CN101032539A - 复方平卧菊三七口腔喷雾剂 - Google Patents
复方平卧菊三七口腔喷雾剂 Download PDFInfo
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Abstract
本发明公开了一种复方平卧菊三七口腔喷雾剂，含有0.1～20％平卧菊三七提取物，0.1～1％钾硝唑，0.1～1％叶绿素钠盐，0.1～2％薄荷油，0.1～2％薄荷脑，该喷雾剂能抗菌、消炎、止痛、除口臭，并对口腔、牙齿、咽喉具有辅助治疗作用。
Description
技术领域
本发明涉及口腔保健、抗菌消炎用品，尤其是一种复方平卧菊三七口腔喷雾剂。
背景技术
目前，市面上销售的口腔喷雾剂种类很多，功能各异，同时也有不少中草药口腔喷雾剂。中草药-平卧菊三七是菊科、三七属植物、蛇接骨、Gynuraprocumbcns(Lour)morr，为多年生草本药食两用植物，别名也叫平卧土三七，民间用此植物治疗跌打损伤、风湿性关节炎、支气管炎、肺炎、肾炎等疾病；《中华本草》记载平卧菊三七能通经活络、散淤消肿，对支气管炎、肺炎、肺结核、肿毒痛疮有很好的疗效。近年来，国外发现该植物对急性感冒、皮疹、肾病、高血压、糖尿病有较好的疗效。
发明内容
本发明的目的就是提供一种能抗菌、消炎、止痛、除口臭，并对口腔、牙齿、咽喉具有辅助治疗作用的复方平卧菊三七口腔喷雾剂。
本发明的复方平卧菊三七口腔喷雾剂由以下重量百分比的原料组分组成：
平卧菊三七提取物 1～20％ 薄荷油 0.1～2％
钾硝唑 0.1～2％ 薄荷脑 0.1～2％
叶绿素钠盐 0.1～1％ 水 余 量。
本发明最好添加5～10％(重量)的平卧菊三七提取物。
所述的平卧菊三七提取物的制作方法是：将平卧菊三七全草粗粉加入8～10倍量的浓度为80～95％的乙醇中，回流提取2～4小时，将乙醇提取液回收乙醇至无醇味，得到平卧菊三七提取物。
本发明的复方平卧菊三七口腔喷雾剂制作方法是：将上述各原料组分通过溶解、搅拌、混匀，调节PH值至6，输进贮存罐，冷却贮存24小时，过滤，灌装，封口包装，检验到成品。
对平卧菊三七提取物进行化学成分的研究表明：平卧菊三七含有各种挥发油、黄硐苷、生物碱、有机酸(氯原酸及其衍生物3～5-双氧-咖啡酰奎宁酸和4～5-双氧-咖啡酰奎宁酸)和羟基乳酸等多种化学成分。
药理实验表明：平卧菊三七有机酸对由滤过性病原体引起的疱症、皮疹等有较好的治疗作用。而黄硐类成分：山奈酚-3-O-葡萄糖苷、柙皮素、-3-O-鼠李糖(1-6)葡萄糖苷、皮素、-3-O-鼠李糖(1-6)半乳糖苷、山奈酚-3-O-鼠李糖(1-6)葡萄糖苷等具有较好的修复胰脏β细胞和降低血糖浓度的显著作用，其生物碱类成分具有较强的抗菌止痛作用。
平卧菊三七提取物的体外抑菌试验表明：平卧菊三七对金黄色葡萄球菌及耐药菌株、痢疾杆菌、伤寒杆菌、副伤寒杆菌、大肠杆菌、绿浓杆菌等均有不同程度的抑制作用。同时对乙肝病毒、流感病毒有较好的抗病毒作用。
本发明的复方平卧菊三七口腔喷雾剂能抗菌、消炎、止痛、除口臭，并对口腔、牙齿、咽喉具有辅助治疗作用。
具体实施方式
实施例1：
一种复方平卧菊三七口腔喷雾剂由以下原料组分组成：
平卧菊三七提取物 5.5公斤 薄荷油 0.5公斤
钾硝唑 1.4公斤 薄荷脑 0.5公斤
叶绿素钠盐 0.1公斤 水 92公斤。
其制作方法是：将上述各组分通过溶解、搅拌、混匀，调节PH值至6，输进贮存罐，冷却贮存24小时，过滤，灌装，封口包装，检验到成品
实施例2：
一种复方平卧菊三七口腔喷雾剂由以下原料组分组成：
平卧菊三七提取物 8公斤 薄荷油 0.6公斤
钾硝唑 0.8公斤 薄荷脑 0.4公斤
叶绿素钠盐 0.2公斤 水 90公斤。
其制作方法与实施例1相同。
Claims (3)
1、一种复方平卧菊三七口腔喷雾剂，其特征在于：它是由以下重量百分比的原料组成：
平卧菊三七提取物 1～20％ 薄荷油 0.1～2％
钾硝唑 0.1～2％ 薄荷脑 0.1～2％
叶绿素钠盐 0.1～1％ 水 余量。
2、根据权利要求1所述的复方平卧菊三七口腔喷雾剂，其特征在于：所述的平卧菊三七提取物的制作方法是：将平卧菊三七全草粗粉加入8～10倍量的浓度为80～95％的乙醇中，回流提取2～4小时，将乙醇提取液回收乙醇至无醇味，得到平卧菊三七提取物。
3、根据权利要求1所述的复方平卧菊三七口腔喷雾剂，其特征在于：所述的平卧菊三七提取物重量百分比为5～10％。
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200710051827A CN101032539B (zh) | 2007-04-08 | 2007-04-08 | 复方平卧菊三七口腔喷雾剂 |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200710051827A CN101032539B (zh) | 2007-04-08 | 2007-04-08 | 复方平卧菊三七口腔喷雾剂 |
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| Publication Number | Publication Date |
|---|---|
| CN101032539A true CN101032539A (zh) | 2007-09-12 |
| CN101032539B CN101032539B (zh) | 2010-05-19 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN200710051827A Expired - Fee Related CN101032539B (zh) | 2007-04-08 | 2007-04-08 | 复方平卧菊三七口腔喷雾剂 |
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| CN (1) | CN101032539B (zh) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016010340A1 (ko) * | 2014-07-14 | 2016-01-21 | 박창용 | 오풍칠 추출물을 유효성분으로 함유하는 염증 또는 알러지 질환의 예방 및 치료용 조성물 및 이의 용도 |
| CN105395624A (zh) * | 2014-08-18 | 2016-03-16 | 刘桐言 | 一种独活止牙痛喷雾剂 |
| RU2618889C1 (ru) * | 2016-06-29 | 2017-05-11 | Виа Вита Эстейт Лимитед, регистрационный номер НЕ 141297 | Средство, обладающее противовоспалительным, антимикробным, ранозаживляющим действием, для полоскания полости рта |
| WO2018001391A1 (en) * | 2016-06-28 | 2018-01-04 | Grigoriou Kostas | A gynura procumbens oil solution for the treatment of peripheral diabetic polyneuritis, tendinopathies, gingivitis and periodontitis and its process therof |
| CN112675260A (zh) * | 2020-12-30 | 2021-04-20 | 江西省科学院应用化学研究所 | 一种抑制口臭的平卧菊三七含片及其制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1270803A (zh) * | 1999-04-19 | 2000-10-25 | 蔡东明 | 复方草珊瑚口腔喷雾剂 |
-
2007
- 2007-04-08 CN CN200710051827A patent/CN101032539B/zh not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016010340A1 (ko) * | 2014-07-14 | 2016-01-21 | 박창용 | 오풍칠 추출물을 유효성분으로 함유하는 염증 또는 알러지 질환의 예방 및 치료용 조성물 및 이의 용도 |
| CN105395624A (zh) * | 2014-08-18 | 2016-03-16 | 刘桐言 | 一种独活止牙痛喷雾剂 |
| WO2018001391A1 (en) * | 2016-06-28 | 2018-01-04 | Grigoriou Kostas | A gynura procumbens oil solution for the treatment of peripheral diabetic polyneuritis, tendinopathies, gingivitis and periodontitis and its process therof |
| RU2618889C1 (ru) * | 2016-06-29 | 2017-05-11 | Виа Вита Эстейт Лимитед, регистрационный номер НЕ 141297 | Средство, обладающее противовоспалительным, антимикробным, ранозаживляющим действием, для полоскания полости рта |
| CN112675260A (zh) * | 2020-12-30 | 2021-04-20 | 江西省科学院应用化学研究所 | 一种抑制口臭的平卧菊三七含片及其制备方法 |
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| Publication number | Publication date |
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| CN101032539B (zh) | 2010-05-19 |
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