CN101129443A - Rhodiola rosea formulated product and method of producing the same - Google Patents
Rhodiola rosea formulated product and method of producing the same Download PDFInfo
- Publication number
- CN101129443A CN101129443A CNA2007101538365A CN200710153836A CN101129443A CN 101129443 A CN101129443 A CN 101129443A CN A2007101538365 A CNA2007101538365 A CN A2007101538365A CN 200710153836 A CN200710153836 A CN 200710153836A CN 101129443 A CN101129443 A CN 101129443A
- Authority
- CN
- China
- Prior art keywords
- radix
- rhodiola rosea
- formulated product
- radix rhodiolae
- rosea formulated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a rhodiola root preparation which is prepared mainly from raw materials of rhodiola root, acanthopanax root and epimeddium. The preparation has the functions of fatigue-resisting, antisenescence, immunity adjustment and hair protection. The invention also relates to the process for preparation.
Description
Technical field
The present invention relates to a kind of rhodiola rosea formulated product, particularly a kind of Radix Rhodiolae granule, and preparation method thereof.
Background technology
Radix Rhodiolae (Rhodioladumulosa) is Crassulaceae (Crassulaceae) plant that grows in plateau or high mountain cold district, and main effective ingredient has rhodioside (Salidroside) C
14H
20O
7And butyl alcohol (Tyrosot) C
6H
10O
2Contain starch, protein, fat, tannin, flavone compound, phenolic compound and micro-volatile oil in addition, also contain trace elements iron, aluminum, zinc, silver, cobalt, cadmium, titanium, molybdenum, manganese of biologically active etc., contain a small amount of biological alkali in leaf and the stem.Storehouse page or leaf Radix Rhodiolae (Rhodiolasaccharinensis A.Bor.) in the Radix Rhodiolae is the Crassulaceae Rhodida plant, is distributed in Jilin and Heilungkiang, and especially the Changbai Mountain in Jilin is that it mainly distributes ground.Storehouse page or leaf Radix Rhodiolae is grown in mountain tundra belt and the Yue Hua forest belt of Changbaishan area 1800～2300m more.Rhodioside (salidroside) is the maximum effective ingredient of research, surplus in the of nearly 20 in kind of the Rhodida plant about 14 kinds contain rhodioside.Studies show that for many years rhodioside has remarkable result at resisting fatigue, defying age and aspects such as raising body immunity and motor capacity.
In order to give full play to the above-mentioned effect of Radix Rhodiolae as much as possible, the invention provides a kind of is primary raw material and the rhodiola rosea formulated product that is aided with other functional medical material preparations with the Radix Rhodiolae.
Summary of the invention
The objective of the invention is to: a kind of rhodiola rosea formulated product is provided, makes it have good resisting fatigue, the anti-ageing effect of waiting for a long time.
The objective of the invention is to be achieved through the following technical solutions:
A kind of rhodiola rosea formulated product is provided, it is characterized in that its raw material comprises by weight: 5～8 parts of Radix Rhodiolaes, 2～4 parts of Radix Et Caulis Acanthopanacis Senticosis, 1～2 part and 25～35 parts glucose powders of Herba Epimedii.
Described raw material preferably comprises by weight: 6.9 parts of Radix Rhodiolaes, 2.9 parts of Radix Et Caulis Acanthopanacis Senticosis, 1 part and 29.4 parts glucose powders of Herba Epimedii.
Described raw material more preferably comprises: Radix Rhodiolae 234g, Radix Et Caulis Acanthopanacis Senticosi 100g, Herba Epimedii 34g and glucose powder 1000g.
The preferred Radix Rhodiolae of described Radix Rhodiolae.
Described Radix Rhodiolae is storehouse page or leaf Radix Rhodiolae more preferably.
The present invention also provides the preparation method of described rhodiola rosea formulated product, may further comprise the steps:
1) with Radix Rhodiolae, Radix Et Caulis Acanthopanacis Senticosi and the Herba Epimedii remove impurity of described ratio, clean, dry, pulverize, decoct with water then and filter;
2) filtrate decompression that step 1) is obtained be concentrated into cocnentration factor be 40 degrees centigrade 1: 1.9 down;
3) in step 2) add the glucose powder of described ratio in the concentrated solution that obtains, mix (can mix) with the VH mixer evenly after pelletize according to a conventional method, make the Radix Rhodiolae granule.
Described the boiling of step 1) carried branch 3 times, the 1st time 3 hours, the 2nd time 2 hours, the 3rd time 1 hour, merges 3 times decocting liquid.
Step 2) can also be the filtrate decompression that step 1) obtains to be concentrated back reuse ethanol precipitation carry out purification, obtain the purification concentrated solution;
Described is the ethanol of adding 95% in concentrated solution with ethanol precipitation purification concentrated solution, reaches 85% up to the solution ethanol content, and cold preservation was left standstill 48 hours then, reclaimed ethanol again.
The described pelletize of step 3) be with after the 14 order granulator pelletizes after drying reuse 12 mesh sieves carry out granulate, wherein drying is with far infrared canal drier drying.
Radix Rhodiolae in the preparation side of the present invention, particularly Radix Rhodiolae be China research at most, also a kind of Radix Rhodiolae of system comparatively.Studies have shown that in a large number the rhodioside that the storehouse page or leaf Radix Rhodiolae in the Radix Rhodiolae is contained, several amino acids, inorganic elements, multiple volatilization wet goods composition make it all have remarkable result in all many-sides such as defying age, resisting fatigue, antioxidation, immunomodulating.
Radix Et Caulis Acanthopanacis Senticosi in the side (Acanthopanax senticosus (Rupr.etMaxim.) Harms) is an Araliaceae, also has good efficacy at aspects such as defying age, antiviral, immunomodulating.
Herba Epimedii is the aerial parts of Berberidaceae plant Herba Epimedii (Epimdium koreanum Nakai) in the side, has the hemopoietic of promotion, regulates effects such as immunity, defying age, antiviral.
The present invention is a primary raw material with the Radix Rhodiolae, is aided with above-mentioned Radix Et Caulis Acanthopanacis Senticosi and Herba Epimedii, is prepared into health preparation, by reasonable compatibility, functions such as various raw material resisting fatigue, defying age, adjusting immunity is strengthened.
After testing, contain 0.6 gram rhodioside in average per 100 grams of rhodiola rosea formulated product of the present invention.
Rhodiola rosea formulated product effect experiment of the present invention:
1. resisting fatigue
Experimental technique:
Mice is divided into blank group, low dose group and high dose group at random, 10 every group.Freely drink water, freely get food.Except that the blank group, tried thing and adopt the oral administration method to give the rhodiola rosea formulated product 1 time/day of the embodiment of the invention 1, dosage is respectively 1.67g/kgbw and 5.01g/kg.bw, and administration is 30 days altogether.The blank group gives the distilled water with volume.Check mice body constitution amount there was no significant difference between each dosage group through F.Each organizes mice under equal conditions carries out same intensity during administration swimming with a load attached to the body, measures the time that each group is swum and exhausted to power.Record data are carried out statistical analysis and comparison.
Experimental result:
The mice swimming with a load attached to the body time of 1) administration group significantly is longer than blank group (P＜0.05; P＜0.01);
2) the serum urea level significantly is lower than blank group (P＜0.05) behind high dose administration group mouse movement bleeding from anus lactic acid area under curve and the mouse movement.
Brief summary:
Rhodiola rosea formulated product of the present invention can play significant antifatigue effect in the mice swimming exercise.
2. defying age (antioxidation)
Experimental technique:
Raise 3 groups of mices of equal conditions according to the method in the experiment 1, and with the same dose administration, just time of administration is totally 60 days.Administration finishes the back and puts to death aged mouse and extracting arterial blood, measures serum malonaldehyde (MDA), superoxide dismutase (SOD) and glutathion peroxidase (GSH-Px) level.
Experimental result:
The aged mouse serum MDA level of 1) administration group significantly is lower than blank group (P＜0.05; P＜0.01);
The aged mouse SOD in serum of 2) administration group and GSH-Px level are significantly higher than blank group (the equal P of each index of low dose group＜0.05; The equal P of each index of high dose group＜0.01);
Brief summary:
Rhodiola rosea formulated product of the present invention can effectively help body opposing oxidative damage, thus slow down aging.
The specific embodiment
Embodiment 1.
1) with 234g storehouse page or leaf Radix Rhodiolae, 100g Radix Et Caulis Acanthopanacis Senticosi and the remove impurity of 34g Herba Epimedii, clean, dry, pulverize, add moisture 3 times then and decoct, the 1st time 3 hours, the 2nd time 2 hours, the 3rd time 1 hour, merge 3 parts of decocting liquids then, filter with filter;
2) the filtrate usefulness reclaim under reduced pressure jar concentrating under reduced pressure that step 1) is obtained makes its cocnentration factor reach 40 degrees centigrade and descended 1: 1.9;
3) in step 2) add the 1000g glucose powder in the concentrated solution that obtains; with VH mixer mix homogeneously; use 14 order granulator pelletizes then; with the granule made through the rapid draing of far infrared canal drier; reuse 12 mesh sieves carry out granulate, behind ultraviolet disinfection, change the indoor autometering packaging machine packing 5g/ bag of sterilization over to; after quality inspection is qualified, seal and dispatch from the factory, make Radix Rhodiolae granule of the present invention.
Embodiment 2.
1) with 264g storehouse page or leaf Radix Rhodiolae, 100g Radix Et Caulis Acanthopanacis Senticosi and the remove impurity of 49g Herba Epimedii, clean, dry, pulverize, add moisture 3 times then and decoct, the 1st time 3 hours, the 2nd time 2 hours, the 3rd time 1 hour, merge 3 parts of decocting liquids then, filter with filter;
2) the filtrate usefulness reclaim under reduced pressure jar concentrating under reduced pressure that step 1) is obtained makes its cocnentration factor reach 40 degrees centigrade and descended 1: 1.9;
3) in step 2) add 95% ethanol in the concentrated solution that obtains, ethanol content reaches 85% in concentrated solution, and cold preservation was left standstill 48 hours then, and reuse ethanol recycling can decompression recycling ethanol obtains the concentrated solution of purification thus;
4) in the concentrated solution that step 3) obtains, add the 1000g glucose powder; with VH mixer mix homogeneously; use 14 order granulator pelletizes then; with the granule made through the rapid draing of far infrared canal drier; reuse 12 mesh sieves carry out granulate, behind ultraviolet disinfection, change the indoor autometering packaging machine packing 5g/ bag of sterilization over to; after quality inspection is qualified, seal and dispatch from the factory, make Radix Rhodiolae granule of the present invention.
Claims (10)
1. a rhodiola rosea formulated product is characterized in that its raw material comprises by weight: 5～8 parts of Radix Rhodiolaes, 2～4 parts of Radix Et Caulis Acanthopanacis Senticosis, 1～2 part and 25～35 parts glucose powders of Herba Epimedii.
2. the described rhodiola rosea formulated product of claim 1 is characterized in that described raw material comprises by weight: 6.9 parts of Radix Rhodiolaes, 2.9 parts of Radix Et Caulis Acanthopanacis Senticosis, 1 part and 29.4 parts glucose powders of Herba Epimedii.
3. the described rhodiola rosea formulated product of claim 2 is characterized in that described raw material comprises: Radix Rhodiolae 234g, Radix Et Caulis Acanthopanacis Senticosi 100g, Herba Epimedii 34g and glucose powder 1000g.
4. the described arbitrary rhodiola rosea formulated product of claim 1～3, it is characterized in that: described Radix Rhodiolae is a Radix Rhodiolae.
5. the described arbitrary rhodiola rosea formulated product of claim 1～3, it is characterized in that: described Radix Rhodiolae is a storehouse page or leaf Radix Rhodiolae.
6. the preparation method of the described rhodiola rosea formulated product of claim 1 may further comprise the steps:
1) with Radix Rhodiolae, Radix Et Caulis Acanthopanacis Senticosi and the Herba Epimedii remove impurity of described ratio, clean, dry, pulverize, decoct with water then and filter;
2) filtrate decompression that step 1) is obtained be concentrated into cocnentration factor be 40 degrees centigrade 1: 1.9 down;
3) in step 2) add the glucose powder of described ratio in the concentrated solution that obtains, pelletize according to a conventional method behind the mix homogeneously makes the Radix Rhodiolae granule.
7. the preparation method of the described rhodiola rosea formulated product of claim 6, it is characterized in that: the described decoction of step 1) divides 3 times, the 1st time 3 hours, the 2nd time 2 hours, the 3rd time 1 hour, merges 3 times decocting liquid.
8. the preparation method of the described rhodiola rosea formulated product of claim 6 is characterized in that: step 2) be the filtrate decompression that step 1) obtains to be concentrated back reuse ethanol precipitation carry out purification, obtain the purification concentrated solution;
9. the preparation method of the described rhodiola rosea formulated product of claim 8 is characterized in that: described is to add 95% ethanol in concentrated solution with ethanol precipitation purification concentrated solution, reaches 85% up to the solution ethanol content, and cold preservation was left standstill 48 hours then, reclaimed ethanol again.
10. the preparation method of the described rhodiola rosea formulated product of claim 6 is characterized in that: the described pelletize of step 3) be with after the 14 order granulator pelletizes after drying reuse 12 mesh sieves carry out granulate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101538365A CN101129443A (en) | 2007-09-13 | 2007-09-13 | Rhodiola rosea formulated product and method of producing the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101538365A CN101129443A (en) | 2007-09-13 | 2007-09-13 | Rhodiola rosea formulated product and method of producing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101129443A true CN101129443A (en) | 2008-02-27 |
Family
ID=39126953
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2007101538365A Pending CN101129443A (en) | 2007-09-13 | 2007-09-13 | Rhodiola rosea formulated product and method of producing the same |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101129443A (en) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102293302A (en) * | 2011-09-07 | 2011-12-28 | 吉林康龙药业有限公司 | Jingtianwang ginseng tea and preparation method thereof |
| CN102973685A (en) * | 2012-12-25 | 2013-03-20 | 刘国林 | Anti-fatigue traditional Chinese medicine preparation and preparation method thereof |
| CN103127276A (en) * | 2011-11-29 | 2013-06-05 | 北京清美联创干细胞科技有限公司 | Anti-aging health care preparation by promoting proliferation and differentiation in stem cells |
| CN103977056A (en) * | 2014-05-14 | 2014-08-13 | 凌春生 | Compound rhodiola rosea chewing tablet and preparing method thereof |
| CN105432888A (en) * | 2015-12-09 | 2016-03-30 | 叶国生 | Functional tea drink |
| CN107684594A (en) * | 2016-08-05 | 2018-02-13 | 江苏康缘药业股份有限公司 | A kind of pharmaceutical composition of kidney tonifying and its preparation method and application |
| CN108066448A (en) * | 2016-11-18 | 2018-05-25 | 吉林省东鳌鹿业集团有限公司 | It is a kind of to have the function of to alleviate physical fatigue, the composition and preparation method thereof of strengthen immunity |
| CN110496201A (en) * | 2019-09-24 | 2019-11-26 | 新疆华春生物药业股份有限公司 | A kind of antifatigue compound preparation and preparation method thereof |
| CN111419948A (en) * | 2020-04-02 | 2020-07-17 | 江苏康缘药业股份有限公司 | Anti-fatigue composition and preparation method and application thereof |
-
2007
- 2007-09-13 CN CNA2007101538365A patent/CN101129443A/en active Pending
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102293302A (en) * | 2011-09-07 | 2011-12-28 | 吉林康龙药业有限公司 | Jingtianwang ginseng tea and preparation method thereof |
| CN103127276A (en) * | 2011-11-29 | 2013-06-05 | 北京清美联创干细胞科技有限公司 | Anti-aging health care preparation by promoting proliferation and differentiation in stem cells |
| CN102973685A (en) * | 2012-12-25 | 2013-03-20 | 刘国林 | Anti-fatigue traditional Chinese medicine preparation and preparation method thereof |
| CN103977056A (en) * | 2014-05-14 | 2014-08-13 | 凌春生 | Compound rhodiola rosea chewing tablet and preparing method thereof |
| CN105432888A (en) * | 2015-12-09 | 2016-03-30 | 叶国生 | Functional tea drink |
| CN107684594A (en) * | 2016-08-05 | 2018-02-13 | 江苏康缘药业股份有限公司 | A kind of pharmaceutical composition of kidney tonifying and its preparation method and application |
| CN107684594B (en) * | 2016-08-05 | 2020-06-30 | 江苏康缘药业股份有限公司 | Kidney-tonifying pharmaceutical composition and preparation method and application thereof |
| CN108066448A (en) * | 2016-11-18 | 2018-05-25 | 吉林省东鳌鹿业集团有限公司 | It is a kind of to have the function of to alleviate physical fatigue, the composition and preparation method thereof of strengthen immunity |
| CN110496201A (en) * | 2019-09-24 | 2019-11-26 | 新疆华春生物药业股份有限公司 | A kind of antifatigue compound preparation and preparation method thereof |
| CN111419948A (en) * | 2020-04-02 | 2020-07-17 | 江苏康缘药业股份有限公司 | Anti-fatigue composition and preparation method and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101129443A (en) | Rhodiola rosea formulated product and method of producing the same | |
| CN100340651C (en) | Salamander health care wine and its preparation method | |
| CN100563697C (en) | Rhodiola rosea hippophae rhamnoides patch and preparation method thereof | |
| KR20130039309A (en) | Garlic and yolk extract including functionality food composite for health | |
| CN108157968A (en) | A kind of compound electuary of blueberry for adjusting and improving human endocrine system and preparation method thereof | |
| CN101129193B (en) | Compound high calcium tablet of yak medulla and method of preparing the same | |
| CN101129441B (en) | Rhodiola rosea capsule and its preparing method | |
| CN107896566A (en) | A kind of storage practice of wheat seed | |
| CN107348058A (en) | A kind of formula of the compound no residue instant tea of the special radioresistance blueberry of spacefarer and preparation method thereof | |
| CN103932179B (en) | A kind of health food and two-step fermentation preparation method thereof releasing the pressure and protect liver | |
| CN101024802B (en) | Pine-juice beer and its brewing method | |
| CN105533686A (en) | Pomegranate seed powder medicinal granules | |
| CN101904414A (en) | Chicken feed and method for processing eggs with Chinese medicinal tincture | |
| KR101223746B1 (en) | Mixed Tea Using Leaf, Root Bark and Fruit of Mulberry Tree | |
| CN109010514A (en) | Composition, health care product and the preparation method of altitude sickness prevention | |
| CN108770970A (en) | A kind of hypoglycemic instant coffee of blue or green money willow and preparation method thereof | |
| KR20040044745A (en) | The pack which is composed of a grain and an extract of salicornia herbaceea and the natural mixed extract. | |
| CN105153095A (en) | Method for extracting proanthocyanidin from grape branches | |
| CN105614438A (en) | Selenium enriched fruit and vegetable extract tablet accessorily treating diabetes and preparation method thereof | |
| CN1057683C (en) | Compound selenic-garlic health medicine and its preparation method | |
| CN109497483A (en) | One kind is containing phycocyanin and pine pollen composition and its preparation and application | |
| KR102181691B1 (en) | Health supplement food and manufacturing method thereof | |
| CN102599496A (en) | Production method and application of white jade snail dry powder | |
| KR20100129938A (en) | Fermented composition by microorganism for curing disease | |
| CN1043735C (en) | Ant preparation and its prepn. method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Open date: 20080227 |