CN100386097C - Medicine with quantitative antiendotoxic action - Google Patents
Medicine with quantitative antiendotoxic action Download PDFInfo
- Publication number
- CN100386097C CN100386097C CNB001077783A CN00107778A CN100386097C CN 100386097 C CN100386097 C CN 100386097C CN B001077783 A CNB001077783 A CN B001077783A CN 00107778 A CN00107778 A CN 00107778A CN 100386097 C CN100386097 C CN 100386097C
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- pure chinese
- medicine preparation
- radix
- endotoxin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003814 drug Substances 0.000 title claims abstract description 21
- 230000001986 anti-endotoxic effect Effects 0.000 title claims abstract description 9
- 229940079593 drug Drugs 0.000 title claims description 3
- 230000000694 effects Effects 0.000 claims abstract description 11
- 238000002360 preparation method Methods 0.000 claims abstract description 11
- 239000002775 capsule Substances 0.000 claims abstract description 7
- -1 sodium decanoyl acetaldehyde Chemical compound 0.000 claims abstract description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 6
- 241000628997 Flos Species 0.000 claims description 6
- 239000000706 filtrate Substances 0.000 claims description 6
- HPPWMWCITPGPKK-UHFFFAOYSA-M sodium;1-hydroxy-3-oxododecane-1-sulfonate Chemical compound [Na+].CCCCCCCCCC(=O)CC(O)S([O-])(=O)=O HPPWMWCITPGPKK-UHFFFAOYSA-M 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 239000003463 adsorbent Substances 0.000 claims description 3
- 238000009835 boiling Methods 0.000 claims description 3
- 239000003480 eluent Substances 0.000 claims description 3
- 238000010828 elution Methods 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 239000000843 powder Substances 0.000 claims description 3
- 238000003825 pressing Methods 0.000 claims description 3
- 239000011347 resin Substances 0.000 claims description 3
- 229920005989 resin Polymers 0.000 claims description 3
- 238000001694 spray drying Methods 0.000 claims description 3
- 239000002158 endotoxin Substances 0.000 abstract description 5
- 238000000034 method Methods 0.000 abstract description 4
- 206010061218 Inflammation Diseases 0.000 abstract description 3
- 230000004054 inflammatory process Effects 0.000 abstract description 3
- 238000002474 experimental method Methods 0.000 abstract description 2
- 241000205585 Aquilegia canadensis Species 0.000 abstract 1
- 241000196324 Embryophyta Species 0.000 abstract 1
- 241000555682 Forsythia x intermedia Species 0.000 abstract 1
- 244000170916 Paeonia officinalis Species 0.000 abstract 1
- 235000006484 Paeonia officinalis Nutrition 0.000 abstract 1
- 241000219061 Rheum Species 0.000 abstract 1
- 235000009411 Rheum rhabarbarum Nutrition 0.000 abstract 1
- 241000207929 Scutellaria Species 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 230000036737 immune function Effects 0.000 abstract 1
- 238000012856 packing Methods 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 230000035939 shock Effects 0.000 abstract 1
- 230000001954 sterilising effect Effects 0.000 abstract 1
- 238000004659 sterilization and disinfection Methods 0.000 abstract 1
- 238000010998 test method Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 description 2
- 230000010534 mechanism of action Effects 0.000 description 2
- 206010014824 Endotoxic shock Diseases 0.000 description 1
- 206010040070 Septic Shock Diseases 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000002346 endotoxic effect Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
Images
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The present invention relates to a pure Chinese medicine preparation which is a recipe of medicine with quantitative antiendotoxic action; 2727g of honeysuckle, 2727g of forsythia, 1364g of scutellaria, 11.36g of sodium decanoyl acetaldehyde, 1636g of red peony and 909g of rhubarb are made into a capsule. The present invention has the advantages of reasonable prescription and obvious therapeutic effects. The pure Chinese medicine preparation is a pure green packing plant preparation and has the advantages of small side effects, safety, reliability and techniques purification technology. Proved by an experiment, the pure Chinese medicine preparation has specific active components. The pure Chinese medicine preparation has the action mechanism of directly eliminating endotoxin and is breakthrough contribution to medicine history. The pure Chinese medicine preparation acts on the middle link of an inflammation reaction, takes effect quickly, avoids serious complicating diseases such as shock, DIC, MSOF, etc., induced by the increase of the endotoxin, and eliminates the effect of the endotoxin. The pure Chinese medicine preparation is verified by a scientific test method. The pure Chinese medicine preparation does not have medicine resistance performance and is non hormone medicine. The present invention adjusts the immunological function of an organism and enhances antiendotoxic sterilization efficacy.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, be used to remove toxins in human body.
Background technology
The tradition antibiotic be with kill or suppress pathogenic microorganism, eliminate the inflammation is its mechanism of action, often causes the release of bacterial endotoxin sample material to increase in this process.
Summary of the invention
Purpose of the present invention discloses a kind of medicine with anti-endotoxin effect, and reasonable recipe is evident in efficacy.
The invention provides a kind of medicine, make capsule by crude drug Flos Lonicerae 2727g, Fructus Forsythiae 2727g, Radix Scutellariae 1346g, Sodium Houttuyfonate 11.36g, Radix Paeoniae Rubra 1636g, Radix Et Rhizoma Rhei 909g with anti-endotoxin effect.
The invention provides a kind of medicine with anti-endotoxin effect, its preparation technology is: Flos Lonicerae, Fructus Forsythiae, Radix Paeoniae Rubra, Radix Scutellariae are decocted with water three times, and 1.5 hours for the first time, second and third time respectively was 1 hour, and collecting decoction filters; Radix Et Rhizoma Rhei adds boiling water to be fried in shallow oil three times, and each 10 minutes, merge three times decocting liquid, filter; Merge above filtrate, fine straining, filtrate is adsorbed through adsorbent resin, and 70% ethanol elution, eluent are concentrated into proportion 1.15, and spray drying adds the Sodium Houttuyfonate fine powder, mixing, dry-pressing is granulated, and packs 1000 capsules into promptly.
Good effect of the present invention: reasonable recipe, evident in efficacy.
Toxic and side effects is little, and is safe and reliable;
Directly eliminating endotoxin is its mechanism of action;
Act on intermediate link, the onset rapidly of inflammatory reaction;
Can avoid because of endotoxic shock, the severe complications such as DIC, MSOF that bring out that increase;
Eliminating endotoxic effect can be verified through the scientific experiments method;
Adjust body's immunity, improve antibiotic bactericidal potency.
Description of drawings
Fig. 1 is a process chart of the present invention
The specific embodiment
Embodiment
Flos Lonicerae 2727g, Fructus Forsythiae 2727g, Radix Scutellariae 1346g, Sodium Houttuyfonate 11.36g, Radix Paeoniae Rubra 1636g, Radix Et Rhizoma Rhei 909g make capsule.
Flos Lonicerae, Fructus Forsythiae, Radix Paeoniae Rubra, Radix Scutellariae are decocted with water three times, and 1.5 hours for the first time, second and third time respectively was 1 hour, and collecting decoction filters; Radix Et Rhizoma Rhei adds boiling water to be fried in shallow oil three times, and each 10 minutes, merge three times decocting liquid, filter; Merge above filtrate, fine straining, filtrate is adsorbed through adsorbent resin, and 70% ethanol elution, eluent are concentrated into proportion 1.15, and spray drying adds the Sodium Houttuyfonate fine powder, mixing, dry-pressing is granulated, and packs 1000 capsules into promptly.
Creativeness of the present invention is verified by clinical
Claims (2)
1. the medicine with anti-endotoxin effect is characterized in that: make capsule by crude drug Flos Lonicerae 2727g, Fructus Forsythiae 2727g, Radix Scutellariae 1346g, Sodium Houttuyfonate 11.36g, Radix Paeoniae Rubra 1636g, Radix Et Rhizoma Rhei 909g.
2. according to the described medicine with anti-endotoxin effect of claim 1, it is characterized in that: preparation technology is: Flos Lonicerae, Fructus Forsythiae, Radix Paeoniae Rubra, Radix Scutellariae are decocted with water three times, and 1.5 hours for the first time, second and third time respectively was 1 hour, and collecting decoction filters; Radix Et Rhizoma Rhei adds boiling water to be fried in shallow oil three times, and each 10 minutes, merge three times decocting liquid, filter; Merge above filtrate, fine straining, filtrate is adsorbed through adsorbent resin, and 70% ethanol elution, eluent are concentrated into proportion 1.15, and spray drying adds the Sodium Houttuyfonate fine powder, mixing, dry-pressing is granulated, and packs 1000 capsules into promptly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB001077783A CN100386097C (en) | 2000-05-26 | 2000-05-26 | Medicine with quantitative antiendotoxic action |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB001077783A CN100386097C (en) | 2000-05-26 | 2000-05-26 | Medicine with quantitative antiendotoxic action |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1325692A CN1325692A (en) | 2001-12-12 |
| CN100386097C true CN100386097C (en) | 2008-05-07 |
Family
ID=4578935
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB001077783A Expired - Lifetime CN100386097C (en) | 2000-05-26 | 2000-05-26 | Medicine with quantitative antiendotoxic action |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100386097C (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1954818B (en) * | 2005-10-25 | 2010-04-28 | 崔乃杰 | Application of phillyrin in preparation for treating endotoxemia |
| CN103893290A (en) * | 2012-12-28 | 2014-07-02 | 四川省中医药科学院 | Pharmaceutical composition of endotoxin antagonist and preparation method thereof |
| CN110522880A (en) * | 2018-05-24 | 2019-12-03 | 河南炎黄生物工程有限公司 | A kind of Chinese medicine composition for preventing and treating laying hen mycotoxicosis, Chinese medicine microecological preparation and preparation method thereof |
-
2000
- 2000-05-26 CN CNB001077783A patent/CN100386097C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CN1325692A (en) | 2001-12-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN113521232B (en) | A Chinese medicinal composition containing Atractylodis rhizoma | |
| CN100386097C (en) | Medicine with quantitative antiendotoxic action | |
| Jakeli et al. | Biodiversity of Medicinal Plants of wild flora in Ajara-South Colchis and their usage in folk medicine | |
| CN110693997A (en) | Preparation for removing putrefaction and promoting granulation of scald and burn and preparation method thereof | |
| CN101983689B (en) | Drug for treating prostatitis and preparation method thereof | |
| CN101485701B (en) | Method for preparing total polyphenol of Loropetalum chinense (R. Br.) Oliver for treating burn and scald | |
| CN102293819B (en) | Tea saponin vagina-protecting lotion | |
| CN1227022C (en) | Capsule for treating epidemic parotitis | |
| CN101391044A (en) | External traditional Chinese medicine for treating zoster, herpes simplex or the other viral disease and preparation method thereof | |
| CN101987159B (en) | Medicine for treating erysipelas and preparation method thereof | |
| CN102309626A (en) | Traditional Chinese medicine prescription for treating postpartum fever | |
| CN102895386B (en) | Method for performing extraction on angelica dahurica, common cnidium fruit, Chinese red pepper and elecampane inula root and pharmaceutical application | |
| CN100418551C (en) | Ready prepared chinese medicine 'erjingling' drops for treating tympanitis and its preparation method | |
| CN109078115A (en) | A kind of Chinese materia medica preparation and preparation method thereof for hemorrhage of digestive tract | |
| CN1164318C (en) | Capsule for treating gynaecological inflammation | |
| CN103610928B (en) | A kind of Chinese medicine for the treatment of anaphy lactoid purpura nephritis | |
| CN101972388B (en) | Extraction method of smilax glabra total glycoside extractive | |
| CN100446786C (en) | Technique for producing extract product of mulberry bark | |
| CN105147821A (en) | Traditional Chinese medicine composition used for regulating endocrine function and preparation method | |
| CN1194732C (en) | Chinese herbal medicine for treating coronary heart disease and angina pectoris and its prepn | |
| CN101322784B (en) | Medicament with stomach-regulating and antidiarrheal efficacy and producing method thereof | |
| CN101147792B (en) | Method for preparing capsule for treating hepatitis B, clearing heat and antitoxic | |
| CN113440546A (en) | Acanthopanax senticosus total saponin, extraction method and application | |
| CN104147211A (en) | Medicine for treating gynecologic inflammation | |
| CN1486723A (en) | Menoxenia treating Chinese medicine |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| ASS | Succession or assignment of patent right |
Owner name: SHENYANG FEILONG PHARMACEUTICAL CO., LTD. Free format text: FORMER OWNER: JIANG WEI Effective date: 20060224 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20060224 Address after: 110166, 25, Changbai street, Heping District, Liaoning, Shenyang Applicant after: Shenyang Feilong Pharmaceutical Co., Ltd. Address before: 110166, 25, Changbai street, Heping District, Liaoning, Shenyang Applicant before: Jiang Wei |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: JIANG WEI Free format text: FORMER OWNER: SHENYANG FEILONG PHARMACEUTICAL CO., LTD. Effective date: 20080523 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20080523 Address after: Hunnan New District in Shenyang city of Liaoning Province Road No. 9, block A 203 Patentee after: Jiang Wei Address before: Hunnan New District in Shenyang city of Liaoning Province Road No. 9, block A 203 Patentee before: Shenyang Feilong Pharmaceutical Co., Ltd. |
|
| ASS | Succession or assignment of patent right |
Owner name: SHENYANG FEILONG PHARMACEUTICAL CO., LTD. Free format text: FORMER OWNER: JIANG WEI Effective date: 20140207 |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 110179 SHENYANG, LIAONING PROVINCE TO: 110300 SHENYANG, LIAONING PROVINCE |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20140207 Address after: 110300 Xinmin Industrial Zone, Liaoning Patentee after: Shenyang Feilong Pharmaceutical Co., Ltd. Address before: Hunnan New District Road Shenyang city Liaoning province 110179 No. 9 A block 203 Patentee before: Jiang Wei |
|
| TR01 | Transfer of patent right | ||
| CX01 | Expiry of patent term |
Granted publication date: 20080507 |
|
| CX01 | Expiry of patent term |