CN101011060A - Pesticide composition comprising highly effective cypermethrin and hexaflumuron - Google Patents

Abstract

The present invention relates to a kind of pesticide composition, more specifically relate to a kind of pesticide composition comprising effective amount of beta-cypermethrin and hexaflumuron, wherein the weight ratio of beta-cypermethrin and hexaflumuron is preferably 1:1～9 :1, more preferably 7:3 to 8:2. The pesticide composition is particularly suitable for controlling sanitary pests such as houseflies and cockroaches.

Description

Pesticide composition containing beta-cypermethrin and hexaflumuron

technical field

The invention relates to a synergistic pesticide composition, in particular to a synergistic pesticide composition comprising beta-cypermethrin and hexaflumuron.

Background technique

Alphamethrin is a high-efficiency, broad-spectrum pyrethroid insecticide. The drug is a nerve axon conduction inhibitor, which belongs to the nerve agent and has a rapid action. It has good control effects on various pests on wheat, cotton, vegetables, fruits, soybeans and other crops, and has an ovicidal effect on some pests. . Beta-cypermethrin has a simple synthesis process and low cost, so it is widely used in the control of agricultural pests. However, beta-cypermethrin also has a very obvious shortcoming, that is, the duration of efficacy is relatively short. In practical applications, due to the high frequency of application, pest resistance is generated and the efficacy of the drug decreases.

Hexafluron is a new type of benzoylurea insecticide, its main mechanism of action is to inhibit the synthesis of chitin, hinder the normal molt and metamorphosis of insects. The drug has high larvicidal and ovicidal activity, has a sterile effect on adults, and hinders the development of eggs. The drug mainly has stomach poisoning effect, and also has contact killing effect, strong knockdown force and rapid action. It is mainly used to control Lepidoptera, Coleoptera, Homoptera and Diptera pests on cotton, vegetables, fruit trees and other crops.

After a lot of research, the applicant found that the mixed use of beta-cypermethrin and hexaflumuron has an unexpected control effect on the control of sanitary pests such as houseflies and cockroaches, and its synergistic effect is very obvious. Moreover, the mixed use of the two has the characteristics of high efficiency, good quick-acting effect, long-lasting effect, delayed drug resistance, and environmental safety for the control of houseflies and cockroaches and other sanitary pests, so it is a very good sanitary pest control agent. In addition, the applicant found through searching that there are no detailed reports on the mixing of beta-cypermethrin and hexaflumuron to prevent and control sanitary pests at home and abroad. Polyester is used to prevent and control fish parasites, but because it is not the same as the active ingredient, control object, mixing ratio, etc. of the pesticide composition used in the present application, and it does not provide any synergistic test data for mixing. Based on the above findings, the applicant has completed the present invention.

Contents of the invention

The purpose of the present invention is to provide a synergistic pesticide composition with reasonable mixing ratio, good control effect and low medication cost.

Another object of the present invention is to provide formulations such as emulsifiable concentrate, microemulsion, wettable powder, water dispersible granule prepared from the pesticide composition.

Another object of the present invention is to provide the use of the pesticide composition for controlling houseflies and cockroaches.

Technical scheme of the present invention is as follows:

A pesticide composition is characterized in that it contains effective synergistic amounts of beta-cyanochloride and hexaflumuron.

The weight ratio of high-efficacy cyanochloride to hexaflumuron is preferably 1:1-9:1, more preferably 7:3-8:2. The pesticide composition of the present invention can be formulated into dosage forms such as emulsifiable concentrate, microemulsion, wettable powder, water dispersible granule according to methods known to those skilled in the art.

The auxiliaries available in the preparation of emulsifiable concentrates are:

Solvents and co-solvents include aromatic hydrocarbons, aliphatic hydrocarbons, ethers, phenols, alcohols, etc., such as benzene, petroleum ether, methanol, xylene, ethanol, n-butanol, toluene, isoamyl alcohol, ethyl acetate, chloroform , kerosene, dimethyl sulfoxide, phenol, engine oil, etc. Wherein the content of solvent and auxiliary solvent generally accounts for 15-90wt%.

Emulsifiers include fatty alcohol polyoxyethylene ether, alkylphenol polyoxyethylene ether, styrylphenol polyoxyethylene ether, alkylphenol polyoxyethylene ether sulfosuccinate, castor oil polyoxyethylene ether, fatty acid polyoxyethylene ether Oxyalkylene esters, alkylaryl sulfonates, etc., such as 2201, Nongru 0203B, 0201B, 6202B, Nongru OX-2568, 500#, 600#, 700#, 6201, 602, 790, 1602, 1303, 603 etc. One or more emulsifiers can be mixed, and the general usage is 10-20wt%.

The pH regulator includes sodium hydroxide, potassium hydroxide, hydrochloric acid, acetic acid, etc., and the general dosage is 0.5-1wt%.

Auxiliaries that can be used in the preparation of microemulsions are:

Emulsifiers include alkylbenzene sulfonate series, diphenylphenol polyoxyethylene polyoxypropylene ether, polyoxyethylene distyrene methyl phenyl ether, styrene phenol polyoxyethylene ether, polyoxyethylene styrene Phenolic ether, alkylphenol polyoxyethylene ether formaldehyde condensate, diphenylphenol polyoxyethylene ether formaldehyde condensate, castor oil ethylene oxide adduct and its derivatives, etc., such as Nongru 300#, 700 #, OX-2511, Nongru 2201, Nongru 500, Nongru Sorpl KS, Ningru 130, NP series, etc. The emulsifier can be one or more mixed, and the general usage is 10-30wt%.

Solvents and co-solvents include aromatic hydrocarbons, alcohols, esters, ketones, amides, such as methanol, ethanol, butanol, acetone, toluene, xylene, dimethylformamide, cyclohexanone, dimethylmethylene Sulfone, pyrrolidone, C _3-6 ketone, etc., can be a mixture of one or more, and the general dosage accounts for 20-60wt%

Antifreeze agents include glycerin, propylene glycol, ethylene glycol, sodium chloride, urea, glycerol, sorbitol, etc., generally in an amount of 1-8 wt%.

Stabilizers include urea, methanol, petroleum ether, wettable starch, cresyl glycidyl alcohol, etc., generally used in an amount of 0.5-10 wt%.

The defoaming agent includes silicone oil, methanol, ethanol, epoxy soybean oil, etc., and the general dosage is 0.5-8wt%.

Auxiliaries that can be used in the preparation of wettable powders are:

Carriers (fillers) include kaolin, activated clay, diatomaceous earth, peat, light calcium carbonate, white carbon black, pyrophyllite, talc, calcite, etc. It can be a mixture of one or more, and the general dosage is 15-75wt%

Dispersants include anionic dispersants, sulfurous acid refers to waste liquid, sodium lignosulfonate, calcium lignosulfonate, nonionic surfactants such as polyoxyethylene polyoxypropylene ether block copolymer, alkylphenol poly Oxyethylene phosphate etc. It can be a mixture of one or more, and the general dosage is 5-35wt%.

Wetting agents include natural products and anionic surfactants such as tea dry powder, saponin powder, SOPA (230, 270, 235), washing powder, sodium dodecylbenzene sulfonate, pull open powder, Nongru No. 2000 series, wetting and penetrating agent F, etc. It can be a mixture of one or more, and the general dosage is 5-30wt%.

Other stabilizers and defoamers are equivalent to microemulsions.

The auxiliaries available in the preparation of water dispersible granules are:

The wetting agent can be sodium alkylbenzene sulfonate, sodium lignin sulfonate, fatty alcohol, alkyl sulfate, alkylphenol polyoxyethylene ether, sulfurous acid pulp waste liquid, tea dry powder, saponin powder, etc. It can be a mixture of one or more, and the general dosage is 5-30wt%.

The dispersant can be polyoxyethylene lauryl ether, sodium naphthalene sulfonate formaldehyde condensate (N N O ), sodium dioctyl sulfosuccinate, sodium acrylic acid homopolymer, JFC, etc. It can be a mixture of one or more, and the general dosage is 5-10wt%.

Carriers include white kaolin, light calcium carbonate, white carbon black, montmorillonite, diatomaceous earth, rice husk, etc. It can be a mixture of one or more, and the general dosage is 15-70wt%.

Binders include soybean lecithin, gelatin, polyvinyl alcohol, polyethylene glycol, cyclohexidine, rosin, starch and the like. It can be one or more mixtures, and the general usage is 1-10wt%.

Disintegrants include bentonite, ammonium sulfate, urea, magnesium chloride, sodium chloride, etc. It can be a mixture of one or more, and the general dosage is 5-15wt%.

Detailed ways:

The present invention will be further described below in conjunction with embodiment, but the present invention is by no means limited to following embodiment. Preparation Example 1: The weight ratio of each component of emulsifiable concentrate

Beta-Cypermethrin 8%

Buflufluramide 2%

500# 10%

Toluene Fill up to 100%

Formulation example 2: the weight proportion of each component of microemulsion

Cypermethrin 3.5%

Hexaflumuron 0.5%

Glycerin 5%

Sodium lignosulfonate 20%

Farm Milk 0203B 10%

Make up to 100% with deionized water

Formulation example 3: the weight ratio of each component in the wettable powder

Beta-cypermethrin 4.5%

Hexaflumuron 2.5%

Sodium dodecylbenzenesulfonate 20%

Calcium lignosulfonate 15%

Activated clay fill up to 100%

Biological Example 1: The co-toxicity coefficient measurement results of the mixed use of high-efficiency cyanochloropolyester and hexaflumuron to houseflies and cockroaches

Table 1 Toxicity of beta-cypermethrin and hexaflumuron mixed to housefly

Drug (weight ratio) Y=a+bx r LC ₅₀ μg/ml 95% confidence limit μg/ml Co-toxicity coefficient Beta-cypermethrin Y=2.7782+1.2737x 0.9923 55.1 38.9～78.0 - Hexaflumuron Y=1.8341+1.4726x 0.9812 137.6 104.0～182.2 - Beta-cypermethrin: hexaflumuron (1:1) Y=2.5429+1.3674x 0.9868 62.3 45.6～85.0 126 Beta-cypermethrin: hexaflumuron (3:2) Y=3.0670+1.3082x 0.9727 32.0 22.7～45.3 227 Beta-cypermethrin: hexaflumuron (7:3) Y=2.6002+1.7517x 0.9779 23.5 18.3～30.2 286 Beta-cypermethrin: hexaflumuron (8:2) Y=3.7826+0.9898x 0.9880 22.2 14.0～35.2 282 Beta-cypermethrin: hexaflumuron (9:1) Y=3.1635+1.3397x 0.9676 24.6 17.8～34.1 238

Table 2 Toxicity of beta-cypermethrin and hexaflumuron mixed to cockroaches

Drug (weight ratio) Y=a+bx r LC ₅₀ μg/ml 95% confidence limit μg/ml Co-toxicity coefficient Beta-cypermethrin Y=1.3654+1.5664x 0.9882 208.3 160.5～270.3 - Hexaflumuron Y=1.2189+1.2816x 0.9696 861.2 616.6～1202.9 - Beta-cypermethrin: hexaflumuron (1:1) Y＝0.1416+2.0681x 0.9508 219.9 177.0～273.1 153 Beta-cypermethrin: hexaflumuron (3:2) Y=2.7928+0.9830x 0.9651 176.8 116.4～268.6 169 Beta-cypermethrin: hexaflumuron (7:3) Y=1.7513+1.5038x 0.9799 142.5 106.9～190.1 189 Beta-cypermethrin: hexaflumuron (8:2) Y=2.2430+1.3014x 0.9553 128.3 92.63～177.7 192 Beta-cypermethrin: hexaflumuron (9:1) Y=1.8806+1.4926x 0.9546 120.7 90.49～161.1 187

Biological Example 2: The efficacy test results of beta-cypermethrin and hexaflumuron mixture

Dilute 5% high chlorine and fluorine suspension concentrate, 10% high chlorine and fluorine emulsifiable concentrate and 7% high chlorine and fluorine wettable powder respectively 400, 800 and 1200 times to spray the housefly, and investigate the control effect 12 and 48 hours after the application , the result is as follows:

5% high chlorine · fluorine suspension diluted 400, 800, 1200 times, the 12-hour control effects were 93%, 76%, 65%; 48-hour control effects were 97%, 95%, 90%.

10% high chlorine · fluorine EC diluted 400, 800, 1200 times, the 12-hour control effects were 98%, 82%, 67%; 48-hour control effects were 96%, 94%, 92%.

7% high chlorine · fluorine wettable powder diluted 400, 800, 1200 times, the 12-hour control effects were 92%, 74%, 63%; 48-hour control effects were 95%, 90%, 87%.

Claims (5)

1. composition pesticide is characterized in that containing the beta-cypermethrin and the fluorine bell urea of synergy effective dose.

2. according to the composition pesticide of claim 1, it is characterized in that the weight ratio of beta-cypermethrin and fluorine bell urea is 1: 1～9: 1.

3. according to the composition pesticide of claim 2, it is characterized in that the weight ratio of beta-cypermethrin and fluorine bell urea is 7: 3～8: 2.

4. according to the described composition pesticide of arbitrary claim formulated missible oil, microemulsion, wetting powder or the water dispersible granules of claim 1 to 3.

5. the purposes that the described composition pesticide of arbitrary claim of claim 1 to 3 is used for anti-housefly and blattaria.