CN100356902C - Toothpaste containing anion and cation surface activator and production thereof - Google Patents
Toothpaste containing anion and cation surface activator and production thereof Download PDFInfo
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- CN100356902C CN100356902C CNB2005100374015A CN200510037401A CN100356902C CN 100356902 C CN100356902 C CN 100356902C CN B2005100374015 A CNB2005100374015 A CN B2005100374015A CN 200510037401 A CN200510037401 A CN 200510037401A CN 100356902 C CN100356902 C CN 100356902C
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- toothpaste
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- anionic surfactant
- surfactant
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Abstract
The present invention discloses toothpaste which comprises anion and cation surface surfactants. The present invention contains thickening agents, abrasive agents, essences, sweeteners, preservatives, humectants, non-ionic surface surfactants, cationic surface surfactants and anionic surface surfactants. Non-ionic surface surfactants are added to the components of the toothpaste, and have the advantages of high surface activity, small surface tension of aqueous solution, large polymerization number of micelles, strong solubilization and good emulsifying ability. The aqueous solubility of cationic and anionic surface surfactants is greatly added, the mutual solution in water of anions and the cations is realized, and the antibacterial property and the emulsifiability of the toothpaste are enhanced.
Description
Technical field
The present invention relates to a kind of toothpaste and manufacture method thereof, refer in particular to a kind of toothpaste and manufacture method thereof that contains cationic and anionic surfactant.
Background technology
As everyone knows, the main effect of toothpaste is sterilization, in existing toothpaste preparation, often add some auxiliary agents such as cationic surfactant or anion surfactant, to promote the effect of toothpaste, wherein, cationic surfactant plays bactericidal action, and anion surfactant plays cleaning, bubbles, emulsification, but add in the toothpaste if both simply mix, then can react and produce precipitation, do not bring into play effect separately, bactericidal effect is not good, and foam volume is low.Because anion surfactant and cationic surfactant produce reaction in the toothpaste, cause both to lose efficacy.
In view of this, provide the toothpaste of a kind of anion and cationic surfactant coexistence and manufacture method thereof real for necessary.
Summary of the invention
Main purpose of the present invention is to provide the toothpaste and the manufacture method thereof of a kind of anion and cationic surfactant coexistence.
A kind of toothpaste that contains cationic and anionic surfactant contains thickening agent, abrasivus, essence, sweeting agent, antiseptic, wetting agent, non-ionic surface active agent, cationic surfactant and anion surfactant.
Wherein, non-ionic surface active agent can be in oxirane and the different propane block copolymer of epoxy (Poloxamer), polyoxyethylene sorbitol, propylene glycol condensates, polyoxyethylene addition castor oil hydrogenated or the sorbitol glucosides fatty acid ester choose any one kind of them or multiple.Thickening agent be in sodium carboxymethyl cellulose and hydroxyethyl-cellulose, HANSHENGJIAO, carrageenan, acrylate, the guar gum choose any one kind of them or multiple.Anion surfactant be in sodium lauryl sulphate, sodium N-lauroyl sarcosinate, the lauryl sodium glutamate choose any one kind of them or multiple.Described cationic surfactant is to choose any one kind of them in Ceepryn Cetylpyridinium Hexadecylpyridinium N-Hexadecylpyridinium or the domiphen bromide (DomiphenBromide).Abrasivus is a silicon dioxide; Sweeting agent is a saccharin sodium; Wetting agent is choosing any one kind of them or two kinds in glycerol or the sorbitol.
In the present invention, the described ratio range of toothpaste that this contains cationic and anionic surfactant is as described below:
Thickening agent 0.8-1.5% non-ionic surface active agent 0.5-1.5%
Cationic surfactant 0.5-1% anion surfactant 1.5-2.5%
Wetting agent 25-60% essence 0.8-1.5%
Sweeting agent 0.15-0.3% antiseptic 0.3-0.5%
Abrasivus 15-25% deionized water surplus.
The present invention also provides this to contain the manufacture method of the toothpaste of cationic and anionic surfactant, and it may further comprise the steps:
Step 1 at first, drops into non-ionic surface active agent in the water, is stirred to transparent clarification fast;
Step 2 then, adds sweeting agent and antiseptic in said mixture, pours the wetting agent mixing and stirring again into, obtains component A;
Step 3 then, is sneaked into cationic surfactant and thickening agent in water or the glycerol, and mixing and stirring promptly obtains B component;
Step 4, last, B component is added among the component A, to wherein adding after abrasive is stirred to evenly, add anion surfactant again, add essence, stir and outgas, can obtain finished product.
Compared with prior art, the present invention has added non-ionic surface active agent in toothpaste component, it has higher surface activity, the surface tension of aqueous solution is little, the micelle aggregate number is big, and solubilization is strong, has the good emulsifying ability, increased the dissolubility of cationic and anionic surfactant in water greatly, made that zwitterion can be molten altogether in water.Both improve the anti-microbial property of toothpaste, also improved its emulsifiability.
The specific embodiment
The invention provides a kind of toothpaste that contains cationic and anionic surfactant, it includes: thickening agent (binding agent), non-ionic surface active agent, cationic surfactant, anion surfactant, abrasivus, essence, sweeting agent and wetting agent.
Wherein, thickening agent be in sodium carboxymethyl cellulose and hydroxyethyl-cellulose, HANSHENGJIAO, carrageenan, acrylate, the guar gum choose any one kind of them or multiple.
Non-ionic surface active agent can be in oxirane and the different propane block copolymer of epoxy (Poloxamer), polyoxyethylene sorbitol, propylene glycol condensates, polyoxyethylene addition castor oil hydrogenated or the sorbitol glucosides fatty acid ester choose any one kind of them or multiple.Wherein, the different propane block copolymer of oxirane and epoxy can be oxirane and the different propane block copolymer 407 of epoxy.Polyoxyethylene sorbitol can be the polyoxyethylene sorbitol monoesters, as PEG (40) sorbitol glucosides, polysorbate (tween).
Anion surfactant be in sodium lauryl sulphate, sodium N-lauroyl sarcosinate, the lauryl sodium glutamate choose any one kind of them or multiple, it plays cleaning, emulsifying, blistered effect as emulsifying agent.
It is Powdered cationic surfactant, and as the antibacterial in the toothpaste, it can be pyridine compounds and their, as Ceepryn Cetylpyridinium Hexadecylpyridinium N-Hexadecylpyridinium; Domiphen bromide (Domiphen Bromide); Many biguanides are as two one or two guanidines; Quaternary ammonium salt compound is as the cetyl pyridinium hydrochlorate; Two pyridine ammonium analog derivatives are as octenyl pyridine ammonium; Pyrimidine derivatives is as pyrimidine; The salt that amidine analog derivative and above-mentioned each material and the acid of oral cavity acceptable form.Wherein, the preferred cationic surfactant is Ceepryn Cetylpyridinium Hexadecylpyridinium N-Hexadecylpyridinium and domiphen bromide.
Abrasivus is insoluble compound or slightly soluble compound, and insoluble compound can be silicon dioxide, zinc orthophosphate, plastic pellet, oxidation alum clay, hydrated alumina and calcium pyrophosphate or their mixture; Slightly soluble compound can be calcium carbonate, calcium phosphate, magnesium carbonate, insoluble Polymeric sodium metaphosphate., or their mixture.Preferred abrasive is a silicon dioxide, and suitable silicon dioxide comprises natural amorphous silica, as kieselguhr; Synthetic amorphous silica, as precipitated silica or silica gel, as silica xerogel, or their mixture.
Sweeting agent is a saccharin sodium.Wetting agent is choosing any one kind of them or two kinds in glycerol or the sorbitol.
In another embodiment of the present invention, the described toothpaste that contains cationic and anionic surfactant also further includes antiseptic.
Below further describe the formulation of toothpaste that this contains cationic and anionic surfactant by specific embodiment:
Thickening agent 0.8-1.5% non-ionic surface active agent 0.5-1.5%
Cationic surfactant 0.5-1% anion surfactant 1.5-2.5%
Wetting agent 25-60% essence 0.8-1.5%
Sweeting agent 0.15-0.3% antiseptic 0.3-0.5%
Abrasivus 15-25% deionized water surplus.
Embodiment one
In the present embodiment, this formulation of toothpaste that contains cationic and anionic surfactant is:
Sodium carboxymethyl cellulose 0.8% hydroxyethyl-cellulose 0.3%
Poloxamer407 1% Ceepryn Cetylpyridinium Hexadecylpyridinium N-Hexadecylpyridinium 1%
Sodium lauryl sulphate 2% essence 1.2%
Glycerol 10% sorbitol 30%
Silicon dioxide 20% saccharin sodium 0.3%
Sodium benzoate 0.5% deionized water surplus.
Embodiment two
In the present embodiment, this formulation of toothpaste that contains cationic and anionic surfactant is:
Sodium carboxymethyl cellulose 0.8% HANSHENGJIAO 0.3%
Poloxamer407 1% domiphen bromide 1%
Sodium lauryl sulphate 2% essence 1.2%
Glycerol 10% sorbitol 30%
Silicon dioxide 20% saccharin sodium 0.3%
Sodium benzoate 0.5% deionized water surplus.
Embodiment three
In the present embodiment, this formulation of toothpaste that contains cationic and anionic surfactant is:
Sodium carboxymethyl cellulose 0.5% hydroxyethyl-cellulose 0.3%
Poloxamer407 0.5% Ceepryn Cetylpyridinium Hexadecylpyridinium N-Hexadecylpyridinium 0.5%
Sodium lauryl sulphate 1.5% essence 0.8%
Glycerol 10% sorbitol 15%
Silicon dioxide 25% saccharin sodium 0.15%
Sodium benzoate 0.3% deionized water surplus.
Embodiment four
In the present embodiment, this formulation of toothpaste that contains cationic and anionic surfactant is:
Sodium carboxymethyl cellulose 1.0% HANSHENGJIAO 0.5%
Poloxamer407 1.5% domiphen bromide 1.0%
Sodium lauryl sulphate 2.5% essence 1.5%
Glycerol 20% sorbitol 4 0%
Silica 1 5% saccharin sodium 0.3%
Sodium benzoate 0.5% deionized water surplus.
The manufacture method that the present invention contains the toothpaste of cationic and anionic surfactant is below described:
Step 1 at first, drops into non-ionic surface active agent in the water, and stir about 10-15 minute fast, to transparent clarification;
Step 2 then, adds sweeting agent and antiseptic in said mixture, pours the wetting agent mixing and stirring again into, obtains component A;
Step 3 then, is sneaked into cationic surfactant and thickening agent in water or the glycerol, and mixing and stirring promptly obtains B component;
Step 4, at last, B component is added among the component A, stir about 20 minutes to wherein adding abrasive stir about 15 minutes after evenly, adds anion surfactant again, stirred 10 minutes, add essence, stir and outgas, can obtain the toothpaste that contains cationic and anionic surfactant of the present invention.
Above disclosedly only contain the toothpaste of cationic and anionic surfactant and the preferred embodiment of manufacture method thereof for the present invention is a kind of, certainly can not limit the present invention's interest field with this, therefore the equivalent variations of being done according to the present patent application claim still belongs to the scope that the present invention is contained.
Claims (10)
1. a toothpaste that contains cationic and anionic surfactant is characterized in that including non-ionic surface active agent, cationic surfactant and anion surfactant, and its ratio range is:
Thickening agent 0.8-1.5% non-ionic surface active agent 0.5-1.5%
Cationic surfactant 0.5-1% anion surfactant 1.5-2.5%
Wetting agent 25-60% essence 0.8-1.5%
Sweeting agent 0.15-0.3% antiseptic 0.3-0.5%
Abrasivus 15-25% deionized water surplus.
2. the toothpaste that contains cationic and anionic surfactant as claimed in claim 1 is characterized in that: described non-ionic surface active agent is choosing any one kind of them in the different propane block copolymer of oxirane and epoxy, polyoxyethylene sorbitol, propylene glycol condensates, polyoxyethylene addition castor oil hydrogenated or the sorbitol glucosides fatty acid ester.
3. the toothpaste that contains cationic and anionic surfactant as claimed in claim 2 is characterized in that: the different propane block copolymer of described oxirane and epoxy is the different propane block copolymer 407 of oxirane and epoxy.
4. the toothpaste that contains cationic and anionic surfactant as claimed in claim 1 is characterized in that: described cationic surfactant is to choose any one kind of them in Ceepryn Cetylpyridinium Hexadecylpyridinium N-Hexadecylpyridinium, domiphen bromide, two one or two guanidines, cetyl pyridinium hydrochlorate, octenyl pyridine ammonium, the pyrimidine and above-mentioned each material and the sour salt that forms of oral cavity acceptable; Anion surfactant be in sodium lauryl sulphate, sodium N-lauroyl sarcosinate, the lauryl sodium glutamate choose any one kind of them or multiple.
5. the toothpaste that contains cationic and anionic surfactant as claimed in claim 1 is characterized in that: described thickening agent be in sodium carboxymethyl cellulose, hydroxyethyl-cellulose, HANSHENGJIAO, carrageenan, acrylate, the guar gum choose any one kind of them or multiple.
6. the toothpaste that contains cationic and anionic surfactant as claimed in claim 1 is characterized in that: described this contains the component of the toothpaste of cationic and anionic surfactant:
Sodium carboxymethyl cellulose 0.8% hydroxyethyl-cellulose 0.3%
Different third Ceepryn Cetylpyridinium Hexadecylpyridinium N-Hexadecylpyridinium 1% of oxirane and epoxy
Alkane block copolymer 407 1% essence 1.2%
Sodium lauryl sulphate 2% sorbitol 30%
Glycerol 10% saccharin sodium 0.3%
Silicon dioxide 20% sodium benzoate 0.5%
The deionized water surplus.
7. the toothpaste that contains cationic and anionic surfactant as claimed in claim 1 is characterized in that: described this contains the component of the toothpaste of cationic and anionic surfactant:
Sodium carboxymethyl cellulose 0.8% HANSHENGJIAO 0.3%
Oxirane and expoxy propane domiphen bromide 1%
Block copolymer 407 1% essence 1.2%
Sodium lauryl sulphate 2% sorbitol 30%
Glycerol 10%
Silicon dioxide 20% saccharin sodium 0.3%
Sodium benzoate 0.5% deionized water surplus.
8. the toothpaste that contains cationic and anionic surfactant as claimed in claim 1 is characterized in that: described this contains the component of the toothpaste of cationic and anionic surfactant:
Sodium carboxymethyl cellulose 0.5% hydroxyethyl-cellulose 0.3%
Oxirane and epoxy the third 0.5% Ceepryn Cetylpyridinium Hexadecylpyridinium N-Hexadecylpyridiniums 0.5%
Alkane block copolymer 407 essence 0.8%
Sodium lauryl sulphate 1.5% sorbitol 15%
Glycerol 10% saccharin sodium 0.15%
Silicon dioxide 25% sodium benzoate 0.3%
The deionized water surplus.
9. the toothpaste that contains cationic and anionic surfactant as claimed in claim 1 is characterized in that: described this contains the component of the toothpaste of cationic and anionic surfactant:
Sodium carboxymethyl cellulose 1.0% HANSHENGJIAO 0.5%
Oxirane and epoxy third domiphen bromide 1.0%
Alkane block copolymer 407 1.5% essence 1.5%
Sodium lauryl sulphate 2.5% sorbitol 40%
Glycerol 20% saccharin sodium 0.3%
Silica 1 5% sodium benzoate 0.5%
The deionized water surplus.
10. manufacture method that contains the toothpaste of cationic and anionic surfactant is characterized in that may further comprise the steps:
At first, non-ionic surface active agent is dropped in the water, be stirred to transparent clarification fast;
Then, add sweeting agent and antiseptic in said mixture, pour the wetting agent mixing and stirring again into, obtain component A;
Then, cationic surfactant and thickening agent are sneaked in water or the glycerol, mixing and stirring promptly obtains B component;
At last, B component is added among the component A, to wherein adding after abrasive is stirred to evenly, add anion surfactant again, add essence, stir and outgas, can obtain finished product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100374015A CN100356902C (en) | 2005-09-21 | 2005-09-21 | Toothpaste containing anion and cation surface activator and production thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100374015A CN100356902C (en) | 2005-09-21 | 2005-09-21 | Toothpaste containing anion and cation surface activator and production thereof |
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| Publication Number | Publication Date |
|---|---|
| CN1745743A CN1745743A (en) | 2006-03-15 |
| CN100356902C true CN100356902C (en) | 2007-12-26 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNB2005100374015A Expired - Fee Related CN100356902C (en) | 2005-09-21 | 2005-09-21 | Toothpaste containing anion and cation surface activator and production thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI710378B (en) * | 2015-09-30 | 2020-11-21 | 南韓商愛茉莉太平洋股份有限公司 | Use of combination of cationic surfactant, anionic surfactant and viscosity increasing agnet for the preparation of shapable composition for hair care, and the product thereof |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107157785A (en) * | 2017-05-18 | 2017-09-15 | 中国人民解放军第四军医大学 | A kind of remineralization of teeth toothpaste and preparation method thereof |
| JP2020521792A (en) | 2017-05-31 | 2020-07-27 | エルジー ハウスホールド アンド ヘルスケア リミテッド | Pump type dentifrice composition |
| CN111135106A (en) * | 2020-02-12 | 2020-05-12 | 常德集智生物科技有限公司 | Green anti-inflammatory and bactericidal toothpaste |
| CN114948774B (en) * | 2022-07-29 | 2022-11-01 | 山东新华莎罗雅生物技术有限公司 | Disinfecting hand sanitizer with coexistence of anions and cations and preparation method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1092644A (en) * | 1993-12-11 | 1994-09-28 | 中国人民解放军第四军医大学口腔医学院 | Mouth sweetening agent |
| CN1115636A (en) * | 1994-07-26 | 1996-01-31 | 许绍聪 | Prepn of multiple-effect oral cavity health care liquid |
| CN1221333A (en) * | 1996-06-07 | 1999-06-30 | 科尔加特·帕尔莫利弗公司 | Surfactant system for remoting antibacterial uptake on dental tissue |
| JP2001131580A (en) * | 1999-11-04 | 2001-05-15 | Kao Corp | Detergent composition |
| CN1522149A (en) * | 2000-06-30 | 2004-08-18 | Promoting whole body health |
-
2005
- 2005-09-21 CN CNB2005100374015A patent/CN100356902C/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1092644A (en) * | 1993-12-11 | 1994-09-28 | 中国人民解放军第四军医大学口腔医学院 | Mouth sweetening agent |
| CN1115636A (en) * | 1994-07-26 | 1996-01-31 | 许绍聪 | Prepn of multiple-effect oral cavity health care liquid |
| CN1221333A (en) * | 1996-06-07 | 1999-06-30 | 科尔加特·帕尔莫利弗公司 | Surfactant system for remoting antibacterial uptake on dental tissue |
| JP2001131580A (en) * | 1999-11-04 | 2001-05-15 | Kao Corp | Detergent composition |
| CN1522149A (en) * | 2000-06-30 | 2004-08-18 | Promoting whole body health |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI710378B (en) * | 2015-09-30 | 2020-11-21 | 南韓商愛茉莉太平洋股份有限公司 | Use of combination of cationic surfactant, anionic surfactant and viscosity increasing agnet for the preparation of shapable composition for hair care, and the product thereof |
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| Publication number | Publication date |
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| CN1745743A (en) | 2006-03-15 |
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