CN100526310C - 用作杀真菌剂的环丙基-噻吩基-甲酰胺 - Google Patents

用作杀真菌剂的环丙基-噻吩基-甲酰胺 Download PDF

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Publication number
CN100526310C
CN100526310C CNB2003801021700A CN200380102170A CN100526310C CN 100526310 C CN100526310 C CN 100526310C CN B2003801021700 A CNB2003801021700 A CN B2003801021700A CN 200380102170 A CN200380102170 A CN 200380102170A CN 100526310 C CN100526310 C CN 100526310C
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CN
China
Prior art keywords
sub
alkyl
formula
halogen
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB2003801021700A
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English (en)
Chinese (zh)
Other versions
CN1708496A (zh
Inventor
J·埃伦弗兰德
H·托布勒
H·沃尔特
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Syngenta Participations AG
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Syngenta Participations AG
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Publication of CN1708496A publication Critical patent/CN1708496A/zh
Application granted granted Critical
Publication of CN100526310C publication Critical patent/CN100526310C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30Hetero atoms other than halogen
    • C07D333/36Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D411/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CNB2003801021700A 2002-11-01 2003-10-24 用作杀真菌剂的环丙基-噻吩基-甲酰胺 Expired - Fee Related CN100526310C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0225554.5 2002-11-01
GBGB0225554.5A GB0225554D0 (en) 2002-11-01 2002-11-01 Chemical compounds

Publications (2)

Publication Number Publication Date
CN1708496A CN1708496A (zh) 2005-12-14
CN100526310C true CN100526310C (zh) 2009-08-12

Family

ID=9947074

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB2003801021700A Expired - Fee Related CN100526310C (zh) 2002-11-01 2003-10-24 用作杀真菌剂的环丙基-噻吩基-甲酰胺

Country Status (23)

Country Link
US (1) US7312179B2 (https=)
EP (1) EP1556377B1 (https=)
JP (1) JP4673061B2 (https=)
KR (1) KR101000731B1 (https=)
CN (1) CN100526310C (https=)
AR (1) AR041747A1 (https=)
AT (1) ATE331714T1 (https=)
AU (1) AU2003286140A1 (https=)
BR (1) BR0315857A (https=)
CA (1) CA2501739C (https=)
CO (1) CO5550397A2 (https=)
DE (1) DE60306540T2 (https=)
DK (1) DK1556377T3 (https=)
EC (1) ECSP055770A (https=)
ES (1) ES2266881T3 (https=)
GB (1) GB0225554D0 (https=)
GT (1) GT200300236A (https=)
MX (1) MXPA05004463A (https=)
PT (1) PT1556377E (https=)
RU (1) RU2005116974A (https=)
TW (1) TW200412848A (https=)
WO (1) WO2004039799A1 (https=)
ZA (1) ZA200502644B (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0418047D0 (en) 2004-08-12 2004-09-15 Syngenta Participations Ag Fungicidal compositions
DE102005025989A1 (de) * 2005-06-07 2007-01-11 Bayer Cropscience Ag Carboxamide
DE602006008976D1 (de) * 2005-11-15 2009-10-15 Syngenta Participations Ag Verfahren zur herstellung von carboxaniliden
WO2007057139A1 (en) * 2005-11-15 2007-05-24 Syngenta Participations Ag Microbiocides
AU2011248579A1 (en) 2010-04-27 2012-11-29 Calcimedica, Inc. Compounds that modulate intracellular calcium
US10703722B2 (en) 2010-04-27 2020-07-07 Calcimedica, Inc. Compounds that modulate intracellular calcium
DK2563776T3 (en) 2010-04-27 2016-09-19 Calcimedica Inc Relations that modulate intracellular calcium
EP2609095A4 (en) 2010-08-27 2014-06-18 Calcimedica Inc COMPOUNDS MODULATING INTRACELLULAR CALCIUM
US20130231303A1 (en) * 2010-11-15 2013-09-05 Bayer Intellectual Property Gmbh 5-halogenopyrazole(thio)carboxamides
US20120316182A1 (en) 2011-06-10 2012-12-13 Calcimedica, Inc. Compounds that modulate intracellular calcium
US9856240B2 (en) 2011-10-19 2018-01-02 Calcimedica, Inc. Compounds that modulate intracellular calcium
WO2014059333A1 (en) 2012-10-12 2014-04-17 Calcimedica, Inc. Compounds that modulate intracellular calcium
ES3033759T3 (en) 2015-02-27 2025-08-07 Calcimedica Inc Pancreatitis treatment
CA2995094A1 (en) 2015-08-07 2017-02-16 Calcimedica, Inc. Use of crac channel inhibitors for the treatment of stroke and traumatic brain injury
CN106977457A (zh) * 2016-12-22 2017-07-25 浙江海正化工股份有限公司 一种3‑二氟甲基‑1‑甲基‑吡唑‑4‑甲酸及其合成方法
EP3818051B1 (en) * 2018-07-05 2022-08-03 Bayer Aktiengesellschaft Substituted thiophenecarboxamides and analogues as antibacterials agents
CA3172249A1 (en) 2020-03-20 2021-09-23 Calcimedica, Inc. Methods and compositions for treating acute lung injury and acute respiratory distress syndrome
CA3198798A1 (en) 2020-11-13 2022-05-19 Kenneth Stauderman Improved synthesis of crac channel inhibitors

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2126587A (en) * 1982-09-13 1984-03-28 Sandoz Ltd Fungicidal thiophene derivatives
US4743602A (en) * 1986-07-16 1988-05-10 Imperial Chemical Industries Plc Thiophene cyclopropyl amine compounds, compositions and fungicidal use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2385721A1 (fr) * 1977-03-31 1978-10-27 Hexachimie Cyclopropyl-6 dihydro-1,3 methyl-1 phenyl-5 oxo-2 2 h-thieno (2,3-e) diazepine, son procede de preparation et son application en therapeutique
GB8617378D0 (en) * 1986-07-16 1986-08-20 Ici Plc Tertiary amine compounds
DE69618370T2 (de) * 1995-04-11 2002-09-26 Mitsui Chemicals, Inc. Substituierte Thiophenderivate und diese als aktiver Bestandteil enthaltenden Fungizide für Land- und Gartenbauwirtschaft
GB9817548D0 (en) * 1998-08-12 1998-10-07 Novartis Ag Organic compounds
GB9930750D0 (en) * 1999-12-29 2000-02-16 Novartis Ag Organic compounds
MXPA04008314A (es) 2002-03-05 2004-11-26 Syngenta Participations Ag O-ciclopropil-carboxaniluros y su uso como funguicidas.
WO2004018438A2 (en) 2002-08-22 2004-03-04 Syngenta Participations Ag Microbiocidal (e.g. fungicidal) 1,2,3-triazole derivatives

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2126587A (en) * 1982-09-13 1984-03-28 Sandoz Ltd Fungicidal thiophene derivatives
US4743602A (en) * 1986-07-16 1988-05-10 Imperial Chemical Industries Plc Thiophene cyclopropyl amine compounds, compositions and fungicidal use

Also Published As

Publication number Publication date
GT200300236A (es) 2004-06-23
KR101000731B1 (ko) 2010-12-14
KR20050071648A (ko) 2005-07-07
DK1556377T3 (da) 2006-10-23
JP4673061B2 (ja) 2011-04-20
CA2501739A1 (en) 2004-05-13
BR0315857A (pt) 2005-09-20
DE60306540D1 (en) 2006-08-10
EP1556377B1 (en) 2006-06-28
DE60306540T2 (de) 2007-06-28
US20060030567A1 (en) 2006-02-09
CA2501739C (en) 2011-04-12
CN1708496A (zh) 2005-12-14
AU2003286140A1 (en) 2004-05-25
ZA200502644B (en) 2005-11-23
ES2266881T3 (es) 2007-03-01
JP2006508089A (ja) 2006-03-09
TW200412848A (en) 2004-08-01
CO5550397A2 (es) 2005-08-31
WO2004039799A1 (en) 2004-05-13
PT1556377E (pt) 2006-10-31
MXPA05004463A (es) 2005-07-26
RU2005116974A (ru) 2006-03-27
GB0225554D0 (en) 2002-12-11
ECSP055770A (es) 2005-08-11
AR041747A1 (es) 2005-05-26
ATE331714T1 (de) 2006-07-15
EP1556377A1 (en) 2005-07-27
US7312179B2 (en) 2007-12-25

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PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
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GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20090812

Termination date: 20131024