CN100428920C - 外科植入物 - Google Patents
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- CN100428920C CN100428920C CNB038074761A CN03807476A CN100428920C CN 100428920 C CN100428920 C CN 100428920C CN B038074761 A CNB038074761 A CN B038074761A CN 03807476 A CN03807476 A CN 03807476A CN 100428920 C CN100428920 C CN 100428920C
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- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/4455—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
- A61F2/4465—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages having a circular or kidney shaped cross-section substantially perpendicular to the axis of the spine
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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Abstract
本发明涉及一种椎间植入物形式的外科植入物(1),具有多个用来容纳骨替代材料的空腔(2)。骨替代材料是完全人工合成的物质。植入物具有一个顶面和一个底面,空腔将顶面与底面相连,空腔(2)朝向植入物(1)的顶面锥形或楔形扩大。因此可实现这样的优点,即,不再存在在选择天然物质的骨替代材料时传染的危险,此外,通过选用合成骨替代材料使其物理性能不再波动(孔隙度、孔隙直径、机械抗压强度)。
Description
技术领域
本发明涉及一种外科植入物,特别是椎间植入物、髓内钉或内置关节假体。
背景技术
椎间植入物或其他外科植入物具有与骨构成的空腔,其在大多数情况下通过手术用骨或类似于骨的材料填充,以便能够最佳地生长(对椎间植入物,就是所谓的两个椎骨体的长合)。
以下技术是现有技术:
a)填充从患者骨盆腔上提取下来的自身固有的(autologe)骨屑;这种方式对于患者常常带来附加的发病率。
b)植入物用自身固有的骨填充,对于椎间植入物的情况,这种骨通过身体腹面的(anteriore)开口从相邻椎骨体上提取。
c)用类似于骨的材料填充植入物。这可以是天然的或完全合成的物质。在天然物质的情况下,不管是对于同种异基因(allogene)材料、还是对于异种(xenogene)材料都存在传染疾病的危险。此外,由于不同的物质特殊性及其在身体上的提取部位,骨替代材料的物理性能具有很大的波动。
现有技术的上述讨论仅仅用来说明本发明的背景,并不意味着所提到的现有技术在本申请或其优先权提出的时刻也实际发表或公知。
发明内容
在这里本发明提供一种改进方法。本发明的目的是,制造一种植入物,它在其供给的形式中,以完全人工合成为基础的骨替代材料已经包含在一种复合产品形式的植入物本身内。
本发明提出一种具有至少一个用来容纳骨替代材料的空腔的外科植入物,所述骨替代材料是完全人工合成的物质,植入物具有一个顶面和一个底面,空腔将顶面与底面相连,其特征为:空腔朝向植入物的顶面锥形或楔形扩大。
本发明可以借助于采用完全人工合成的骨替代材料防止上面所提到的所有缺点。由此可以达到这样的优点,即,与天然物质的骨替代产品相比,由于不存在可能引起疾病的朊、病菌、病毒或细菌,故不存在传染疾病的危险。
完全人工合成的骨替代材料最好由磷酸钙,典型地由β-磷酸三钙组成。它有这样的优点,即,采用一种陶瓷,其化学计量学的成分基本上相当于人骨的成分。再者,β-磷酸三钙的降解时间既不太快也不太慢,从而不会在降解过程中形成空腔或植入物残渣。
本发明对于患者带来其他的优点。这归功于手术的简化,特别是表现在:达到
a)显著缩短手术时间;
b)缩短的麻醉时间;
c)减少患者的失血,
此外通过选择合成骨替代材料,使其物理性能(孔隙率、孔隙大小、机械抗压强度)不会出现波动。
骨替代材料既可以相应于空腔几何特征的刚性实体形式、也可以可塑性变形的可填入空腔的物质的形式存在。
在一种特别的实施形式中,植入物的空腔朝植入物的顶面或底面锥形或楔形扩大。因此填入空腔的完全人工合成的骨替代材料实体在空腔内得到牢固的压配合。
但是实体也可以用合适的固定装置,尤其是螺钉或销钉或锁紧装置固定在空腔内。
植入物可以具有一单独的空腔或许多个、通常是2至8个相互隔开的空腔。
植入物最好做成椎间植入物,但是也可以做成髓内钉或其他人造骨植入体或内置关节假体的形式。
在做成椎间植入物的一种结构中,它最好做成筐笼形,它具有一顶面和一底面,这二个面适合于用来贴合在两个相邻椎骨体的端板上。在这种情况下空腔将筐笼的顶面与底面连接。筐笼的顶面和/或底面适宜于具有一种三维构造,例如条纹、凹槽、粒结或其他突起或凹陷的形状。
植入物最好由一种透X光的材料特别是聚合物例如PEEK组成。其优点在于,可以进行长合的临床判定。
一种优选的改进结构在于,骨替代材料由一种可吸收材料,尤其是由羟基磷灰石(Hydroxylapatit)或磷酸三钙组成。这有这样的优点,即,可以通过材料的吸收长出新的骨组织,而不必强制穿过永久材料的孔隙。
由骨替代材料组成的实体最好具有至少25%、通常至少35%的孔隙率,其中至少50%的孔隙应该具有200至500微米范围内的直径。在另一种实施形式中,骨替代材料在各个孔隙之间具有连接通道,它们具有在10至500微米、尤其是200至400微米范围内的直径。
植入物的制造例如可以通过这样的方法进行,即,由完全人工合成的骨替代材料组成的相应于空腔几何形状的刚性实体压入植入物的空腔中,或者用固定装置固定于其中。按照另一种方法,将可成形的尤其是可塑造的完全人工合成的物质,尤其是以颗粒状存在的骨替代材料,装入空腔内,并以未硬化或硬化的状态保留在那里。后一种方法也适合于通过手术用骨替代材料填充空腔。
附图说明
下面借助于一个实施例的局部示意图较详细地说明本发明和按本发明的改进结构。
附图表示:
图1未填充状态的植入物的透视图;
图2填充状态的植入物的透视图;
图3按图2的植入物沿III-III线的纵剖视。
具体实施方式
图1至3中所示的植入物是一带有四个相互分开的空腔2的筐笼形椎间植入物,空腔连接着筐笼的顶面4和底面5。顶面4和底面5确定用来贴合在两个相邻椎骨体的端板上,并且局部具有粒结形状的三维构造。
如图3可见,空腔2朝植入物1的顶面4楔形或金字塔形或锥形扩大,并如图2所示,包含有几何特征相应地成形的、由完全人工合成的骨替代材料组成的实体3。实体3借助于牢固的压配合支承在空腔2内。
筐笼由聚醚醚酮(PEEK)组成,而实体3由多孔的羟基磷灰石组成。
Claims (18)
1.具有至少一个用来容纳骨替代材料的空腔(2)的外科植入物(1),所述骨替代材料是完全人工合成的物质,植入物(1)具有一个顶面(4)和一个底面(5),空腔(2)将顶面(4)与底面(5)相连,其特征为:空腔(2)朝向植入物(1)的顶面锥形或楔形扩大。
2.按权利要求1的植入物(1),其特征为:所述植入物具有2至8个相互隔开的空腔(2)。
3.按权利要求1的植入物(1),其特征为:所述植入物由一种透X光的材料组成。
4.按权利要求3的植入物(1),其特征为:所述植入物由聚醚醚酮组成。
5.按权利要求1的植入物(1),其特征为:所述植入物做成椎间植入物。
6.按权利要求5的植入物(1),其特征为:所述植入物做成筐笼,该筐笼具有所述顶面(4)和所述底面(5),这二个面适合于贴合在两个相邻椎骨体的端板上。
7.按权利要求1至6任一项的的植入物(1),其特征为:顶面(4)和/或底面(5)具有一种三维构造(6)。
8.按权利要求1的植入物(1),其特征为:至少一个空腔(2)填充一种完全人工合成物质构成的骨替代材料。
9.按权利要求8的植入物(1),其特征为:骨替代材料以相应于空腔(2)几何特征的刚性实体(3)的形式存在。
10.按权利要求9的植入物(1),其特征为:实体(3)借助于牢固的压配合支承在空腔(2)内。
11.按权利要求9的植入物(1),其特征为:实体(3)用一固定装置固定在空腔(2)内。
12.按权利要求8的植入物(1),其特征为:骨替代材料以可塑性变形的、可填充到空腔(2)内的物质的形式存在。
13.按权利要求9的植入物(1),其特征为:实体(3)由一种骨替代材料组成,该骨替代材料至少部分由可生物吸收的材料组成。
14.按权利要求9的植入物(1),其特征为:实体(3)由一种具有至少25%的孔隙率的骨替代材料组成。
15.按权利要求9的植入物(1),其特征为:实体(3)由一种多孔的骨替代材料组成,其中至少50%的孔隙具有在200至500微米范围内的直径。
16.按权利要求9的植入物(1),其特征为:实体(3)由一种在各个孔隙之间具有连接通道的骨替代材料组成,这些孔隙具有从10至500微米范围内的直径。
17.用于制造按权利要求9的植入物的方法,其特征为:将一种相应于空腔(2)几何特征的、由完全人工合成的骨替代材料组成的刚性实体(3)压入植入物的空腔(2)中。
18.用于制造按权利要求1的植入物的方法,其特征为:将一种可成形的、可塑性变形的、完全人工合成的物质装入空腔(2)中,该物质是以颗粒状存在的骨替代材料。
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DE20205016U DE20205016U1 (de) | 2002-03-30 | 2002-03-30 | Chirurgisches Implantat |
DE20205016.5 | 2002-03-30 |
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EP (1) | EP1490001A1 (zh) |
JP (1) | JP2005529634A (zh) |
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CN (1) | CN100428920C (zh) |
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DE (1) | DE20205016U1 (zh) |
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NZ (1) | NZ535475A (zh) |
RU (1) | RU2004131849A (zh) |
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Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7597715B2 (en) | 2005-04-21 | 2009-10-06 | Biomet Manufacturing Corp. | Method and apparatus for use of porous implants |
US8123814B2 (en) * | 2001-02-23 | 2012-02-28 | Biomet Manufacturing Corp. | Method and appartus for acetabular reconstruction |
WO2004084742A1 (en) | 2003-03-24 | 2004-10-07 | Theken Surgical Llc | Spinal implant adjustment device |
US20050065607A1 (en) * | 2003-09-24 | 2005-03-24 | Gross Jeffrey M. | Assembled fusion implant |
JP2005124709A (ja) * | 2003-10-22 | 2005-05-19 | Olympus Corp | 生体組織補填材及びその製造方法 |
WO2005048897A1 (en) * | 2003-11-18 | 2005-06-02 | Quantum Orthopedics | Osteoconductive integrated spinal cage and method of making same |
US20070185585A1 (en) * | 2004-03-09 | 2007-08-09 | Brat Bracy | Implant Scaffold Combined With Autologous Tissue, Allogenic Tissue, Cultured Tissue, or combinations Thereof |
US7833271B2 (en) * | 2004-05-04 | 2010-11-16 | Zimmer Spine, Inc. | Spinal implants with body and insert |
US8021432B2 (en) * | 2005-12-05 | 2011-09-20 | Biomet Manufacturing Corp. | Apparatus for use of porous implants |
US8292967B2 (en) | 2005-04-21 | 2012-10-23 | Biomet Manufacturing Corp. | Method and apparatus for use of porous implants |
US8266780B2 (en) | 2005-04-21 | 2012-09-18 | Biomet Manufacturing Corp. | Method and apparatus for use of porous implants |
US8066778B2 (en) | 2005-04-21 | 2011-11-29 | Biomet Manufacturing Corp. | Porous metal cup with cobalt bearing surface |
US8092548B2 (en) * | 2005-06-22 | 2012-01-10 | Warsaw Orthopedic, Inc. | Osteograft treatment to promote osteoinduction and osteograft incorporation |
WO2007044229A2 (en) * | 2005-09-28 | 2007-04-19 | Calcitec, Inc. | Surface treatments for calcium phosphate-based implants |
US8257395B2 (en) * | 2007-09-21 | 2012-09-04 | Jmea Corporation | Spinal fixation with selectively applied bone growth promoting agent |
US20090048675A1 (en) * | 2007-04-25 | 2009-02-19 | Bhatnagar Mohit K | Spinal Fusion Implants with Selectively Applied Bone Growth Promoting Agent |
US8241357B2 (en) | 2007-04-25 | 2012-08-14 | Jmea Corporation | Prosthesis with a selectively applied bone growth promoting agent |
AU2009210750A1 (en) * | 2008-02-01 | 2009-08-13 | Synthes Gmbh | Porous biocompatible polymer material and methods |
EP2273952B1 (en) | 2008-04-02 | 2018-02-21 | Pioneer Surgical Technology, Inc. | Intervertebral implant devices for supporting vertebrae and devices for insertion thereof |
EP2198796A1 (de) * | 2008-12-19 | 2010-06-23 | Sepitec Foundation | Knochenschraube |
US8821555B2 (en) | 2009-02-11 | 2014-09-02 | Howmedica Osteonics Corp. | Intervertebral implant with integrated fixation |
DK2453939T3 (da) * | 2009-07-16 | 2014-02-03 | Anatoli D Dosta | Knogleimplantater |
JP5942076B2 (ja) | 2010-11-10 | 2016-06-29 | 三菱マテリアル株式会社 | 椎体スペーサ |
WO2012063863A1 (ja) * | 2010-11-10 | 2012-05-18 | Hoya株式会社 | 椎体スペーサ |
WO2012063868A1 (ja) | 2010-11-10 | 2012-05-18 | Hoya株式会社 | 椎体スペーサ |
KR101326054B1 (ko) * | 2011-09-23 | 2013-11-07 | 서울대학교산학협력단 | 척추용 임플란트 |
JP6008643B2 (ja) * | 2012-07-31 | 2016-10-19 | 京セラメディカル株式会社 | 生体インプラント材料の製造方法および生体インプラント材料 |
US9566169B2 (en) | 2014-03-13 | 2017-02-14 | DePuy Synthes Products, Inc. | ACIS allograft designs |
AU2016200179B2 (en) | 2015-01-14 | 2020-09-17 | Stryker European Operations Holdings Llc | Spinal implant with porous and solid surfaces |
CA2917503A1 (en) | 2015-01-14 | 2016-07-14 | Stryker European Holdings I, Llc | Spinal implant with fluid delivery capabilities |
EP3064175B1 (en) * | 2015-03-03 | 2023-11-01 | SMed - TA/TD LLC | Orthopaedic implant with porous structural member |
CA2930123A1 (en) | 2015-05-18 | 2016-11-18 | Stryker European Holdings I, Llc | Partially resorbable implants and methods |
CN107397611A (zh) * | 2016-05-19 | 2017-11-28 | 重庆润泽医药有限公司 | 一种椎体间脊柱植入体 |
CN106473836A (zh) * | 2016-12-12 | 2017-03-08 | 运怡(北京)医疗器械有限公司 | 一种多孔peek界面钉 |
JP2020533070A (ja) | 2017-09-08 | 2020-11-19 | パイオニア サージカル テクノロジー インコーポレイテッド | 椎間インプラント、器具、及び方法 |
EP3459502A1 (en) | 2017-09-20 | 2019-03-27 | Stryker European Holdings I, LLC | Spinal implants |
USD907771S1 (en) | 2017-10-09 | 2021-01-12 | Pioneer Surgical Technology, Inc. | Intervertebral implant |
US11065126B2 (en) | 2018-08-09 | 2021-07-20 | Stryker European Operations Holdings Llc | Interbody implants and optimization features thereof |
US20220072205A1 (en) * | 2020-09-04 | 2022-03-10 | Phoenyx Spinal Technologies, Inc. | Dual material implant |
TWI779675B (zh) | 2021-06-18 | 2022-10-01 | 國立臺灣大學 | 椎間融合裝置 |
Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5192327A (en) * | 1991-03-22 | 1993-03-09 | Brantigan John W | Surgical prosthetic implant for vertebrae |
CN1122686A (zh) * | 1993-10-01 | 1996-05-22 | 艾科麦得公司 | 脊椎植入物 |
US5769897A (en) * | 1991-12-13 | 1998-06-23 | Haerle; Anton | Synthetic bone |
WO1998056319A1 (en) * | 1997-06-11 | 1998-12-17 | Sdgi Holdings, Inc. | Reinforced bone graft sustitutes |
US5865845A (en) * | 1996-03-05 | 1999-02-02 | Thalgott; John S. | Prosthetic intervertebral disc |
US5888222A (en) * | 1995-10-16 | 1999-03-30 | Sdgi Holding, Inc. | Intervertebral spacers |
WO2000066045A1 (en) * | 1999-05-05 | 2000-11-09 | Michelson Gary K | Spinal fusion implants with opposed locking screws |
CN1299252A (zh) * | 1998-03-02 | 2001-06-13 | 拜奥恩克斯移植有限公司 | 改进的生物可吸收的固定骨塞的植入物 |
WO2001049219A1 (en) * | 2000-01-06 | 2001-07-12 | Tutogen Medical Gmbh | Implant of bone matter |
US6270528B1 (en) * | 1998-08-06 | 2001-08-07 | Sdgi Holdings, Inc. | Composited intervertebral bone spacers |
WO2001068005A2 (en) * | 2000-03-14 | 2001-09-20 | Sdgi Holdings, Inc. | Vertebral implant for promoting arthrodesis of the spine |
US20010047208A1 (en) * | 1999-12-08 | 2001-11-29 | Michelson Gary K. | Spinal implant surface configuration |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2620890A1 (de) * | 1976-05-12 | 1977-11-17 | Battelle Institut E V | Knochenersatz-, knochenverbund- oder prothesenverankerungsmasse auf kalziumphosphatbasis |
JPS5654841A (en) * | 1979-10-08 | 1981-05-15 | Mitsubishi Mining & Cement Co | Bone broken portion and filler for void portion and method of treating bone of animal using said filler |
US4815454A (en) * | 1987-11-16 | 1989-03-28 | Dozier Jr John K | Apparatus and method for injecting bone cement |
DE3826915A1 (de) * | 1988-08-09 | 1990-02-15 | Henkel Kgaa | Neue werkstoffe fuer den knochenersatz und knochen- bzw. prothesenverbund |
DE4215137A1 (de) * | 1991-06-04 | 1992-12-10 | Man Ceramics Gmbh | Implantat fuer wirbelsaeulen |
DE4120325A1 (de) * | 1991-06-20 | 1992-12-24 | Merck Patent Gmbh | Implantatwerkstoff |
DE4219321A1 (de) * | 1992-06-12 | 1993-12-16 | Draenert Klaus | Polymergranulat und Verfahren zu seiner Herstellung |
FR2708461B1 (fr) * | 1993-08-06 | 1995-09-29 | Advanced Technical Fabrication | Implant intersomatique pour colonne vertébrale. |
US5425772A (en) * | 1993-09-20 | 1995-06-20 | Brantigan; John W. | Prosthetic implant for intervertebral spinal fusion |
DE69516279T2 (de) * | 1994-05-23 | 2000-08-10 | Sulzer Spine Tech Inc | Implantat zur intervertebralen fusion |
FR2727003B1 (fr) * | 1994-11-18 | 1997-04-18 | Euros Sa | Dispositif de stabilisation anterieure du rachis lombo-sacre |
EP1504732B1 (en) * | 1995-03-27 | 2007-05-23 | Warsaw Orthopedic, Inc. | Spinal fusion implant |
DE19541114A1 (de) * | 1995-10-26 | 1997-04-30 | Artos Med Produkte | Zwischenwirbelimplantat |
FR2742653B1 (fr) * | 1995-12-21 | 1998-02-27 | Colorado | Cage vertebrale intersomatique |
FR2743496B1 (fr) * | 1996-01-15 | 1998-04-10 | Univ Rennes | Composite macroporeux support de substance(s) medicamenteuse(s) utilisable comme materiau de reconstitution osseuse et procede d'elaboration |
DE19610715C1 (de) * | 1996-03-19 | 1997-06-26 | Axel Kirsch | Verfahren zum Herstellen eines Knochenersatzmaterials |
DE19614421C2 (de) * | 1996-04-12 | 1999-12-16 | Biovision Gmbh | Verfahren zur Herstellung eines biodegradierbaren Knochenersatz- und Implantatwerkstoffes und biodegradierbarer Knochenersatz- und Implantatwerkstoff |
FR2754170B1 (fr) * | 1996-10-03 | 1998-12-24 | Medinov Amp | Prothese d'arthrodese intersomatique vertebrale |
FR2758988B1 (fr) * | 1997-02-05 | 2000-01-21 | S H Ind | Procede d'elaboration de substituts osseux synthetiques d'architecture poreuse parfaitement maitrisee |
US6001100A (en) * | 1997-08-19 | 1999-12-14 | Bionx Implants Oy | Bone block fixation implant |
DE29901612U1 (de) * | 1998-01-23 | 1999-04-08 | Aesculap Ag & Co Kg | Zwischenwirbelimplantat |
EP0979638B1 (de) * | 1998-08-13 | 2002-12-04 | Erkan Dirik | Wirbelsäulen-Implantat |
US6099531A (en) * | 1998-08-20 | 2000-08-08 | Bonutti; Peter M. | Changing relationship between bones |
AU776806B2 (en) * | 1999-05-05 | 2004-09-23 | Warsaw Orthopedic, Inc. | Nested interbody spinal fusion implants |
DE29913200U1 (de) * | 1999-07-28 | 1999-09-23 | Tutogen Medical Gmbh | Implantat aus Knochenmaterial |
PT1250163E (pt) * | 2000-01-28 | 2005-04-29 | Dot Gmbh | Material de substituicao osseo reabsorvivel inorganico e metodo de producao |
US7169183B2 (en) * | 2000-03-14 | 2007-01-30 | Warsaw Orthopedic, Inc. | Vertebral implant for promoting arthrodesis of the spine |
US7226480B2 (en) * | 2000-08-15 | 2007-06-05 | Depuy Spine, Inc. | Disc prosthesis |
DE20015265U1 (de) * | 2000-09-01 | 2000-12-21 | Thull Roger | Inter-vertebrales Metallimplantat mit physiologischer Flexiblität in Belastungsrichtung |
DE10054857B4 (de) * | 2000-11-06 | 2005-02-17 | Bohmann, Anton, Dr.med., Dipl.-Ing. (FH) | System zur Herstellung von individuell formbarem Knochenersatz |
-
2002
- 2002-03-30 DE DE20205016U patent/DE20205016U1/de not_active Expired - Lifetime
-
2003
- 2003-01-16 US US10/508,024 patent/US7135042B2/en not_active Expired - Lifetime
- 2003-01-16 EP EP03700041A patent/EP1490001A1/de not_active Withdrawn
- 2003-01-16 MX MXPA04009547A patent/MXPA04009547A/es not_active Application Discontinuation
- 2003-01-16 RU RU2004131849/14A patent/RU2004131849A/ru not_active Application Discontinuation
- 2003-01-16 CN CNB038074761A patent/CN100428920C/zh not_active Expired - Lifetime
- 2003-01-16 NZ NZ535475A patent/NZ535475A/en not_active IP Right Cessation
- 2003-01-16 JP JP2003579706A patent/JP2005529634A/ja active Pending
- 2003-01-16 WO PCT/CH2003/000020 patent/WO2003082160A1/de active IP Right Grant
- 2003-01-16 IL IL16414903A patent/IL164149A0/xx unknown
- 2003-01-16 CA CA2480884A patent/CA2480884C/en not_active Expired - Fee Related
- 2003-01-16 AU AU2003258526A patent/AU2003258526B2/en not_active Ceased
- 2003-01-16 BR BR0308852-9A patent/BR0308852A/pt not_active Application Discontinuation
- 2003-01-16 KR KR10-2004-7015199A patent/KR20040105797A/ko not_active Application Discontinuation
- 2003-01-24 TW TW092101547A patent/TW200304368A/zh unknown
-
2004
- 2004-09-23 ZA ZA200407708A patent/ZA200407708B/en unknown
- 2004-10-26 CO CO04107584A patent/CO5611081A2/es active IP Right Grant
- 2004-10-29 NO NO20044685A patent/NO20044685L/no not_active Application Discontinuation
Patent Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5192327A (en) * | 1991-03-22 | 1993-03-09 | Brantigan John W | Surgical prosthetic implant for vertebrae |
US5769897A (en) * | 1991-12-13 | 1998-06-23 | Haerle; Anton | Synthetic bone |
CN1122686A (zh) * | 1993-10-01 | 1996-05-22 | 艾科麦得公司 | 脊椎植入物 |
US5888222A (en) * | 1995-10-16 | 1999-03-30 | Sdgi Holding, Inc. | Intervertebral spacers |
US5865845A (en) * | 1996-03-05 | 1999-02-02 | Thalgott; John S. | Prosthetic intervertebral disc |
WO1998056319A1 (en) * | 1997-06-11 | 1998-12-17 | Sdgi Holdings, Inc. | Reinforced bone graft sustitutes |
CN1299252A (zh) * | 1998-03-02 | 2001-06-13 | 拜奥恩克斯移植有限公司 | 改进的生物可吸收的固定骨塞的植入物 |
US6270528B1 (en) * | 1998-08-06 | 2001-08-07 | Sdgi Holdings, Inc. | Composited intervertebral bone spacers |
WO2000066045A1 (en) * | 1999-05-05 | 2000-11-09 | Michelson Gary K | Spinal fusion implants with opposed locking screws |
US20010047208A1 (en) * | 1999-12-08 | 2001-11-29 | Michelson Gary K. | Spinal implant surface configuration |
WO2001049219A1 (en) * | 2000-01-06 | 2001-07-12 | Tutogen Medical Gmbh | Implant of bone matter |
WO2001068005A2 (en) * | 2000-03-14 | 2001-09-20 | Sdgi Holdings, Inc. | Vertebral implant for promoting arthrodesis of the spine |
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TW200304368A (en) | 2003-10-01 |
IL164149A0 (en) | 2005-12-18 |
MXPA04009547A (es) | 2005-06-08 |
WO2003082160A1 (de) | 2003-10-09 |
CA2480884A1 (en) | 2003-10-09 |
US20050065604A1 (en) | 2005-03-24 |
BR0308852A (pt) | 2005-01-25 |
JP2005529634A (ja) | 2005-10-06 |
NO20044685L (no) | 2004-10-29 |
US7135042B2 (en) | 2006-11-14 |
CA2480884C (en) | 2010-08-03 |
ZA200407708B (en) | 2005-07-01 |
CO5611081A2 (es) | 2006-02-28 |
RU2004131849A (ru) | 2005-08-10 |
KR20040105797A (ko) | 2004-12-16 |
CN1642497A (zh) | 2005-07-20 |
EP1490001A1 (de) | 2004-12-29 |
AU2003258526B2 (en) | 2006-09-21 |
NZ535475A (en) | 2005-12-23 |
DE20205016U1 (de) | 2003-08-14 |
AU2003258526A1 (en) | 2003-10-13 |
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