CN100413520C

CN100413520C - Medicine for treating prostatitis

Info

Publication number: CN100413520C
Application number: CNB2006100122273A
Authority: CN
Inventors: 胡广德
Original assignee: Individual
Current assignee: Individual
Priority date: 2006-06-13
Filing date: 2006-06-13
Publication date: 2008-08-27
Anticipated expiration: 2026-06-13
Also published as: CN1895499A

Abstract

A Chinese medicine for treating non-bacterial prostatitis, chronic bacterial prostatitis and prostatoplasia is proportionally prepared from 10 Chinese-medicinal materials including cordyceps, yam, dandelion herb, pilose asiabell root, etc.

Description

The prostatitic medicine of a kind of treatment

Technical field

The present invention relates to a kind of medicine, the prostatitic medicine of promptly a kind of treatment.

Background technology

Prostatitis is that a kind of male reproductive system catches, clinical two kinds of bacterial prostatitis and the nonbacterial prostatitis of seeing more.Bacterial prostatitis is divided into acute bacterial prostatitis and chronic bacterial prostatitis again.How per urethram bacterial prostatitis retrograde infection or hematogenous infection causes that pathogenic bacterium mostly are blue formula negative bacillus of leather or pseudomonas, and staphylococcus, streptococcus, infusorian, sand holes chlamydia, mycoplasma, blastomyces, mycete etc.It is anxious that acute prostatitis shows as morbidity more, the heating fear of cold, urinate burn feeling is arranged, urgent micturition, dysurea, frequent micturition, the waist perineal position weighs down distending pain, and the rectal distention stimulation symptom is arranged, urethra can have the rheuminess thing, or dysuria is arranged, even urine retention occurs.Outbreaks of infection can cause spermatitis, epididymitis, septicemia.Chronic prostatitis is except urethral symptom and prostatorrhoea, often have on lumbosacral region, perineal position, scrotum portion, the pubis, groin etc. located acid and expanded uncomfortable, sexual dysfunctions such as also visible sexual impotence, premature ejaculation, seminal emission or painful ejaculation, and the doubt anxiety often arranged, feel depressed, have a sleepless night, psychoneurosis shape such as dizzy, unable, can and have or secondary iritis, arthritis, neuritis, myositis, complication such as sterile.Acute prostatitis adopts antimicrobial drugs such as bactrim, erythromycin, ampicillin, metronidazole more, chronic bacillary inflammation multiselect bactrim, erythromycin, doxycycline, acetylspiramycin, rifampicin etc.Because the barrier action of prostate glandular epithelium quasi-lipid film, many antibiotics are difficult to arrive affected part, and how undesirable therapeutic effect is.The nonbacterial prostatitis pathogenic factor is still indeterminate, may be with frequent erection anejaculation, coitus incompletus or long-distancely drive that to cause congestion of prostate relevant, the difficulty of cured substance is bigger.

Summary of the invention

The purpose of this invention is to provide a kind of medicine that prostatitis is had significant curative effect.

Above-mentioned purpose is realized by following technical scheme: get crude drug Cordyceps 1-3 part by weight, Rhizoma Dioscoreae 18-30 part, Herba Taraxaci 20-30 part, Cortex Moutan 8-15 part, Radix Codonopsis 25-30 part, Poria 20-25 part, Rhizoma Atractylodis Macrocephalae 15-20 part, Fructus Corni 15-20 part, Radix Aconiti Lateralis Preparata 10-15 part, Squama Manis 5-10 part is concocted patent medicine.

The medicine that adopts technique scheme to make has significant curative effect to prostatitis, and prostatic hyperplasia is also had therapeutical effect preferably.

The specific embodiment

Introduce two kinds of embodiment below.

First kind: get 2 parts of crude drug Cordyceps by weight, 24 parts of Rhizoma Dioscoreaes, 25 parts of Herba Taraxacis, 11 parts of Cortex Moutans, 28 parts of Radix Codonopsis, 22 parts of Poria, 18 parts of the Rhizoma Atractylodis Macrocephalaes, 17 parts of Fructus Corni, 13 parts of Radix Aconiti Lateralis Preparatas, 8 parts of Squama Manis are made powder with Cordyceps, with the Cordyceps powder mixing, make ball, diffusing, tablet after all the other each crude drug water boiling concentration.

Usage: the weight portion of above-mentioned raw materials medicine is changed in gram, then is daily dose, sooner or later each once, 10 days is a course of treatment, general medication 2-3 course of treatment.

Second kind: get 1 part of crude drug Cordyceps by weight, 30 parts of Rhizoma Dioscoreaes, 20 parts of Herba Taraxacis, 10 parts of Cortex Moutans, 30 parts of Radix Codonopsis, 20 parts of Poria, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Fructus Corni, 10 parts of Radix Aconiti Lateralis Preparatas, 6 parts of Squama Manis are made powder with Cordyceps, and all the other each liquid medicine are fried in shallow oil and are concentrated back and Cordyceps powder mixing.

Usage: the unit of weight of above-mentioned raw materials medicine then is a daily dose in gram, sooner or later each once, 10 days is a course of treatment, general medication 2-3 course of treatment.

Pharmacodynamic analysis: prostatitis is seen bacterial infection pathological changes and functional pathological changes more, and cause effect relation is often arranged between the two, is promptly driven in the wrong direction through urinary tract by malignant bacteria earlier and invades, and multiplies in body of gland and spreads unchecked, and produces toxin, causes tissue damaged to cause dysfunction.Clinical common behind antibiotic therapy antibacterial go out, but the case that symptom still continues is exactly the presentation of tissue damaged.Therefore, this medicine has adopted the crude drug of the antibacterial anti-inflammatory and two aspects of strengthening function.Wherein: Cordyceps contains cordycepic acid (C ₇H ¹²O ₆) and the Cordyceps element, having good antibacterial action, in vitro tests has proved all has inhibitory action to streptococcus, staphylococcus, anthrax bacillus, tulase etc.; Herba Taraxaci contains taraxacin and the black alcohol (C of Herba Taraxaci ₃₀H ₅₀O ₅), having antibacterial and detoxicating, the eliminating carbuncle eliminating stagnation is the medicine commonly used of acute mastitis, furunculosis; Cortex Moutan contains paeonol (C ₉H ₁₀O ₂), the former glycoside of Cortex Moutan, benzoic acid, the black alcohol of plant, tannin etc., have antibacterial action, experiment in vitro has stronger antibacterial action to Bacillus typhi, escherichia coli, staphylococcus aureus, Hemolytic streptococcus, streptococcus pneumoniae etc., and diphtheria corynebacterium is also had inhibitory action.Fructus Corni is a Fructus Corni, contains evonoside, gallic acid, tartaric acid, malic acid, V _AThe class material, antibacterial action is outstanding, and bacillus pyocyaneus, golden yellow staphylococcus and various skin tinea bacterium are all had inhibitory action; The first sheet has detumescence and apocenosis, the silt collateral dredging that looses, and is the medicine commonly used of ulcer sore pain, anemofrigid-damp arthralgia.Rhizoma Dioscoreae then contains Saponin, arginine, allantoic acid, choline, amylase, has QI invigorating strengthening the spleen, antidiarrheal eliminate the phlegm, the quench one's thirst effect of replenishing essence; Radix Codonopsis contains alkaloid, Saponin, protein, starch, V _B, V ₂Deng, but invigorating the spleen and replenishing QI, be good for the stomach and nourish blood, promote the production of body fluid and eliminate the phlegm; Poria promptly originates in the Poria in Yunnan, contains β-pachymose (C ₃₃H ₅₂O ₅), protein, fat, lecithin, histamine, choline, the black pure and mild potassium salt of Ergota etc., have diuresis, nourishing, abirritative effect and promoting diuresis to eliminate damp pathogen, the function of strengthening the spleen mind calming; The Rhizoma Atractylodis Macrocephalae contains atractylol (C ₁₅H ₂₄O), Rhizoma Atractylodis Macrocephalae ketone (C ₁₅H ₂₀O), V _AThe class material has invigorating the spleen and replenishing QI, dampness diuretic, promoting digestion and protecting liver, calm hidroschesis, the anticancer effect of nourishing; Radix Aconiti Lateralis Preparata contains aconitine (C ₃₄H ₄₇O ₁₁N), mesaconitine (C ₃₃H ₄₅O ₁₁N) and hypaconitine (C ₃₃H ₄₅O ₁₁N) alkaloid and non-alkaloid such as have the effect of heart tonifying, analgesia, antiinflammatory, excited hypophysis-interrenal system, are usually used in recuperating depleted YANG and rescuing the patient from collapse, dispersing cold for relieving pain, by the wind damp eliminating.As seen, the above-mentioned raw materials medicine had both been emphasized antibacterial and detoxicating, laid particular emphasis on nourishing conditioning again, and strengthening the taste hepatic and renal function for wanting, thereby prostatitis has been produced comprehensive function.Owing to strengthened organ function, particularly adopt promoting diuresis to eliminate damp pathogen, the component of strengthening the spleen mind calming, thereby the prostatic hyperplasia patient also had certain curative effect.

Experiment situation:, since 2000, under the support of medical departments such as Tongliao City's foundation hospital, respectively bacterial prostatitis and nonbacterial prostatitis have been carried out the clinical comparison experiment in order to confirm the therapeutic effect of this medicine.Experimental result is as follows:

Experiment 1: bacterial prostatitis clinical experiment

In line with the principle of voluntariness, according to rectal touch and microscopy standard, picked at random bacterial prostatitis patient 64 examples are divided into matched group and experimental group, each 32 example.Wherein, matched group acute patient 12 examples, chronic patients 20 examples.Experimental group acute patient 10 examples, chronic patients 22 examples.Matched group adopts conventional medicines such as bactrim, erythromycin, rifampicin, conventional therapy.Experimental group adopts this medicine, through 2-3 the course of treatment.Bacterial prostatitis obviously drops to effectively with the microscopy antibacterial, and nothing detects and transference cure is healing.It serves as effectively that nonbacterial prostatitis is obviously alleviated with symptom, and transference cure and nothing recurrence in six months are for curing.Its result is as follows:

Table 1 bacterial prostatitis treatment situation

The acute chronic effective healing of group example number is invalid

Experimental group 32 10 22 24 20 8

Matched group 32 12 20 29 17 3

The prostatitic treatment situation of table 2 acute bacterial

It is invalid that group example number is effectively cured

Experimental group 10 436

Matched group 12 10 72

The treatment situation of table 3 chronic bacterial prostatitis

It is invalid that group example number is effectively cured

Experimental group 22 20 17 2

Matched group 20 19 10 1

Experiment 2: nonbacterial prostatitis clinical experiment

Table 4

Group adds up to effectively healing invalid

Experimental group 32 28 20 4

Matched group 32 18 7 14

Experimental analysis:

Table 5 is put in order as following table by table 1

Group effective percentage (%) cure rate (%) inefficiency (%)

Experimental group 75 62 25

Matched group 91 53 9

Table 6 is put in order as following table by table 2

Group effective percentage (%) cure rate (%) inefficiency (%)

Experimental group 40 30 60

Matched group 83 58 17

Table 7 is put in order as following table by table 3

Group effective percentage (%) cure rate (%) inefficiency (%)

Experimental group 91 77 9

Matched group 95 50 5

Table 8 is put in order as following table by table 4

Group effective percentage (%) cure rate (%) inefficiency (%)

Experimental group 88 62 12

Matched group 56 22 44

Conclusion: as seen from Table 5, for bacterial prostatitis, the effective percentage of experimental group is starkly lower than matched group, and inefficiency is apparently higher than matched group, and, its cure rate but is higher than matched group.Thereby, still have certain application value.From table 6 and table 7 as can be seen, this medicine should not be adopted, and, this medicine can be considered to adopt, to improve cure rate for the patient of chronic bacterial prostatitis for the acute bacterial prostatitis.

By table 8 as seen, for nonbacterial prostatitis, effective percentage of this medicine and cure rate have significant difference all apparently higher than matched group, should advocate and use this medicine.

Claims

1. treat prostatitic medicine for one kind, it is characterized in that: this medicine is to be made by following bulk drugs: Cordyceps 1-3 part, Rhizoma Dioscoreae 18-30 part, Herba Taraxaci 20-30 part, Cortex Moutan 8-15 part, Radix Codonopsis 25-30 part, Poria 20-25 part, Rhizoma Atractylodis Macrocephalae 15-20 part, Fructus Corni 15-20 part, Radix Aconiti Lateralis Preparata 10-15 part, Squama Manis 5-10 part.

2. the prostatitic medicine of treatment according to claim 1, it is characterized in that: this medicine is to be made by following bulk drugs: 2 parts of Cordyceps, 24 parts of Rhizoma Dioscoreaes, 25 parts of Herba Taraxacis, 11 parts of Cortex Moutans, 28 parts of Radix Codonopsis, 22 parts of Poria, 18 parts of the Rhizoma Atractylodis Macrocephalaes, 17 parts of Fructus Corni, 13 parts of Radix Aconiti Lateralis Preparatas, 8 parts of Squama Manis.

3. the prostatitic medicine of treatment according to claim 1, it is characterized in that: this medicine is to be made by following bulk drugs: 1 part of Cordyceps, 30 parts of Rhizoma Dioscoreaes, 20 parts of Herba Taraxacis, 10 parts of Cortex Moutans, 30 parts of Radix Codonopsis, 20 parts of Poria, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Fructus Corni, 10 parts of Radix Aconiti Lateralis Preparatas, 6 parts of Squama Manis.