Summary of the invention
The objective of the invention is to provide a kind of at above-mentioned deficiency can treat simultaneously to middle-aged and elderly people hyperlipidemia, hypertension, hyperglycemia disease, and be free from side effects, to not infringement of human body, have nourishing the liver and kidney, defying age, medicine and preparation method thereof in the nutrition of three-hypers falls.
For achieving the above object, invigorating the liver and kidney defying age of the present invention falls that medicine each component (by weight) proportioning is in the three-hypers nutrition: Radix Panacis Quinquefolii 3-8, Arillus Longan 6-12, Fructus Hippophae 6-12, Herba Apocyni veneti 10-15, Radix Salviae Miltiorrhizae 10-20, Radix Puerariae 10-20, Rhizoma Polygonati 12-25, Semen Cassiae 15-25, Fructus Crataegi 20-30, Fructus Mori 15-20 Cordyceps 2-8, Flos Chrysanthemi 3-6, xylitol 10-30.
Preferred component of the present invention (by weight) proportioning is:
5 parts of Radix Panacis Quinquefoliis, 8 parts of Arillus Longans, 10 parts of Fructus Hippophaes, 13 parts of Herba Apocyni venetis, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Puerariaes, 20 parts of Rhizoma Polygonatis, 20 parts of Semen Cassiaes, 25 parts of Fructus Crataegis, 18 parts in Fructus Mori, 5 parts of Cordyceps, 5 parts of Flos Chrysanthemis, 20 parts of xylitol.
The preparation method that medicine in the three-hypers nutrition falls in the invigorating the liver and kidney defying age is:
1, extracts
With Radix Panacis Quinquefolii, Arillus Longan, Fructus Hippophae, Herba Apocyni veneti, Radix Salviae Miltiorrhizae, Radix Puerariae, Rhizoma Polygonati,, after Semen Cassiae, Fructus Crataegi, Fructus Mori, Cordyceps, Flos Chrysanthemi clean with clear water, pulverize the granulating lobe and place rustless steel to extract still, add 10 times of tap waters for the first time after, heating decocts extracted 1.5 hours, separation and Extraction liquid, pressure filtration, filtrate for later use, for the second time add 8 times of tap waters after, heating decocts extracted 1 hour, separation and Extraction liquid, pressure filtration, filtrate for later use;
2, concentrate
Extracted twice liquid is merged, place in the vacuum high energy evaporation concentrator, decompression (negative 200mmHg), standby;
3, the preparation of dry powder
80-100 ℃ of Chinese medicine extraction liquid mixing post-heating, under the constant temperature dry 2-3 hour;
4, granulate
The material that crushes is added xylitol inserts in the granulator and granulates;
5, packing, sterilization, warehouse-in
60C
0Radiation 8KGy, check, warehouse-in.
Medical science thinks that hypertension can cause arteriosclerosis, makes blood vessel wall coarse, and cerebral arteries narrows down, the thrombosed main cause of occluding vascular.Add that on this basis blood pressure is low, blood fat viscosity height, slow blood flow (as heart failure, shock, fatigue, sleep quality) blood cramp disease or solidify such as increase at factor, just form the thrombosis disease.Modern medicine thinks that endangering person in middle and old age people healthy is exactly three-hypers disease.Hypertension can cause the tremulous pulse premature cure; Hyperlipidemia is that blood viscosity is big, and blood is not smooth, and the obstructing arterial blood vessel makes arterial tissue's ischemia, and apoplexy occurs.Age of onset is many at mid-aged population.
This invigorating the liver and kidney defying age falls that medicine is a monarch drug with natural Chinese medicines Radix Panacis Quinquefolii, Arillus Longan, Fructus Hippophae, Cordyceps in the three-hypers nutrition, nourishing the liver and kidney, strongly invigorating primordial QI defying age; With Herba Apocyni veneti, Radix Salviae Miltiorrhizae, Radix Puerariae, Rhizoma Polygonati, Fructus Mori is ministerial drug, YIN nourishing nourishing the liver, blood pressure lowering blood sugar lowering; With Semen Cassiae, Fructus Crataegi, Flos Chrysanthemi is adjuvant drug, clearing away heat to improve acuity of vision, blood circulation promoting and blood stasis dispelling, blood fat reducing; With the xylitol is messenger drug, and auxiliary all medicines increase drug effect.The all medicines of above-mentioned monarch are reasonably combined, are rich in the multiple nutrients composition, and overall efficacy nourishing the liver and kidney, defying age, blood pressure lowering, blood fat reducing, blood sugar lowering, clear benefit make eye bright, loosening bowel to relieve constipation.
Wherein, Radix Panacis Quinquefolii: sweet, little hardship, cold.GUIXIN, lung, kidney channel, boosting qi and nourishing yin, clearing away heat and promoting production of body fluid.It is thanks to cloudy to be used for the deficiency of vital energy, interior-heat, and cough with asthma expectorant blood, deficiency-heat is tired tired, quenches one's thirst dryness of the mouth and throat.Arillus Longan: Gan Wen, GUIXIN, spleen channel.The reinforcing the heart strengthening the spleen, nourishing blood to tranquillize the mind, be used for worn with age, insufficiency of vital energy and blood weak breath asthenia, the feel frustrated diseases such as insomnia forgetfulness of blood deficiency of severe palpitation and heart spleen two.Fructus Hippophae: suffering, temperature attaches to the lung and stomach meridians, dispersing wind and cold, clearing the nasal passage.Be used for headche due to wind-cold, nasal obstruction, nasal sinusitis, turbid nasal discharge.Herba Apocyni veneti: sweet, bitter, cold.Return Liver Channel.Clearing away liver-fire, suppressing the hyperactive liver to relieve the wind syndrome are used for dizzy, the convulsion with spasms of the flourishing headache of liver-fire, and this product has the effect that brings high blood pressure down.Radix Salviae Miltiorrhizae: hardship is slightly cold.GUIXIN, Liver Channel.Stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire.Be used for menoxenia, amenorrhea dysmenorrhea , WEIJIA is gathered, breast ventral spine pain, and pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia, hepatosplenomegaly, angina pectoris.Radix Puerariae: sweet, hot, cool, return spleen, stomach warp.Expelling pathogenic factors from muscles for reducing heat promotes the production of body fluid, rash, yang invigorating antidiarrheal.Be used for fever caused by exogenous pathogens headache, tanacity, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea is had loose bowels; The hypertension neck pain.Effect to blood circulation: the separation energy that proposes in the Radix Puerariae increases brain and crown vascular flow, behind the anesthesia Canis familiaris L. internal carotid artery injection Radix Puerariae flavone, cerebral blood flow increases, the corresponding reduction of vascular resistance is after effect is kept 2-30 minute, as intravenous injection, then the cerebral blood flow increase is lighter, also have and can remove epinephrine and the pressor effect of norepinephrine, but then can improve cerebral circulation the hypertensive arteriosclerosis patient, its action temperature and.Radix Puerariae flavone and kudzuvine root wine cream are injected in coronary artery and the vein of Canis familiaris L., and the coronary vasodilator flow is increased, and vascular resistance reduces.Change the crystallization that proposes in rat abdominal cavity and subcutaneous injection kudzuvine root wine extractum and its water decoction of lumbar injection and the Radix Puerariae, caused heart ischemia reaction all has protective effect to pituitrin, and the Radix Puerariae water decoction is oral not to have tangible hypotensive effect to the hypertension Canis familiaris L..The a tree name report has excitement and suppresses two kinds of compositions of heart in Radix Puerariae (Japan produces) decoct.Rhizoma Polygonati: sweet, flat.Go into the heart, spleen, lung, kidney, cure mainly tonification gas, profit cardiopulmonary, bone and muscle strengthening.Control deficient cold and heat, pulmonary tuberculosis hemoptysis, the empty lack of appetite of body after being ill, muscles and bones weakness, rheumatalgia, wind favus disease.The mucous matter of Rhizoma Polygonati rhizome, starch and sugar.Capsule silk Rhizoma Polygonati rhizome contains azete carboxylic acid, aspartic acid, homoserine, DAB, digitalis glucoside and multiple anthraquinone analog compound.Rhizoma Polygonati milk stem contains Yan acid, phlegmatic temperament, quinones.Other contains polygonatum polysaccharide first, second, the third, Rhizoma Polygonati oligosaccharide first, second, third.Polysaccharide first, second, third by glucose, mannose, galacturonic acid in conjunction with and; Oligosaccharide first, second, third is by glucose and fructose be combined into.The methanolic extract of rhizome has 11 seed amino acids such as lysine by analysis.Semen Cassiae: bitter sweet, cold.Liver heat removing makes eye bright, diuretic, relieving constipation.Have hypotensive activity and antibacterial action and control wind heat acute conjunctivitis, optic atrohic blindness, nyctalopia, hypertension, hepatitis, cirrhotic ascites, habitual constipation.Fresh seeds contains chrysophanol, emodin, aloe-emodin, emodin, emodin monoglucoside, emodin anthrone, physcione, obtusin, aurantio-obtusin.Fructus Crataegi: sweet in the mouth, acid, warm in nature, return spleen, stomach, Liver Channel, be mainly used to meat stagnation, relieving dyspepsia, eliminating stasis to stop pain etc.Main Crataegolic acid, tartaric acid, citric acid, flavonoid lactone, glycoside, lipolytic enzyme and the saccharide of containing.Modern pharmacological research shows that Fructus Crataegi can increase enzyme secretion in the stomach, facilitating digestion, and contained fat splitting enzyme can promote the digestion of fat food.Fructus Mori; Nature and flavor: sweet, cold.Go into liver, kidney channel.Cure mainly: tonifying liver, kidney tonifying, relieve dizziness, high fever, infantile convulsions, epilepsy, etc., grow liquid.The treating the liver kidney yin is lost, quenches one's thirst, and constipation, order is dark, tinnitus, scrofula, articular instability.Nourishing YIN blood, liver and kidney tonifying, intestine moistening.Contain sugar, tannic acid, malic acid and vitamin B1, B2, C carotene.The fatty acid of Fructus Mori oil mainly is made up of linoleic acid and a spot of stearic acid, oleic acid etc.Cordyceps: warm in nature, sweet in the mouth, flat.Function with invigorating the lung and the kidney, hemostasis and phlegm.Be used for chronic cough dyspnea due to deficiency, chronic cough spitting of blood, impotence and seminal emission, soreness of waist and knee joint.Cordyceps is the valuable tonic in the conventional Chinese medicine.Flos Chrysanthemi: sweet in the mouth, hardship, cool in nature.Have heat-clearing and toxic substances removing, the nourishing the liver that makes eye bright, QI invigorating strengthening the spleen, effects such as skin and complexion improving skin care., furuncle swelling toxin dim-sighted to conjunctival congestion and hypertension also have effect.
The specific embodiment
Embodiment 1
Invigorating the liver and kidney defying age of the present invention falls that medicine each component (by weight) proportioning is in the three-hypers nutrition: Radix Panacis Quinquefolii 3-8, Arillus Longan 6-12, Fructus Hippophae 6-12, Herba Apocyni veneti 10-15, Radix Salviae Miltiorrhizae 10-20, Radix Puerariae 10-20, Rhizoma Polygonati 12-25, Semen Cassiae 15-25, Fructus Crataegi 20-30, Fructus Mori 15-20, Cordyceps 2-8, Flos Chrysanthemi 3-6, xylitol 10-30.
Embodiment 2
The invigorating the liver and kidney defying age falls that medicine each component (by weight) proportioning is in the three-hypers nutrition:
3 parts of Radix Panacis Quinquefoliis, 6 parts of Arillus Longans, 6 parts of Fructus Hippophaes, 10 parts of Herba Apocyni venetis, 10 parts of 10 parts of Radix Puerariaes of Radix Salviae Miltiorrhizae, 12 parts of Rhizoma Polygonatis, 15 parts of Semen Cassiaes, 20 parts of Fructus Crataegis, 15 parts in Fructus Mori, 2 parts of Cordyceps, 3 parts of Flos Chrysanthemis, 10 parts of xylitol.
Embodiment 3
The invigorating the liver and kidney defying age falls that medicine each component (by weight) proportioning is in the three-hypers nutrition: 8 parts of Radix Panacis Quinquefoliis, 12 parts of Arillus Longans, 12 parts of Fructus Hippophaes, 15 parts of Herba Apocyni venetis, 20 parts of Radix Salviae Miltiorrhizaes, 20 parts of Radix Puerariaes, 25 parts of Rhizoma Polygonatis, 25 parts of Semen Cassiaes, 30 parts of Fructus Crataegis, 20 parts in Fructus Mori, 8 parts of Cordyceps, 6 parts of Flos Chrysanthemis, 30 parts of xylitol.
Embodiment 4
Preferred component of the present invention (by weight) proportioning is: 5 parts of Radix Panacis Quinquefoliis, 8 parts of Arillus Longans, 10 parts of Fructus Hippophaes, 13 parts of Herba Apocyni venetis, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Puerariaes, 20 parts of Rhizoma Polygonatis, 20 parts of Semen Cassiaes, 25 parts of Fructus Crataegis, 18 parts in Fructus Mori, 5 parts of Cordyceps, 5 parts of Flos Chrysanthemis, 20 parts of xylitol.
Above-mentioned invigorating the liver and kidney defying age as shown in Figure 1 falls that the medicine preparation method is in the three-hypers nutrition:
1, extracts
With Radix Panacis Quinquefolii, Arillus Longan, Fructus Hippophae, Herba Apocyni veneti, Radix Salviae Miltiorrhizae, Radix Puerariae, Rhizoma Polygonati,, after Semen Cassiae, Fructus Crataegi, Fructus Mori, Cordyceps, Flos Chrysanthemi clean with clear water, pulverize the granulating lobe and place rustless steel to extract still, add 10 times of tap waters for the first time after, heating decocts extracted 1.5 hours, separation and Extraction liquid, pressure filtration, filtrate for later use, for the second time add 8 times of tap waters after, heating decocts extracted 1 hour, separation and Extraction liquid, pressure filtration, filtrate for later use;
2, concentrate
Extracted twice liquid is merged, place in the vacuum high energy evaporation concentrator, decompression (negative 200mmHg), standby;
3, the preparation of dry powder
80-100 ℃ of Chinese medicine extraction liquid mixing post-heating, under the constant temperature dry 2-3 hour;
4, granulate
The material that crushes is added xylitol inserts in the granulator and granulates;
5, packing, sterilization, warehouse-in
60C
0Radiation 8KGy, check, warehouse-in.
It is evident in efficacy in clinical practice to fall in the three-hypers nutrition medicine with the invigorating the liver and kidney defying age of method for preparing, and the patient with hypertension, hyperlipidemia, hyperglycemia all can be treated and have no side effect.As:
Case (one) patient Lee xx man, 60 years old, height 170cm, 86 kilograms of body weight.Dizzy three months, when tired more very, sensation of oppression over the chest with shortness of breath, constipation.Blood pressure 168/106mmHg, stringy and thready pulse, body of the tongue is dim red, only can adhere to part-time employment, part-time job, part-time work, manages first visit on June 7 in 2004.Laboratory examination: cholesterol 320mg/dl, low density lipoprotein, LDL 157.8mg/dl, three acid glycerol 96mg/dl are diagnosed as hyperlipidemia, vascular hypertension.Give among the present invention medicine and take two months (taking medicine by the previous moon, it is relatively good to adhere to, intermittently takes in back one month) continuously.Body weight is reduced to 72 kilograms, and blood pressure is reduced to 116/78mmHg, and the arteries and veins tongue is normal, patient and feel that symptom dizzy and uncomfortable in chest eliminates, and cholesterol is reduced to 289mg/dl, and low density lipoprotein, LDL is reduced to 143mg/dl, three acid glycerol 75mg/dl, patient can normally go to work, and is healthy.
The old xx of case (two) diabetes (clinical observation 56 examples), woman, 52 years old, examine in the spring in 2003, body constitution is become thin, myasthenia of limbs; frequency of micturition, and yellowish complexion is refreshing weary, go certain examination in hospital be diagnosed as glycosuria disease (glucose in urine +++; blood glucose 320mg/dl); in taking the present invention, take the D860 medicine before the medicine, one week the back consciously feels to have the apparent side effect reaction, after use medicine among the present invention instead; take that symptom is clearly better after one month; chemical examination glucose in urine (++) blood glucose 175mg/dl, doctor's advice continues to take medicine among the present invention in two months, recovers normal fully; weight gain; the spirit multiplication, does chemical examination again, and glucose in urine is turned out cloudy; blood glucose 130mg/dl, patient is almost recovered.Advise it to continue to take to consolidate curative effect.Follow up a case by regular visits to after the drug withdrawal and do not see recurrence in 2 years.
Case (three) vascular hypertension.62 years old Nanyang citizen of king XX woman, find hypertension 170/100mmHg before the Yu Sinian, informal dress Western medicine depressor controlling blood pressure, private prosecution has headache at ordinary times, feel sick, diseases such as insomnia and dreamful sleep, Chest X-rays does not have unusually, electrocardiogram is abnormal change not, and blood fat is not high, edema of lower limbs I degree, the enlarged tongue color is light, stringy and thready pulse is diagnosed as the essential hypertension I phase, and the Western medicine depressor of stopping using is used Chinese medicine product of the present invention instead and taken a course of treatment (one month), blood pressure obviously drops to 130/90mmHg, take medicine continuously after two months, blood pressure recovers normal 120/82mmHg, observes five months blood pressures after the drug withdrawal and does not rise.