CN100379427C - Tablet auxiliary product for increase of body immunological competence - Google Patents
Tablet auxiliary product for increase of body immunological competence Download PDFInfo
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- CN100379427C CN100379427C CNB2005101259993A CN200510125999A CN100379427C CN 100379427 C CN100379427 C CN 100379427C CN B2005101259993 A CNB2005101259993 A CN B2005101259993A CN 200510125999 A CN200510125999 A CN 200510125999A CN 100379427 C CN100379427 C CN 100379427C
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Abstract
The present invention relates to a tablet auxiliary product for increasing the immunological competence of the human body. The major raw materials of the product are as follows: 15 to 30% of lentinan powder, 3 to 7% of grifolan powder, 3 to 7% of morel polysaccharide powder, 10 to 20% of lycium barbarum polysaccharide powder, 0.1 to 0.8% of vitamin B complex and 10 to 20% of oligo-xylose; the auxiliary materials are 58.6 to 14.3% of amylum and 0.3 to 0.9% of magnesium stearate, wherein the fungi polysaccharides in the present invention are all made with a biological extraction method, and the polysaccharide content of the fungi polysaccharides is equal to or more than 30%. The fungus polysaccharide powder extracted with biological method reserves the nutrients and the effective components inside the fungus polysaccharide powder of the composition to the maximum, and the products taking the polysaccharide powder as the major raw materials can uniformly replenish various nutrients and have the function of assisting to increase the immunological competence of the human body.
Description
Technical field:
The present invention relates to a kind of employing lentinan powder, grifolan powder, Morchella esculenta (L.) Pers polysaccharide powder, lycium barbarum polysaccharide powder, compound vitamin, oligomeric xylose is a primary raw material, auxiliary with starch and magnesium stearate, through mix, technology such as system granule, drying, tabletting and make have an auxiliary tablet product that improves body immunity.
Background technology:
1. lentinan powder
Lentinus Edodes is that the traditional famous food of China has bacterium, in the world artificial domesticating cultivation the earliest.Lentinus Edodes is nutritious, and delicious flavour is regarded as " king in the mushroom ".Contain protein 1 8.64% in the dried thin mushroom, fat 4.8%, carbohydrate 71%, in ten several amino acids that Lentinus Edodes contains, the aminoacid that 7 kinds of needed by human such as isoleucine, lysine, phenylalanine, methionine, threonine, valine are arranged also contains vitamin D, B1, B2, PP and mineral salt and crude fibre etc.In the majority with hemicellulose in the carbohydrate in the Lentinus Edodes, main component is mannitol, trehalose and bacterium sugar, glucose, pentosan, methylpentosan etc., and these polysaccharide also are the main components in the lentinan powder.The health care of Lentinus Edodes is worth as follows:
1) it is very high to contain unsaturated fatty acid in the Lentinus Edodes, also contains the ergosterol and the fungisterol of a large amount of changed into vitamin D, for strengthening anti-disease and preventing cold and controlling preface good result is arranged.
2) often edible for want of vitamin D and the serium inorganic phosphorus that causes, rickets that the blood calcium dysbolismus causes are useful to prevention human body, particularly baby, can prevent various mucosas of human body and dermatitis disease.
3) from Lentinus Edodes, also isolate serum cholesterol-lowering composition (C8H1104N5, C9H1103N5).
4) contain a large amount of potassium salt and other mineral element in the Lentinus Edodes ash, be regarded as the ultimate food that prevents that acidic food is poisoned.
2. grifolan powder
Grifola frondosa has another name called hen of the woods [Polyporus frondosus], is commonly called as YUNTAN, and Japan's person dance is fine and soft, is a kind of famous and precious food, medicinal fungus newly developed.As a kind of high-class healthy food, be in fashion North America and Japanese market in recent years.Because of its outstanding nutrition and medical value, just causing people's extensive concern.
The Grifola Frondosa sporophore meat is tender and crisp, delicious in taste, fragrance is unique, nutrition-allocated proportion is reasonable, essential amino acid content height, and vitamin and content of mineral substances are abundant.100 gram Grifola frondosa dry products contain protein 22.75 grams after tested, aminoacid 23.58 grams (amino acid content doubles than Lentinus Edodes).And contain vitamin C, B1, B2 and organic selenium.According to the expertise Grifola frondosa six big medical care effects are arranged:
1) anticancer, oral cancer suppressing ratio reaches 86.3%;
2) defying age promotes gonad function;
3) prevent and treat diabetes;
4) suppress fat, the two-ways regulation blood pressure can be treated diseases such as arteriosclerosis, cerebral thrombosis;
5) oral beauty treatment and skin care delay senile plaque and occur;
6) stimulating appetite promotes growth, improves immunity, memory reinforcing.
Therefore, it is a kind of good edible fungus, is described as " edible fungi prince ".
American National cancer research institute just confirms that as far back as 1992 the extract of Grifola frondosa has the effect of opposing HIV (human immunodeficiency virus) (Human Immunodeficiency Virus).Doctor Nan Bohongming of Japan finds also that except that finding that in experiment Grifola frondosa has the effect of anti-HIV Grifola frondosa is also effective in cure to breast carcinoma, pulmonary carcinoma, hepatocarcinoma; Also can improve all untoward reaction that the chemotherapy of tumor is brought, as lack appetite, vomiting, feel sick, alopecia and leukopenia or the like; But alleviating pain also.In addition, research confirms that also Grifola frondosa has following several effect simultaneously:
1) reduces insulin resistant, strengthen the sensitivity of human body, help blood sugar control insulin;
2) suppressing adipose cell piles up;
3) bring high blood pressure down;
4) enhancing immunity.
3, Morchella esculenta (L.) Pers polysaccharide powder
Global now edible fungus has 2000 kinds, and Morchella esculenta (L.) Pers is one of wherein extremely famous and precious strain, because of extremely gaining the name as Gaster caprae seu Ovis on the cap surface.Morchella esculenta (L.) Pers contains protein 22.1%, fat 3.8%, polysaccharide 16.3%; And the unsaturated fatty acid in the fat is 5 to 3 with the ratio of satisfied fatty acid.Linoleic acid to the human body beneficial accounts for 56% of fatty acid total amount.The necessary aminoacid of human body is complete, and its content is 5.5 times of Lentinus Edodes, 5 times of Hericium erinaceus (Bull. Ex Fr.) Pers..Also contain the necessary elements of human body such as abundant potassium, phosphorus, ferrum, magnesium, zinc and selenium.Wherein the content of potassium, phosphorus is respectively 4 times and 2 times of Cordyceps, and zinc content is 9 times of Cordyceps.Selenium then can change carcinogenic metabolism direction and antioxidation, thereby Morchella esculenta (L.) Pers is described as " anticancer star ".
The health care of Morchella esculenta (L.) Pers is worth abroad and early is identified, and by U.S. food and medicine administrative organ FDA authentication, has obtained legal sale status, thus many countries such as rapid fashionable West Europe.On in November, 1999 Jiangsu " 99 Morchella esculenta (L.) Perss development and use seminar ".20 multidigit combination of Chinese and Western medicine experts of participant have carried out the composition demonstration to the nutritional labeling of Morchella esculenta (L.) Pers, consistently think that edible Morchella esculenta (L.) Pers has comprehensive health care function to human body, very significant effect is arranged at aspects such as fully improving human body comprehensive immunity, all kinds of fatigue syndrome of opposing.Easier being absorbed by the body of Morchella esculenta (L.) Pers after ultra micro is handled, it will benefit the people with its natural pure, remarkable comprehensively health care.
4, lycium barbarum polysaccharide powder
Fructus Lycii is the traditional rare Chinese medicine of China, have " red treasured " laudatory title, is rich in vegetable polysaccharides, protein, vitamins and other nutritious components.The main effect of Fructus Lycii is a nourishing the liver and kidney, replenishing vital essence to improve eyesight; Be used for chronic consumptive disease damage of essence, soreness of waist and knee joint; Vertigo and tinnitus, thirsty, the blood deficiency and yellow complexion of interior-heat Xiao, blurred vision is not clear.Successive dynasties expert in health preserving, physician value the tonic effect of Fructus Lycii very much.In Shennong's Herbal, just point out: obey hard muscles and bones for a long time; " Mingyi Bielu " meaning Fructus Lycii is good at " nourishing the essence and strengthening QI "; " Treatise on Dietetic Therapy " also puts down in writing Fructus Lycii " the beneficial people of energy removes asthenia ".Fructus Lycii is not only praised highly by ancient Chinese medicine doctor and dietetic therapy scholar in the effect aspect nourishing the liver and kidney, the replenishing vital essence to improve eyesight.
Lycium barbarum polysaccharide in the Fructus Lycii is its important active ingredient, the content of polysaccharide is different and different with the place of production in the Fructus Lycii, wherein the polyoses content in Inner Mongol, the lycium barbarum is the highest, reach 8.2%, Fructus Lycii polysaccharide (lbp) is made up of six kinds of monosaccharide ara, clc, gal, man, xyl and rha, can improve people's immunologic function, promote body to produce the nk-killer cell, and improve its activity, can play antivirus action indirectly by the human body immunity improving function, positive role is played in the prevention and the treatment of malignant tumor, acquired immune deficiency syndrome (AIDS).
Lycium barbarum polysaccharide be from Fructus Lycii, extract and a kind of water soluble polysaccharide.Clearly this polysaccharide is a proteoglycan, and molecular weight is 22～25kD, is become to be grouped into by arabinose, glucose, galactose, mannose, xylose, 6 kinds of monosaccharide of rhamnose, and detailed structural analysis is still in process.Show that after deliberation lycium barbarum polysaccharide is the main active that Fructus Lycii is regulated immunity, slow down aging, its prevention to malignant tumor, acquired immune deficiency syndrome (AIDS) also can be played positive role with treatment.It can improve symptoms such as old people's fatiguability, inappetence and blurred vision in addition, and has blood fat reducing, anti-fatty liver, antitumor, the anti-ageing effect of waiting for a long time.
5, oligomeric xylose
Oligomeric xylose has important biological function.Mainly show:
A) reduce in the generation human body body of poisonous tunning and bacterial enzyme thereof and in vitro the feces culture experiment show, take in oligomeric xylose after 3 weeks, can reduce the product of the noxious bacteria enzyme of 44.6% poisonous tunning and 40.9% in the body.
B) suppress pathogen and diarrhoea: oligomeric xylose has stronger absorption affinity to pathogen, but can both be adsorbed onto on the oligomeric xylose as escherichia coli, Salmonella, pneumonia thunder uncle Salmonella etc.
Because oligomeric xylose is not degraded by the digestive enzyme in the intestinal, the pathogen that portability adheres to excretes by intestinal, thereby wards off disease cluster from intestinal, reaches to prevent the diarrheal purpose.
C) prevent constipation: bacillus bifidus utilizes oligomeric xylose, produces a large amount of short-chain fatty acid, can stimulate intestinal peristalsis promoting, increases the feces wettability and keeps certain osmotic pressure, thereby prevent the generation of constipation.
D) the liver protecting function: take in oligomeric xylose, can reduce toxic metabolite and form, reduce the burden that liver divides toxolysin greatly.
E) reduce serum cholesterol: take in oligomeric xylose, continue 2 thoughtful 3 months, the total serum cholesterol can reduce by 20～50dl, also can improve the ratio that women's serum middle-high density lipoprotein cholesterol accounts for T-CHOL.
F) test that brings high blood pressure down shows, after 46 hypercalcinuria patients took in oligomeric xylose and continued for 5 weeks, its diastole flattened the 799.8pa (6mmHg) that all descended.Studies show that the height that a people's diastole is pressed is tangible negative correlativing relation with the ratio that the bacillus bifidus in its feces accounts for total bacteria count.
G) the enhancing body a large amount of experimental studies of power of exempting from service show, bacillus bifidus a large amount of breedings in intestinal can be played antitumaous effect.This antitumaous effect is given the credit to cell, cell wall constituent and the exocytosis thing of bacillus bifidus, and immunity of organisms is improved.
H) have in the excellent compatibility food a small amount of oligomeric xylose of interpolation and just can embody health-care effect.When oligomeric xylose and calcium are taken in simultaneously, not only can not influence the absorption of body to calcium, can play a driving role on the contrary.Result of the test shows: absorb 2% oligomeric xylose aqueous solution arbitrarily, body has improved 21% to the retention rate of calcium after 7 days.
I) belong to the sugariness of hanging down the intensity sweeteners oligomeric xylose and be about 40% of sucrose, and have thermostability and anti-crystallinity, so can be used as food improver.Sweeting agents such as its alternative Saccharum Sinensis Roxb. are widely used in the products such as beverage, confection, milk product, cold drink, flavoring agent and functional food.
J) can impel body to generate the multiple nutrients material and comprise vitamin B1, B2, B6, B12, nicotinic acid and folic acid.
K) prevent dental caries, suppress the oral cavity pathogenic bacteria grow dental caries since oral microorganism particularly the streptococcus erosion cause.Oligomeric xylose is not the suitable effect substrate of these oral microorganisms, therefore can not cause dental caries.
At present, polyoses such as many Lentinus Edodess, Fructus Lycii, Grifola frondosa, Morchella esculenta (L.) Pers adopt single or the small amount of matter composition mostly on the market, and the effect that is risen is single relatively.
Summary of the invention:
The objective of the invention is with lentinan powder, grifolan powder, Morchella esculenta (L.) Pers polysaccharide powder, lycium barbarum polysaccharide powder, compound vitamin, oligomeric xylose etc. is primary raw material, through the science compatibility, give full play to its synergism, use lentinan powder prevention sclerosis of blood vessels, reduce people's blood pressure; Use that the grifolan powder is anticancer, defying age, enhancing immunity; Use the Morchella esculenta (L.) Pers polysaccharide powder to improve human body comprehensive immunity, resist all kinds of fatigue syndrome; Use the lycium barbarum polysaccharide powder to regulate immunity, slow down aging; Add the oligomeric xylose toxin expelling, prevent constipation, increase body to the absorption of calcium, impel body to generate the multiple nutrients material; Overcome the effectiveness deficiency that present existing polysaccharide food exists, the defective of function singleness comprehensively improves the human body immunity of organisms.
Technical scheme of the present invention:
By weight:
Lentinan powder 15～30%
Grifolan powder 3～7%
Morchella esculenta (L.) Pers polysaccharide powder 3～7%
Lycium barbarum polysaccharide powder 10～20%
Compound vitamin B 0.1～0.8%
Oligomeric xylose 10～20%
Starch 58.6～14.3%
Magnesium stearate 0.3～0.9%
Production technology:
For guaranteeing product quality, all operations all should carry out in 100,000 grades GMP workshop.
Select lentinan powder, grifolan powder, Morchella esculenta (L.) Pers polysaccharide powder, lycium barbarum polysaccharide powder, compound vitamin for use, oligomeric xylose is a primary raw material, auxiliary with starch and magnesium stearate, add material, mixing, system granule, drying, granulate, tabletting, check, packing, finished product according to weight proportion, promptly have the auxiliary tablet product that improves body immunity.
Technological merit of the present invention:
It is primary raw material that the present invention adopts lentinan powder, grifolan powder, Morchella esculenta (L.) Pers polysaccharide powder, lycium barbarum polysaccharide powder, compound vitamin B and oligomeric xylose etc., through the science compatibility, give full play to its synergism, use lentinan powder prevention sclerosis of blood vessels, reduce people's blood pressure; Use that the grifolan powder is anticancer, defying age, enhancing immunity; Use the Morchella esculenta (L.) Pers polysaccharide powder to improve human body comprehensive immunity, resist all kinds of fatigue syndrome; Use the lycium barbarum polysaccharide powder to regulate immunity, slow down aging; Add the oligomeric xylose toxin expelling, prevent constipation, increase body to the absorption of calcium, impel body to generate the multiple nutrients material; Overcome the effectiveness deficiency that present existing polysaccharide food exists, the defective of function singleness comprehensively improves the human body immunity of organisms.
The specific embodiment:
Embodiment 1
The present invention has the auxiliary tablet product that improves body immunity, it is characterized in that it is the product made from the raw material of following weight ratio:
Prescription:
Lentinan powder 15
Grifolan powder 6%
Morchella esculenta (L.) Pers polysaccharide powder 6%
Lycium barbarum polysaccharide powder 20%
Compound vitamin B 0.2%
Oligomeric xylose 18%
Starch 34.4%
Magnesium stearate 0.4%
Add material, mixing, system granule, drying, granulate, tabletting, check, packing, finished product according to weight proportion, promptly make tablet product with auxiliary raising body immunity.
Embodiment 2
The present invention has the auxiliary tablet product that improves body immunity, it is characterized in that it is the product made from the raw material of following weight ratio:
Prescription:
Lentinan powder 22%
Grifolan powder 5%
Morchella esculenta (L.) Pers polysaccharide powder 5%
Lycium barbarum polysaccharide powder 15%
Compound vitamin B 0.5%
Oligomeric xylose 15%
Starch 36.9%
Magnesium stearate 0.6%
Technology according to embodiment 1 is made tablet.
Embodiment 3
The present invention has the auxiliary tablet product that improves body immunity, it is characterized in that it is the product made from the raw material of following weight ratio:
Prescription:
Lentinan powder 30%
Grifolan powder 4%
Morchella esculenta (L.) Pers polysaccharide powder 4%
Lycium barbarum polysaccharide powder 10%
Compound vitamin B 0.7%
Oligomeric xylose 12%
Starch 38.5%
Magnesium stearate 0.8%
Technology according to embodiment 1 is made tablet.
Claims (1)
1. assist the tablet product that improves body immunity for one kind, it is characterized in that: it is the product made from the raw material of following weight ratio,
Prescription:
By weight:
Lentinan powder 15～30%
Grifolan powder 3～7%
Morchella esculenta (L.) Pers polysaccharide powder 3～7%
Lycium barbarum polysaccharide powder 10～20%
Compound vitamin B 0.1～0.8%
Oligomeric xylose 10～20%
Starch 58.6～14.3%
Magnesium stearate 0.3～0.9%.
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| Application Number | Priority Date | Filing Date | Title |
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| CNB2005101259993A CN100379427C (en) | 2005-12-02 | 2005-12-02 | Tablet auxiliary product for increase of body immunological competence |
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| CNB2005101259993A CN100379427C (en) | 2005-12-02 | 2005-12-02 | Tablet auxiliary product for increase of body immunological competence |
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| CN100379427C true CN100379427C (en) | 2008-04-09 |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102552540B (en) * | 2012-01-10 | 2013-08-07 | 南京威泰珐玛兽药研究所有限公司 | Traditional Chinese medicine composition for enhancing immunity and preparation method thereof |
| CN104434849A (en) * | 2014-12-10 | 2015-03-25 | 浙江方格药业有限公司 | Grifola frondosa tablet and preparation method thereof |
| CN111011566A (en) * | 2019-11-07 | 2020-04-17 | 哈尔滨梵境园生物科技有限公司 | Orally disintegrating candy tablet with immunoregulation function |
| CN115088846A (en) * | 2022-05-31 | 2022-09-23 | 十堰市武当山旅游经济特区净界健康管理有限公司 | Composite millet bacteria polysaccharide oligomer powder for enhancing immune function and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1620920A (en) * | 2004-12-31 | 2005-06-01 | 北京东方兴企食品工业技术有限公司 | Composite fungi amylose nutrient |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1620920A (en) * | 2004-12-31 | 2005-06-01 | 北京东方兴企食品工业技术有限公司 | Composite fungi amylose nutrient |
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