CN101011558A - Antineoplastic, anti-cancer drugs - Google Patents
Antineoplastic, anti-cancer drugs Download PDFInfo
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- CN101011558A CN101011558A CNA2007100656561A CN200710065656A CN101011558A CN 101011558 A CN101011558 A CN 101011558A CN A2007100656561 A CNA2007100656561 A CN A2007100656561A CN 200710065656 A CN200710065656 A CN 200710065656A CN 101011558 A CN101011558 A CN 101011558A
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Abstract
The invention provides an antineoplastic and anti-cancer medicament which is prepared from the following raw materials (by mass ratio): notoginseng 300-700 parts, centipede 50-100 parts, caesalpinia seed 400-600 parts, pangolin scales 300-600 parts, Eupolyphaga Sinensis Walker 300-600 parts, Garter snake 400-500 parts, curcuma root 500-700 parts and aspongopus 200-300 parts.
Description
Technical field
The present invention relates to a kind of medicine, especially a kind of antitumor, anticancer pure Chinese medicine medicine.
Background technology
Tumor be body under various carcinogenic factor effects, the cellular abnormality hypertrophy of its local organization is formed, often show as local lump.Tumor cell changes from normal cell, after it becomes tumor cell, just has unusual form, metabolism and function, its growth is comparatively vigorous, and being endless relatively growth situation, it and whole machine body are extremely inharmonious, and have lost the fully-developed ability to some extent.With regard to present medical level, the diagnosis of various tumors, cancer has not been problem, but it is very difficult to tumor, treatment for cancer, owing to also do not develop the medicine that as broad-spectrum antibiotic, can generally kill cancerous cell now, so to most of tumor, cancer patient, can only carry out excision earlier, and then kill cancerous cell by X-ray therapy or chemotherapy, but these two kinds of methods also can be killed the normal healthy cell when killing cancerous cell, cause tumor, cancer patient's resistance and immunity degradation.Be the side effect of avoiding radiotherapy, chemotherapy to bring, the therapy for treatment of cancer that then adopts Chinese and western medicine to combine that has, but it is all not obvious to produce effects.Though the curing cancer drug of Chu Shouing has multiplely in the market, all have stronger specific aim, and curative effect also is limited.Therefore, be necessary to develop new curing cancer drug, to satisfy cancer patient's demand.
Summary of the invention
For overcoming resistance and the immunity degradation that existing radiotherapy, chemotherapy bring for tumor, cancer patient, even be difficult to deficiency such as radical cure, the invention provides a kind of evident in efficacy, pure Chinese medicine antitumor, cancer therapy drug that cure rate is high.
The present invention is according to traditional Chinese medical science oncology theory, the generation, development and the healthy energy that are tumor are lost empty, the spirit disorder of emotion, the exopathogen invasion, factors such as dietetic nutrition is unbalance are directly related, and are comparatively complicated at the tumor invasion cause of disease, and feature such as individual variation is bigger, from heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, remove disease eliminating stagnation, treating the poisonous disease with poisonous drugs, warming the meridian removing food stagnancy, set upright many aspects such as tonify deficiency and adjust treatment, in the hope of obtaining best therapeutic effect.
The present invention realizes by following technical proposal: a kind of antitumor, cancer therapy drug is characterized in that being made by the raw material of following mass parts:
Radix Notoginseng 300-700 part Scolopendra 0-100 part
Semen Caesalpiniae Minacis 400-600 part Squama Manis 300-600 part
Eupolyphaga Seu Steleophaga 300-600 part Zaocys 400-500 part
Radix Curcumae 500-700 part Aspongopus 200-300 part.
Described antitumor, cancer therapy drug, its preferable raw material by following mass parts is made:
Radix Notoginseng 400-600 part Scolopendra 60-80 part
Semen Caesalpiniae Minacis 500-600 part Squama Manis 400-600 part
Eupolyphaga Seu Steleophaga 400-600 part Zaocys 300-500 part
Radix Curcumae 500-600 part Aspongopus 200-300 part.
Described antitumor, cancer therapy drug, its best is made by the raw material of following mass parts:
70 parts of 500 parts of Scolopendras of Radix Notoginseng
500 parts of 500 parts of Squama Maniss of Semen Caesalpiniae Minacis
500 parts of 500 parts of Zaocys of Eupolyphaga Seu Steleophaga
200 parts of 600 portions of Aspongopuss of Radix Curcumae.
Wherein, cold in nature, the bitter in the mouth of Radix Notoginseng, energy hemostasis, dissipating blood stasis, detumescence, analgesic therapy, carbuncle pain.Scolopendra acrid in the mouth warm in nature, poisonous, energy expelling wind for relieving convulsion, counteracting toxic substances, diffusing buildup piece etc.Semen Caesalpiniae Minacis can eliminating stasis to stop pain, heat clearing away, dry.Squama Manis cold nature, salty in the mouth have effects such as promoting blood circulation to restore menstrual flow, detumescence, crux mass in the abdomen, carbuncle.Eupolyphaga Seu Steleophaga also claims
Worm is the adult dry body of Corydiidae insecticide, and cold nature, bitter in the mouth are poisonous, energy inducing menstruation to relieve menalgia, removing blood stasis, removing food stagnancy, the long-pending lump of the stasis of blood.Radix Curcumae is cold in nature, bitter in the mouth is hot, energy circulation of qi promoting, resolving depression, removing heat from blood removing blood stasis with potent drugs etc.Aspongopus is warm in nature, the sweet in the mouth suffering, and the energy regulating QI to relieve pain, the warming middle-JIAO tonifying YANG is every the stagnant gas of institute.Zaocys sweet-salty, flat, energy wind-damp dispelling, the meridian dredging.
Used Scolopendra, Squama Manis, Eupolyphaga Seu Steleophaga, Zaocys, the Aspongopus of the present invention is dry polypide.
Described antitumor, cancer therapy drug are the above dosage forms of any pharmaceutics.
The medicament of described antitumor, cancer therapy drug is powder or piece agent.
The present invention makes by following existing processing method: it is qualified by above-mentioned prescription crude drug to be concocted, and weighing is assorted, and mixes and is ground into fine powder, incapsulate or suppress in flakes or make pill, electuary gets final product.Each 1-3 gram for oral administration, one day 2-3 time.
The present invention has following advantage and effect: the present invention's medicine adopts the pure natural Chinese herbal medicine to make, and has heat-clearing and toxic substances removing, and blood circulation promoting and blood stasis dispelling removes the disease eliminating stagnation, the warming the meridian removing food stagnancy is set upright tonify deficiency, hemostasia and detumescence, inducing menstruation to relieve menalgia, multiple efficacies such as circulation of qi promoting removing heat from blood can effectively be treated lymphatic cancer, breast carcinoma, nose, laryngeal carcinoma and pulmonary carcinoma, hepatocarcinoma, cancers such as stomach, intestinal cancer, cure rate is higher, reaches more than 75% taking convenience, having no side effect, can also improve body resistivity and immunity, is an ideal curing cancer drug in fact.
For showing curative effect of the present invention, now of the present invention 90 routine clinical observation result are reported as follows:
One, data and method
1, physical data
Cancer patient's 90 examples of making a definite diagnosis through local hospital, wherein, lymphatic cancer patient 15 examples, manifest symptom are that lump is arranged, and enlargement day by day, pain is obvious; Patient with breast cancer's 20 examples, manifest symptom is a distending pain of the breast, and lump is arranged, and can not sleep peacefully; Patients with lung cancer 15 examples, manifest symptom is a dyspnea, cough band blood, the feed difficulty, sleep reduces; Liver cancer patient 20 examples, with the abdominal part enlargement, pain unbearably, appetite is few, sleep is few; Stomach, intestinal cancer patient's 20 examples, manifest symptom are that stomachache is hard to bear, can not take food difficulty in walking.Now with all kinds of case random packet, details see Table 1.
Two groups of patients' ordinary circumstance (n=90) is organized in table 1 matched group and treatment
| Project | Lymphatic cancer treatment group (n=8) | (n=15 matched group (n=7) | Breast cancer treatment group (n=10) | (n=20) matched group (n=10) | Pulmonary carcinoma liver cancer treatment group (n=13) | (n=35) matched group (n=12) | Gastric cancer intestinal cancer treatment group (n=10) | (n=20) contrast fine horse (n=10) |
| Sex masculinity femininity age 26-35 year 31-50 year is more than 51 years old | 3 5 2 4 2 | 3 4 1 4 2 | 10 3 4 3 | 10 2 4 4 | 9 4 2 5 6 | 7 5 3 4 5 | 5 5 2 5 3 | 4 6 2 5 3 |
Through X
2Check, two groups of ages, sex, characteristic of diseases all have comparability (p＞0.05)
2, Therapeutic Method
Matched group is taken commercially available anticancer tablet, three times on the one.
The treatment group is taken the present invention's capsule, and three times on the one, each 2.0g uses warm water delivery service.
All take by the identical course of treatment for two groups, 3-6 month is a course of treatment, obeys three courses of treatment altogether, be the state of an illness control phase first course of treatment, be that cancerous cell kills and wounds and the toxin expelling phase second course of treatment, and be the phase of consolidating and strengthening the 3rd course of treatment, and cut out other related drugs during treating.
3, observational technique
Period in a medicine is regularly observed, and comprises symptom, sign improvement situation, untoward reaction.The pressure of having a blood test respectively before and after the treatment is looked into heart, liver, renal function and routine urinalysis.Treatment finishes to check the state of an illness to hospital in two weeks.
Two, curative effect judgment criteria
1, criterion of therapeutical effect
According to Ministry of Public Health bureau of drug administration about the clinical research guideline of cancer " new drug (Chinese medicine) treatment ", criterion of therapeutical effect.
Cure: cancerous cell reduces, and body immunity improves, and resistance strengthens, and is energetic, painless;
Produce effects: cancerous cell is effectively controlled, and immunity increases, no pain;
Effectively: cancerous cell is inhibited substantially, and immunity improves, and spirit is not good enough, pain relief;
Invalid: cancerous cell is constant, and inflammation is not eliminated, and mental status is poor, still has pain, and symptom is obvious.
2, statistical method
Enumeration data adopts X
2The t check is adopted in check, measurement data.
Total effective rate=cure rate+obvious effective rate+effective percentage
Three, result
1, lymphatic cancer improvement situation sees Table 2.
Table 2, lymphatic cancer improve situation (15 example)
| Cure | Produce effects | Effectively | Invalid | Effective percentage | |
| 8 matched groups 7 are organized in treatment | 1 | 2 1 | 3 3 | 2 3 | 75.00％ 57.12％ |
Treatment group curative effect obviously is better than matched group (p＞0.01)
2, breast carcinoma improvement situation sees Table 3.
Table 3, breast carcinoma are improved situation (20 example)
| Cure | Produce effects | Effectively | Invalid | Effective percentage | |
| 10 matched groups 10 are organized in treatment | 2 1 | 2 1 | 4 4 | 2 4 | 80.00％ 60.00％ |
Treatment group curative effect obviously is better than matched group (p＞0.01)
3, hepatocarcinoma, pulmonary carcinoma improvement situation see Table 4.
Table 4, hepatocarcinoma, pulmonary carcinoma are improved situation (35 example)
| Cure | Produce effects | Effectively | Invalid | Effective percentage | |
| 13 matched groups 12 are organized in treatment | 2 1 | 3 2 | 5 3 | 3 6 | 76.92％ 50.00％ |
Treatment group curative effect obviously is better than matched group (p＞0.01)
4, gastric cancer, intestinal cancer improvement situation see Table 5.
Table 5, gastric cancer, intestinal cancer are improved situation (20 example)
| Cure | Produce effects | Effectively | Invalid | Effective percentage | |
| 10 matched groups 10 are organized in treatment | 2 1 | 3 2 | 3 3 | 2 4 | 80.00％ 60.00％ |
Treatment group curative effect obviously is better than matched group (p＞0.01)
5, untoward reaction
Treatment group patient has no adverse reaction.The matched group patient has symptom in various degree such as xerostomia, scorching, constipation.
Four, discuss
The present invention is the pure natural Chinese herbal and crude drugs preparations, it is through research and the clinical observation of two more than ten years, in conjunction with the Chinese medicine theory, comparatively complicated at the tumor invasion cause of disease, and features such as individual variation is bigger, from heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, remove disease eliminating stagnation, treating the poisonous disease with poisonous drugs, warming the meridian removing food stagnancy, set upright many aspects such as tonify deficiency and adjust treatment, cooperate postoperative treatment more favourable again, this medicine particularly takes effect to the patient that cancerous cell does not spread as yet, total effective rate reaches more than 75%, has obtained excellent curative.
But in view of the clinical trial of the present invention's medicine under without any foreign aid's condition and be that private clinic is finished, all patients take medicine home conscious the taking medicine in back and treat, there are not treatment, rehabilitation supervision mechanism, to can not adhering on time, take medicine according to quantity that it is irregular to live, comparatively frightened, pessimistic to self cancer, the spirit hypertonicity, and disorderly seek medical advice, abuse the patient of medicine, its effect is unconspicuous.In addition to sb.'s illness took a turn for the worse, the patient with advanced cancer that cancerous cell has spread is because of missing best medication period, so effect is also not obvious.
In addition, because the present invention's medicine has decomposition, neutralization, the function of removing food stagnancy and change cancerous cell and toxin, the fierce motion of cell generation be can make after taking medicine and a large amount of moisture content and nutrient consumed, therefore, during treating, the patient is xerostomia sometimes, just rare not obvious, for this reason, the patient who receives treatment should not restrain appetite, answer polydipsia water, eat fruit more, vegetable is strengthened nutrition, and then lump dwindles, transference cure is very fast, body immunity and resistance are easy to recover, the period in a medicine nerve, thinking and condition etc. are not subjected to the influence of medicine, oppose the damage that some health flesh of tumor patient can be subjected to mutually, also have certain healing effect.
The specific embodiment
Below in conjunction with embodiment the present invention is described further.
Embodiment 1
Get material by following prescription:
100 parts of 300 parts of Scolopendras of Radix Notoginseng
600 parts of 400 parts of Squama Maniss of Semen Caesalpiniae Minacis
500 parts of 300 parts of Zaocys of Eupolyphaga Seu Steleophaga
300 parts of 500 portions of Aspongopuss of Radix Curcumae
Make through following method: it is qualified by above-mentioned prescription crude drug to be concocted, and weighing is assorted, and mixes and is ground into fine powder, and the softgel shell of packing into promptly gets the present invention's capsule.
Embodiment 2
Get material by following prescription:
50 parts of 700 parts of Scolopendras of Radix Notoginseng
300 parts of 600 parts of Squama Maniss of Semen Caesalpiniae Minacis
400 parts of 600 parts of Zaocys of Eupolyphaga Seu Steleophaga
200 parts of 700 portions of Aspongopuss of Radix Curcumae
Make through following method: it is qualified by above-mentioned prescription crude drug to be concocted, and weighing is assorted, and mixes and is ground into fine powder, and compacting getting final product in flakes.
Embodiment 3
Get material by following prescription:
60 parts of 400 parts of Scolopendras of Radix Notoginseng
400 parts of 500 parts of Squama Maniss of Semen Caesalpiniae Minacis
300 parts of 400 parts of Zaocys of Eupolyphaga Seu Steleophaga
200 parts of 500 portions of Aspongopuss of Radix Curcumae
Make through following method: it is qualified by above-mentioned prescription crude drug to be concocted, and weighing is assorted, and mixes and is ground into fine powder, makes pill and gets final product.
Embodiment 4
Get material by following prescription:
80 parts of 600 parts of Scolopendras of Radix Notoginseng
600 parts of 600 parts of Squama Maniss of Semen Caesalpiniae Minacis
500 parts of 600 parts of Zaocys of Eupolyphaga Seu Steleophaga
300 parts of 600 portions of Aspongopuss of Radix Curcumae
Make through following method: it is qualified by above-mentioned prescription crude drug to be concocted, and weighing is assorted, and mixes and is ground into fine powder, makes electuary and gets final product.
Embodiment 5
Get material by following prescription, and make capsule with the method for embodiment 1:
70 parts of 500 parts of Scolopendras of Radix Notoginseng
500 parts of 500 parts of Squama Maniss of Semen Caesalpiniae Minacis
500 parts of 500 parts of Zaocys of Eupolyphaga Seu Steleophaga
200 parts of 600 portions of Aspongopuss of Radix Curcumae.
Claims (6)
1, a kind of antitumor, cancer therapy drug is characterized in that it is the medicament of being made by following quality proportion raw material:
Radix Notoginseng 300-700 part Scolopendra 50-100 part
Semen Caesalpiniae Minacis 400-600 part Squama Manis 300-600 part
Eupolyphaga Seu Steleophaga 300-600 part Zaocys 400-500 part
Radix Curcumae 500-700 part Aspongopus 200-300 part.
2, antitumor according to claim 1, cancer therapy drug is characterized in that the weight proportion of each raw material is:
Radix Notoginseng 400-600 part Scolopendra 60-80 part
Semen Caesalpiniae Minacis 500-600 part Squama Manis 400-600 part
Eupolyphaga Seu Steleophaga 400-600 part Zaocys 300-500 part
Radix Curcumae 500-600 part Aspongopus 200-300 part.
3, antitumor according to claim 1, cancer therapy drug is characterized in that the weight proportion of each raw material is:
70 parts of 500 parts of Scolopendras of Radix Notoginseng
500 parts of 500 parts of Squama Maniss of Semen Caesalpiniae Minacis
500 parts of 500 parts of Zaocys of Eupolyphaga Seu Steleophaga
200 parts of 600 portions of Aspongopuss of Radix Curcumae.
4, antitumor according to claim 1, cancer therapy drug is characterized in that described Scolopendra, Squama Manis, Eupolyphaga Seu Steleophaga, Zaocys, Aspongopus are dry polypide.
5, antitumor according to claim 1, cancer therapy drug is characterized in that described antitumor, cancer therapy drug are the above dosage forms of any pharmaceutics.
6, antitumor according to claim 1, cancer therapy drug, the medicament that it is characterized in that described antitumor, cancer therapy drug are powder or piece agent.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2007100656561A CN100531791C (en) | 2007-02-06 | 2007-02-06 | Antineoplastic, anti-cancer drugs |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2007100656561A CN100531791C (en) | 2007-02-06 | 2007-02-06 | Antineoplastic, anti-cancer drugs |
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| Publication Number | Publication Date |
|---|---|
| CN101011558A true CN101011558A (en) | 2007-08-08 |
| CN100531791C CN100531791C (en) | 2009-08-26 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2007100656561A Expired - Fee Related CN100531791C (en) | 2007-02-06 | 2007-02-06 | Antineoplastic, anti-cancer drugs |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103565985A (en) * | 2013-11-06 | 2014-02-12 | 陈兴日 | Traditional Chinese medicinal composition for treating breast pain and using method thereof |
| CN104352790A (en) * | 2014-11-17 | 2015-02-18 | 刘岚 | Medicine for postoperative recovery of breast cancer and preparation method of medicine |
| CN105902669A (en) * | 2016-04-29 | 2016-08-31 | 张萌 | Compound preparation promoting tumor compression post-operation healing |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1288748A (en) * | 1999-09-17 | 2001-03-28 | 郅永谦 | Medicine for treating cardiac and cerebral vascular diseases and its preparation |
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2007
- 2007-02-06 CN CNB2007100656561A patent/CN100531791C/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103565985A (en) * | 2013-11-06 | 2014-02-12 | 陈兴日 | Traditional Chinese medicinal composition for treating breast pain and using method thereof |
| CN104352790A (en) * | 2014-11-17 | 2015-02-18 | 刘岚 | Medicine for postoperative recovery of breast cancer and preparation method of medicine |
| CN105902669A (en) * | 2016-04-29 | 2016-08-31 | 张萌 | Compound preparation promoting tumor compression post-operation healing |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100531791C (en) | 2009-08-26 |
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Granted publication date: 20090826 Termination date: 20160206 |