CN100350936C

CN100350936C - Chinese medicine external-use powder for treating ulcerative stomatitis

Info

Publication number: CN100350936C
Application number: CNB2005100964169A
Authority: CN
Inventors: 韩小锋
Original assignee: Individual
Current assignee: Individual
Priority date: 2005-11-24
Filing date: 2005-11-24
Publication date: 2007-11-28
Anticipated expiration: 2025-11-24
Also published as: CN1814098A

Abstract

The present invention relates to external-use Chinese medicinal powder for treating dental ulcer. The Chinese external-use medicinal powder has raw materials with the following medicinal material composition and the proportion by weight: 65% to 85% of Chinese gall, 8% to 18% of red lead, 2% to 11% of snake slough and 1% to 6% of dragon blood. The present invention has the functions of dispersing swelling, relieving pain and promoting ulcer healing, is capable of being directly used for ulcer surfaces, shortens the treatment course and has quick effects. The present invention belongs to a pure Chinese medicinal preparation and has the advantages of no toxic or side effect, wide range and easy acquisition of medicine sources, convenient application, external coating application at affected parts, low dosage, low cost and no pain hydrostomia caused by the medicine; the present invention has conspicuous curative effects on light dental ulcer and also has effects on fungous oral infection caused by chemotherapy broad spectrum antibiotics.

Description

A kind of Chinese medicine external pulvis for the treatment of oral ulcer

Technical field

The present invention relates to a kind of Chinese patent medicine for the treatment of oral ulcer, particularly relate to a kind of Chinese medicine external pulvis for the treatment of oral ulcer.

Background technology

Recurrent aphtha (RAU), alias: recurrent oral ulceration (ROU), recurrent aphtha etc. are modal diseases in the diseases of oral mucosa, prevalence occupies the first place of diseases of oral mucosa up to 20%.Because of having tangible causalgia, thus the bandit with Greek " aphtha "-causalgia.In this ratio, in state-owned 2.6 hundred million, the whole world has 1,000,000,000 populations to suffer from oral ulcer, and outbreak repeatedly, the Focus host of the Chinese Central Television (CCTV) respects a pellet, steps on literary composition on the health newspaper, to the medicine of whole nation collection treatment oral ulcer.

Existing therapeutic profile: because of definite etiology unknown, though thereby Therapeutic Method many, curative effect is all undesirable.Topical therapeutic antibiotic medicine, analgesic, corrosive medicine are main, and whole body therapeutic is based on hormone and other immune formulation, expense height and weak curative effect.Have in the market: 1, the double-deck sticking tablet of the hormone medicine dexamethasone acetate of Shenzhen Mrs pharmacy group production---easily can post certain curative effect, a lot of contraindications are arranged, certain limitation is arranged; 2, too oral ulcer spirit of Wu: vitamin medicaments, uncertain therapeutic efficacy is cut; 3, BINGPENG SAN: with the back sharp ache; 4, active silver ion collutory: the heavy metal class, country prohibites; 5, hibitane KOUQIANG KUIYANG MO: based on sterilization; 6, because of not being the disease that bacterial infection causes certainly, so be blindly to cure the disease, there are the defective of hormone in antibiotic and hormone mix preparation equally; Immunostimulants such as 7, transfer factor, left-handed rice azoles, based on the treatment general disease, no specific aim, expense height.

Summary of the invention

The objective of the invention is for overcoming disadvantages of background technology, and a kind of short treating period, instant effect are provided, expense is low and the Chinese medicine external pulvis of the treatment oral ulcer that has no side effect.

The present invention realizes by the following technical solutions: make that medical material in the raw material of this medicine is formed and percentage by weight is:

Galla Chinensis 65%～85% Plumbum preparatium 8%～18% Periostracum Serpentis, 2%～11% Sanguis Draxonis 1%～6%.

Be monarch drug with the Galla Chinensis among the side of the present invention, Periostracum Serpentis is a ministerial drug.The Galla Chinensis nature and flavor: acid is flat, Gui Jing: lung stomach large intestine, function: hemostasis detoxifcation, treatment: traumatic hemorrhage, toxic swelling furuncle, hold back ulcer, incised wound, its pharmacology is: 1, astriction: because its contained tannic acid has precipitation to protein, behind skin, mucosa, the ulcer contact tannic acid, its tissue protein promptly is solidified, cause one deck tunicle and be astriction, the also oppressed contraction of little blood vessel simultaneously, blood clotting and play hemostasia effect, teleneuron protein is solidified, and can be faint local anesthesia phenomenon; 2, antibacterial action: in vitro tests all has significantly antibacterial or bactericidal action to staphylococcus aureus, streptococcus, streptococcus pneumoniae and typhoid fever, paratyphoid fever, dysentery, anthrax, diphtheria, bacillus pyocyaneus etc., mainly be distributed in skin zone, the Galla Chinensis decoct has inhibitory action to the influenza PR8 strain of influenza virus type A virus that is inoculated in Embryo Gallus domesticus.Periostracum Serpentis nature and flavor: Gan Xianping returns through liver, function: detumescence, parasite killing, treatment: acute throat trouble aphtha, swollen and rigid tongue congenital deformity of the tongue, furuncle carbuncle, parotitis.Plumbum preparatium, Sanguis Draxonis are adjuvant drug altogether, the Plumbum preparatium nature and flavor: hot salty-cold return through: heart spleen liver function is used: removing toxic substances and promoting granulation cures mainly: ulcer carbuncle, aphtha, incised wound are hemorrhage; Sanguis Draxonis nature and flavor: Gan Xianping, return through: the heart, liver, function: the dissipating blood stasis analgesic therapy, hemostasia and promoting granulation cures mainly: continuous bleeding due to traumatic injury, ecthyma unhealed for long time has antifungic action.Full side has reducing swelling and alleviating pain, promotes the effect of ulcer healing, from above-mentioned argumentation as can be known, no matter the present invention cures mainly from function, still all different in the side's of condemning medication with former Chinese patent medicine, not only pointed, and be directly used in ulcer surface, have reducing swelling and alleviating pain and promote ulcer healing, the characteristics that shorten the course of treatment.

The present invention compared with prior art has the following advantages: the present invention has reducing swelling and alleviating pain, promotes the effect of ulcer healing, is directly used in ulcer surface, shortens the course of treatment, instant effect the invention belongs to pure Chinese medicinal preparation, has no side effect, the medicine source extensively is easy to get, it is convenient to use, affected part of exterior coating, and consumption is few, expense is low, there is not drug-induced pain sialorrhea, especially evident in efficacy to light-duty oral ulcer, effective equally to the mycotic oral cavity infection that the chemotherapy broad ectrum antibiotic causes.

The specific embodiment

Embodiment 1

Make that medical material in the raw material of this embodiment is formed and percentage by weight is:

Galla Chinensis 65% Plumbum preparatium 18% Periostracum Serpentis, 11% Sanguis Draxonis 6%.

The preparation technology of present embodiment is: prepare medicine according to the national drug sanitary standard, above-mentioned four Chinese medicine is ground into powder with mortar respectively, cross the 80-100 mesh sieve, grind well bottling, every bottled 1g once more with mortar after will being ground into the four Chinese medicine mixing of powder then.

Embodiment 2

Galla Chinensis 85% Plumbum preparatium 8% Periostracum Serpentis, 2% Sanguis Draxonis 5%.

The preparation technology of present embodiment is with embodiment 1.

Embodiment 3

Galla Chinensis 85% Plumbum preparatium 10% Periostracum Serpentis, 4% Sanguis Draxonis 1%.

The preparation technology of present embodiment is with embodiment 1.

Embodiment 4

Galla Chinensis 77% Plumbum preparatium 13% Periostracum Serpentis, 6.5% Sanguis Draxonis 3.5%.

The preparation technology of present embodiment is with embodiment 1.

Embodiment 5

Galla Chinensis 75% Plumbum preparatium 15% Periostracum Serpentis, 8% Sanguis Draxonis 2%.

The preparation technology of present embodiment is with embodiment 1.

Embodiment 6

Galla Chinensis 80% Plumbum preparatium 9% Periostracum Serpentis, 7% Sanguis Draxonis 4%.

The preparation technology of present embodiment is with embodiment 1.

Usage and dosage of the present invention: be stained with 30-40mg medicated powder with cotton swab at every turn and be coated with the affected part, every day 3-4 time.

Diagnostic criteria: 1, light-duty oral ulcer: the most common, account for 80% of RAU, general diameter 2-4mm, round or oval, clear on every side, isolated being dispersed in, number is few, and each 1-5 is not waited, good sending out in the relatively poor zone of keratinization degree, as lip cheek mucosa, the gum palatine that the keratinization degree is high is less, during outbreak ulcer have " recessed; red; Huang; feature bitterly ", i.e. ulcer concavity, substrate is not hard, periphery is with the congested blush band of about 1mm, and the surface is covered with light yellow pseudomembrane, and the causalgia sense is obvious, infecting serious time companion's submandibular lymph nodes swells and ache, heating generally continues 1-2 week, and the intermission is different in size, because of the thorn Severe Pain influences language, feed, mood, thus quality of life is had a negative impact; 2, heavy oral ulcer: ulcer is big and dark during outbreak, " like the crater " diameter 10-30mm, the dark tela submucosa that reaches is until the flesh layer, and periphery is red and swollen to swell, and the substrate of laying one's hand on is harder, but neat in edge is clear, normal single generation, stage of attack, can reach a month surplus even several months, and pain is heavier, more can stay cicatrix after, rare; 3, herpes sample oral ulcer: ulcer is little, and diameter 2mm can reach more than the dozens of and many, but symptoms such as companioned with headache, low grade fever, general malaise, regional nodes's enlargement are rare.

Criterion of therapeutical effect: pain disappears, the oral ulcer surface healing.

Therapeutic Method: be stained with 30-40mg medicated powder with cotton swab at every turn and be coated with the affected part, every day 3-4 time, general 2-4 days is a course of treatment, just can cure a general course of treatment light-duty oral ulcer.

Function: detumescence, pain relieving, granulation promoting, hold back skin ulcer.

The present invention shows that through acute toxicity test the present invention is nontoxic.

The present invention is through clinical observation case 102 examples, 102 routine oral ulcer patients are adopted the outer oral cavity ulcer powder of the present invention that is coated with, be stained with 30-40mg medicated powder with cotton swab at every turn and be coated with the affected part, every day 3-4 time, the result shows: wherein 8 patients cured in one day, and 32 patients cured in two days, 37 patients cured in three days, 16 patients cured in four days, and 7 patients cured total effective rate 100% in five days.

Claims

1, a kind of Chinese medicine external pulvis for the treatment of oral ulcer is characterized in that being made by following raw material medicines in percentage by weight:

2, a kind of Chinese medicine external pulvis for the treatment of oral ulcer according to claim 1 is characterized in that being made by following raw material medicines in percentage by weight: