CN102106980B - Medicament for treating uremia and preparation method thereof - Google Patents
Medicament for treating uremia and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a medicament for treating uremia and a preparation method thereof, which aim to provide a medicament which is used for treating uremia and has the advantages of low cost, good curative effect, quick rehabilitation and thorough treatment. The medicament disclosed by the invention is prepared from saururus chinensis, filiform cassytha herb, radix cocculi, akebia stem, plantain herb, stachytarpheta jamaicensis, maise, pyrrosia lingua, toadstone, common leafflower herb, clover fern, apocynirie, buntal fibre, longhairy antenoron herb, herb of smallflower beggarticks, lygodium salicifolium, clerodendranthus spicatus, common lophatherum herb and triquetrous tadehagi herb as raw materials. Practice proves that the medicament disclosed by the invention has no toxic and side effects in the process of treating uremia, and after being cured, the uremia can not relapse; all components are prepared from pure Chinese herbal medicines, the medicament has low cost, good curative effect, quick rehabilitation and short treatment cycle; and the effect of treating uremia can be achieved just by taking the medicament orally, so that the medicament is greatly convenient for patients and reduces the psychological burden of patients.
Description
Technical field
The present invention relates to a kind ofly treat uremic medicine, and the preparation method of this kind medicine.
Background technology
Uremia is the general name of the series of symptoms that occurs late period of renal failure.Chronic kidney symptom major embodiment is that the poisoning that causes of harmful substance accumulation and kidney hormone reduce the anemia that occurs and close osteopathia.Early stage modal be feel sick, the symptoms of digestive tract such as vomiting, loss of appetite.Enter late stage uremia after the stage, the whole body system all can get involved, and the serious symptoms such as heart failure, psychological problem, stupor occur, even threat to life.As seen, uremia is a kind of very fearful disease.Think that in the past uremia is incurable disease, after beginning this century, carried out dialysis process and kidney transfer operation, so that the patient's of uremia life-span is able to obvious prolongation.But the expense of doing dialysis or kidney transfer operation is quite expensive, can't afford for those low-income groups at all.And, patient is done dialysis or kidney transfer operation, greatly increased patient's misery.Two million peoples nearly the morbidity that uremia is crossed at me at present is conservative, annual neopathy number is with about 20% speed increase, uremia's major part is caused by the renal failure that chronic glomerulonephritis causes, the patient of chronic renal had can develop into uremia 30% late period nearly.How most patient can be accepted economically, can lower again in the situation of the suffered misery of patient and cure uremia, become the industry problem demanding prompt solution.
Summary of the invention
Technical problem to be solved by this invention is to overcome the deficiencies in the prior art, provide that a kind of cost is low, good effect, rehabilitation rapidly, the uremic medicine for the treatment of of thorough treatment and preparation method thereof.
The technical solution adopted in the present invention is: the present invention is used for the treatment of that uremic medicine made by the crude drug of following weight portion:
Rhizoma Saururi (Herba Saururi) 5～19 dodder laurels 8～15 Radix Cocculi Orbiculati 5～12
Caulis Akebiae 5～15 Herba Plantaginiss 8～19 Herba Stachytarphetae Jamaicensiss 9～21
Semen Maydis 15～25 Folium Pyrrosiaes 9～15 stone Bufo siccuss 5～9
Cacumen Securinegae Suffruticosae 9～15 Herba Marsileae Quadrifoliaes 9～15 Boehmeria 9～15
Herba Melicae Scabrosae 15～25 Herba Lysimachiaes 9～15 JINSUOSHI 9～15
Herba lygodii 12～25 Herba clerodendranthi spicati 15～25 Herba Lophatheris 9～15
Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 15～25.
The preparation method that the present invention is used for the treatment of uremic medicine comprises the steps:
(1) Rhizoma Saururi (Herba Saururi), dodder laurel, Radix Cocculi Orbiculati, Caulis Akebiae, Herba Plantaginis, Herba Stachytarphetae Jamaicensis, Semen Maydis, Folium Pyrrosiae, Herba Marsileae Quadrifoliae, Herba Melicae Scabrosae, Herba Lysimachiae, Herba clerodendranthi spicati, Herba Lophatheri, the Herba Desmodii Triquetri (Herba Tadehagi Triquetri) with described weight proportion is positioned in the iron pan, fry to faint yellow with low temperature, be ground into again fine powder, the rear mixing that sieves, for subsequent use;
(2) with the stone Bufo siccus of described weight proportion, JINSUOSHI, Herba lygodii, Cacumen Securinegae Suffruticosae, Boehmeria Steam by water bath 5～9 minutes respectively, it is air-dry then to be put in shady and cool place, is positioned in the iron pan again, and fry to faint yellow with low temperature, and be ground into fine powder, the rear mixing that sieves, for subsequent use;
(3) get above-mentioned steps (1) gained fine powder, above-mentioned steps (2) gained fine powder mixing, in incapsulating, make capsule.
Medicine in the such scheme belongs to Chinese medicine formula handed down from one's ancestors, is to have put into practice through long-term clinical research, can reach the effect of quick recovery to uremic treatment.Material medicine of the present invention selects medicine to be particular about, and is with strong points, utilizes white mice to carry out toxicity and pharmacological testing, the result confirms, the medicine that is mentioned in the such scheme does not all have large toxicity, can not produce any adverse influence to human body, and each material medicine all meets the pharmaceutical control law regulation.
The part material medicine is fried to faint yellow with iron pan low temperature, and another part material medicine is through Steam by water bath, air-dry fry to faint yellow with iron pan low temperature afterwards, and in then being ground into fine-powdered and incapsulating, patient can be directly oral.During treating, patient's food prohibited: the seafoods such as fish, shrimp Eriocheir sinensis, shell, Cipangopaludina chinensis, bamboo sprout, Oryza glutinosa, the meats such as beef, Carnis caprae seu ovis, Carnis Canitis, duck meat, Carnis Anseris domestica.General treatment 3～5 months just can recover rapidly the health of kidney, and also patient's psychosoma is thoroughly walked out uremic puzzlement, restorative physique.The patient need not large benefit during treating, behind physical rehabilitation, can suitably nourish.
The invention has the beneficial effects as follows: owing to the present invention is made by Rhizoma Saururi (Herba Saururi), dodder laurel, Radix Cocculi Orbiculati, Caulis Akebiae, Herba Plantaginis, Herba Stachytarphetae Jamaicensis, Semen Maydis, Folium Pyrrosiae, stone Bufo siccus, Cacumen Securinegae Suffruticosae, Herba Marsileae Quadrifoliae, Boehmeria, Herba Melicae Scabrosae, Herba Lysimachiae, JINSUOSHI, Herba lygodii, Herba clerodendranthi spicati, Herba Lophatheri, Herba Desmodii Triquetri (Herba Tadehagi Triquetri), wherein
Rhizoma Saururi (Herba Saururi): the function with clearing away damp-heat, diuresis;
Dodder laurel: the function with dispelling dampness and promoting diuresis detumescence dissipating blood stasis;
Radix Cocculi Orbiculati: have that capable water conservancy is wet, the function of reducing swelling and alleviating pain;
Caulis Akebiae: the function with clearing away heat and promoting diuresis, dredge the meridian passage;
Herba Plantaginis: the function with clearing heat and removing internal wetness, relieving stranguria by diuresis;
Herba Stachytarphetae Jamaicensis: have heat-clearing and toxic substances removing, the function of relieving stranguria by diuresis;
Semen Maydis: the function with relieving stranguria by diuresis, jaundice eliminating detumescence;
Folium Pyrrosiae: the function with heat clearing away, relieving stranguria by diuresis;
Stone Bufo siccus: the function with expelling wind and removing dampness, inducing diuresis for treating stranguria syndrome;
Cacumen Securinegae Suffruticosae: the function with liver heat removing and eyesight improving, eliminating dampness and diuresis;
Herba Marsileae Quadrifoliae: have inducing diuresis to remove edema, the function of calming the nerves;
Boehmeria: the function with hemostasis, heat-clearing and toxic substances removing;
Herba Melicae Scabrosae: the function with relieving stranguria by diuresis, clearing away heat and cooling blood;
Herba Lysimachiae: the function with heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, dampness removing jaundice eliminating;
JINSUOSHI: the function with clearing away heat and promoting diuresis, expelling wind and removing dampness;
Herba lygodii: the function with heat clearing away, relieving stranguria by diuresis;
Herba clerodendranthi spicati: the function with clearing heat and removing internal wetness, calculus diuretic;
Herba Lophatheri: the function with clearing away heat and promoting diuresis;
Herba Desmodii Triquetri (Herba Tadehagi Triquetri): the function with heat-clearing and toxic substances removing, removing food stagnancy dampness removing;
So all material medicines share among the present invention, can be so that the meridians in the patient body be unimpeded, with be hidden in the wind in patient's the five internal organs, cold, wet three poison are discharged, and are discharged unnecessary hydrops in the kidney, the five internal organs in the balance patient body, thoroughly cure patient's uremia, also the energetic physique of patient.
In addition, the used material medicine of the present invention is pure Chinese herbal medicine, and its cost is very low with respect to general uremia's medicine, concerning most of low-income groups, all can accept economically.So medicine of the present invention can reduce cost widely.
Medicine of the present invention shows all that in the zoopery of two kinds of Renal Failure Models of Big and Little Rats it has the serum creatinine of falling, blood urea nitrogen, improves the effect of renal function.
In order to embody better the therapeutic effect of medicine of the present invention, following table has provided two groups of curative effect data using medicine of the present invention to treat and use conventional medicine to treat, and is specific as follows:
(wherein the A group is the curative effect data of using medicine of the present invention to treat, the B group is the curative effect data of using conventional medicine to treat, the NIAODUQING that the conventional medicine that wherein adopts is selected to be produced by Guangzhou Kang Chen pharmaceutical factory is the primary treatment medicine, is aided with the other drug component).
As seen from the above table, medicine of the present invention has more outstanding effect at treatment uremic prescription mask.Through clinical proof, when using medicine of the present invention that the patient is treated, convenient oral only needed to cure in 3～5 months.Come explanation to the curative effect of medicine of the present invention below in conjunction with two model cases:
Model case 1: yellow surname personage, man, 65 years old, civil servant, anuria can not be interrupted through thoroughly accepting treatment for medical treatment in hospital because the extremity edema appears in uremia in 1998, and bring into use medicine of the present invention to treat in March, 1999, to symptom elimination in May, various indexes are normal, and physical recovery is normal.
Model case 2: prunus mume (sieb.) sieb.et zucc. surname personage, the woman, 68 years old, the resident because of the extremity edema, was uremia through hospital diagnosis, brings into use medicine of the present invention to treat March calendar year 2001, to recovery from illness in July calendar year 2001, so far not recurrence.
The specific embodiment
Embodiment one:
In the present embodiment, medicine of the present invention is comprised of following weight proportion: Rhizoma Saururi (Herba Saururi) 5 grams; Dodder laurel 8 grams; Radix Cocculi Orbiculati 5 grams; Caulis Akebiae 5 grams; Herba Plantaginis 8 grams; Herba Stachytarphetae Jamaicensis 9 grams; Semen Maydis 15 grams; Folium Pyrrosiae 9 grams; Stone Bufo siccus 5 grams; Cacumen Securinegae Suffruticosae 9 grams; Herba Marsileae Quadrifoliae 9 grams; Boehmeria 9 grams; Herba Melicae Scabrosae 15 grams; Herba Lysimachiae 9 grams; JINSUOSHI 9 grams; Herba lygodii 12 grams; Herba clerodendranthi spicati 15 grams; Herba Lophatheri 9 grams; Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 15 grams.
The preparation method of medicine of the present invention comprises the steps:
(1) gets Rhizoma Saururi (Herba Saururi) 5 grams, dodder laurel 8 grams, Radix Cocculi Orbiculati 5 grams, Caulis Akebiae 5 grams, Herba Plantaginis 8 grams, Herba Stachytarphetae Jamaicensis 9 grams, Semen Maydis 15 grams, Folium Pyrrosiae 9 grams, Herba Marsileae Quadrifoliae 9 grams, Herba Melicae Scabrosae 15 grams, Herba Lysimachiae 9 grams, Herba clerodendranthi spicati 15 grams, Herba Lophatheri 9 grams, Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 15 grams, be positioned in the iron pan, fry to faint yellow with 50 ℃～90 ℃ low temperature, be ground into again fine powder, the rear mixing that sieves, for subsequent use;
(2) get stone Bufo siccus 5 grams, Cacumen Securinegae Suffruticosae 9 grams, Boehmeria 9 grams, JINSUOSHI 9 grams, Herba lygodii 12 grams, Steam by water bath is 5～9 minutes respectively, and it is air-dry then to be put in shady and cool place, be positioned over again in the iron pan, fry to faint yellow with 50 ℃～90 ℃ low temperature, and be ground into fine powder, the rear mixing that sieves, for subsequent use;
(3) get above-mentioned steps (1) gained fine powder, above-mentioned steps (2) gained fine powder mixing, in incapsulating, make capsule.
Or get above-mentioned steps (1) gained fine powder, above-mentioned steps (2) gained fine powder mixing, compacting also coating in blocks is made tablet;
Or get above-mentioned steps (1) gained fine powder, above-mentioned steps (2) gained fine powder mixing, granulate drying, granulate, granulation agent;
Or get above-mentioned steps (1) gained fine powder, above-mentioned steps (2) gained fine powder mixing, make pill.
Embodiment two:
In the present embodiment, medicine of the present invention is comprised of following weight proportion: Rhizoma Saururi (Herba Saururi) 19 grams; Dodder laurel 15 grams; Radix Cocculi Orbiculati 12 grams; Caulis Akebiae 15 grams; Herba Plantaginis 19 grams; Herba Stachytarphetae Jamaicensis 21 grams; Semen Maydis 25 grams; Folium Pyrrosiae 15 grams; Stone Bufo siccus 9 grams; Cacumen Securinegae Suffruticosae 15 grams; Herba Marsileae Quadrifoliae 15 grams; Boehmeria 15 grams; Herba Melicae Scabrosae 25 grams; Herba Lysimachiae 15 grams; JINSUOSHI 15 grams; Herba lygodii 25 grams; Herba clerodendranthi spicati 25 grams; Herba Lophatheri 15 grams; Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 25 grams.
The preparation method of medicine of the present invention comprises the steps:
(1) gets Rhizoma Saururi (Herba Saururi) 19 grams, dodder laurel 15 grams, Radix Cocculi Orbiculati 12 grams, Caulis Akebiae 15 grams, Herba Plantaginis 19 grams, Herba Stachytarphetae Jamaicensis 21 grams, Semen Maydis 25 grams, Folium Pyrrosiae 15 grams, Herba Marsileae Quadrifoliae 15 grams, Herba Melicae Scabrosae 25 grams, Herba Lysimachiae 15 grams, Herba clerodendranthi spicati 25 grams, Herba Lophatheri 15 grams, Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 25 grams, be positioned in the iron pan, fry to faint yellow with 50 ℃～90 ℃ low temperature, be ground into again fine powder, the rear mixing that sieves, for subsequent use;
(2) get stone Bufo siccus 5 grams, Cacumen Securinegae Suffruticosae 9 grams, Boehmeria 9 grams, JINSUOSHI 9 grams, Herba lygodii 12 grams, Steam by water bath is 5～9 minutes respectively, and it is air-dry then to be put in shady and cool place, be positioned over respectively again in the iron pan, fry to faint yellow with 50 ℃～90 ℃ low temperature, and be ground into fine powder, the rear mixing that sieves, for subsequent use;
(3) get above-mentioned steps (1) gained fine powder, above-mentioned steps (2) gained fine powder mixing, in incapsulating, make capsule.
Or get above-mentioned steps (1) gained fine powder, above-mentioned steps (2) gained fine powder mixing, compacting also coating in blocks is made tablet;
Or get above-mentioned steps (1) gained fine powder, above-mentioned steps (2) gained fine powder mixing, granulate drying, granulate, granulation agent;
Or get above-mentioned steps (1) gained fine powder, above-mentioned steps (2) gained fine powder mixing, make pill.
Embodiment three:
In the present embodiment, medicine of the present invention is comprised of following weight proportion: Rhizoma Saururi (Herba Saururi) 12 grams; Dodder laurel 12 grams; Radix Cocculi Orbiculati 9 grams; Caulis Akebiae 10 grams; Herba Plantaginis 14 grams; Herba Stachytarphetae Jamaicensis 15 grams; Semen Maydis 20 grams; Folium Pyrrosiae 12 grams; Stone Bufo siccus 7 grams; Cacumen Securinegae Suffruticosae 12 grams; Herba Marsileae Quadrifoliae 12 grams; Boehmeria 12 grams; Herba Melicae Scabrosae 20 grams; Herba Lysimachiae 12 grams; JINSUOSHI 12 grams; Herba lygodii 19 grams; Herba clerodendranthi spicati 20 grams; Herba Lophatheri 12 grams; Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 20 grams.
The preparation method of medicine of the present invention comprises the steps:
(1) gets Rhizoma Saururi (Herba Saururi) 12 grams, dodder laurel 12 grams, Radix Cocculi Orbiculati 9 grams, Caulis Akebiae 10 grams, Herba Plantaginis 14 grams, Herba Stachytarphetae Jamaicensis 15 grams, Semen Maydis 20 grams, Folium Pyrrosiae 12 grams, Herba Marsileae Quadrifoliae 12 grams, Herba Melicae Scabrosae 20 grams, Herba Lysimachiae 12 grams, Herba clerodendranthi spicati 20 grams, Herba Lophatheri 12 grams, Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 20 grams, be positioned in the iron pan, fry to faint yellow with 50 ℃～90 ℃ low temperature, be ground into again fine powder, the rear mixing that sieves, for subsequent use;
(2) get stone Bufo siccus 7 grams, Cacumen Securinegae Suffruticosae 12 grams, Boehmeria 12 grams, JINSUOSHI 12 grams, Herba lygodii 19 grams, Steam by water bath is 5～9 minutes respectively, then it is air-dry to be put in shady and cool place, be positioned over respectively in the iron pan again, fry to faint yellow with 50 ℃～90 ℃ low temperature, and be ground into fine powder, and the rear mixing that sieves, for subsequent use;
(3) get above-mentioned steps (1) gained fine powder, above-mentioned steps (2) gained fine powder mixing, in incapsulating, make capsule.
Or get above-mentioned steps (1) gained fine powder, above-mentioned steps (2) gained fine powder mixing, compacting also coating in blocks is made tablet;
Or get above-mentioned steps (1) gained fine powder, above-mentioned steps (2) gained fine powder mixing, granulate drying, granulate, granulation agent;
Or get above-mentioned steps (1) gained fine powder, above-mentioned steps (2) gained fine powder mixing, make pill.
Claims (2)
1. the uremic medicine for the treatment of is characterized in that, described a kind of to treat uremic medicine be to be made by the material medicine of following weight portion:
Rhizoma Saururi (Herba Saururi) 5～19 dodder laurels 8～15 Radix Cocculi Orbiculati 5～12
Caulis Akebiae 5～15 Herba Plantaginiss 8～19 Herba Stachytarphetae Jamaicensiss 9～21
Semen Maydis 15～25 Folium Pyrrosiaes 9～15 stone Bufo siccuss 5～9
Cacumen Securinegae Suffruticosae 9～15 Herba Marsileae Quadrifoliaes 9～15 Boehmeria 9～15
Herba Melicae Scabrosae 15～25 Herba Lysimachiaes 9～15 JINSUOSHI 9～15
Herba lygodii 12～25 Herba clerodendranthi spicati 15～25 Herba Lophatheris 9～15
Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 15～25.
2. preparation method that is used for the treatment of uremic medicine claimed in claim 1 is characterized in that the method may further comprise the steps:
(1) Rhizoma Saururi (Herba Saururi), dodder laurel, Radix Cocculi Orbiculati, Caulis Akebiae, Herba Plantaginis, Herba Stachytarphetae Jamaicensis, Semen Maydis, Folium Pyrrosiae, Herba Marsileae Quadrifoliae, Herba Melicae Scabrosae, Herba Lysimachiae, Herba clerodendranthi spicati, Herba Lophatheri, the Herba Desmodii Triquetri (Herba Tadehagi Triquetri) with described weight proportion is positioned in the iron pan, fry to faint yellow with low temperature, be ground into again fine powder, the rear mixing that sieves, for subsequent use;
(2) with the stone Bufo siccus of described weight proportion, JINSUOSHI, Herba lygodii, Cacumen Securinegae Suffruticosae, Boehmeria Steam by water bath 5～9 minutes respectively, it is air-dry then to be put in shady and cool place, is positioned in the iron pan again, and fry to faint yellow with low temperature, and be ground into fine powder, the rear mixing that sieves, for subsequent use;
(3) get above-mentioned steps (1) gained fine powder, above-mentioned steps (2) gained fine powder mixing, in incapsulating, make capsule.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110045458 CN102106980B (en) | 2011-02-25 | 2011-02-25 | Medicament for treating uremia and preparation method thereof |
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| CN 201110045458 CN102106980B (en) | 2011-02-25 | 2011-02-25 | Medicament for treating uremia and preparation method thereof |
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| CN102106980A CN102106980A (en) | 2011-06-29 |
| CN102106980B true CN102106980B (en) | 2013-04-17 |
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| CN103272140B (en) * | 2013-06-20 | 2015-07-29 | 周义 | Control uremic medicine and preparation method thereof |
| CN103535474A (en) * | 2013-09-05 | 2014-01-29 | 林建成 | Health-care tea and preparation method thereof |
| CN103636861A (en) * | 2013-11-29 | 2014-03-19 | 王洪平 | Skin-nourishing and calculi-eliminating tea |
| CN113181302A (en) * | 2021-06-10 | 2021-07-30 | 林莹瑶 | Traditional Chinese medicine for treating nephritis |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101053616A (en) * | 2006-04-13 | 2007-10-17 | 陈见民 | Medicine for treating uremia |
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| CN101053616A (en) * | 2006-04-13 | 2007-10-17 | 陈见民 | Medicine for treating uremia |
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