CN101020005A

CN101020005A - Oral medicine for treating dizziness and its prepn

Info

Publication number: CN101020005A
Application number: CN 200710051531
Authority: CN
Inventors: 秦建华
Original assignee: Individual
Current assignee: Individual
Priority date: 2007-02-09
Filing date: 2007-02-09
Publication date: 2007-08-22

Abstract

The present invention relates to one kind of oral medicine for treating dizziness and its preparation process. The oral medicine is prepared with the Chinese medicinal materials, including gastrodia tuber 10-15 weight portions, red sage 10-15 weight portions, tribulus terrestris 10-15 weight portions, altai anemone rhizome 7-9 weight portions, and pulp of dogwood fruit 7-9 weight portions. It can improve brain blood supply, improve spasm and treating dizziness, and has the advantages of high safety, less side effect, high curative effect, etc.

Description

A kind of oral medicine for the treatment of dizzy giddy and preparation method thereof

Technical field

The present invention relates to a kind of oral medicine for the treatment of dizzy giddy and preparation method thereof.

Background technology

Dizzy, claim again " Menieres disease ", the ataxia that pathogenic factor causes mainly due to interior auricularis edema, the patient feels day to revolve confusedly during morbidity, and nausea and vomiting, photophobia, inactive in the time of seriously are moving then also very; The men and women all can fall ill, and every and tired, morbidity easily repeatedly, does not still have the radical cure way at present when depressed.Dizzy headache, its pathogenic factor is a lot, and the blood supply in brain deficiency is its main cause, and causes that the insufficient reason of blood supply in brain is also a lot; As cerebral arteriosclerosis, cerebral vasospasm, cerebral arteries deformity etc. is its main pathogenic factor.The traditional Chinese medical science is said: " calm do not do dizzy ", " no expectorant is not done to swoon ", and brain is the mansion in Clear and Bright, kidney master marrow leads in brain, and is therefore dizzy, dizzy, have a headache due to all liver-wind is suffered from a deficiency of the kidney, benefiting essence and marrow, it is to treat this sick fundamental law that suppressing the hyperactive liver dispels the wind.

Summary of the invention

The object of the present invention is to provide a kind of oral medicine for the treatment of dizzy giddy and preparation method thereof.

Technical scheme of the present invention is:

A kind ofly treat dizzy, dizzy endo-medicine, it is characterized in that: it is the medicament of being made by the following weight proportion raw material: Rhizoma Gastrodiae 10-15 part, Radix Salviae Miltiorrhizae 10-15 part, Fructus Tribuli 10-15 part, Rhizoma Anemones Altaicae 7-9 part, Fructus Corni 7-9 part.

Treat dizzy, dizzy endo-medicine, it is characterized in that: it is the medicament of being made by the following weight proportion raw material: Rhizoma Gastrodiae 12-15 part, Radix Salviae Miltiorrhizae 12-15 part, Fructus Tribuli 12-15 part, Rhizoma Anemones Altaicae 6-8 part, Fructus Corni 6-8 part.

Treat dizzy, dizzy endo-medicine, it is characterized in that: it is the medicament of being made by the following weight proportion raw material: 15 parts in Rhizoma Gastrodiae, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of Fructus Tribulis, 8 parts of Rhizoma Anemones Altaicaes, 8 parts of Fructus Corni.

The consumption and the course of treatment: curative effect of the present invention diagnosis does not still have clear and definite standard, and generally be according to the disappearance of symptom or improve as foundation, according to the length of the course of disease, the weight of symptom, or single " dizzy " " giddy " or difference that the two haves both at the same time.In the medication process, each patient's the course of treatment is inequality, varies with each individual, and medication is arranged 1 day, and 3 days, 7 days, 30 days difference was a course of treatment with three days generally.Vertigo general course of treatment; The dizzy headache 3-4 the course of treatment, course of disease person repeatedly can be taken 30 days continuously, and therefore the result who draws from clinical practice the course of treatment of the present invention was advisable for 6-30 days.

Observation index:

1, symptom: giddy, look thing rotation, the companion feels sick, vomiting, tinnitus, nystagmus, limb fiber crops, uncomfortable in chest vexed, dizzy, have a headache.

2, untoward reaction: any untoward reaction that occurs during the treatment is recorded faithfully.

Curative effect is judged:

1 disease evaluation criterion

1.1 it is dizzy, look the thing rotation

1.2 dizzy, headache

1.3 nauseating, vomiting

1.4 tinnitus, nystagmus

1.5 limb fiber crops, weak

1.6 it is uncomfortable in chest vexed

1.7 dizzy, headache

Above symptom is remembered 1 fen respectively, public 6 minutes.

2 curative effect judging standards

2.1 recovery from illness: symptom all disappears, and does not see the recidivist more than 1 year.

2.2 produce effects: dizzy, headgear, look thing rotation and simultaneous phenomenon disappearance or appearance once in a while, treatment back integration descends greater than 2/3.

2.3 effectively: dizzy, look the thing rotation, dizzy, times of headache reduces, simultaneous phenomenon disappears substantially, treatment back integration drops to 2/3,1/3.

2.4 invalid: dizzy, look thing rotation, dizzy, times of headache and simultaneous phenomenon and do not subtract, treatment back integration descends 1/3.

3 clinical effectiveness:

The clinical therapeutic efficacy statistics

Illustrate: therapist all is under the invalid situation of various medicines for oral administration, uses the embodiment of the invention 1 used medicine to treat, and is divided into four groups by symptom different random such as dizzy, dizzy, headaches, and its result as above.Matched group is not taken this medicine, and the Thebe of adopting medicine Xi'an Janssen Pharmaceutica factory to produce is peaceful, every day 2 times, and each 5mg, 5 days is one-period.

According to the result of clinical treatment as can be seen, curative effect of the present invention is still very definite, and as for invalid, mainly based on Algopsychalia, and the course of disease itself is very long, and the treatment difficulty is bigger.

Medical record is given an example:

Example 1: San Wei village, the Jiang Xiang of Nanchang County town women student one people.25 years old, the city defended the school graduation in 2000, and just often sexy dizzy, dizzy when defending the proofreading book, as carsickness, annual outbreak 2-3 time does not need medication, as long as just the spontaneous remission in 1-2 days of taking a quick nap during outbreak.The private hospital manual labour in Zhuhai in 2004, consider because of work labor during this time, outbreak is frequent, and the sense sky is dizzy confusedly during recurrence, companion's nausea and vomiting, photophobia, inactive, moving then also very, must the drop glucose, aminoacid etc. still can alleviate in one week of medicine, arrived provinces and cities' hospitalize once, be diagnosed as " Meniere's disease ".Outbreak in patient 2-30 days once, symptom can't be improved, and, takes " dizzy pain is relaxed " 3 days transference cures in mid-April, 2005 here treatment, take 9 days one as usual, Zhuhai recurrence of doing manual work so far now.

Example 2: son peace road one people of Nanchang City, women, 49 years old, professional accounting.The giddy 2-3 when the time comes that suffers from headaches used medicines such as the Thebe is peaceful, breviscapine, Fructus Liquidambaris, rheoencephalogram prompting " cerebral vasospasm ", accept " dizzy pain is relaxed " treatment on May 16th, 2006, take 3 days doing well,improvings, symptom disappears entirely after 6 days, check rheoencephalogram behind the first quarter moon, all are normal.

Example 3: Nanchang City's retirement veteran cadre one people, the male, 80 years old, suffer from dizzy headache and last 20 years, is cerebral arteriosclerosis at provincial hospital through EEG (electrocardiogram) examination, uses successively that the Thebe is peaceful, breviscapine etc. is invalid, takes on November 20th, 2006 " dizzy pain is relaxed ", symptom disappears entirely after three days, and drug withdrawal is not recurrence so far.

Example 4: No. 519 one people in ship hill path, Nanchang City, the women 53 years old, suffers from dizzy lasting more than 10 years, do brain magnetic resonance inspection prompting cerebral arteries deformity economizing an attached institute, successively used medicines such as the Thebe is peaceful, breviscapine, ZHENNAONING, Folium Ginkgo invalid, and accepted " dizzy pain is relaxed " treatment on November 8th, 2006, taking 2 days symptoms promptly improves, intermittently take now always, the patient does not feel like oneself voluntarily after drug withdrawal 2-3 days, therefore just takes whenever doing not feel like oneself, and adheres to so far.

The invention has the advantages that: security performance for oral administration is strong, and curative effect is great advantage of the present invention soon, and relatively littler to the toxic and side effects probability that human body brings with other oral medicine, this also is the common sensation of patient.The patient does not take untoward reaction such as the regurgitation, flatulence of this medicine, and from clinical, curative effect is fast, and remission is difficult for repeatedly, and short treating period is cheap.The limited brain blood supply that improves of the present invention's energy improves spasm, treats dizzy giddy.

The specific embodiment

Embodiment 1, dizzy, the dizzy endo-medicine of treatment, wherein: it is the medicament of being made by the following weight proportion raw material: Rhizoma Gastrodiae 10-15 part, Radix Salviae Miltiorrhizae 10-15 part, Fructus Tribuli 10-15 part, Rhizoma Anemones Altaicae 7-9 part, Fructus Corni 7-9 part.

Embodiment 2, dizzy, the dizzy endo-medicine of treatment, wherein: it is the medicament of being made by the following weight proportion raw material: Rhizoma Gastrodiae 12-15 part, Radix Salviae Miltiorrhizae 12-15 part, Fructus Tribuli 12-15 part, Rhizoma Anemones Altaicae 6-8 part, Fructus Corni 6-8 part.

Embodiment 3, dizzy, the dizzy endo-medicine of treatment, wherein: it is the medicament of being made by the following weight proportion raw material: 15 parts in Rhizoma Gastrodiae, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of Fructus Tribulis, 8 parts of Rhizoma Anemones Altaicaes, 8 parts of Fructus Corni.

The preparation method of embodiment 4, dizzy, the dizzy endo-medicine of treatment, wherein: get Rhizoma Gastrodiae by weight ratio, Radix Salviae Miltiorrhizae, Fructus Tribuli, Rhizoma Anemones Altaicae, the crude drug that Fructus Corni is formed amounts to 1000g, prepares by following method: the pretreatment of A crude drug: with Rhizoma Gastrodiae, and Radix Salviae Miltiorrhizae, Fructus Tribuli, Rhizoma Anemones Altaicae, Fructus Corni cleans up respectively, the Rhizoma Gastrodiae shave; B decocts: add 7000 ml waters for the first time and decocted 2 hours, filter time medicinal liquid of winning; Add for the second time 3000 ml waters decoct filtered in 1 hour medicinal liquid for the second time, the secondary medicinal liquid merges to concentrate and concentrates; Can be packed as oral liquid when being concentrated into 625 milliliters.All the other are with embodiment 3.

The preparation method of embodiment 5, dizzy, the dizzy endo-medicine of treatment, wherein: oral liquid is continued to concentrate, to proportion be 1.12 o'clock, get 1 part of condensed cream, add 0.2 part of microcrystalline Cellulose, 0.5 part of low-substituted hydroxypropyl cellulose, 0.1 part of crospolyvinylpyrrolidone, add 3 parts of dissolvings of water, make soft material; 20 mesh sieves are made wet granular, drying, and 20 mesh sieve granulate, tabletting become tablet or the granule behind the granulate are filled in the capsule.All the other are with embodiment 4.

Embodiment 6, dizzy, the dizzy endo-medicine of treatment, wherein: it is the medicament of being made by the following weight proportion raw material: 10 parts in Rhizoma Gastrodiae, 15 parts of Radix Salviae Miltiorrhizaes, 10 parts of Fructus Tribulis, 9 parts of Rhizoma Anemones Altaicaes, 7 parts of Fructus Corni.All the other are with embodiment 3.

Embodiment 7, dizzy, the dizzy endo-medicine of treatment, wherein: it is the medicament of being made by the following weight proportion raw material: 15 parts in Rhizoma Gastrodiae, 10 parts of Radix Salviae Miltiorrhizaes, 15 parts of Fructus Tribulis, 7 parts of Rhizoma Anemones Altaicaes, 9 parts of Fructus Corni.All the other are with embodiment 3.

Embodiment 8, dizzy, the dizzy endo-medicine of treatment, wherein: it is the medicament of being made by the following weight proportion raw material: 12 parts in Rhizoma Gastrodiae, 15 parts of Radix Salviae Miltiorrhizaes, 12 parts of Fructus Tribulis, 6 parts of Rhizoma Anemones Altaicaes, 8 parts of Fructus Corni.All the other are with embodiment 4.

Embodiment 9, dizzy, the dizzy endo-medicine of treatment, wherein: it is the medicament of being made by the following weight proportion raw material: 15 parts in Rhizoma Gastrodiae, 12 parts of Radix Salviae Miltiorrhizaes, 15 parts of Fructus Tribulis, 8 parts of Rhizoma Anemones Altaicaes, 6 parts of Fructus Corni.All the other are with embodiment 4.

Embodiment 9, dizzy, the dizzy endo-medicine of treatment, wherein: it is the medicament of being made by the following weight proportion raw material: 13 parts in Rhizoma Gastrodiae, 13 parts of Radix Salviae Miltiorrhizaes, 14 parts of Fructus Tribulis, 7 parts of Rhizoma Anemones Altaicaes, 7 parts of Fructus Corni.All the other are with embodiment 4.

Claims

1, a kind ofly treat dizzy, dizzy endo-medicine, it is characterized in that: it is the medicament of being made by the following weight proportion raw material: Rhizoma Gastrodiae 10-15 part, Radix Salviae Miltiorrhizae 10-15 part, Fructus Tribuli 10-15 part, Rhizoma Anemones Altaicae 7-9 part, Fructus Corni 7-9 part.

2, dizzy, the dizzy endo-medicine of treatment according to claim 1, it is characterized in that: it is the medicament of being made by the following weight proportion raw material: Rhizoma Gastrodiae 12-15 part, Radix Salviae Miltiorrhizae 12-15 part, Fructus Tribuli 12-15 part, Rhizoma Anemones Altaicae 6-8 part, Fructus Corni 6-8 part.

3, dizzy, the dizzy endo-medicine of treatment according to claim 1 is characterized in that: it is the medicament of being made by the following weight proportion raw material: 15 parts in Rhizoma Gastrodiae, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of Fructus Tribulis, 8 parts of Rhizoma Anemones Altaicaes, 8 parts of Fructus Corni.

4, the preparation method of dizzy, the dizzy endo-medicine of the described treatment of claim 3, it is characterized in that: get Rhizoma Gastrodiae by weight ratio, Radix Salviae Miltiorrhizae, Fructus Tribuli, Rhizoma Anemones Altaicae, the crude drug that Fructus Corni is formed amounts to 1000g, prepares by following method: the pretreatment of A crude drug: with Rhizoma Gastrodiae, and Radix Salviae Miltiorrhizae, Fructus Tribuli, Rhizoma Anemones Altaicae, Fructus Corni cleans up respectively, the Rhizoma Gastrodiae shave; B decocts: add 7000 ml waters for the first time and decocted 2 hours, filter time medicinal liquid of winning; Add for the second time 3000 ml waters decoct filtered in 1 hour medicinal liquid for the second time, the secondary medicinal liquid merges to concentrate and concentrates; Can be packed as oral liquid when being concentrated into 625 milliliters.

5, the preparation method of dizzy, the dizzy endo-medicine of treatment according to claim 4, it is characterized in that: oral liquid is continued to concentrate, to proportion be 1.12 o'clock, get 1 part of condensed cream, add 0.2 part of microcrystalline Cellulose, 0.5 part of low-substituted hydroxypropyl cellulose, 0.1 part of crospolyvinylpyrrolidone, add 3 parts of dissolvings of water, make soft material; 20 mesh sieves are made wet granular, drying, and 20 mesh sieve granulate, tabletting become tablet or the granule behind the granulate are filled in the capsule.