CN101066999B - 一种重组抗opn单克隆抗体及其制备方法和用途 - Google Patents
一种重组抗opn单克隆抗体及其制备方法和用途 Download PDFInfo
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- CN101066999B CN101066999B CN 200710085147 CN200710085147A CN101066999B CN 101066999 B CN101066999 B CN 101066999B CN 200710085147 CN200710085147 CN 200710085147 CN 200710085147 A CN200710085147 A CN 200710085147A CN 101066999 B CN101066999 B CN 101066999B
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- monoclonal antibody
- opn
- variable region
- sequence
- expression vector
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- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
Description
细胞株编号 | 2A3 | 2B3 | 3C5 | 4D9 | 5E6 | 6F2 | 7G2 | 8H5 | 9B2 | 8E3 | 9H4 | 6D2 | 5F2 |
表达量 (微克/毫升) | 165.4 | 152.6 | 142.9 | 256.4 | 168.9 | 153.8 | 301.5 | 251.4 | 283.1 | 152.9 | 273.2 | 146.8 | 139.3 |
Claims (8)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN 200710085147 CN101066999B (zh) | 2006-03-17 | 2007-03-14 | 一种重组抗opn单克隆抗体及其制备方法和用途 |
Applications Claiming Priority (3)
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CN200610024829.0 | 2006-03-17 | ||
CN200610024829 | 2006-03-17 | ||
CN 200710085147 CN101066999B (zh) | 2006-03-17 | 2007-03-14 | 一种重组抗opn单克隆抗体及其制备方法和用途 |
Related Child Applications (1)
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CN2012102117788A Division CN102731656A (zh) | 2006-03-17 | 2007-03-14 | 一种重组抗opn单克隆抗体及其制备方法和用途 |
Publications (2)
Publication Number | Publication Date |
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CN101066999A CN101066999A (zh) | 2007-11-07 |
CN101066999B true CN101066999B (zh) | 2013-05-15 |
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CN 200710085147 Expired - Fee Related CN101066999B (zh) | 2006-03-17 | 2007-03-14 | 一种重组抗opn单克隆抗体及其制备方法和用途 |
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Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101293924A (zh) * | 2007-04-24 | 2008-10-29 | 上海国健生物技术研究院 | 骨桥蛋白的功能表位、与其特异性结合的单克隆抗体及其在制备抗肿瘤转移药物中的用途 |
WO2011021146A1 (en) * | 2009-08-20 | 2011-02-24 | Pfizer Inc. | Osteopontin antibodies |
CN104165913B (zh) * | 2014-05-19 | 2017-05-10 | 上海大学 | 检测骨桥蛋白的电化学传感器及其构建方法 |
CN108020669B (zh) * | 2016-11-02 | 2020-06-30 | 张曼 | 尿液骨桥蛋白及其多肽片段在肺腺癌中的应用 |
CN109439688A (zh) * | 2018-12-04 | 2019-03-08 | 华南农业大学 | 一种重组慢病毒载体、重组慢病毒及其应用 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1351888A (zh) * | 2001-11-10 | 2002-06-05 | 河北医科大学 | 抗骨桥蛋白抗体类药物生产方法及用途 |
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2007
- 2007-03-14 CN CN 200710085147 patent/CN101066999B/zh not_active Expired - Fee Related
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1351888A (zh) * | 2001-11-10 | 2002-06-05 | 河北医科大学 | 抗骨桥蛋白抗体类药物生产方法及用途 |
Non-Patent Citations (1)
Title |
---|
易石坚等.OPN在肝细胞癌中的表达及其临床意义.《医药产业资讯》.2006,第3卷(第6期),1-2. * |
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CN101066999A (zh) | 2007-11-07 |
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