CN101052630A - 取代的杂环化合物和其用途 - Google Patents

取代的杂环化合物和其用途 Download PDF

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Publication number
CN101052630A
CN101052630A CNA2005800377045A CN200580037704A CN101052630A CN 101052630 A CN101052630 A CN 101052630A CN A2005800377045 A CNA2005800377045 A CN A2005800377045A CN 200580037704 A CN200580037704 A CN 200580037704A CN 101052630 A CN101052630 A CN 101052630A
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substituted
unsubstituted
nhc
compound
disease
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Chinese (zh)
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乔治·W·穆勒
汉华·曼
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Celgene Corp
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Celgene Corp
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    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • C07D209/04—Indoles; Hydrogenated indoles
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    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
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    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring

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  • Virology (AREA)
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  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
CNA2005800377045A 2004-09-03 2005-08-31 取代的杂环化合物和其用途 Pending CN101052630A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60740804P 2004-09-03 2004-09-03
US60/607,408 2004-09-03

Publications (1)

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CN101052630A true CN101052630A (zh) 2007-10-10

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US (2) US7468446B2 (enExample)
EP (1) EP1794139A2 (enExample)
JP (1) JP2008512378A (enExample)
KR (1) KR20070050987A (enExample)
CN (1) CN101052630A (enExample)
AR (1) AR050557A1 (enExample)
AU (1) AU2005282727A1 (enExample)
BR (1) BRPI0514857A (enExample)
CA (1) CA2578789A1 (enExample)
IL (1) IL181677A0 (enExample)
WO (1) WO2006028963A2 (enExample)
ZA (1) ZA200702380B (enExample)

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Publication number Priority date Publication date Assignee Title
CN109851601A (zh) * 2019-03-29 2019-06-07 吉首大学 一种含氰基苯并呋喃的合成方法和用途
CN113527400A (zh) * 2013-04-17 2021-10-22 萨奇治疗股份有限公司 19-去甲c3,3-二取代的c21-n-吡唑基类固醇及其使用方法

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US10767164B2 (en) 2017-03-30 2020-09-08 The Research Foundation For The State University Of New York Microenvironments for self-assembly of islet organoids from stem cells differentiation
CN107149005B (zh) * 2017-04-18 2021-05-04 安徽农业大学 一种红茶菌戊聚糖奶片的制备方法
CN115286562B (zh) * 2022-08-18 2024-02-23 青海大学 含有富电子的芳杂环或芳胺类化合物的苯甲酰化方法

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113527400A (zh) * 2013-04-17 2021-10-22 萨奇治疗股份有限公司 19-去甲c3,3-二取代的c21-n-吡唑基类固醇及其使用方法
CN109851601A (zh) * 2019-03-29 2019-06-07 吉首大学 一种含氰基苯并呋喃的合成方法和用途

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CA2578789A1 (en) 2006-03-16
EP1794139A2 (en) 2007-06-13
WO2006028963A3 (en) 2006-11-09
BRPI0514857A (pt) 2008-05-06
AU2005282727A1 (en) 2006-03-16
IL181677A0 (en) 2007-07-04
ZA200702380B (en) 2008-09-25
JP2008512378A (ja) 2008-04-24
AR050557A1 (es) 2006-11-01
US7468446B2 (en) 2008-12-23
KR20070050987A (ko) 2007-05-16
WO2006028963A2 (en) 2006-03-16
US20090042875A1 (en) 2009-02-12

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