CN101129547A - 止泻口服液 - Google Patents
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Abstract
本发明涉及一种健脾益气、利水渗湿的药膳组合及其制备方法,主要由人参、茯苓、茵陈、白术、藿香、甘草等配方配比,有良好的清热散邪、涩肠止泻的作用,尤其是对治疗婴幼儿腹泻等症状效果显著;除此之外,本发明还可作为保健的常用药膳,无副作用,服用方便,有较好的经济和社会效益。
Description
技术领域
本发明涉及一种治疗婴幼儿腹泻等症状的药膳组合及制备方法,尤其是清热散邪、涩肠止泻的口服液。
背景技术
婴幼儿腹泻又名婴幼儿消化不良,是婴幼儿期的一种急性胃肠道功能紊乱,以腹泻、呕吐为主的综合征,夏秋季节发病率最高,其致病因素分为三方面:体质、感染及消化功能紊乱。
目前治疗婴幼儿腹泻诸症的药物,大多为西药,主要以抗生素为主,在患者使用过程中对机体有很大的副作用;一般的生物制剂又在治疗效果上不能满足需要,更好地为患者减轻痛苦;也有少数药效比较好的配方及成剂,但成药的服用方式药效吸收差,不能有效治疗上述疾患。
发明内容
本发明的任务是提供一种服用方便、无副作用、治疗婴幼儿腹泻效果显著的口服液。
一种用于治疗婴幼儿腹泻诸症的口服液,由多种中药成分组成,所提供的技术方案是:取人参、茯苓、茵陈各8克,白术、藿香、甘草各5克,双花4克,乌梅10克,葛根18克,陈皮、防风各6克,白糖适量,先将人参、白术、葛根、陈皮粉碎为粗末,用7倍量70%乙醇渗漉提取,滤过,浓缩并回收乙醇,取剩余药材用水煮提2次,滤过、浓缩,将白糖浓缩成糖浆,加入适量焦糖搅匀,将(上述渗漉)浓缩液与(煮提)液混合,加入防腐剂,搅匀过滤,并以蒸馏水调整至生产规定量,取上清液装入10ml已消毒、干燥的指型管所得的止泻口服液。
为实现本发明所提供的制备方法包括以下步骤:
1、粉碎:将人参、白术、葛根、陈皮粉碎为不同规格的粗末;
2、渗漉:取上述粉碎粗末用7倍量70%乙醇渗漉提取,滤过,浓缩并回收乙醇;
3、煮提:取剩余药材用水煮提2次,第一次加水10倍量,煮沸2-3小时,第二次加水3倍量,煮沸2小时,两次滤液合并,滤过,然后浓缩;
4、炼糖:取白糖置锅内,加入50-60%的清水加热至沸,滤过,静置,取上清液浓缩成糖浆,加入适量焦糖搅匀;
5、混合:将(上述渗漉)浓缩液与(煮提)液混合,加入苯甲酸、尼泊金(防腐剂),搅匀过滤,加入糖浆,搅拌均匀,并以蒸馏水调整至生产规定量;
6、罐装:取上清液装入10ml已消毒、干燥的指型管内;
人参味甘微苦,有大补元气、益阴生津、补肺益气的功效,其药理作用有:
1、加强大脑皮质的兴奋和抑制过程,使紧张造成紊乱的神经得以恢复,其对中枢神经系统有镇静作用,对很多兴奋药有对抗作用,并能减轻中枢抑制药的抑制作用。2、提高人的脑力和体力劳动能力,对抗疲劳,提高思维活动和人体劳动效率,可改善老年人的大脑功能,对智力、记忆力减退及思维迟钝有兴奋作用。3、增强机体对有害刺激的防御能力,加强机体适应性。4、能增强机体免疫功能,防止多种原因引起的细胞下降,从而改善机体免疫功能。5、可调整血压,有抗休克作用,在心机能衰竭时,强心作用显著。6、可兴奋肾上腺皮质,有明显的抗应激作用。7、人参蛋白合成促进因子,能促进多种成分的生物合成,促进骨髓细胞分裂。
茯苓性平、味甘淡,有益脾安神、利水渗湿的功效,能治疗脾虚泄泻、心悸失眠、小便不畅、水肿等症,药理作用有:
1、利尿作用;
2、镇静作用:可抑制自发活动,并能对抗机体兴奋过度。
3、心血管系统:其提取物可使心肌收缩力加强,心率增加。
4、消化系统:有保肝作用。
5、抗肿瘤作用:对肉瘤有抑制作用,可激活局部补体。
白术苦、甘、温,有补脾益气、燥湿利水、固表止汗的功效,可促进肠胃分泌,有明显而持久的利尿作用,且能促进电解质特别是纳的排出,可显著降低血糖、保护肝脏、防止肝糖元减少,能促进体重增加及肌力增强,主要用于脾胃气虚、运化失常所致的饮食减少、脘腹虚胀、倦怠乏力、呕吐腹泻等症,还可治疗痰饮和水肿、表虚自汗等。
本发明与现有技术相比,它不用吃药、打针,也不用住院治疗,服用方便,且制药成本低,比西医常用的药物疗法使患者满意率提高了30%,治愈率达到20%,有效率在90%以上,未发现有任何毒副作用,尤其是对治疗婴幼儿腹泻等症状效果显著;除此之外,本发明还可作为保健的常用药膳,具有健脾益气、利水渗湿的功效,适合四季服用,无副作用,有较好的经济和社会效益。
具体实施方案
实际制药中,可取人参、茯苓、茵陈各8克,白术、藿香、甘草各5克,双花4克,乌梅10克,葛根18克,陈皮、防风各6克,白糖适量,先将人参、白术、葛根、陈皮粉碎为粗末,用7倍量70%乙醇渗漉提取,滤过,浓缩并回收乙醇,取剩余药材用水煮提2次,滤过、浓缩,将白糖浓缩成糖浆,加入适量焦糖搅匀,将(上述渗漉)浓缩液与(煮提)液混合,加入防腐剂,搅匀过滤,并以蒸馏水调整至生产规定量,取上清液装入10ml已消毒、干燥的指型管所得的止泻口服液,若恶心呕吐导致脱水严重者可加入麦冬、玉竹各10克入药。
下面结合实施例对本发明的内容作进一步说明:
实施例一
配伍为:人参、茯苓、茵陈各8克,白术、藿香、甘草各5克,双花4克,乌梅10克,葛根18克,陈皮、防风各6克,白糖适量。
制备方法:
1、粉碎:将人参、白术、葛根、陈皮粉碎为不同规格的粗末;
2、渗漉:取上述粉碎粗末用7倍量70%乙醇渗漉提取,滤过,浓缩并回收乙醇;
3、煮提:取剩余药材用水煮提2次,第一次加水10倍量,煮沸2-3小时,第二次加水3倍量,煮沸2小时,两次滤液合并,滤过,然后浓缩;
4、炼糖:取白糖置锅内,加入50-60%的清水加热至沸,滤过,静置,取上清液浓缩成糖浆,加入适量焦糖搅匀;
5、混合:将(上述渗漉)浓缩液与(煮提)液混合,加入苯甲酸、尼泊金(防腐剂),搅匀过滤,加入糖浆,搅拌均匀,并以蒸馏水调整至生产规定量;
6、罐装:取上清液装入10ml已消毒、干燥的指型管内;
实施例二
配伍为:人参、茯苓、茵陈各8克,白术、藿香、甘草各5克,双花4克,乌梅10克,葛根18克,陈皮、防风各6克,麦冬、玉竹各10克,白糖适量,其制备方法同实施例一。
综上所述,本发明的服用量可分为治疗和保健两种,对于患者来说可每日分2次服用,每次用量10ml,作为常人保健药膳服用时间不限,本发明无任何副作用,用药安全性能高,可每日1次服用,本发明呈黄色液体,药物有效期为1-2年,配伍中的各药物及其制备方法是根据“中华人民共和国药典”选用。
本发明治疗的理论根据是以清热散邪、涩肠止泻的人参、茯苓、茵陈、白术、藿香、甘草等作为原料,通过直接口服的方式给药,经临床试验表明,本发明有良好的健脾益气、利水渗湿的作用,有效率在90%以上,为临床治疗婴幼儿腹泻等症状提供了有力的依据。
Claims (2)
1.一种止泻口服液,其特征在于人参、茯苓、茵陈各8克,白术、藿香、甘草各5克,双花4克,乌梅10克,葛根18克,陈皮、防风各6克,白糖适量,先将人参、白术、葛根、陈皮粉碎为粗末,用7倍量70%乙醇渗漉提取,滤过,浓缩并回收乙醇,取剩余药材用水煮提2次,滤过、浓缩,将白糖浓缩成糖浆,加入适量焦糖搅匀,将(上述渗漉)浓缩液与(煮提)液混合,加入防腐剂,搅匀过滤,并以蒸馏水调整至生产规定量,取上清液装入10ml已消毒、干燥的指型管所得的产品。
2.根据权利要求1所述,其特征在于配方配比组成为人参、茯苓、茵陈各8克,白术、藿香、甘草各5克,双花4克,乌梅10克,葛根18克,陈皮、防风各6克,麦冬、玉竹各10克,白糖适量。
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Publication number | Priority date | Publication date | Assignee | Title |
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CN103690654A (zh) * | 2014-01-06 | 2014-04-02 | 庄成龙 | 一种治疗小儿腹泻的药物组合物 |
CN105396067A (zh) * | 2015-12-14 | 2016-03-16 | 张翠华 | 治疗小儿消化不良的方剂及制备方法 |
CN108158990A (zh) * | 2018-03-07 | 2018-06-15 | 孙奉生 | 匹伐他汀钙口服液的生产工艺 |
CN113827558A (zh) * | 2021-09-28 | 2021-12-24 | 清远八蚨生物有限公司 | 一种中药发酵与酶解的液体口服液制备方法 |
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2007
- 2007-08-20 CN CNA2007101308984A patent/CN101129547A/zh active Pending
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103690654A (zh) * | 2014-01-06 | 2014-04-02 | 庄成龙 | 一种治疗小儿腹泻的药物组合物 |
CN105396067A (zh) * | 2015-12-14 | 2016-03-16 | 张翠华 | 治疗小儿消化不良的方剂及制备方法 |
CN108158990A (zh) * | 2018-03-07 | 2018-06-15 | 孙奉生 | 匹伐他汀钙口服液的生产工艺 |
CN113827558A (zh) * | 2021-09-28 | 2021-12-24 | 清远八蚨生物有限公司 | 一种中药发酵与酶解的液体口服液制备方法 |
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