CN100574773C - The endo-medicine of a kind of therapy of combining Chinese and Western medicine Ctenopharyngodon idellus " bacterial gill rot disease " - Google Patents
The endo-medicine of a kind of therapy of combining Chinese and Western medicine Ctenopharyngodon idellus " bacterial gill rot disease " Download PDFInfo
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- CN100574773C CN100574773C CN200610043276A CN200610043276A CN100574773C CN 100574773 C CN100574773 C CN 100574773C CN 200610043276 A CN200610043276 A CN 200610043276A CN 200610043276 A CN200610043276 A CN 200610043276A CN 100574773 C CN100574773 C CN 100574773C
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Abstract
The invention discloses the endo-medicine of a kind of therapy of combining Chinese and Western medicine Ctenopharyngodon idellus " bacterial gill rot disease ", it is formulated by: Enrofloxacin HCL, trimethoprim, the Radix Astragali.The present invention can be by antimicrobial drug and synergist associating compatibility, to improve the antibacterial action and the prophylactic treatment effect of medicine, compatibility has the prevention of imitating and treats the generation of this disease, compatibility has the Chinese herbal medicine of immunization, purpose is the non-specific immunity that effectively strengthens Ctenopharyngodon idellus, to improve the result of use of medicine.Drug therapy Ctenopharyngodon idellus of the present invention " bacterial gill rot disease " cure rate can reach more than 80%.
Description
Affiliated technical field
The present invention relates to fish disease prevention and cure medicine in a kind of aquaculture, especially treat the endo-medicine of Ctenopharyngodon idellus " bacterial gill rot disease ".
Background technology
Ctenopharyngodon idellus " bacterial gill rot disease " is the disease that is caused by bacterial infection.Though the aquatic science worker has done a large amount of scientific researches and production practices work to Ctenopharyngodon idellus " bacterial gill rot disease ", it is still the important diseases of present puzzlement Ctenopharyngodon idellus aquaculture.In the Ctenopharyngodon idellus breeding production, the sickness rate of Ctenopharyngodon idellus " bacterial gill rot disease " is the highest, dead quantity maximum, and cure rate is lower, and the culturing economic loss that causes thus is also bigger.Therefore, we had done a large amount of experiments and work to this in the last few years, had summed up the technological package measure of prevention and treatment Ctenopharyngodon idellus " bacterial gill rot disease ", and had optimized the specially good effect endo-medicine of a kind of therapy of combining Chinese and Western medicine Ctenopharyngodon idellus " bacterial gill rot disease ".Production practices in recent years prove that this endo-medicine reaches more than 90% the cure rate of Ctenopharyngodon idellus " bacterial gill rot disease ".
Summary of the invention
We selected for use the 3rd generation synthetic quinolone antimicrobial, synergist and Chinese herbal medicine with immunization carry out prescription, and be applied to the screening that breeding production is carried out endo-medicine, be intended to optimize best and endo-medicine specific prevention and treatment Ctenopharyngodon idellus " three diseases ".Composition principle: antimicrobial drug and synergist associating compatibility, with the antibacterial action that improves medicine and prevention, therapeutic effect: compatibility has the Chinese herbal medicine of immunization, its effect is the non-specific immunity that effectively strengthens Ctenopharyngodon idellus, improves its premunition, to promote the result of use of medicine.
The object of the present invention is achieved like this
By screening, the ingredient in prevention and treatment Ctenopharyngodon idellus " bacterial gill rot disease " the endo-medicine prescription has following three kinds:
1. Enrofloxacin HCL: its chemistry is by name: 1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-7-(4-ethyl-1-piperazinyl)-3-quinoline carboxylic acid, crystalline powder for little yellow and faint yellow, odorless, mildly bitter flavor, belong to synthetic quinolones broad spectrum antibiotic of the 3rd generation, the DNA gyrase that can effectively suppress antibacterial, blocking-up duplicating of DNA of bacteria and produce the quick sterilization effect.Therefore, Gram-positive, negative bacterium and each mycoplasma species etc. all there are very strong killing action, splendid to the curative effect of mycoplasma and various bacteria mixed infection.And its sterilizing power is strong, absorbs soon, and it is wide to distribute, and untoward reaction is few, and does not have cross resistance between other antimicrobial agents, not influenced by plasmid conduction drug resistance.
2, trimethoprim: have another name called trimethoxy diamino, trimethoprim (TMP), trimethoprim, its chemistry is by name: 2,4 diaminourea-5-(3,4,5-trimethoxy benzyl) pyrimidine is white or off-white color crystalline powder.Its antimicrobial spectrum is similar substantially with sulphonamides, but antibacterial action is stronger, and its basic antibacterial action mechanism is to suppress the antibacterial dihydrofolate reductase, thereby stops the synthetic of bacterial nucleic acid.Use separately, the very easy generation drug resistance of antibacterial, effective to multiple Grain-positive and negative bacteria.But during with the sulphonamides use in conjunction, can make the folic acid metabolism of antibacterial suffer double blocking, the antibacterial action that strengthens sulfanilamide reaches several times to tens times, experiment showed, that TMP and Enrofloxacin HCL compatibility use, and its antibacterial action and curative effect all obviously strengthen.
3, the Radix Astragali: have another name called hundred, hundred absorbent cotton etc., it is a kind of Chinese herbal medicine, its powder is a yellow-white, it not only has the promotion organism metabolism, antibiotic and suppress virus, enhanced virus inducement interferon, body hypoxia-bearing and stress ability, improve cardiac function, blood sugar regulation, blood pressure lowering, effect such as protect the liver, and can strengthen the fish body immunity function, improve premunition, promptly, blood leukocytes and multinuclear leucocyte quantity are significantly increased by strengthening the phagocytic function of reticuloendothelial system, macrophage phagocytic percentage rate index significantly rises, thereby humoral immunization is all had facilitation.
Prescription is formed: the former powder 30-50 of Enrofloxacin HCL milligram, the former powder 6-10 of trimethoprim milligram, astragalus membranaceus powder 1.5-2 kilogram, other adds flour 2.5-3 kilogram.
Using method;
Said medicine is added in the double centner feed of grass carp, threw something and fed continuously 5-7 days, use and treat Ctenopharyngodon idellus " bacterial gill rot disease ", during prevention, the addition of medicine reduces by half.Simultaneously even water disinfectant such as float chlorine dioxide in the breeding water body to improve water quality, is beneficial to the prevention and the treatment of Ctenopharyngodon idellus " bacterial gill rot disease ".
Claims (1)
1. the endo-medicine of a therapy of combining Chinese and Western medicine Ctenopharyngodon idellus " bacterial gill rot disease ", it is characterized in that forming by the following weight ratio component, the former powder 30-50 of Enrofloxacin HCL milligram, the former powder 6-10 of trimethoprim milligram, astragalus membranaceus powder 1.5-2 kilogram, other adds flour 2.5-3 kilogram, above-mentioned component is gone packing again after mixing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200610043276A CN100574773C (en) | 2006-03-27 | 2006-03-27 | The endo-medicine of a kind of therapy of combining Chinese and Western medicine Ctenopharyngodon idellus " bacterial gill rot disease " |
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| Application Number | Priority Date | Filing Date | Title |
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| CN200610043276A CN100574773C (en) | 2006-03-27 | 2006-03-27 | The endo-medicine of a kind of therapy of combining Chinese and Western medicine Ctenopharyngodon idellus " bacterial gill rot disease " |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101045078A CN101045078A (en) | 2007-10-03 |
| CN100574773C true CN100574773C (en) | 2009-12-30 |
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| CN200610043276A Expired - Fee Related CN100574773C (en) | 2006-03-27 | 2006-03-27 | The endo-medicine of a kind of therapy of combining Chinese and Western medicine Ctenopharyngodon idellus " bacterial gill rot disease " |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102144967B (en) * | 2010-04-23 | 2012-06-06 | 镇江威特药业有限责任公司 | Veterinary long-acting compound doxycycline injection and preparation method thereof |
| CN103251753B (en) * | 2013-06-08 | 2014-07-02 | 潘李亮 | Traditional Chinese medicine composition for treating streptococcicosis of tilapia mossambica |
| CN104800162A (en) * | 2014-01-26 | 2015-07-29 | 天津嘉创生物科技有限公司 | Splashing medicinal composition for treating fish branchiomycosis, and preparation method thereof |
| CN105327319A (en) * | 2015-11-27 | 2016-02-17 | 青岛海之源智能技术有限公司 | Tincture for treating bacterial gill-rot disease of channel catfish and preparation method thereof |
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2006
- 2006-03-27 CN CN200610043276A patent/CN100574773C/en not_active Expired - Fee Related
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Granted publication date: 20091230 Termination date: 20100327 |