CN100386084C

CN100386084C - Health tooth paste composition

Info

Publication number: CN100386084C
Application number: CNB2005100336371A
Authority: CN
Inventors: 黄恒燊
Original assignee: Individual
Current assignee: Individual
Priority date: 2005-03-11
Filing date: 2005-03-11
Publication date: 2008-05-07
Anticipated expiration: 2025-03-11
Also published as: CN1682685A

Abstract

The present invention relates to a health toothpaste composition which comprises chitosan and hippophae rhamnoides extract. The health toothpaste composition of the present invention can effectively prevent and treat oral diseases, such as tooth decay, paradontal ulcer, halitosis, etc.

Description

Health tooth paste composition

Technical field

The present invention relates to a kind of composition of toothpaste, it is that a kind of can control effectively produces dental caries and prevent dental caries and possess the health-care toothpaste that the prevention periodontal festers, alleviates effects such as halitosis.

Background technology

Dental caries is one of the department of stomatology two big diseases, and its sickness rate is more than 50%, some area, and up to 70～90%, the middle-aged and elderly people cervical caries is also very serious as the sick rate of city hair of children at school age.For dental caries should be the important channel of treatment and caries prevention in early stage control of dental caries morbidity and elimination dental caries to put prevention first.

Along with the quickening of urban life rhythm, the personage that especially goes to work, living pressure often makes them have no time to attend to the health of oneself, suffers from various occupation disease easily, and listless when causing going to work, dispirited, work efficiency is low.If can in toothpaste, add nutritional labeling, when brushing teeth, supplement the nutrients, improved health unconsciously, this not only brushed teeth but also the toothpaste of body-building yet there are no all reports.

Chinese patent has disclosed a kind of anticariogenic dentifrice composition No. 97114612.8, and it mainly is to add a kind of containing to have added polyacrylic xylitol in formulation of tooth-paste.But because the time of staying of xylitol in the oral cavity in the toothpaste is shorter, can not give full play to the effect of its preventing decayed tooth, and xylitol is more single to the health-care effect of tooth, for other odontopathy, as periodontitis, halitosis etc., just can't realize the health-care effect that prevents or eliminate.

Summary of the invention

For the health-care toothpaste that overcomes prior art effectively preventing decayed tooth, prevention periodontal fester, alleviate effect such as halitosis and a kind of Neng You Xiao is provided anti-and treatment oral disease, as dental caries, periodontal fester, the health tooth paste composition of halitosis etc.

For solving the problems of the technologies described above, technical scheme of the present invention is, a kind of health tooth paste composition, it contains average molecular mass and is not higher than 10000 chitosan and Fructus Hippophae extract, the content of described chitosan is 0.5～10% weight, the content of described Fructus Hippophae extract is in 0.2～5% weight, Fructus Hippophae extract comprises a kind of in Fructus Hippophae concentrated juice and the Oleum Hippophae at least, also comprising of toothpaste combination: by the basis that abrasivus, wetting agent, emulsifying agent, thickening agent, sweeting agent, flavoring agent and water are formed, the percetage by weight of described fundamental component is:

Abrasivus 30～60%

Wetting agent 10～30%

Emulsifying agent 1～5%

Thickening agent 0.2～5%

Sweeting agent 0.1～2%

Flavoring agent 0.5～2%

Water 15～40%

Abrasivus is a dalcium biphosphate, and wetting agent is a sorbitol, and emulsifying agent is a sodium lauryl sulfate, and thickening agent is a sodium carboxymethyl cellulose, and sweeting agent is an xylitol, and flavoring agent is a spice, and institute's water is a deionized water.

The invention has the beneficial effects as follows:health tooth paste composition of the present invention is because of containing chitosan, so Neng You Xiao Di is anti-and the treatment oral disease, as dental caries, periodontal fester, halitosis etc.

Health-care toothpaste of the present invention adds nutritional labeling because also contain Fructus Hippophae extract in toothpaste, supplement the nutrients when brushing teeth, and has improved health unconsciously.

The specific embodiment

Health tooth paste composition of the present invention is a kind of health tooth paste composition of matters of containing biological activities, adds bioactive ingredients by the ordinary toothpaste composition and makes.This active component can be divided into active animal composition and active components of plants, and wherein a kind of in the active animal composition is chitosan, and the sticking of used chitosan all is not higher than 10000, and content is 0.5～10% of gross weight.

Active components of plants is a Fructus Hippophae extract, and this Fructus Hippophae extract comprises Fructus Hippophae concentrated juice and Oleum Hippophae at least.The content of used Fructus Hippophae extract is in 0.2～5% weight.

The basis and the weight percentage of used ordinary toothpaste are as follows, but are not limited thereto:

Abrasivus-dalcium biphosphate 30～60%

Wetting agent-sorbitol 10～30%

Emulsifying agent-sodium lauryl sulfate 1～5%

Thickening agent-sodium carboxymethyl cellulose 0.2～5%

Sweeting agent-xylitol 0.1～2%

Flavoring agent-spice 0.5～2%

Deionized water 15～40%

The main cause that produces dental caries is that Streptococcus mutans sticks the formation bacterial plaque at facing, and bacterial plaque is to cause the necessary initiation factor of dental caries, is the important means of preventing and treating dental caries in sticking of facing so prevent antibacterial.Chitosan has antibacterial activity to the tooth fungus, can reduce the ability of sticking of Streptococcus mutans and stick intensity, and then prevent the formation of bacterial plaque.Another mechanism of chitosan energy caries prevention is the pH value that it can change environment.As everyone knows, pH value reduces and can cause that dental enamel solubility increases.In PH4～7 scopes, 1 unit of the every reduction of pH value, the dissolubility of hydroxyapatite can increase by 7 times.Because the existence form of phosphate radical depends on the pH value of solution, PH reduces, more PO ₄ ^3-Become HPO ₄ ^2-And H ₂PO ₄ ^-Thereby, quicken the dissolving of hydroxyapatite; PH value raises, and calcium hydrogen phosphate becomes the high apatite of Ca/P ratio, finally becomes hydroxyapatite.At bacterial plaque-enamel interface, the dissolving of constantly carrying out apatite along with the variation of pH value deposits again.If the pH value long term maintenance at bacterial plaque-enamel interface, is dissolved just completely reversibility no longer of deposition process low-level again, and causes permanent the losing from enamel of calcium, phosphorus gradually.Beginning, the decalcification zone forms under the top layer of complete relatively electron density, shows as the Chalk speckle clinically, and is last, top layer irregular, permeability is destroyed, and antibacterial is invaded, and more bacterial plaque forms, cause more serious acid attack, final enamel destroys, and forms cavity.Chitosan has certain cushioning effect to the environment pH value, and the pH value of sour environment that can raise is so play preventive effect to dental caries.In addition, chitosan can also prevent periodontal to fester, alleviate halitosis.

Fructus Hippophae is commonly called as the vinegar willow, and the acid thorn belongs to Elaeangnaceae, machaka or dungarunga.Measure according to the nutritionist chemical examination, except that containing rich in protein, fat and carbohydrate, also contain the multivitamin and the mineral of needed by human in the Fructus Hippophae.The content of vitamin C ascorbic acid, E Vitamin E, A carotin, K wherein almost occupies the hat of all fruit and vegerable.Contain 18 seed amino acids such as aspartic acid, glutamic acid, proline, phenylalanine, threonine, tryptophan, lysine, leucine, isoleucine in the sea buckthorn fruit.Contain trace element more than 24 kinds such as phosphorus, ferrum, magnesium, manganese, potassium, calcium, boron, silicon, copper in the Fructus Hippophae.Oleum Hippophae is a fatty glyceride, the mixture of 18 kinds of fat acids such as Palmic acid, oleic acid, linoleic acid, linolenic acid is arranged, and major part is a unsaturated fatty acid, very easily is absorbed by the body, and can reduce fat sterin and triglyceride in the blood, can prevent and treat atherosclerosis and coronary heart disease effectively.With the Fructus Hippophae is the articles for use that primary raw material is made, and function such as promote the production of body fluid, refresh oneself, help that gas is invigorated blood circulation, helped digestion is arranged, and can strengthen body to be healthy and strong life lengthening, and flavoursome uniqueness, characteristics such as fragrance is good to eat, and the grown-ups and children is all suitable.

The toothpaste that provides of the present invention adds chitosan by the ordinary toothpaste composition and Fructus Hippophae extract makes, not only preventing decayed tooth, prevention periodontal fester, alleviate halitosis effectively, and in toothpaste, add nutritional labeling, when brushing teeth, supplement the nutrients, improved health unconsciously.

Example one (L1) and comparison example 1～3 thereof (toothpaste of DBL1～DBL3) is formed as table 1, and the unit of each component is a % weight:

Table 1

	L1	DBL1	DBL2	DBL3
	L1	DBL1	DBL2	DBL3	Dalcium biphosphate	50	50	50	50
Sorbitol	20	20	20	20	Dalcium biphosphate	50	50	50	50
Sorbitol	20	20	20	20	Sodium lauryl sulfate	2.0	2.0	2.0	2.0
Sodium carboxymethyl cellulose	0.8	0.8	0.8	0.8	Sodium lauryl sulfate	2.0	2.0	2.0	2.0
Sodium carboxymethyl cellulose	0.8	0.8	0.8	0.8	Xylitol	0.5	0.5	0.5	0.5
Spice	0.5	0.5	0.5	0.5	Xylitol	0.5	0.5	0.5	0.5
Spice	0.5	0.5	0.5	0.5	Chitosan	2.0	2.0	-	-
The Fructus Hippophae concentrated juice	1.0	-	1.0	-	Chitosan	2.0	2.0	-	-
The Fructus Hippophae concentrated juice	1.0	-	1.0	-	Oleum Hippophae	1.5	-	1.5	-

Deionized water (surplus)

21.7

24.2

23.7

26.2

28 oral pathology patients are equally divided into four groups, make use-case one (L1) and comparison example 1～3 thereof (toothpaste of DBL1～DBL3) 2 months respectively.Use is the result show: a group of patient's dental caries, periodontal of the toothpaste of use-case one is festered, symptom such as halitosis eliminates substantially, and health and mental attitude thereof are clearly better; Symptoms such as one group of patient's of Comparative Examples one oral disease such as dental caries, periodontal fester, halitosis are eliminated substantially; One group of patient's of Comparative Examples two oral disease does not have obvious improvement, but its health and mental attitude thereof are clearly better; And one group of patient's of Comparative Examples three oral disease and health thereof and mental attitude thereof all do not have obvious improvement.

The formulation of tooth-paste of other example sees Table 2, and the unit of each component is a % weight:

Table 2

40 oral pathology patients are equally divided into eight groups, use the toothpaste of prescription one to eight respectively, use 2 months continuously after, each is organized, and symptoms such as patient's dental caries, periodontal are festered, halitosis are eliminated substantially, and health and mental attitude thereof are clearly better.

Claims

1. health tooth paste composition, it contains average molecular mass and is not higher than 10000 chitosan and Fructus Hippophae extract, the content of described chitosan is 0.5～10% weight, the content of described Fructus Hippophae extract is in 0.2～5% weight, described Fructus Hippophae extract comprises a kind of in Fructus Hippophae concentrated juice and the Oleum Hippophae at least, described dentifrice composition also comprises: by the basis that abrasivus, wetting agent, emulsifying agent, thickening agent, sweeting agent, flavoring agent and water are formed, the percetage by weight of described fundamental component is: