CN101053616A - Medicine for treating uremia - Google Patents
Medicine for treating uremia Download PDFInfo
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- CN101053616A CN101053616A CNA2006100769635A CN200610076963A CN101053616A CN 101053616 A CN101053616 A CN 101053616A CN A2006100769635 A CNA2006100769635 A CN A2006100769635A CN 200610076963 A CN200610076963 A CN 200610076963A CN 101053616 A CN101053616 A CN 101053616A
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Abstract
The invention discloses a medicine for treating uremia, which comprises pure natural Chinese herbals in weight percentage as follows: prepared aconite root 10.5-15.38, red sage root 8.3-10, areca 15.2-18.26, alisma rhizome * 1-2 fen (swallow), fresh oyster shell 9.71-15.46, kaladana 12, rhubarb 9.72-10.48, prepared dog button *2-3 li (swallow), leech 10, astragalus root 15.8-21.715, agaric 6.3-7.2, bornel * 1-3 li(swallow), poria 15, tetrandra root 12, akebia stem 9.28-12.125, arenobufagin *1-2 hao(swallow). Medicinals with mark * are mixed, grinded and infused with water for administration. The medicinal form can be decoction and the medicinals with mark* can be powder. The invention has simple combination, convenient preparation and usage, marked effect and no pain, it can act during 5-7 days without any side or toxic effect or sequelae.
Description
Technical field:
The present invention relates to a kind of Chinese herbal medicine, the uremic medicine of particularly a kind of treatment.
Background technology:
The uremic method of existing treatment to correct disturbance of water and electrolyte balance, correct acidosis, to dialyse, is a top priority with the misery that alleviates patient mainly.But above-mentioned therapy effect is slow and undesirable, the easily dangerous mistake state of an illness, and very person's threat to life is difficult to comparatively fast make uremia to alleviate or cure.
Goal of the invention:
Purpose of the present invention just is to overcome weak point of the prior art, provides a kind of prescription easy, making, processing, easy to use, the uremic medicine of treatment evident in efficacy.
The object of the present invention is achieved like this, and it is the medicament of being made by the pure natural herbal raw material of following percentage by weight, Radix Aconiti Lateralis Preparata 10.6-15.38, Radix Salviae Miltiorrhizae 8.3-10, DABAI 15.2-18.26, Rhizoma Alismatis 10, Camphora
※The 1-2 branch, Concha Ostreae 9.71-15.46, Semen Pharbitidis 12, Radix Et Rhizoma Rhei 9.72-10.48, Semen Strychni (processed)
※2-3 li, Hirudo 10, Radix Astragali 15.8-21.715, Polyporus 6.3-7.2, Borneolum Syntheticum
※1-3 li, Poria 15, Radix Stephaniae Tetrandrae 12, Caulis Akebiae 9.28-12.125, Venenum Bufonis
※The 1-2 milli, Radix Glycyrrhizae 10.
Preparation method of the present invention is that said herbal medicine is combined after concocting in proportion, fried one-tenth decoction,
※Medicine is combined in proportion through grinding to take after mixing it with water with medicine juice and is got final product.
Purpose of the present invention can realize that also said medicament is a said medicament on any pharmaceutics by following technical measures, said medicament be decoction,
※Medicine also can be a powder.
Compared to existing technology, it is easy that the present invention has prescription, making, processing, easy to use, and evident in efficacy, to patient's no pain, financial burden is little, the obvious effect of 5-7 daybreak, advantages such as without any side effects and sequela.
Below in conjunction with embodiment in detail the present invention is described in detail, it is the medicament of being made by the pure natural herbal raw material of following percentage by weight, Radix Aconiti Lateralis Preparata 10.6-15.38, Radix Salviae Miltiorrhizae 8.3-10, DABAI 15.2-18.26, Rhizoma Alismatis 10, Camphora
※1-2 branch (swallowing), Concha Ostreae 9.71-15.46, Semen Pharbitidis 12, Radix Et Rhizoma Rhei 9.72-10.48, Semen Strychni (processed)
※2-3 li (swallowing), Hirudo 10, Radix Astragali 15.8-21.715, Polyporus 6.3-7.2, Borneolum Syntheticum
※1-3 li (swallowing), Poria 15, Radix Stephaniae Tetrandrae 12, Caulis Akebiae 9.28-12.125, Venenum Bufonis
※1-2 milli (swallowing), Radix Glycyrrhizae 10.
Preparation method of the present invention is that said herbal medicine is combined fried one-tenth decoction in proportion after strictness is concocted,
※Medicine is combined in proportion to swallow through grinding and is got final product.Said medicament is a said medicament on any pharmaceutics, said medicament be decoction,
※Medicine also can be a powder.
The present invention is based on motherland's medical science to uremia and pathogenetic understanding and Therapeutic Principle, with reference to the modern pharmacological research achievement, filter out and to improve metabolism of nitrogen matter and nutritional status from 580 kinds of treatment uremias, improve lipid metabolism and hypercoagulability, remove the kidney immune complex, eliminate the basement membrane hypertrophy, change the pure natural Chinese herbal medicine of glomerular sclerosis.According to the theory of Chinese medical science prescription, with four generations special processing method handed down from one's ancestors, make the medicine focus of going directly, inducing diuresis to remove edema, detoxicating and resolving stagnation of pathogens, having one's ideas straightened out, it is turbid to ward off dirtyization, to remove Wan Chen Cuo, toxin such as blood creatinine, blood urea nitrogen, blood uric acid is discharged from kidney, reduce capillary permeability, promote the recovery and the regeneration of tissue, make the renal failure patient avoid or gradually reduce and break away from dialysis, to reach rehabilitation.
Instructions of taking of the present invention is that said herbal medicine is combined after concocting, fried one-tenth decoction,
※Medicine is made powder and is swallowed and get final product.Can realize purpose of the present invention.
Pharmacological action of the present invention is:
Radix Salviae Miltiorrhizae: regulate immunoreation, improve hypercoagulability, promote fibrinous degraded, reduce capillary permeability, promote the recovery and the regeneration of tissue, fall early stage uremia patient's blood urea nitrogen, blood creatinine and can increase the urine amount, suppress people's kidney fibroblast proliferation and promote its apoptosis.The a large amount of Treated with Radix Salviae Miltiorrhizae of life-time service can be improved the interstitial fibrosis pathological changes, prevent or reduce cicatrization, delay uremic generation.
Rhizoma Alismatis: orally can increase the urine amount, and increase the discharge of carbamide and sodium chloride.Rhizoma Alismatis extractum can alleviate its carbamide and the delay of cholesterol in blood to the artificial nephritis of rabbit.Rhizoma Alismatis extract can slightly suppress blood cholesterol, relaxes atherosclerotic tendency.
Camphora: to mucocutaneous local irritant effect arranged, can improve local blood circulation, can promote the mucosa secretion.The therapeutic dose of Camphora reduces nervus centralis and cardiovascular function or when obstacle is arranged, occurring multiple awake acting on.
Concha Ostreae: the calcium salt of Concha Ostreae can fine and close blood capillary, reduces the permeability of blood vessel, forms soluble calcium salt with the gastric acid effect after going into stomach, can absorb the adjusting electrolyte balance.
Semen Pharbitidis: through rabbit experiment, find that Semen Pharbitidis has discharge function, at cathartic simultaneously, and can add the activity of kidney tonifying.
Radix Et Rhizoma Rhei: 1, can improve patient's metabolism of nitrogen matter and nutritional status, delay uremic development.2, reduce the level of blood urea nitrogen, blood creatinine, improve lipid metabolism, suppress the growth of mesangial cell and renal cells, concurrent propagation of now transferring the expression of c-m °/c with the inhibition mesangial cell, and the influence of renal cells hypertrophy is surpassed influence to propagation, finally alleviate glomerular sclerosis, the delaying chronic kidney hypofunction process.3, urine protein obviously descends, and serum albumin and total protein raise.
Semen Strychni (processed): Semen Strychni (processed) alkali nitrogen oxide, can obviously suppress mice by the swollen permeability that reaches the abdominal cavity blood capillary of the ear due to the Oleum Tiglii, promote the absorption of inflammation exudate, change the local organization nutriture.
Hirudo: Hirudo liquid scalable prostacyclin I
2/ thromboxane A
2Balance is improved hemorheology, and with the renal tubular necrosis that protection intramuscular injection glycerol causes, opposing kidney ischemia suppresses the kidney hypertrophy.Can activate fibrinolytic system, experimental thrombosis is had thrombolytic effect.Its anti thrombotic action is not a prevention thrombosis, but thrombus.Hirudin all has effect to various thrombosis, and is best to phlebothrombosis and DIC effect.
The Radix Astragali: to the management of Idiopathic Nephrotic Syndrome in Children effect: by the Radix Astragali studies show that to the nephrotic syndrome rat, the Radix Astragali can make the kidney of nephrotic syndrome that albuminous excretion rate is reduced, blood albumin simultaneously raises, reduce cholesterolemia and triglyceride, clinical nephrotic syndrome is had certain treatment and hypotensive effect.This product can make coronary vasodilator and renal blood vessels expansion, and makes the expansion of whole body peripheral vessel, improves cutaneous circulation, makes patient's blood pressure drops.Diuresis: oral or injection formulation of astragalus root, all proof has diuresis, and the experimenter carries out diuretic test on one's body, prove that the Radix Astragali has medium diuresis.Animal experiment proves that diuresis is longer, gives the quiet notes astragalus liquid of dog 0.25g/kg, behind medicine 30-60min urine amount be before the administration 2.27-2.30 doubly, continue to still have in 2 hours tangible diuresis.
Polyporus: diuresis is preferably arranged, and mainly is to suppress renal tubules to due to the heavily absorption of water and electrolyte, particularly sodium, potassium, chlorine, and in addition, effect still brings high blood pressure down.
Poria: animal experiment proof Poria has diuresis, can promote electrolytical discharges such as sodium, chlorine, potassium, may be to suppress the re-absorbed result of renal tubules.
Radix Stephaniae Tetrandrae: tetrandrine has antiinflammatory, antiallergic, analgesic, analgesia, blood vessel dilating and tangible hypotensive effect.Tetrandrine can also stimulate hypophysis-interrenal system and make cortex hormone function hyperfunction.The Radix Stephaniae Tetrandrae low dose can stimulate kidney that the urine amount is increased.
Caulis Akebiae: Caulis Aristolochiae Manshuriensis preparation chronic test has significant diuresis to animal.
Venenum Bufonis: bufalin and toad distiller's yeast toxin have cardiotonic.Because of containing epinephrine in the toad distiller's yeast venom and norepinephrine has boosting, antiinflammatory action is arranged, its antiinflammatory action is similar to hormone.
Radix Glycyrrhizae: enoxolone has haemolysis.Glycyrrhizin or its calcium salt can detoxify, and to the poisoning of bacteriotoxin, medicine, snake venom, tetrodotoxin, TTX and food, interior metabolism product, certain Detoxication are arranged all, and Radix Glycyrrhizae has antiinflammatory, antianaphylaxis reagentia again.
Embodiment 1:
Zhu, man 37 years old, driver, December in 2003 first visit on the 18th.
In December, 2002 beginning sense lumbago, JIUYUE in 2003 was examined into " chronic renal failure, uremia's phase ", through using western medicine in mineral bureau hospital general, table mountain because of face, lower limbs edema, weak on the 8th, renal function is not seen improvement, dialysis is once looked into blood urea nitrogen 65.2mmol/L, flesh liver 876.15umo/L weekly, CO2 combining power, CO2 CP 11.9mmol/L, blood pressure 21/13Kpa, heart rate 100 times/minute, B ultrasonic shows renal atrophy.Shallow complexion is simple and unadorned, and lip is pale, diarrhoea every day five, six times, and dysuria, nausea and vomiting, fatigue and weakness, sexual impotence, the lower limb squamous and dry skin, light red tongue is fat simple and unadorned, and tongue is greasy in vain, the deep-thready pulse stringy and rapid pulse.Card belongs to deficiency of spleen-YANG and kidneyYANG, disturbance in functioning of QI, adverse flow of turbid QI, stomach-QI being unable to descend normally.Intend warming the kidney and strengthening the spleen, blood circulation promoting and blood stasis dispelling, the method for inducing diuresis to remove edema the turbid descending.Though accept Drug therapy of the present invention, lumbago, edema obviously alleviate after the week, blood pressure drops 18/11Kpa, and sexual impotence takes a turn for the better (penis can erect), and the lower limb squamous and dry skin disappears.On January 7th, 2004, heart rate was 78-85 time/minute, complexion is more preceding ruddy slightly, weakly slightly take a favorable turn, arranged yellow shaping soft stool on January 9, once a day, heart rate 80 times/minute, blood urea nitrogen 23.5mmol/L, flesh liver 395umol/L, CO2 combining power, CO2 CP 18.2mmo/L, change biweekly to February 19 dialysis, change every month once after 8 weeks.Stop dialysis after four months, continue to strengthen treatment with medicine of the present invention.
Embodiment 2:
Liu, man, 36 years old, first visit in June, 2004.
Be diagnosed as chronic renal failure, uremia's phase in June, 2003, does hemodialysis in First People's Hospital, Pingdingshan City, and weekly twice, carried out 4 months continuously.Blood creatinine 692.5umol/L before the dialysis, blood urea nitrogen 38.3mmol/L, hemoglobin 58g/L.Existing disease is seen: ochriasis is dark turbid, spiritlessness and weakness, and nausea and vomiting, skin itching, edema of lower limbs, oliguria, stool every day 7,8 times, pale tongue, thick fur is greasy, stringy and rolling pulse number and strong.Card belongs to heresy and accumulates to become poison, involves blood system, the resistance of the channels stasis of blood, and three warmers are not smooth, will become obstruction and rejection.Control suitable blood circulation promoting and blood stasis dispelling, inducing diuresis to remove edema, the detoxifcation the turbid descending is though use Drug therapy of the present invention.Vomiting and nausea promptly ends after 7 days, and it is cumulative to urinate, and edema is seen and disappeared, stool reduces to three, four times/day, the conscious spirit of patient takes a turn for the better, and strength has and increases, and looks into blood creatinine and blood urea nitrogen and also descends to some extent, after treating January, be decremented to for 2 times once in a week by dialysing weekly originally, stopped dialysis, used treatment by Chinese herbs fully up in February, 2005, look into blood creatinine 203.3umol/L, blood urea nitrogen 10.2mmol/L, hemoglobin 110g/L has rosy cheeks, spirit is refreshing suitable, diet is normal, and two is just as usual, in vigorous health, unconsciously tired, stable disease.
Claims (6)
1, the invention discloses the uremic medicine of a kind of treatment, it is the medicament of being made by the pure natural herbal raw material of following percentage by weight, Radix Aconiti Lateralis Preparata 10.6-15.38, Radix Salviae Miltiorrhizae 8.3-10, DABAI 15.2-18.26, Rhizoma Alismatis 10, Camphora
※1-2 branch (swallowing), Concha Ostreae 9.71-15.46, Semen Pharbitidis 12, Radix Et Rhizoma Rhei 9.72-10.48, Semen Strychni (processed)
※2-3 li (swallowing), Hirudo 10, Radix Astragali 15.8-21.715, Polyporus 6.3-7.2, Borneolum Syntheticum
※1-3 li (swallowing), Poria 15, Radix Stephaniae Tetrandrae 12, Caulis Akebiae 9.28-12.125, Venenum Bufonis
※1-2 milli (swallowing), Radix Glycyrrhizae 10.
2, according to the described a kind of preparation method for the treatment of uremic medicine of claim 1, it is characterized in that: said herbal medicine is combined in proportion, got final product through concocting the fried one-tenth decoction oral in back.
3, according to the described a kind of preparation method for the treatment of uremic medicine of claim 1, it is characterized in that: will
※Medicine is combined in proportion through grinding to powder is for oral administration and is got final product.
4, according to the uremic medicine of the described a kind of treatment of claim 1, it is characterized in that: said medicament is a said medicament on any pharmaceutics.
5, according to claim 1 or the uremic medicine of 2 described a kind of treatments, it is characterized in that: said medicament is a decoction.
6, the uremic medicine of 1 described a kind of treatment as requested is characterized in that: said
※Medicine also can be a powder.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2006100769635A CN101053616A (en) | 2006-04-13 | 2006-04-13 | Medicine for treating uremia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2006100769635A CN101053616A (en) | 2006-04-13 | 2006-04-13 | Medicine for treating uremia |
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| Publication Number | Publication Date |
|---|---|
| CN101053616A true CN101053616A (en) | 2007-10-17 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2006100769635A Pending CN101053616A (en) | 2006-04-13 | 2006-04-13 | Medicine for treating uremia |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102106980A (en) * | 2011-02-25 | 2011-06-29 | 郭迁秋 | Medicament for treating uremia and preparation method thereof |
-
2006
- 2006-04-13 CN CNA2006100769635A patent/CN101053616A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102106980A (en) * | 2011-02-25 | 2011-06-29 | 郭迁秋 | Medicament for treating uremia and preparation method thereof |
| CN102106980B (en) * | 2011-02-25 | 2013-04-17 | 郭迁秋 | Medicament for treating uremia and preparation method thereof |
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