CN100349870C - 由仲氨基氧化物合成胺醚的方法及其应用 - Google Patents

由仲氨基氧化物合成胺醚的方法及其应用 Download PDF

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Publication number
CN100349870C
CN100349870C CNB028234219A CN02823421A CN100349870C CN 100349870 C CN100349870 C CN 100349870C CN B028234219 A CNB028234219 A CN B028234219A CN 02823421 A CN02823421 A CN 02823421A CN 100349870 C CN100349870 C CN 100349870C
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CN
China
Prior art keywords
alkyl
group
carbon atoms
iodide
phenyl
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Expired - Fee Related
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CNB028234219A
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English (en)
Chinese (zh)
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CN1592740A (zh
Inventor
M·弗雷
V·拉斯特
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BASF Schweiz AG
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Ciba Spezialitaetenchemie Holding AG
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/94—Oxygen atom, e.g. piperidine N-oxide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F4/00—Polymerisation catalysts
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/16—Nitrogen-containing compounds
    • C08K5/34—Heterocyclic compounds having nitrogen in the ring
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K15/00—Anti-oxidant compositions; Compositions inhibiting chemical change
    • C09K15/04—Anti-oxidant compositions; Compositions inhibiting chemical change containing organic compounds
    • C09K15/20—Anti-oxidant compositions; Compositions inhibiting chemical change containing organic compounds containing nitrogen and oxygen
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K15/00—Anti-oxidant compositions; Compositions inhibiting chemical change
    • C09K15/04—Anti-oxidant compositions; Compositions inhibiting chemical change containing organic compounds
    • C09K15/30—Anti-oxidant compositions; Compositions inhibiting chemical change containing organic compounds containing heterocyclic ring with at least one nitrogen atom as ring member

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CNB028234219A 2001-11-26 2002-11-19 由仲氨基氧化物合成胺醚的方法及其应用 Expired - Fee Related CN100349870C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01811143 2001-11-26
EP01811143.5 2001-11-26

Publications (2)

Publication Number Publication Date
CN1592740A CN1592740A (zh) 2005-03-09
CN100349870C true CN100349870C (zh) 2007-11-21

Family

ID=8184270

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB028234219A Expired - Fee Related CN100349870C (zh) 2001-11-26 2002-11-19 由仲氨基氧化物合成胺醚的方法及其应用

Country Status (11)

Country Link
US (1) US20050104042A1 (https=)
EP (1) EP1463717A2 (https=)
JP (1) JP2005516905A (https=)
KR (1) KR20040058329A (https=)
CN (1) CN100349870C (https=)
AU (1) AU2002352057A1 (https=)
BR (1) BR0214429A (https=)
CA (1) CA2464107A1 (https=)
MX (1) MXPA04004694A (https=)
TW (1) TW200407307A (https=)
WO (1) WO2003045919A2 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070191516A1 (en) * 2004-03-15 2007-08-16 Markus Frey Process for the synthesis of amine ethers
ES2562403T3 (es) * 2004-11-02 2016-03-04 Basf Se Proceso para la síntesis de N-alcoxiaminas
JP4873612B2 (ja) * 2005-12-20 2012-02-08 株式会社Ａｄｅｋａ ヒンダードアミン化合物の製造方法
JP2009541429A (ja) * 2006-07-05 2009-11-26 チバ ホールディング インコーポレーテッド 立体障害性ニトロキシルエーテルの製造方法
CN101484422B (zh) * 2006-07-05 2012-07-11 西巴控股有限公司 制备位阻硝酰基醚的方法
ATE493387T1 (de) * 2006-07-05 2011-01-15 Basf Se Verfahren zur herstellung sterisch gehinderter nitroxylether
CA2707158A1 (en) * 2007-11-28 2009-06-04 Revision Therapeutics, Inc. Modulators of ocular oxidative stress
CA2707047C (en) * 2007-12-12 2017-11-28 Rigel Pharmaceuticals, Inc. Carboxamide, sulfonamide and amine compounds for metabolic disorders

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1228424A (zh) * 1998-03-09 1999-09-15 西巴特殊化学品控股有限公司 1－烷氧基－多烷基－哌啶衍生物及其作为聚合调节剂的用途
CN1235159A (zh) * 1998-02-25 1999-11-17 西巴特殊化学品控股有限公司 空间位阻的胺醚的制备

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4921962A (en) * 1988-10-19 1990-05-01 Ciba-Geigy Corporation Process for preparing N-hydrocarbyloxy derivatives of sterically hindered amines
US5374729A (en) * 1992-05-07 1994-12-20 Ciba-Geigy Corporation Process for preparing N-methoxy derivatives of 4-hydroxy-2,2,6,6-tetramethylpiperidine and 2,2,6,6-tetramethyl-4-piperidone
ITMI980366A1 (it) * 1998-02-25 1999-08-25 Ciba Spec Chem Spa Preparazione di eteri amminici stericamente impediti
US6211378B1 (en) * 1998-10-13 2001-04-03 Ciba Specialty Chemicals Corporation Process for the synthesis of 4-substituted N-[(alk-2-en-1-yl)oxy]-and N-aralkyloxy-2,2,6,6-tetraalkylpiperidines
US6271377B1 (en) * 1999-02-25 2001-08-07 Ciba Specialty Chemicals Corporation Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith
US6166212A (en) * 1999-05-20 2000-12-26 Ciba Specialty Chemicals Corporation Process for the synthesis of N-(hydroxyalkoxy) substituted hindered amine stabilizers
TW572896B (en) * 2000-05-26 2004-01-21 Ciba Sc Holding Ag Process for the synthesis of amine ethers from secondary amino oxides
US6841668B2 (en) * 2002-04-11 2005-01-11 Ciba Specialty Chemicals Corporation Polyoxometalate catalysts for the preparation of sterically hindered N-substituted aryloxyamines

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1235159A (zh) * 1998-02-25 1999-11-17 西巴特殊化学品控股有限公司 空间位阻的胺醚的制备
CN1228424A (zh) * 1998-03-09 1999-09-15 西巴特殊化学品控股有限公司 1－烷氧基－多烷基－哌啶衍生物及其作为聚合调节剂的用途

Also Published As

Publication number Publication date
US20050104042A1 (en) 2005-05-19
WO2003045919A3 (en) 2004-04-29
CN1592740A (zh) 2005-03-09
EP1463717A2 (en) 2004-10-06
AU2002352057A8 (en) 2003-06-10
CA2464107A1 (en) 2003-06-05
MXPA04004694A (es) 2004-08-19
TW200407307A (en) 2004-05-16
JP2005516905A (ja) 2005-06-09
BR0214429A (pt) 2004-11-03
AU2002352057A1 (en) 2003-06-10
KR20040058329A (ko) 2004-07-03
WO2003045919A2 (en) 2003-06-05

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