CN101082586A - Intelligent acidum folicum detector - Google Patents
Intelligent acidum folicum detector Download PDFInfo
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- CN101082586A CN101082586A CN 200710016174 CN200710016174A CN101082586A CN 101082586 A CN101082586 A CN 101082586A CN 200710016174 CN200710016174 CN 200710016174 CN 200710016174 A CN200710016174 A CN 200710016174A CN 101082586 A CN101082586 A CN 101082586A
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- photomultiplier
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Abstract
The invention discloses an intelligent folic acid detector, which comprises the following parts: photoelectric multiplication pipe, signal amplification, discriminating and conversing device, computer, specimen carrier and light-tight box, wherein the specimen carrier is placed in the light-tight box; the photoelectric multiplication pipe is placed on the light-tight box with probe facing the detecting hole of light-tight box; the photoelectric multiplication pipe, signal amplification, discriminating and conversing device connect computer through wire sequently. The invention detects photon released out of detecting hole through chemical luminous method gathered by photoelectric multiplication pipe with data processing by computer, which can inform the folic acid content of erythron directly to complement the blank of erythron folic acid detection. The invention is simple to operate to generate stable testing result, which is easy to spread with low cost.
Description
(1) technical field
The present invention relates to a kind of Medical Devices, particularly a kind of intelligent acidum folicum detector.
(2) background technology
For a long time, generally mensuration in the clinical examination to folate content in the human serum, the shortage of judging human body folic acid is whether.In recent years, prove that after deliberation folate content in the red blood cell is 10～20 times of content of folic acid in the serum, and folate content is subjected to the influence of foeign elements such as diet, disease in the serum by what, its concentration level fluctuation is bigger.And the interference that folate content is subjected to extraneous factor in the red blood cell seldom, more can reflect the concentration level of folic acid in the tissue truly.But the method and the clinical detection instrument that also do not have direct quantitative human body red blood cell acidum folicum content up till now both at home and abroad.Only measure serum folic acid content and can not satisfy clinical medical requirement, find that especially the height of red blood cell acidum folicum level has very important value to prevention population inborn defect, the work of measuring red blood cell acidum folicum content just has a kind of new meaning.
Past serum folic acid assay generally adopts radio-immunity detection method γ-calculating instrument to carry out.This technology (be called for short RIA) is a kind of microanalysis method that radioisotope labeling and antigen-antibody reaction are combined.The classical RIA that nineteen sixty sets up makes isotope-labeled antigen and unlabelled antigen to be measured and corresponding antibody effect, under the condition of antigen excess, two kinds of antigens combine with antibody competition, try to achieve the content of determined antigen then by the radioactivity of measuring antigen antibody complex and free antigen.This method determination step is loaded down with trivial details, the reaction time long, reagent stability is poor, the more important thing is because label is a radioactive isotope, big for environment pollution, people's health there is threat, but owing to relate to methodological characteristics, speciality circles can only do something against one's will in a suitable period.In recent years because the appearance of chemical luminescence detection method, this method is highly sensitive, accuracy good, stable reagent, especially do not have environmental pollution, be suitable for, but the equipment of red blood cell acidum folicum content detects in chemiluminescence side also of no use at present in the technical application of quantitative detection of folic acid.
(3) summary of the invention
The technical problem to be solved in the present invention is: provide a kind of chemoluminescence method that is applicable to detect the intelligent acidum folicum detector of folate content.
In order to solve the problems of the technologies described above, the present invention includes photomultiplier, signal amplification, examination, conversion equipment, computing machine, sample carrier and camera bellows, the sample carrier places in the camera bellows, photomultiplier places the camera bellows top, the photomultiplier probe is over against the detection hole of camera bellows, and photomultiplier, signal amplification, examination, conversion equipment are connected by lead successively with computing machine.
For the ease of control, described sample carrier is the porous reaction plate, and the sample carrier is arranged on the drive unit that can order about its motion, and the sample carrier all is connected with counter-controller with motion with drive unit, and motion is connected on computers with counter-controller.
In order to be suitable for the measurement of single sample, described sample carrier is a pore formula carrier.
In order in time to provide standardization, standardization report to patient, described computing machine is connected with printer.
In order to guarantee the photomultiplier steady operation, include high-voltage power supply protector and high-voltage power supply, photomultiplier, high-voltage power supply protector and high-voltage power supply are formed Photo Counting System.
The invention has the beneficial effects as follows: the present invention gathers by photomultiplier and detects the photon of hole release in the chemoluminescence method detection and carry out data processing by computing machine, can directly report out red blood cell acidum folicum content, fills up the blank of this detection.The present invention is simple to operate, highly sensitive, testing result stable, is easy to penetration and promotion.The present invention is with low cost, and main is not have environmental pollution (radioactive contamination).
(4) description of drawings
Fig. 1 is a process flow diagram of the present invention.
Wherein: 1, high-voltage power supply protector, 2, high-voltage power supply, 3, photomultiplier, 4, signal amplification, examination, conversion equipment, 5, computing machine, 6, the sample carrier, 7, motion and counter-controller, 8, printer, 9, drive unit, 10, camera bellows.
(5) embodiment
Intelligent acidum folicum detector as shown in Figure 1 comprises high-voltage power supply protector 1, high-voltage power supply 2, photomultiplier 3, signal amplification, examination, conversion equipment 4, computing machine 5, sample carrier 6, motion and counter-controller 7, printer 8, drive unit 9 and camera bellows 10.
Photomultiplier 3 is arranged on the top of camera bellows 10, and photomultiplier 3 probe is over against the detection hole of camera bellows 10, and photomultiplier 3, signal amplification, examination, conversion equipment 4, computing machine 5 and printer 8 are connected successively by lead.Photomultiplier 3 connects high-voltage power supply 2, and high-voltage power supply 2 connects high-voltage power supply protector 1, and photomultiplier 3, high-voltage power supply protector 1 and high-voltage power supply 2 are formed Photo Counting System.
Principle of work: drive by drive unit 9, make gaging hole to be checked on the sample carrier 6 move on to the below of the detection mouth of camera bellows 10, photomultiplier 3 is gathered this and is detected the photon that discharges in the hole, be sent to signal amplification, examination, conversion equipment 4 again, light signal converts data-signal to and sends computing machine 5 to after amplifying, screening, motion and counter-controller 7 pass to computing machine 5 with count information, and computing machine 5 obtains folate content by software data processing, and can pass to printer 8 printings.
Claims (5)
1. intelligent acidum folicum detector, it is characterized in that: comprise photomultiplier (3), signal amplification, examination, conversion equipment (4), computing machine (5), sample carrier (6) and camera bellows (10), sample carrier (6) places in the camera bellows (10), photomultiplier (3) places camera bellows (10) top, photomultiplier (3) probe is over against the detection hole of camera bellows (10), and photomultiplier (3), signal amplification, examination, conversion equipment (4) and computing machine (5) are connected successively by lead.
2. intelligent acidum folicum detector according to claim 1, it is characterized in that: described sample carrier (6) is the porous reaction plate, sample carrier (6) is arranged on the drive unit (9) that can order about its motion, sample carrier (6) all is connected with counter-controller (7) with motion with drive unit (9), and motion and counter-controller (7) are connected on the computing machine (5).
3. intelligent acidum folicum detector according to claim 1 is characterized in that: described sample carrier (6) is a pore formula carrier.
4. according to claim 1 or 2 or 3 described intelligent acidum folicum detectors, it is characterized in that:
Described computing machine (5) is connected with printer (8).
5. intelligent acidum folicum detector according to claim 4 is characterized in that: include high-voltage power supply protector (1) and high-voltage power supply (2), described photomultiplier (3), high-voltage power supply protector (1) and high-voltage power supply (2) are formed Photo Counting System.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200710016174 CN101082586A (en) | 2007-07-06 | 2007-07-06 | Intelligent acidum folicum detector |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200710016174 CN101082586A (en) | 2007-07-06 | 2007-07-06 | Intelligent acidum folicum detector |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101082586A true CN101082586A (en) | 2007-12-05 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200710016174 Pending CN101082586A (en) | 2007-07-06 | 2007-07-06 | Intelligent acidum folicum detector |
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| CN (1) | CN101082586A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101788491A (en) * | 2010-03-15 | 2010-07-28 | 山东大学 | Wireless, interconnected and embedded type quantitative folic acid detection system and detection method thereof |
| CN102297857A (en) * | 2011-08-05 | 2011-12-28 | 山东优生医疗科技有限公司 | Intelligent red blood cell folate detector and detection method |
| CN113376186A (en) * | 2021-05-12 | 2021-09-10 | 赵静 | High-precision intelligent erythrocyte folic acid detector and detection method thereof |
-
2007
- 2007-07-06 CN CN 200710016174 patent/CN101082586A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101788491A (en) * | 2010-03-15 | 2010-07-28 | 山东大学 | Wireless, interconnected and embedded type quantitative folic acid detection system and detection method thereof |
| CN102297857A (en) * | 2011-08-05 | 2011-12-28 | 山东优生医疗科技有限公司 | Intelligent red blood cell folate detector and detection method |
| CN113376186A (en) * | 2021-05-12 | 2021-09-10 | 赵静 | High-precision intelligent erythrocyte folic acid detector and detection method thereof |
| CN113376186B (en) * | 2021-05-12 | 2022-12-23 | 无锡科金生物科技有限公司 | High-precision intelligent erythrocyte folic acid detector and detection method thereof |
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