CN100398103C - 通过烟碱性受体激动剂和单胺能物质的联合作用治疗情感性精神障碍 - Google Patents

通过烟碱性受体激动剂和单胺能物质的联合作用治疗情感性精神障碍 Download PDF

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Publication number
CN100398103C
CN100398103C CNB018168035A CN01816803A CN100398103C CN 100398103 C CN100398103 C CN 100398103C CN B018168035 A CNB018168035 A CN B018168035A CN 01816803 A CN01816803 A CN 01816803A CN 100398103 C CN100398103 C CN 100398103C
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pyridyl
mixture
compound
chloro
bromo
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CN1635877A (zh
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G·M·奥尔森
D·彼得斯
E·O·尼尔森
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NTG Nordic Transport Group AS
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Neurosearch AS
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    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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CNB018168035A 2000-10-13 2001-10-10 通过烟碱性受体激动剂和单胺能物质的联合作用治疗情感性精神障碍 Expired - Fee Related CN100398103C (zh)

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DKPA200001535 2000-10-13
DKPA200001535 2000-10-13
US24214600P 2000-10-23 2000-10-23
US60/242,146 2000-10-23

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CN1635877A CN1635877A (zh) 2005-07-06
CN100398103C true CN100398103C (zh) 2008-07-02

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EP (2) EP1757600A2 (OSRAM)
JP (2) JP4312456B2 (OSRAM)
CN (1) CN100398103C (OSRAM)
AT (1) ATE334979T1 (OSRAM)
AU (2) AU2001295436B2 (OSRAM)
CA (1) CA2425638C (OSRAM)
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JP2002543070A (ja) * 1999-04-26 2002-12-17 ニューロサーチ、アクティーゼルスカブ ヘテロアリールジアザシクロアルカン類、その製造方法及びその使用方法
MXPA04010965A (es) 2002-05-07 2005-01-25 Neurosearch As Derivados de etinilo azaciclico novedoso.
MXPA04011206A (es) * 2002-05-15 2005-02-14 Abbott Lab Tratamiento de dolor neuropatico.
US7273872B2 (en) † 2002-12-06 2007-09-25 The Feinstein Institute For Medical Research Inhibition of inflammation using α 7 receptor-binding cholinergic agonists
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