CN101081239A - Lucidum glycopeptide and method for their production - Google Patents
Lucidum glycopeptide and method for their production Download PDFInfo
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- CN101081239A CN101081239A CN 200610035757 CN200610035757A CN101081239A CN 101081239 A CN101081239 A CN 101081239A CN 200610035757 CN200610035757 CN 200610035757 CN 200610035757 A CN200610035757 A CN 200610035757A CN 101081239 A CN101081239 A CN 101081239A
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- ganoderma
- glycopeptide
- lucidum
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- glossy ganoderma
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Abstract
The present invention is one kind of glossy ganoderma glycopeptide and its preparation process. The glossy ganoderma glycopeptides consists of wall breaking glossy ganoderma spore powder 5-15 %, glossy ganoderma spore oil 10-30 %, glossy ganoderma extract 15-40 %, and plant glycopeptide polymer for the rest. The preparation process includes the following steps: cultivating glossy ganoderma sporophore, enzymolysis biologically and crushing to break wall, alcohol reflux extracting to obtain ganoderic acid, polysaccharide and peptides, adsorption with resin and freeze drying, mixing, pelletizing and packing. The glossy ganoderma glycopeptides contains over 100 kinds of beneficial components, and has absorption rate up to 98 % and fast health effect.
Description
Technical field
The present invention relates to a kind of health product and manufacture method thereof, particularly relate to a kind of lucidum glycopeptide and manufacture method thereof.
Background technology
Ganoderma is the treasure in the pools of traditional Chinese medicine, and its effect is excellent and nontoxic, can obey clothes of a specified duration more.The Pharmacopoeia of the People's Republic of China had recorded Ganoderma as legal medical material in 2000, and health ministry has been ratified Ganoderma as new resource for food, had affirmed the status that Ganoderma medicine food has both legally.Ganoderma another name " Ganoderma Lucidum ", " Ganoderma ", " Ganoderma lucidum seu Japonicum " etc. belong to Eumycota, Basidiomycetes, Aphyllophorales, Ganoderma.Have strengthening by means of tonics, consolidate the function of setting upright; it is rich in ganoderan, Ganoderma polypeptide, triterpenes, Ganodenic acid and several amino acids etc.; two-ways regulation function of human body balance on the whole; transfer the internal body vigor; regulate human body metabolism function, impel whole internal organs or organ function normalization.
At present, the weak point of many Ganoderma series products shows on the market: 1, the extracting method of effective component of glossy ganoderma is original, backward, as decocting boil, the physical method pulverize and break cellular wall extracts, caused a large amount of losses of effective ingredient, particularly easily made highly active β type glucosan be converted into SA α type glucosan.2, active constituent content deficiency, low as the content of active polypeptide class, essential amino acid, cause the product health-care effect to reduce greatly.3, the content of polysaccharide is low in the Ganoderma, and the overwhelming majority is a α type glucosan in the polysaccharide, has stronger immunocompetence and the easier β type glucosan that is absorbed by the body and lacked.4, can't effectively replenish the trace element that cancer, tumor recovering patient very easily lack, as vitamin A, D, E, C, B family, calcium, zinc, germanium, selenium etc.5, all more important compositions are difficult in human body by all effectively, directly absorb, and digestion time is long, takes effect slowly.All these drawbacks limit the Ganoderma function maximum performance and use, can not satisfy the greatest requirements of user.
Summary of the invention
In order to overcome above technical deficiency, the invention provides that a kind of absorption is exceedingly fast, more fully a kind of lucidum glycopeptide and manufacture method thereof, lucidum glycopeptide of the present invention, broken through the difficult problem that traditional Ganoderma and ganoderma lucidum product are easily oxidized, absorption is complete and be wasted, the various active ingredients of the synthetic Ganoderma of utilization hard-core technology utilization, after this lucidum glycopeptide enters human body, exempt from digestion, its active ingredient can directly be that human body institute absorbs comprehensively, absorbance reaches more than 98%, and it is rich in various compositions to the human body beneficial up to kind more than 100, acts on human body and takes effect very fast.
The object of the present invention is achieved like this:
A kind of lucidum glycopeptide and manufacture method thereof, it mainly comprises following component: Sporoderm-broken Ganoderma Lucidum Spore powder 5%-15%, Ganoderma spore oil 10%-30%, Ganoderma entity extraction thing 15%-40%, surplus is a plant glycopeptide polymer.
The proportioning of the above each component is preferably: Sporoderm-broken Ganoderma Lucidum Spore powder 10%, Ganoderma spore oil 20%, Ganoderma entity extraction thing 30%, surplus are plant glycopeptide polymer.
Described plant glycopeptide polymer mainly is meant plant glycopeptide polymer such as Lentinus Edodes, Coriolous Dersicolor (Fr.) Quel, Cordyceps and Semen sojae atricolor.
Another object of the present invention provides a kind of manufacture method of lucidum glycopeptide, and it may further comprise the steps: utilize cultivation of glossy ganoderma raw material cultivating ganoderma entity; Ganoderma sporophore, Ganoderma spore powder are carried out biological enzymolysis, pulverize and break cellular wall; With the alcohol reflux of 40%-850%,, get Ganodenic acid, polysaccharide and peptide matters in 80 ℃ of-100 ℃ of following vacuum extraction; With resin inhale continuously from, hand over attached, lyophilization; Get Ganoderma entity extraction thing, Sporoderm-broken Ganoderma Lucidum Spore powder, Ganoderma spore oil and plant glycopeptide polymer according to prescription, carry out mixing, granulation, packing, get this product.
Described cultivation of glossy ganoderma raw material mainly is meant a kind of of Xylosmae japonici, vertebra wood or chestnut.
Among the present invention, owing to depend merely on Sporoderm-broken Ganoderma Lucidum Spore powder, Ganoderma spore oil and Ganoderma entity extraction thing, can't effectively replenish the trace element that cancer, tumor recovering patient very easily lack, so in composition, added plant glycopeptide polymer such as Lentinus Edodes, Coriolous Dersicolor (Fr.) Quel, Cordyceps, Semen sojae atricolor, to quicken patient's healing and rehabilitation.
Lucidum glycopeptide of the present invention, energy human body immunity improving power and hypoxia-bearing capability are eliminated free radical, have antitumor, prevent and treat the health care of cardiovascular disease, can improve liver, bone marrow, blood synthetic DNA, RNA, proteinic ability, life-saving etc.Peptide material in its active ingredient has the intestinal of promotion digestive and absorptive functions, rapid fatigue alleviating, functions such as blood pressure regulation, blood fat fat and immunomodulating.
In addition, this lucidum glycopeptide also shows in an application medically: cooperate the treatment of doctor to the patient better, can impel multiple disease patient's rapid healing and rehabilitation, particularly for tumor patient, strengthen function and resistance in its body, it is cured early.
Compared with prior art, the invention has the beneficial effects as follows:
1, the polysaccharide extraction process adopts modern biological enzymolysis technology, has preserved the content and the activity of polysaccharide to the utmost.
2, be difficult for the characteristics extracted at active polypeptide class material in the Ganoderma, trace element, the bioactive peptide material that composite needed by human body is wanted and strengthened trace element such as calcium, zinc, ferrum, germanium, selenium and various vitamin.Active polypeptide class material is a kind of small molecule active protein, contain abundant essential amino acid, have bioavailability efficiently, it has the intestinal of promotion digestive and absorptive functions, rapid fatigue alleviating, functions such as blood pressure regulation, blood fat fat and raising immunocompetence.
3, enter human body and exempt from digestion, active ingredient is directly absorbed by human body, and absorbance reaches more than 98%, the utilization rate height.
After this lucidum glycopeptide is taken, individual's health following points are improved: 1, good appetite, appetite is good, and gastrointestinal function is than good before taking; 2, the mental status is good, is not easy fatigue, is not easy flu; 3, sleep quality improves, and blood pressure is normal; 4, trick is strong, and the joint is not easy to ache; 5, the cancer rehabilitation patient is played the auxiliary treatment effect, have than obvious effects improving the health immune function.
Lucidum glycopeptide of the present invention, its microbiological indicator meets following standard:
| Project | Index |
| Total plate count, cfu/g≤ | 1000 |
| Coliform, MPN/100g≤ | 40 |
| Mycete, cfu/g≤ | 25 |
| Yeast, cfu/g≤ | 25 |
| Staphylococcus aureus | Must not detect |
| Hemolytic streptococcus | Must not detect |
| Shigella | Must not detect |
| Salmonella | Must not detect |
The specific embodiment
Embodiment 1:
A kind of lucidum glycopeptide and manufacture method thereof, a kind of cultivation of glossy ganoderma raw material of selection Xylosmae japonici, vertebra wood or chestnut, cultivating ganoderma entity; Ganoderma sporophore, Ganoderma spore powder are carried out biological enzymolysis, pulverize and break cellular wall; Alcohol reflux with 50% in 80 ℃ of following vacuum extraction, gets Ganodenic acid, polysaccharide and peptide matters; With resin inhale continuously from, hand over attached, lyophilization; Get Sporoderm-broken Ganoderma Lucidum Spore powder 5%, Ganoderma spore oil 10%, Ganoderma entity extraction thing 15%, surplus is a plant glycopeptide polymer, plant glycopeptide polymer comprises one or more of Lentinus Edodes, Coriolous Dersicolor (Fr.) Quel, Cordyceps and Semen sojae atricolor, carries out mixing, granulation, packing, gets this product.
Embodiment 2:
Select a kind of cultivation of glossy ganoderma raw material of Xylosmae japonici, vertebra wood or chestnut, the cultivating ganoderma entity; Ganoderma sporophore, Ganoderma spore powder are carried out biological enzymolysis, pulverize and break cellular wall; Alcohol reflux with 80% in 90 ℃ of following vacuum extraction, gets Ganodenic acid, polysaccharide and peptide matters; With resin inhale continuously from, hand over attached, lyophilization; Get Sporoderm-broken Ganoderma Lucidum Spore powder 10%, Ganoderma spore oil 20%, Ganoderma entity extraction thing 30%, surplus is a plant glycopeptide polymer, plant glycopeptide polymer can be selected one or more of Lentinus Edodes, Coriolous Dersicolor (Fr.) Quel, Cordyceps and Semen sojae atricolor, carries out mixing, granulation, packing, promptly.
Embodiment 3:
Utilize cultivation of glossy ganoderma raw material cultivating ganoderma entity; Ganoderma sporophore, Ganoderma spore powder are carried out biological enzymolysis, pulverize and break cellular wall; Alcohol reflux with 85% in 100 ℃ of following vacuum extraction, gets Ganodenic acid, polysaccharide and peptide matters; With resin inhale continuously from, hand over attached, lyophilization; Get Sporoderm-broken Ganoderma Lucidum Spore powder 15%, Ganoderma spore oil 30%, Ganoderma entity extraction thing 40%, surplus is a plant glycopeptide polymer, plant glycopeptide polymer can be selected one or more of Lentinus Edodes, Coriolous Dersicolor (Fr.) Quel, Cordyceps and Semen sojae atricolor, carries out mixing, granulation, packing, promptly.
Claims (5)
1, a kind of lucidum glycopeptide is characterized in that, it mainly comprises following component: Sporoderm-broken Ganoderma Lucidum Spore powder 5%-15%, Ganoderma spore oil 10%-30%, Ganoderma entity extraction thing 15%-40%, surplus is a plant glycopeptide polymer.
2, a kind of lucidum glycopeptide according to claim 1 is characterized in that, the proportioning of described each component is: Sporoderm-broken Ganoderma Lucidum Spore powder 10%, Ganoderma spore oil 20%, Ganoderma entity extraction thing 30%, surplus are plant glycopeptide polymer.
3, a kind of lucidum glycopeptide according to claim 1 is characterized in that, described plant glycopeptide polymer mainly comprises Lentinus Edodes, Coriolous Dersicolor (Fr.) Quel, Cordyceps and bean plant glycopeptide polymer.
4, a kind of manufacture method of lucidum glycopeptide is characterized in that, described manufacture method may further comprise the steps:
A, utilize cultivation of glossy ganoderma raw material cultivating ganoderma entity;
B, Ganoderma sporophore, Ganoderma spore powder are carried out biological enzymolysis, pulverize and break cellular wall;
The alcohol reflux of c, usefulness 40%-85% in 80 ℃ of-100 ℃ of following vacuum extraction, gets Ganodenic acid, polysaccharide and peptide matters;
D, with resin inhale continuously from, hand over attached, lyophilization;
E, get Ganoderma entity extraction thing, Sporoderm-broken Ganoderma Lucidum Spore powder, Ganoderma spore oil and plant glycopeptide polymer, carry out mixing, granulation, packing according to prescription, this product.
5, the manufacture method of a kind of lucidum glycopeptide according to claim 4 is characterized in that, described cultivation of glossy ganoderma raw material is a kind of of Xylosmae japonici, vertebra wood and chestnut.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610035757 CN101081239A (en) | 2006-06-02 | 2006-06-02 | Lucidum glycopeptide and method for their production |
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| CN 200610035757 CN101081239A (en) | 2006-06-02 | 2006-06-02 | Lucidum glycopeptide and method for their production |
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| CN101081239A true CN101081239A (en) | 2007-12-05 |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102396660A (en) * | 2011-11-27 | 2012-04-04 | 宜昌益农科技开发有限公司 | Composite agaricus bisporus polysaccharide chewable tablet and production method thereof |
| CN101297704B (en) * | 2008-05-20 | 2012-07-04 | 溧阳市天目湖保健品有限公司 | Health care food for protecting liver and manufacturing method thereof |
| CN103893223A (en) * | 2014-04-15 | 2014-07-02 | 南京中科集团股份有限公司 | Low-temperature lucid ganoderma processing method |
| CN104788534A (en) * | 2015-05-08 | 2015-07-22 | 飞潮（无锡）过滤技术有限公司 | Ganoderan tripeptide filtering system process device |
| CN106858139A (en) * | 2017-02-25 | 2017-06-20 | 寻乌县华丰蛋鸡场 | A kind of ganoderma lucidum method for producing egg |
| CN110272932A (en) * | 2019-06-10 | 2019-09-24 | 开平健之源保健食品有限公司 | A kind of preparation method of lucid ganoderma spore powder polysaccharide peptide |
| CN110724177A (en) * | 2019-09-29 | 2020-01-24 | 杨凌萃健生物工程技术有限公司 | Ganoderma glycopeptide and preparation method thereof |
| CN113598356A (en) * | 2021-07-27 | 2021-11-05 | 康道生物（南通）有限公司 | Preparation process of ganoderma lucidum spore oil soft capsule |
-
2006
- 2006-06-02 CN CN 200610035757 patent/CN101081239A/en active Pending
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101297704B (en) * | 2008-05-20 | 2012-07-04 | 溧阳市天目湖保健品有限公司 | Health care food for protecting liver and manufacturing method thereof |
| CN102396660A (en) * | 2011-11-27 | 2012-04-04 | 宜昌益农科技开发有限公司 | Composite agaricus bisporus polysaccharide chewable tablet and production method thereof |
| CN102396660B (en) * | 2011-11-27 | 2013-04-24 | 宜昌益农科技开发有限公司 | Composite agaricus bisporus polysaccharide chewable tablet and production method thereof |
| CN103893223A (en) * | 2014-04-15 | 2014-07-02 | 南京中科集团股份有限公司 | Low-temperature lucid ganoderma processing method |
| CN103893223B (en) * | 2014-04-15 | 2016-11-23 | 南京中科集团股份有限公司 | A kind of method of machining at low temperature Ganoderma |
| CN104788534A (en) * | 2015-05-08 | 2015-07-22 | 飞潮（无锡）过滤技术有限公司 | Ganoderan tripeptide filtering system process device |
| CN104788534B (en) * | 2015-05-08 | 2018-06-12 | 飞潮（无锡）过滤技术有限公司 | A kind of ganoderma lucidum polysaccharide tripeptides point filter system process device |
| CN106858139A (en) * | 2017-02-25 | 2017-06-20 | 寻乌县华丰蛋鸡场 | A kind of ganoderma lucidum method for producing egg |
| CN110272932A (en) * | 2019-06-10 | 2019-09-24 | 开平健之源保健食品有限公司 | A kind of preparation method of lucid ganoderma spore powder polysaccharide peptide |
| CN110272932B (en) * | 2019-06-10 | 2022-12-09 | 开平健之源保健食品有限公司 | Preparation method of ganoderma lucidum spore powder polysaccharide peptide |
| CN110724177A (en) * | 2019-09-29 | 2020-01-24 | 杨凌萃健生物工程技术有限公司 | Ganoderma glycopeptide and preparation method thereof |
| CN113598356A (en) * | 2021-07-27 | 2021-11-05 | 康道生物（南通）有限公司 | Preparation process of ganoderma lucidum spore oil soft capsule |
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Open date: 20071205 |