CN100566719C - 用于治疗尤其是在糖尿病患者中的肾的功能障碍、疾病或者病症的药物组合物 - Google Patents

用于治疗尤其是在糖尿病患者中的肾的功能障碍、疾病或者病症的药物组合物 Download PDF

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Publication number
CN100566719C
CN100566719C CNB2004800330307A CN200480033030A CN100566719C CN 100566719 C CN100566719 C CN 100566719C CN B2004800330307 A CNB2004800330307 A CN B2004800330307A CN 200480033030 A CN200480033030 A CN 200480033030A CN 100566719 C CN100566719 C CN 100566719C
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China
Prior art keywords
treatment
group
patients
formula
alkyl
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CNB2004800330307A
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English (en)
Chinese (zh)
Other versions
CN1878557A (zh
Inventor
D·托尔梅伦
B·赫歇尔
H·瓦尔德克
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Abbott Products GmbH
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Solvay Pharmaceuticals GmbH
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Publication of CN1878557A publication Critical patent/CN1878557A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CNB2004800330307A 2003-11-18 2004-11-15 用于治疗尤其是在糖尿病患者中的肾的功能障碍、疾病或者病症的药物组合物 Expired - Fee Related CN100566719C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03104264.1 2003-11-18
EP03104264 2003-11-18

Publications (2)

Publication Number Publication Date
CN1878557A CN1878557A (zh) 2006-12-13
CN100566719C true CN100566719C (zh) 2009-12-09

Family

ID=34610099

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB2004800330307A Expired - Fee Related CN100566719C (zh) 2003-11-18 2004-11-15 用于治疗尤其是在糖尿病患者中的肾的功能障碍、疾病或者病症的药物组合物

Country Status (15)

Country Link
US (1) US7273860B2 (https=)
EP (1) EP1687006B1 (https=)
JP (1) JP4824573B2 (https=)
CN (1) CN100566719C (https=)
AR (1) AR046454A1 (https=)
AT (1) ATE378053T1 (https=)
AU (1) AU2004290925B2 (https=)
BR (1) BRPI0416706A (https=)
CA (1) CA2545802A1 (https=)
DE (1) DE602004010172T2 (https=)
ES (1) ES2297536T3 (https=)
MX (1) MXPA06005547A (https=)
PL (1) PL1687006T3 (https=)
TW (1) TWI344366B (https=)
WO (1) WO2005049035A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60040089D1 (de) * 1999-11-19 2008-10-09 Solvay Pharm Bv Menschliches homolog aus der familie der metalloproteasen
AR049401A1 (es) 2004-06-18 2006-07-26 Novartis Ag Aza-biciclononanos
GB0415746D0 (en) 2004-07-14 2004-08-18 Novartis Ag Organic compounds
US20060159748A1 (en) * 2004-12-23 2006-07-20 Rajesh Jain Oral immediate release formulation of a poorly water-soluble active substance
TWI741240B (zh) * 2017-12-11 2021-10-01 日商埃塔斯製藥股份有限公司 含有1,4-苯并硫氮呯-1-氧化物衍生物之光學異構物之腎功能障礙的改善藥
PL424453A1 (pl) * 2018-01-31 2019-08-12 Forty-Four Pharmaceuticals Spółka Z Ograniczoną Odpowiedzialnością Sposoby zmniejszania szkodliwego działania niedoboru perfuzji narządów miąższowych przez inhibitory obojętnej endopeptydazy (NEP) i ludzkiej rozpuszczalnej endopeptydazy (hSEP)
CN112292125B (zh) * 2018-06-22 2023-10-31 西奈克制药有限公司 蛋白尿的治疗

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0254032A3 (en) * 1986-06-20 1990-09-05 Schering Corporation Neutral metalloendopeptidase inhibitors in the treatment of hypertension
DE19510566A1 (de) * 1995-03-23 1996-09-26 Kali Chemie Pharma Gmbh Benzazepin-, Benzoxazepin- und Benzothiazepin-N-essigsäurederivate sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE19638020A1 (de) * 1996-09-18 1998-03-19 Solvay Pharm Gmbh Die gastrointestinale Durchblutung fördernde Arzneimittel
DE19906310A1 (de) * 1999-02-16 2000-08-17 Solvay Pharm Gmbh Arzneimittel zur Behandlung von Bluthochdruck
DE19932555A1 (de) * 1999-07-13 2001-01-18 Solvay Pharm Gmbh Arzneimittel mit protektiver Wirkung gegen oxidativ-toxische und insbesondere gegen kardiotoxische Substanzen
SE9903028D0 (sv) * 1999-08-27 1999-08-27 Astra Ab New use
RU2303041C2 (ru) * 2002-01-16 2007-07-20 Солвей Фармасьютикалс Б.В. Твердые соли бензазепиновых соединений и их применение при получении фармацевтических соединений
PE20040468A1 (es) * 2002-05-17 2004-09-14 Novartis Ag Combinacion de compuestos organicos

Also Published As

Publication number Publication date
JP2007511582A (ja) 2007-05-10
AR046454A1 (es) 2005-12-07
DE602004010172D1 (de) 2007-12-27
PL1687006T3 (pl) 2008-01-31
HK1097762A1 (zh) 2007-07-06
ATE378053T1 (de) 2007-11-15
TW200526228A (en) 2005-08-16
JP4824573B2 (ja) 2011-11-30
AU2004290925A1 (en) 2005-06-02
AU2004290925B2 (en) 2010-07-01
CN1878557A (zh) 2006-12-13
US20050137183A1 (en) 2005-06-23
US7273860B2 (en) 2007-09-25
DE602004010172T2 (de) 2008-09-11
EP1687006B1 (en) 2007-11-14
MXPA06005547A (es) 2006-08-17
TWI344366B (en) 2011-07-01
CA2545802A1 (en) 2005-06-02
BRPI0416706A (pt) 2007-01-16
EP1687006A1 (en) 2006-08-09
WO2005049035A1 (en) 2005-06-02
ES2297536T3 (es) 2008-05-01

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