CN101066294B - Chinese medicine prepn for invigorating kidney to reduce urination and its prepn - Google Patents
Chinese medicine prepn for invigorating kidney to reduce urination and its prepn Download PDFInfo
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Abstract
The present invention relates to one kind of Chinese medicine preparation with functions of invigorating kidney, dispelling cold and reducing urination to treat children's enuresis. The Chinese medicine preparation is prepared with cassia 70-110 weight portions, malaytea scurfpea fruit 280-350 weight portions, mantis egg-case 70-110 weight portions, and halite 280-350 weight portions. It treats children's enuresis through warming kidney and astringing and has high treating effect.
Description
Technical field
The present invention relates to treat the Chinese medicine preparation of diseases of urinary system, in particular, be a kind of be the Chinese medicine preparation and preparation method thereof of the invigorating kidney to reduce urination made of effective ingredient with pure Chinese crude drug.
Background technology
Enuresis is common clinically disease, how take place at night, among child or the part adult enuresis or night the frequent micturition phenomenon comparatively common.Particularly child's frequency is wet the bed more than three years old, medically is being defined as " enuresis ".Medical institutions' follow-up investigation shows: wetting the bed has a strong impact on growth of children; Feel oneself inferior after 95% the child grows, personality defective such as unsociable and eccentric, the ability of handling affairs, developing as one pleases also to influence reproductive function and hereditary offspring.The enuresis sickness rate is higher, and states such as America and Europe all are reported among the 5-10 year child, and sickness rate also has 1% sickness rate up to 10% among the adult.China at school pupil's average attack rate about 10.77%.The enuresis has the obvious genetic tendency, the one side person that has the enuresis is arranged among the father and mother, children's sickness rate is 4%, is the bed wetter as father and mother both sides, and children's sickness rate has 1. vassopressin medicine up to the medicine of 75%. present western medical treatments " enuresis ": 1-deaminizating-8-dextrorotation arginine vasopressin; 2. anticholinergic agents: hydroxybutyric acid chloride; 3. tricyclic antidepressant: imipramine, amitriptyline; 4. central nervous stimulant: meclofenoxate or the like.Although existing multiple Western medicine is used for the treatment of enuresis on the market, side effect can appear in great majority, as " Western medicine meclofenoxate " can make child sleep in excitement partially, influence sleep quality; Defectives such as tricyclic antidepressant exists side effect bigger, and it is slow to take effect, and cure rate is low.
The traditional Chinese medical science is divided into deficiency of kidney-QI type, deficiency of both the splenic and pulmonary QI type, ascites of liver meridian damp-heat type, type of failure of the heart and kidney integrating with functional enuresis, and bed-wetting mostly is due to the deficiency of kidney-QI.The Chinese traditional treatment enuresis now more adopts methods such as physics massage, acupuncture, external application, though the good instant effect of acupuncture needs repeatedly acupuncture, the infant sensation is painful, is difficult for accepting, and is difficult to reach the purpose of treatment.Therefore, seek a kind of determined curative effect effectively, taking convenience, the oral formulations that has no side effect just seems particularly important.
Summary of the invention
The inventor is based on understanding and the Therapeutic Principle of motherland's medical science to enuresis invention mechanism, with reference to the modern pharmacological research achievement, based on Cortex Cinnamomi, Fructus Psoraleae (processed with salt), Ootheca Mantidis, the basic prescription of halite, theory according to the traditional Chinese medical science, through for many years pharmacology, pharmacodynamics test, filter out best combination and proportioning, thereby finished the present invention.
The present invention further discloses the preparation method of invigorating kidney to reduce urination Chinese medicine preparation.
The Chinese medicine preparation of invigorating kidney to reduce urination of the present invention is characterized in that it comprises the effective ingredient of following weight proportioning system:
Cortex Cinnamomi 70-110 part Fructus Psoraleae (processed with salt) 280-350 part
Ootheca Mantidis 70-110 part halite 280-350 part.
The preferred Chinese medicine preparation of the present invention, it comprises the Chinese medicine ingredients of following portions by weight:
Cortex Cinnamomi 80-100 part Fructus Psoraleae (processed with salt) 280-320 part
Ootheca Mantidis 80-100 part halite 280-320 part.
The Chinese medicine preparation that the present invention is more preferably, it comprises the Chinese medicine ingredients of following portions by weight:
313 parts of 94 parts of Fructus Psoraleaes of Cortex Cinnamomi (processed with salt)
313 parts of 94 parts of halites of Ootheca Mantidis.
Chinese medicine preparation of the present invention, dosage form wherein are pill, tablet, capsule, powder or granule.Preferred pill or capsule or tablet.
The present invention at least also comprises one or more pharmaceutic adjuvants, comprising: diluent, flavouring agent, lubricant, binding agent, disintegrating agent or the like.For example starch, magnesium stearate, smoothers sugar, lactose, pectin, propylene glycol, polyoxyethylene sorbitan monoleate, dextrin, starch, gelatin, methylcellulose, microcrystalline Cellulose, sucrose or the like.Chinese medicine preparation of the present invention comprises also that when making pill water content is the Mel of 17-19%.
Therefore, the present invention is the Chinese medicine preparation of preferred invigorating kidney to reduce urination especially, and it is to be become to be grouped into by following parts by weight of traditional Chinese medicines: Cortex Cinnamomi 80-100 part, Fructus Psoraleae (processed with salt) 280-320 part, Ootheca Mantidis 80-100 part, halite 280-320 part, Mel 500-590 part.
It is by 94 parts of Cortex Cinnamomis for an illustrated embodiments, 313 parts of Fructus Psoraleaes (processed with salt), 94 parts of Ootheca Mantidiss, 313 parts of halites, 570 parts of compositions of Mel.
In order to obtain best middle pharmaceutically active ingredient, the present invention can also adopt another method to prepare the invigorating kidney to reduce urination Chinese medicine preparation, and its raw materials of effective components consists of: Cortex Cinnamomi 80-100 part, Fructus Psoraleae (processed with salt) 280-320 part, Ootheca Mantidis 80-100 part, Halitum 280-320 part.
Cortex Cinnamomi wherein, Fructus Psoraleae (processed with salt) effective ingredient can adopt polar solvent to be flooded, distill, extract then volatile oil.Described polar solvent comprises water, methanol, ethanol, methanol one water mixed solvent, Different concentrations of alcohol-water mixed solvent, and for example 75%-95% aqueous solution or the like still extracts the change that the solvent polarity reduction can cause the extract indication.In order more effectively to extract Cortex Cinnamomi, Fructus Psoraleae (processed with salt) effective ingredient, the present invention is preferably through water retting, and distillating extracting oil, concentrates and obtains the medicinal residues water extraction.With Ootheca Mantidis, halite, pulverize then, cross 100 mesh sieves, mix with above-mentioned volatile oil, concentrated thick paste and add the Chinese medicine preparation that pharmaceutic adjuvant is made different dosage form.
The preparation method of invigorating kidney to reduce urination Chinese medicine preparation of the present invention, it comprises:
(1) gets recipe quantity four Chinese medicine material, pulverize, cross the 80-120 mesh sieve; Make tablet, capsule, powder or granule with optional one or more pharmaceutic adjuvants of adding.For example add an amount of alcohol granulation, add magnesium stearate then, mixing, tabletting.For example capsular again preparation method is as follows:
A gets recipe quantity Ootheca Mantidis, halite, pulverizes, and crosses 100 mesh sieves, and is standby;
B gets recipe quantity Cortex Cinnamomi, Fructus Psoraleae (processed with salt), pulverizes, and 8-10 times of water gaging flooded 1.5 hours, and distillation extraction does not distillate to there being volatile oil, and volatile oil is standby; Medicinal residues extract 1-2 time with 8-10 times of water gaging, and each 1-1.5 hour, filter, merging filtrate, filtrate is concentrated into thick paste, and is standby;
C is said extracted gained thick paste and medicinal powder mix homogeneously, drying, and crushing screening adds right amount of auxiliary materials, granulates, sieve, drying, granulate, the softgel shell of packing into, promptly.
(2) preparation method of pill is as follows: get recipe quantity four Chinese medicine material, pulverize, cross the 80-120 mesh sieve; With the Mel heating, refine to water content 17-19% sweet temperature 100-110 ℃; Stick together stirring in the medicated powder adding refining Mel well, closing; It is cool to making pill below 40 ℃ that medicine is sticked together.For example get recipe quantity four Chinese medicine material, pulverize, cross 100 mesh sieves; With Mel heating, to refine to water content 19%, 105 ℃ of honey temperature add medicated powder in the good Mel of refining, stir, and close to stick together; It is cool to 38 ℃ of pills that medicine is sticked together, the heavy 6g of every ball, promptly.The side of the various Chinese crude drugs that the present invention selects for use separates as follows:
Cortex Cinnamomi YANG invigorating, the kidney warming, cold relieving, promote blood circulation.Ancient times, how well-known doctor's proved recipe controlled infantile enuresis with Cortex Cinnamomi, cure holy Zhang Zhongjing as the Han dynasty and show shenqi pill, the Yougui Wan, the kidney-Yang-Reinforcing Bolus of Ming Dynasty's Jing-Yue Complete Works, the osmanthus liver ball of Ming Dynasty's " Wanbing Huichun, Curative Measures for All Diseases " in " Medical Treasures of the Golden Chamber ", get its ventilation promoting the circulation of blood, cold expelling heresy, effects such as conducting fire back to its origin.
Fructus Psoraleae the kidney invigorating, supporing yang, antidiarrheal.Compendium of Material Medica has the effect of " control diarrhea due to kidney-dificiency, the logical gate of vitality warms up the public region, holds back spirit ", its acrid in the mouth, big temperature." mend and want pocket children's side opinion " has the Fructus Psoraleae of controlling bed-wetting." Wei Shi family Tibetan side " controls the kidney qi cold caused by deficiency, the immoderate Fructus Psoraleae ball of urinating.
Ootheca Mantidis kidney tonifying, controlling nocturnal emission with astringent drugs, reducing urination, leukorrhagia stopping.The Shennong's Herbal record " main damaging the spleen and stomach, the hernia abdominal mass, impotence, the smart son of giving birth to of benefit, woman's blood closes lumbago, logical five types of stranguria, diuresis water channel." " property of medicine opinion " " end normal urination, void and normal urination add and use it "; The enuresis or urine number after manage property " Xu Shi tire product side ".Ootheca Mantidis is controlled enuresis, is Liver and kidney gate of vitality medicine, and merit is specially puckery.
The halite priming is gone into kidney channel.Complete square based on astringent therapy, the kidney warming reducing urination.Add honey and ball, strengthen nutrition, moisten effect.Further prove conclusively through the modern pharmacology analysis: Cortex Cinnamomi contains volatile oil, and main component is a cinnamic aldehyde, and the central nervous system is had calmness, analgesia and analgesic, cooling effect, also has powerful biocidal efficacies.Pharmacological research shows that Cortex Cinnamomi has antiulcer, diarrhea, choleretic effect, has illustrated the pharmacological action basis of Cortex Cinnamomi " warming spleen and stomach for dispelling cold " treatment coldness and pain in the epigastrium.
Fructus Psoraleae: contain 20% volatile oil, also contain compositions such as flavonoid, Coumarins, monoterpene phenolic compound in addition.Wherein Corylifolinin has dilating coronary blood vessel, effects such as excited heart.Psoralen changes prostate weight in wet base, volume, the histology of rat prostatic hyperplasia model due to the testosterone propionate and the influence of serum gonadal hormone by observing, the result shows that psoralen can make the prostate volume of the inductive prostatic hyperplasia model rat of testosterone propionate dwindle, weight of prostate alleviates, histology's hyperplasia degree alleviates, and the serum testosterone and the estradiol of rat prostate model of hyperplasia do not had the significance influence.
Ootheca Mantidis contains protein, fat, calcium citrate and glycoprotein, lipoprotein.
The invigorating kidney to reduce urination Chinese medicine preparation (commodity are called the peaceful ball of nocturia) that the inventor is prepared, wherein the associating compatibility of various Chinese crude drugs is to have passed through groping for many years, constantly experiment, selected at last, after particularly the child being suffered from the clinical trial observation of nocturia, obtained better therapeutic effect.Be that peaceful clinical 109 examples of nocturia are observed summary below.
Child's nocturia is one of common disease.Still there is not at present satisfied Therapeutic Method.We use, and new Pharmaceutical group reaches the peaceful ball of nocturia (seeing embodiment 4) that core hall pharmaceutical factory produces in the Tianjin, has successively carried out 109 routine clinical observations, has obtained effect preferably, now its treatment situation is summarized as follows:
One, clinical data
1, case is selected: child's nocturia.Except that the caused enuresis of organic disease such as cystitis, nephritis, tuberculosis of urinary system, diabetes were got rid of, all the other above child's nocturia of all 5 one full year of life were all observed treatment.This group is observed child's nocturia 109 examples altogether.
2, age and sex: patient's 73 examples that 10 one full year of life are above, 36 examples that 10 one full year of life are following, maximum 26 years old age, minimal ages 5 years old, male 68 people wherein, women 41 people.
3, course of disease time and overview: generally suffer from the disease situation from little bed-wetting, surplus the elder reaches 20 year, weak point person 3,4 years, severity extent differs, majority is to wet the bed every night, the next day of having plenty of or a few days urinate once, there also have indivedual severe patient to wet the bed every night to be several inferior.Most of infant is can not wet the bed from waking up after urine is arranged night, has plenty of also that to be waken up the back brains by the head of a family dimmed, can not consciously urinate, and causes bed-wetting.Most of patient once used different Chinese and western drugses and acupuncture and moxibustion therapy, poor effect.
Two, medication preparation and medication
1, medicament sources
The peaceful ball of nocturia (new Pharmaceutical group reaches the production of core hall pharmaceutical factory in the Tianjin), every ball 7.5g (specifically seeing embodiment 4)
2, medication: above person of ten one full year of life every day three times, each ball reduced by half below ten one full year of life.
The other drug treatment of stopping using of general continuous taking medicine three courses of treatment (seven days per courses of treatment), period in a medicine, its work, living environment are constant.Period in a medicine is avoided drink cold water and cold drinks and snachs, and should avoid catching a cold and swimming.
Three, observation of curative effect evaluation criteria:
1, clinical treatment: the back bed-wetting symptom of taking medicine hour, and comparatively do not consolidate the person;
2, take a turn for the better: the back bed-wetting number of times of taking medicine reduces, sx, but do not recover normal person as yet;
3, invalid: bed-wetting situation no change or deterioration person after two weeks of taking medicine.
Four, observation of curative effect:
1, this group is observed 109 examples altogether, all is that treatment is observed in outpatient service and visit to the parents of schoolchildren or young workers, and except that the middle for some reason drug withdrawal of individual patient, other are all taken medicine on request.Through the medication treatment and effective 104 examples of observation in three weeks, cure 59 examples its near-mid term, accounts for 54.2%, 42.4% of improvement, and unconverted 5 examples account for 3.4%, clinical total effective rate 96.6% (table 1.).
2, from the observation of clinical course of treatment stage, effective percentage is the highest in the week of taking medicine, and the 2-3 week produce effects of taking medicine is cured, and treats the peak in the 3rd week (table 2.).
The peaceful clinical observation on the therapeutic effect statistical table of table 1. nocturia
Peaceful pill for curing time of table 2. nocturia and clinical effective time statistical table
Five, discuss
1, child's nocturia mostly is due to deficient syndrome and kidney channel catch cold.Cortex Cinnamomi cold expelling in the side, Fructus Psoraleae, halite improving inspiration by invigorating the kidney, the body resistance strengthening and constitution consolidating, Ootheca Mantidis end puckery reducing urination.Its Therapeutic Principle is the kidney warming astringent therapy, treating both the principal and secondary aspects of a disease.Therefore, we have better effects to the treatment child disease of wetting the bed.
2, most infants are nighttime sleeps not waking up before the treatment, infant take medicine the back nighttime sleep have behind the urine can the back from waking up, the conscious urine in back of waking up is observed the infant back body constitution of taking medicine simultaneously and is strengthened, fatigue strength obviously alleviates.
3, period in a medicine and healing initial stage should be avoided drink cold water and cold drinks and snachs, and should avoid catching a cold and swimming, otherwise influence therapeutic effect.The patient who has takes medicine and just effectively fully recovers first course of treatment, because of eating ice lolly, drinking cold water, and the recurrence of wetting the bed again in second week.
Six, side effect
Through clinical observation, the most patients in back that take medicine have no adverse reaction.After only having individual patients to take medicine the epistaxis phenomenon is arranged, promptly die away after the drug withdrawal, do not need special handling.
The peaceful ball of urine of the present invention is that pure Chinese medicinal preparation is compared with the Chinese medicine preparation of existing other treatment nocturia, has determined curative effect, and taking convenience is difficult for recurrence, and infant is easily accepted, the characteristics that have no side effect, and it is through clinical verification, and the treatment effective percentage is more than 96.6%.
The specific embodiment
In order to explain enforcement of the present invention more fully, provide the preparation embodiment of following invigorating kidney to reduce urination Chinese medicine preparation.These embodiments only are to explain rather than limit the scope of the invention.
Embodiment 1:
Get Cortex Cinnamomi 75g, Fructus Psoraleae (processed with salt) 350g, Ootheca Mantidis 70g, halite 345g pulverizes, and crosses 100 mesh sieves; Mel refining to 100 ℃, water content 19%, is got the good Mel 543g of refining, mixes with medicated powder, stirring is closed and is sticked together; It is cool in 38-40 ℃ that medicine is sticked together, pill, and the heavy 6g of every ball, promptly.
Embodiment 2:
Get Cortex Cinnamomi 70g, Fructus Psoraleae (processed with salt) 290g, Ootheca Mantidis 105g, halite 350g pulverizes, and crosses 100 mesh sieves; Mel refining to 100 ℃, water content 19%, is got the good Mel 568g of refining, mixes with medicated powder, stirring is closed and is sticked together; It is cool in 38-40 ℃ that medicine is sticked together, pill, and the heavy 6g of every ball, promptly.
Embodiment 3:
Get Cortex Cinnamomi 110g, Fructus Psoraleae (processed with salt) 300g, Ootheca Mantidis 100g, halite 295g pulverizes, and crosses 100 mesh sieves; Mel refining to 110 ℃, water content 17%, is got the good Mel 578g of refining, mixes with medicated powder, stirring is closed and is sticked together; It is cool in 38-40 ℃ that medicine is sticked together, pill, and the heavy 6g of every ball, promptly.
Embodiment 4:
Get Cortex Cinnamomi 94g, Fructus Psoraleae (processed with salt) 313g, Ootheca Mantidis 94g, halite 313g pulverizes, and crosses 100 mesh sieves; The Mel refining to 105 ℃, water content 17%, is got the good Mel 569.8g of refining, mix with medicated powder, stirring is closed and is sticked together; It is cool in 38-40 ℃ that medicine is sticked together, pill, and the heavy 6g of every ball, promptly.
Embodiment 5:
Get Cortex Cinnamomi 80g, Fructus Psoraleae (processed with salt) 295g, Ootheca Mantidis 100g, halite 335g pulverizes, and crosses 100 mesh sieves; Mel refining to 105 ℃, water content 17%, is got the good Mel 573g of refining, mixes with medicated powder, stirring is closed and is sticked together; It is cool in 38-40 ℃ that medicine is sticked together, pill, and the heavy 6g of every ball, promptly.
Embodiment 6:
Get Cortex Cinnamomi 100g, Fructus Psoraleae (processed with salt) 320g, Ootheca Mantidis 85g, halite 290g pulverizes, and crosses 100 mesh sieves; Mel refining to 105 ℃, water content 17%, is got the good Mel 588g of refining, mixes with medicated powder, stirring is closed and is sticked together; It is cool in 38-40 ℃ that medicine is sticked together, pill, and the heavy 6g of every ball, promptly.
Embodiment 7:
(1) get Ootheca Mantidis 75g, halite 285g, pulverize, cross 100 mesh sieves, standby;
(2) get recipe quantity Cortex Cinnamomi 95g, Fructus Psoraleae (processed with salt) 335g, 8 times of water gagings flooded 1.5 hours, and distillation extraction does not distillate to there being volatile oil, and volatile oil is standby; Medicinal residues extracted 1 hour with 8 times of water gagings, filter, and merging filtrate, filtrate is concentrated into thick paste, and is standby;
(3) with said extracted gained thick paste and medicinal powder mix homogeneously, drying, crushing screening adds starch 50g, granulates, sieve, drying, granulate, the softgel shell of packing into makes 260, promptly.
Embodiment 8:
(1) get Ootheca Mantidis 110g, halite 280g, pulverize, cross 100 mesh sieves, standby;
(2) get recipe quantity Cortex Cinnamomi 80g, Fructus Psoraleae (processed with salt) 345g, 8 times of water gagings flooded 1.5 hours, and distillation extraction does not distillate to there being volatile oil, and volatile oil is standby; Medicinal residues extracted 1 hour with 8 times of water gagings, filter, and merging filtrate, filtrate is concentrated into thick paste, and is standby; (3) with said extracted gained thick paste and medicinal powder mix homogeneously, drying, crushing screening adds starch 32.5g, granulates, sieve, drying, granulate, the softgel shell of packing into, promptly.
Embodiment 9:
(1) get Ootheca Mantidis 90g, halite 300g, pulverize, cross 100 mesh sieves, standby;
(2) get recipe quantity Cortex Cinnamomi 105g, Fructus Psoraleae (processed with salt) 310g, 10 times of water gagings flooded 1.5 hours, and distillation extraction does not distillate to there being volatile oil, and volatile oil is standby; Medicinal residues extract 2 times with 8 times of water gagings, and each 1 hour, filter, merging filtrate, filtrate is concentrated into thick paste, and is standby;
(3) with said extracted gained thick paste and medicinal powder mix homogeneously, drying, crushing screening adds starch 22g, granulates, sieve, drying, granulate, the softgel shell of packing into, promptly.
Embodiment 10:
(1) get Ootheca Mantidis 95g, halite 315g, pulverize, cross 100 mesh sieves, standby;
(2) get recipe quantity Cortex Cinnamomi 95g, Fructus Psoraleae (processed with salt) 315g, 8 times of water gagings flooded 1.5 hours, and distillation extraction does not distillate to there being volatile oil, and volatile oil is standby; Medicinal residues extracted 1.5 hours with 10 times of water gagings, filter, and merging filtrate, filtrate is concentrated into thick paste, and is standby;
(3) with said extracted gained thick paste and medicinal powder mix homogeneously, drying, crushing screening adds starch 12.5g, granulates, sieve, drying, the granulate softgel shell of packing into, promptly.
Embodiment 11:
Get Cortex Cinnamomi 80g, Fructus Psoraleae (processed with salt) 320g, Ootheca Mantidis 100g, halite 310g pulverizes, and crosses 80 mesh sieves; Add the about 20g of starch, sucrose 50g adds 95% alcohol granulation, and 50 ℃ of dryings are made granule.
Embodiment 12:
Get Cortex Cinnamomi 100g, Fructus Psoraleae (processed with salt) 320g, Ootheca Mantidis 110g, halite 290g pulverizes, and crosses 100 mesh sieves; Mixing, the softgel shell of packing into promptly gets capsule.
Claims (10)
1. the Chinese medicine preparation of an invigorating kidney to reduce urination is characterized in that it comprises the effective ingredient that the following weight proportioning makes:
Cortex Cinnamomi 70-110 part processed with salt Fructus Psoraleae 280-350 part
Ootheca Mantidis 70-110 part halite 280-350 part.
2. Chinese medicine preparation as claimed in claim 1 is characterized in that it comprises the Chinese medicine ingredients of following portions by weight:
Cortex Cinnamomi 80-100 part processed with salt Fructus Psoraleae 280-320 part
Ootheca Mantidis 80-100 part halite 280-320 part.
3. Chinese medicine preparation as claimed in claim 1 is characterized in that it comprises the Chinese medicine ingredients of following portions by weight:
313 parts of 94 parts of processed with salt Fructus Psoraleaes of Cortex Cinnamomi
313 parts of 94 parts of halites of Ootheca Mantidis.
4. as each described Chinese medicine preparation of claim 1-3, dosage form wherein is pill, tablet, capsule, powder or granule.
5. as each described Chinese medicine preparation of claim 1-3, wherein also comprise one or more pharmaceutic adjuvants.
6. as Chinese medicine preparation as described in the claim 5, comprise also that wherein water content is the Mel of 17-19%.
7. the Chinese medicine preparation of an invigorating kidney to reduce urination is characterized in that making raw materials of effective components and consists of:
Cortex Cinnamomi 80-100 part, processed with salt Fructus Psoraleae 280-320 part, Ootheca Mantidis 80-100 part, Halitum 280-320 part, Mel 500-590 part.
8. Chinese medicine preparation as claimed in claim 7 is characterized in that it is made up of the Chinese medicine ingredients of following portions by weight: 94 parts of Cortex Cinnamomis, 313 parts of processed with salt Fructus Psoraleaes, 94 parts of Ootheca Mantidiss, 313 parts of halites, 570 parts of Mel.
9. the Chinese medicine preparation of an invigorating kidney to reduce urination is characterized in that making raw materials of effective components and consists of: Cortex Cinnamomi 80-100 part, processed with salt Fructus Psoraleae 280-320 part, Ootheca Mantidis 80-100 part, Halitum 280-320 part; Cortex Cinnamomi wherein, processed with salt Fructus Psoraleae effective ingredient are through water retting, and distillating extracting oil, concentrates and obtains the medicinal residues water extraction.
10. method for preparing each described invigorating kidney to reduce urination Chinese medicine preparation of claim 1-3, it comprises:
(1) A. gets recipe quantity Ootheca Mantidis, halite, pulverizes, and crosses 100 mesh sieves, and is standby;
B. get recipe quantity Cortex Cinnamomi, processed with salt Fructus Psoraleae, pulverize, 8-10 times of water gaging flooded 1.5-3 hour, and distillation extraction does not distillate to there being volatile oil, and volatile oil is standby; Medicinal residues extract 1-2 time with 8-10 times of water gaging, and each 1-1.5 hour, filter, merging filtrate, filtrate is concentrated into thick paste, and is standby;
C. with said extracted gained thick paste and medicinal powder mix homogeneously, drying, crushing screening adds medicinal right amount of auxiliary materials, granulates, sieve, drying, granulate is made tablet, capsule, powder or granule; Or
(2) get recipe quantity four Chinese medicine material, pulverize, cross 100 mesh sieves; With the Mel heating, refine to water content 17-19% sweet temperature 100-110 ℃; Medicated powder is added in the good Mel of refining, stir, close and stick together; It is cool to pill below 40 ℃ that medicine is sticked together.
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| CN105194638A (en) * | 2015-11-10 | 2015-12-30 | 冷军 | Hilum therapy medicine for treating urination and defecation disorders |
| CN106943513A (en) * | 2017-04-08 | 2017-07-14 | 林荣花 | A kind of Chinese medicinal formulae for treating infantile enuresis |
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| CN1695656A (en) * | 2004-05-12 | 2005-11-16 | 陈世忠 | Compsn. of Chinese traditional medicine for enhancing sexual function, physical strength and anti fatigue |
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