CN100341484C - 部分可生物降解的温度和pH敏感的水凝胶 - Google Patents

部分可生物降解的温度和pH敏感的水凝胶 Download PDF

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Publication number
CN100341484C
CN100341484C CNB2003801084269A CN200380108426A CN100341484C CN 100341484 C CN100341484 C CN 100341484C CN B2003801084269 A CNB2003801084269 A CN B2003801084269A CN 200380108426 A CN200380108426 A CN 200380108426A CN 100341484 C CN100341484 C CN 100341484C
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China
Prior art keywords
dextran
hydrogel
weight
maleic acid
isopropylacrylamide
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Expired - Fee Related
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CNB2003801084269A
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English (en)
Chinese (zh)
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CN1735406A (zh
Inventor
C·－C·楚
X·－Z·张
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Cornell Research Foundation Inc
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Cornell Research Foundation Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52—Amides or imides
    • C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F220/56—Acrylamide; Methacrylamide
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/10—Esters
    • C08F222/12—Esters of phenols or saturated alcohols
    • C08F222/16—Esters having free carboxylic acid groups, e.g. monoalkyl maleates or fumarates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F251/00—Macromolecular compounds obtained by polymerising monomers on to polysaccharides or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L51/00—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • C08L51/02—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers grafted on to polysaccharides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
CNB2003801084269A 2003-01-16 2003-12-03 部分可生物降解的温度和pH敏感的水凝胶 Expired - Fee Related CN100341484C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44035503P 2003-01-16 2003-01-16
US60/440,355 2003-01-16

Publications (2)

Publication Number Publication Date
CN1735406A CN1735406A (zh) 2006-02-15
CN100341484C true CN100341484C (zh) 2007-10-10

Family

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Family Applications (1)

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CNB2003801084269A Expired - Fee Related CN100341484C (zh) 2003-01-16 2003-12-03 部分可生物降解的温度和pH敏感的水凝胶

Country Status (7)

Country Link
US (1) US7420024B2 (enExample)
EP (1) EP1583520A4 (enExample)
JP (1) JP2006515640A (enExample)
CN (1) CN100341484C (enExample)
AU (1) AU2003294258B2 (enExample)
CA (1) CA2513502C (enExample)
WO (1) WO2004064816A1 (enExample)

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JP4500263B2 (ja) * 2003-07-28 2010-07-14 帝人株式会社 温度応答性ハイドロゲル
KR100665672B1 (ko) 2005-04-13 2007-01-09 성균관대학교산학협력단 새로운 온도 및 ｐＨ 민감성 블록 공중합체 및 이를 이용한고분자 하이드로겔
ATE533791T1 (de) * 2005-09-27 2011-12-15 Univ Grenoble 1 Mit einer polymerisierbaren gruppierung funktionalisiertes hydrogel und anwendungen davon als biosensoren oder bioreaktoren
US9987221B2 (en) * 2007-08-23 2018-06-05 Boston Scientific Scimed, Inc. Injectable hydrogel compositions
US9150788B2 (en) * 2007-09-18 2015-10-06 Syracuse University Non-amphiphile-based water-in-water emulsion and uses thereof
US20090183503A1 (en) * 2008-01-18 2009-07-23 Alberto Verdesi Exhaust apparatus
CN102325814B (zh) * 2009-01-14 2014-03-12 康奈尔大学 用于生物医学用途的生物可降解型水凝胶的制备
US10669174B2 (en) 2011-10-26 2020-06-02 The University Of Kentucky Research Foundation Water purification device and a method of decontaminating a water supply
US9615573B1 (en) 2014-09-04 2017-04-11 Rose M. Moore Product and method for providing anti-microbial delivery
CN108017750A (zh) * 2017-06-28 2018-05-11 南华大学 一种温敏水凝胶保水剂及其制备方法和应用
CN107759725B (zh) 2017-11-10 2020-02-18 中国石油大学(华东) 一种适用于油井水泥浆的pH敏感性吸水树脂及其应用
CN109620689B (zh) * 2019-01-10 2020-06-05 浙江大学 一种基于软体复合膜的柔性器及人体表面持续按摩方法

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US6388047B1 (en) * 1999-04-12 2002-05-14 Cornell Research Foundation, Inc. Hydrogel-forming system with hydrophobic and hydrophilic components
US6476204B1 (en) * 1998-08-31 2002-11-05 Cornell Research Foundation, Inc. Dextran-maleic acid monoesters and hydrogels based thereon

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SE417431B (sv) * 1975-12-12 1981-03-16 Pharmacia Fine Chemicals Ab Dextranderivatgel for elektroforetisk separation
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JPS63118308A (ja) * 1986-11-06 1988-05-23 Nippon Synthetic Chem Ind Co Ltd:The 高吸水性樹脂の製造法
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US6476204B1 (en) * 1998-08-31 2002-11-05 Cornell Research Foundation, Inc. Dextran-maleic acid monoesters and hydrogels based thereon
US6388047B1 (en) * 1999-04-12 2002-05-14 Cornell Research Foundation, Inc. Hydrogel-forming system with hydrophobic and hydrophilic components

Also Published As

Publication number Publication date
CA2513502A1 (en) 2004-08-05
JP2006515640A (ja) 2006-06-01
CN1735406A (zh) 2006-02-15
AU2003294258B2 (en) 2009-05-28
EP1583520A1 (en) 2005-10-12
US7420024B2 (en) 2008-09-02
EP1583520A4 (en) 2007-05-23
WO2004064816A1 (en) 2004-08-05
AU2003294258A1 (en) 2004-08-13
US20060128918A1 (en) 2006-06-15
CA2513502C (en) 2012-02-07

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