hemorrhagic Chinese traditional medicine biology.
Operation principle of the present invention and beneficial effect:
The present invention uses Cotton Gossypii, gauze or non-woven fabrics to play absorption wound exudate, the effect of protection wound surface.Glycerol plays the plasticizer effect, can make the dressing softness.Antibacterial extracting solution has good inhibition effect as the extracting solution of Rhizoma Coptidis, Cortex Phellodendri to common infectious bacteria staphylococcus aureus of skin and bacillus pyocyaneus, mainly plays bacteriostasis, and the hemostasis extracting solution plays the hemostasis effect as Radix Et Rhizoma Rhei extract.The chitosan biologically active can stop formation, the hypertrophy of connective tissue cell and the synthesizing of collagen protein of fibrin element, and have excellent biological compatibility, can absorb wound exudate, promotes characteristics such as wound healing and skin regeneration.In addition, chitosan has absorption, slow releasing function to medicine, makes the Chinese medicine effect more long-acting, avoids traumatic infection better, promotes wound healing.Uses chitosan to be filmogen, not only kept its excellent biological compatibility, and the natural Chinese medicine extracting solution is as antibiotic, hemostatic material, its safety and antibiotic, haemostatic effect is more remarkable.
The specific embodiment:
Embodiment 1:
A kind of antibacterial anti hemorrhagic Chinese medicine dressing that contains comprises Cotton Gossypii base material, 0.5% glycerol, 0.5% chitosan solution and antibacterial anti hemorrhagic Chinese medicine extraction liquid; Glycerol, chitosan and antibacterial anti hemorrhagic Chinese medicine extraction liquid are attached to base material; The manufacture method of this antibacterial anti hemorrhagic Chinese traditional medicine biology dressing, 1) with Cotton Gossypii dipping glycerol, chitosan solution, oven dry; 2) flood the Hemostatic of traditional herb medicine extracting solution again, drying promptly gets and contains the dressing of antibacterial anti hemorrhagic Chinese traditional medicine biology.
This contains the dressing of antibacterial anti hemorrhagic Chinese traditional medicine biology and uses Cotton Gossypii to play absorption wound exudate, the effect of protection wound surface.Glycerol plays the plasticizer effect, can make the dressing softness.Antibacterial extracting solution has good inhibition effect as the extracting solution of Rhizoma Coptidis, Cortex Phellodendri to common infectious bacteria staphylococcus aureus of skin and bacillus pyocyaneus, mainly plays bacteriostasis, and the hemostasis extracting solution plays the hemostasis effect as Radix Et Rhizoma Rhei extract.The chitosan biologically active can stop formation, the hypertrophy of connective tissue cell and the synthesizing of collagen protein of fibrin element, and have excellent biological compatibility, can absorb wound exudate, promotes characteristics such as wound healing and skin regeneration.In addition, chitosan has absorption, slow releasing function to medicine, makes the Chinese medicine effect more long-acting, avoids traumatic infection better, promotes wound healing.Uses chitosan to be filmogen, not only kept its excellent biological compatibility, and the natural Chinese medicine extracting solution is as antibiotic, hemostatic material, its safety and antibiotic, haemostatic effect is more remarkable.
Embodiment 2: most of identical with embodiment 1, difference is: base material is a gauze, 5% glycerol, 2.5% chitosan solution.
Embodiment 3: most of identical with embodiment 1, difference is: base material is a non-woven fabrics, 2% glycerol, 1.5% chitosan solution.
Embodiment 3: most of identical with embodiment 1, difference is: base material is non-woven fabrics and gauze, and gauze is attached to the top of non-woven fabrics, 4% glycerol, 1% chitosan solution.
In sum, the present invention contains the dressing of antibacterial anti hemorrhagic Chinese traditional medicine biology and uses Cotton Gossypii to play to absorb wound exudate, the effect of protection wound surface.Glycerol plays the plasticizer effect, can make the dressing softness.Antibacterial extracting solution has good inhibition effect as the extracting solution of Rhizoma Coptidis, Cortex Phellodendri to common infectious bacteria staphylococcus aureus of skin and bacillus pyocyaneus, mainly plays bacteriostasis, and the hemostasis extracting solution plays the hemostasis effect as Radix Et Rhizoma Rhei extract.The chitosan biologically active can stop formation, the hypertrophy of connective tissue cell and the synthesizing of collagen protein of fibrin element, and have excellent biological compatibility, can absorb wound exudate, promotes characteristics such as wound healing and skin regeneration.In addition, chitosan has absorption, slow releasing function to medicine, makes the Chinese medicine effect more long-acting, avoids traumatic infection better, promotes wound healing.Uses chitosan to be filmogen, not only kept its excellent biological compatibility, and the natural Chinese medicine extracting solution is as antibiotic, hemostatic material, its safety and antibiotic, haemostatic effect is more remarkable.
Though the present invention utilizes the foregoing description to carry out at length setting forth, and is not to limit the present invention, any those skilled in the art should do various changes and modification, without departing from the spirit and scope of the present invention, should be considered as protection scope of the present invention.
Claims (3)
1, a kind of antibacterial anti hemorrhagic Chinese medicine dressing that contains, it is characterized in that in: this contains the dressing of antibacterial anti hemorrhagic Chinese medicine and comprises base material, 0.5-5% glycerol, 0.5～2.5% chitosan solution and antibacterial anti hemorrhagic Chinese medicine extraction liquid; Described glycerol, chitosan and antibacterial anti hemorrhagic Chinese medicine extraction liquid are attached on the base material.
2, the antibacterial anti hemorrhagic Chinese medicine dressing that contains according to claim 1, it is characterized in that: described base material is one or more in Cotton Gossypii, gauze and the non-woven fabrics.
3, the manufacture method of antibacterial anti hemorrhagic Chinese traditional medicine biology as claimed in claim 1 dressing is characterized in that: be base material 1) with Cotton Gossypii, gauze or non-woven fabrics, and dipping glycerol, chitosan solution, oven dry; 2) flood the Hemostatic of traditional herb medicine extracting solution again, drying promptly gets and contains the dressing of antibacterial anti hemorrhagic Chinese traditional medicine biology.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA200810104517XA CN101564549A (en) | 2008-04-21 | 2008-04-21 | Traditional Chinese medicine dressing for antibacterium and hematischesis and production method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CNA200810104517XA CN101564549A (en) | 2008-04-21 | 2008-04-21 | Traditional Chinese medicine dressing for antibacterium and hematischesis and production method thereof |
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| CN101564549A true CN101564549A (en) | 2009-10-28 |
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| CNA200810104517XA Pending CN101564549A (en) | 2008-04-21 | 2008-04-21 | Traditional Chinese medicine dressing for antibacterium and hematischesis and production method thereof |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102134809B (en) * | 2010-01-25 | 2013-01-02 | 安徽甲特生物科技有限公司 | Antibacterial chitosan gauze and manufacturing method thereof |
| RU2508104C2 (en) * | 2011-10-20 | 2014-02-27 | Валерий Васильевич Ермилов | Antiseptic drug with haemostatic action, and method for preparing it |
| CN103623460A (en) * | 2013-12-03 | 2014-03-12 | 安徽缘远博爱生物技术有限公司 | Broad spectrum sterilization soluable hemostatic gauze |
| CN105214131A (en) * | 2015-09-26 | 2016-01-06 | 孙桂芝 | A kind of tourniquet and preparation method thereof |
| CN105214133A (en) * | 2015-09-26 | 2016-01-06 | 孙桂芝 | A kind of wound bandage accompanying medicated powder |
| CN107198790A (en) * | 2017-05-25 | 2017-09-26 | 李美英 | A kind of degradable dressing of animal doctor's antibiotic-free |
| CN109793918A (en) * | 2018-12-29 | 2019-05-24 | 中国人民解放军总医院 | It can promote the plant society dressing of extensive wound hair follicle regeneration |
| CN109847085A (en) * | 2018-12-19 | 2019-06-07 | 军事科学院系统工程研究院军用标准研究中心 | A kind of anti-infective Wound dressing and preparation method thereof that stops blooding |
| CN111228561A (en) * | 2020-01-13 | 2020-06-05 | 张新华 | Smearing-free wound dressing containing traditional Chinese medicine matrix |
| CN115928416A (en) * | 2023-02-24 | 2023-04-07 | 潍坊医学院附属医院 | Hemostatic gauze and preparation method thereof |
-
2008
- 2008-04-21 CN CNA200810104517XA patent/CN101564549A/en active Pending
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102134809B (en) * | 2010-01-25 | 2013-01-02 | 安徽甲特生物科技有限公司 | Antibacterial chitosan gauze and manufacturing method thereof |
| RU2508104C2 (en) * | 2011-10-20 | 2014-02-27 | Валерий Васильевич Ермилов | Antiseptic drug with haemostatic action, and method for preparing it |
| CN103623460A (en) * | 2013-12-03 | 2014-03-12 | 安徽缘远博爱生物技术有限公司 | Broad spectrum sterilization soluable hemostatic gauze |
| CN105214131A (en) * | 2015-09-26 | 2016-01-06 | 孙桂芝 | A kind of tourniquet and preparation method thereof |
| CN105214133A (en) * | 2015-09-26 | 2016-01-06 | 孙桂芝 | A kind of wound bandage accompanying medicated powder |
| CN107198790A (en) * | 2017-05-25 | 2017-09-26 | 李美英 | A kind of degradable dressing of animal doctor's antibiotic-free |
| CN109847085A (en) * | 2018-12-19 | 2019-06-07 | 军事科学院系统工程研究院军用标准研究中心 | A kind of anti-infective Wound dressing and preparation method thereof that stops blooding |
| CN109847085B (en) * | 2018-12-19 | 2021-12-28 | 军事科学院系统工程研究院军用标准研究中心 | Hemostatic and anti-infectious wound dressing and preparation method thereof |
| CN109793918A (en) * | 2018-12-29 | 2019-05-24 | 中国人民解放军总医院 | It can promote the plant society dressing of extensive wound hair follicle regeneration |
| CN111228561A (en) * | 2020-01-13 | 2020-06-05 | 张新华 | Smearing-free wound dressing containing traditional Chinese medicine matrix |
| CN115928416A (en) * | 2023-02-24 | 2023-04-07 | 潍坊医学院附属医院 | Hemostatic gauze and preparation method thereof |
| CN115928416B (en) * | 2023-02-24 | 2023-04-28 | 潍坊医学院附属医院 | Hemostatic gauze and preparation method thereof |
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Open date: 20091028 |