CN100339125C - Chinese medicine composition for treating digestive system ulcer - Google Patents

Chinese medicine composition for treating digestive system ulcer Download PDF

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Publication number
CN100339125C
CN100339125C CNB2005100431639A CN200510043163A CN100339125C CN 100339125 C CN100339125 C CN 100339125C CN B2005100431639 A CNB2005100431639 A CN B2005100431639A CN 200510043163 A CN200510043163 A CN 200510043163A CN 100339125 C CN100339125 C CN 100339125C
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ulcer
chinese medicine
digestive system
radix
medicine composition
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CN1739758A (en
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贺拴友
范亚男
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Abstract

The present invention aims to provide a traditional Chinese medicine compound for effectively treating digestive system ulcer, which is prepared from amomun fruit, clove, cuttlebone, long pepper, concha arcae, dandelion, evodia, notoginseng, officinal magnolia bark, costus roots, liquorice and corresponding auxiliary material in any type on pharmacy after the general traditional Chinese medicines are decocted with water and extracted. The clinical experiment proves that the medicine of the present invention has the action of relieving sourness and pain, promoting qi circulation, dissipating cold and promoting ulcer healing and obvious treatment effect on treating stomach ulcer and duodenum ulcer, and the total effective rate is 98%.

Description

A kind of Chinese medicine composition for the treatment of digestive system and ulcer
Technical field
The invention belongs to the field of Chinese medicines, relate to a kind of pharmaceutical composition for the treatment of ulcer, relate in particular to a kind of Chinese medicine composition for the treatment of digestive system and ulcer.
Background technology
Ulcer is the common disease of digestive system, divides two kinds of gastric ulcer and duodenal ulcers.The ratio of the two is 1: 3, and men and women's ratio is 3-4: 1, and more the age sees, accounts for 70% with 20-50 year.Along with the growth of population mean age, gerontal patient's ratio increase to some extent.Because western medicine instant effect, treatment cycle are short, the general Western medicine that adopts when treatment gastric ulcer and duodenal ulcer at present, for example bisfentidine, proton pump inhibitor, motivator medicine etc., but since Western medicine strong according to patience, side effect is big, can not take for a long time, and easily recur etc.The traditional Chinese medical science is to the treatment of minute gastric ulcer and duodenal ulcer, adopts relieving gastric hyperacidity to alleviate stomachache, circulation of qi promoting cold expelling according to pathogenic factor, to promote the healing of ulcer surface, fundamentally treats ulcer, reaches the purpose for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition that can effectively treat digestive system and ulcer.
Theory of Chinese medical science is thought: ulcer is how unsuccessful because of feelings will, and it is sad angry to be worried, and daily life is careless, and eating and drinking without temperance and causing then causes ulcer, and treatment should be with relieving gastric hyperacidity to alleviate stomachache, and circulation of qi promoting cold expelling, promotion ulcer healing are order.Medicament selection Fructus Amomi of the present invention, Flos Caryophylli, Os Sepiae, Fructus Piperis Longi, Concha Arcae, Herba Taraxaci (former Chinese medicine name Herba Taraxaci, down together), Fructus Evodiae (former Chinese medicine name Fructus Evodiae, down together), Radix Notoginseng, Cortex Magnoliae Officinalis, Radix Aucklandiae (Radix Vladimiriae), several flavors of Radix Glycyrrhizae make up.This is according to theory of Chinese medical science, Fructus Amomi: acrid in the mouth, warm in nature, can removing dampness be amusing, the effect of relieving QI stagnancy in the stomach; Flos Caryophylli: acrid in the mouth, warm in nature, can stomach warming sending down the abnormal ascending QI, dispersing cold for relieving pain, kind cold syndrome of the stomach vomit leaf, singultus and the trusted subordinate's pain controlled; Os Sepiae: salty in the mouth, warm in nature, can astringing to arrest bleeding, relieving leukorrhea by astringents, be used for disease such as gastric and duodenal ulcers; Fructus Piperis Longi: acrid in the mouth, hot in nature, can warming the middle warmer and descending qi, dispersing cold for relieving pain; Concha Arcae: salty in the mouth, property are put down, and return liver taste warp, energy resolving phlegm and dissipating blood stasis, hard masses softening and resolving, relieving gastric hyperacidity to alleviate stomachache; Herba Taraxaci: bitter in the mouth, cold in nature, the effect of energy clearing heat, releasing toxin, removing swelling and dissipating stagnation; Fructus Evodiae: acrid in the mouth, hardship, hot in nature, energy dispersing cold for relieving pain, the soothing the liver therapeutic method to keep the adverse QI flowing downwards, dampness removing and diarrhea-relieving; Radix Notoginseng: sweet in the mouth, little hardship, warm in nature, the effect of dissipating blood stasis for subsidence of swelling, analgesic hemostatic is arranged; Cortex Magnoliae Officinalis: bitter in the mouth, property wet, the effect of the circulation of qi promoting of energy dampness, consumer product dredge stasis; Radix Aucklandiae (Radix Vladimiriae): acrid in the mouth, slightly warm in nature, energy promoting the circulation of QI to relieve pain, invigorating the spleen and regulating the stomach etc.; Radix Glycyrrhizae: distinguish the flavor of sweet, warm in nature, can QI invigorating invigorating middle warmer, relieving spasm to stop pain, nourishing the lung to arrest cough, eliminating fire and detoxication, coordinating the actions of various ingredients in a prescription.The present invention makes up above-mentioned each herbal medicine, make the effect of each medicine produce synergism, play relieving gastric hyperacidity to alleviate stomachache, the effect of circulation of qi promoting cold expelling, promotion ulcer healing, thereby can treat gastric ulcer and duodenal ulcer effectively, reach the purpose that does not recur, reaches thorough radical cure.
The consumption of drug component of the present invention is that the consumption of each component is advisable with following weight ratio part through a large amount of groping, sum up and get:
Fructus Amomi 40-80 part, Flos Caryophylli 10-40 part, Os Sepiae 50-90 part, Fructus Piperis Longi 20-60 part, Concha Arcae 30-70 part, Herba Taraxaci 10-40 part, Fructus Evodiae 0.5-2.0 part, Radix Notoginseng 0.3-0.9 part, Cortex Magnoliae Officinalis 10-40 part, Radix Aucklandiae (Radix Vladimiriae) 0.3-0.9 part, Radix Glycyrrhizae 0.3-0.9 part.
Pharmaceutical composition of the present invention, can adopt conventional Chinese medicine decocting to extract after, be equipped with adjuvant commonly used on the pharmaceutics, be prepared into any dosage form on the pharmaceutics.
The present invention is prepared into powder with described each ratio component by the conventional process for preparing powder.
The quality standard of medicinal composition powders of the present invention
[prescription] Fructus Amomi, Flos Caryophylli, Os Sepiae, Fructus Piperis Longi, Concha Arcae, Herba Taraxaci, Fructus Evodiae, Radix Notoginseng, Cortex Magnoliae Officinalis, Radix Aucklandiae (Radix Vladimiriae), Radix Glycyrrhizae etc.
Flavour of a drug during [method for making] will write out a prescription are chosen only, dry, pulverize, and mixing after the difference weighing, the packing pouch forms.
[character] chocolate brown powder, gas perfume (or spice), it is little sweet to distinguish the flavor of.
[inspection] should meet " the pertinent regulations under an appendix powder of Chinese pharmacopoeia version in 2000 item.
[function with cure mainly] relieving gastric hyperacidity to alleviate stomachache, the circulation of qi promoting cold expelling is used for gastric and duodenal ulcers.
[usage and consumption] is oral, each 5g, every day three times.
Clinical efficacy of the present invention is summed up:
Ulcer is the common disease of digestive system, divides two kinds of gastric ulcer and duodenal ulcers, and since 1999 to 2005, we observe 283 routine stomaches, duodenal ulcer patients, and existing 151 examples with complete data are summarized as follows:
Clinical data: 151 example ages are all between 20-67 year, married 109 examples, unmarried 42 examples, the course of disease 2 years to 21 years, 20-30 year 37 examples, 31-40 year 65 examples, 41-50 year 31 examples.18 examples in 51-67 year.Wherein, gastric ulcer 61 examples, duodenal ulcer 32 examples, gastroduodenal ulcer 58 examples.
Diagnostic criteria: all case all is diagnosed as the ulcer patient through barium meal, gastroscope.
Therapeutic Method: KUIYANG SAN, each 5g, gastric ulcer every day 3 times, duodenal ulcer is oral at whenever 30 minutes before the meal every day 4 times.If any other special circumstances, give anti symptom treatment.
Criterion of therapeutical effect: respectively make barium meal or gastroscope before treatment and after the treatment in advance with contrast.Healing, symptom and sign disappear, niche disappears.The also last complete obiteration of produce effects, clinical symptom disappearance, niche, or niche disappears but the also last complete obiteration person of clinical symptoms.Improvement, symptom and sign alleviate.The also last complete obiteration of niche.Clinical symptoms and niche and the preceding no significant difference of treatment before and after invalid, the treatment.
Therapeutic outcome: cure 129 examples (85.4%), produce effects 19 examples (12.6%), 2 examples that take a turn for the better (0.013%), invalid 1 example (0.007%), total effective rate is 98%.
The specific embodiment
Embodiment 1
Prescription:
40 parts of Fructus Amomis, 10 parts of Flos Caryophyllis, 50 parts of Os Sepiae, 20 parts of Fructus Piperis Longi, 30 parts of Concha Arcaes, 10 parts of Herba Taraxaci, 0.5 part of Fructus Evodiae, 0.3 part of Radix Notoginseng, 10 parts of Cortex Magnoliae Officinalis, 0.3 part of Radix Aucklandiae (Radix Vladimiriae), 0.3 part in Radix Glycyrrhizae.
Technology: the flavour of a drug in will writing out a prescription are chosen only, dry, pulverize, and mixing after the difference weighing, the packing pouch forms.
Embodiment 2
Prescription:
80 parts of Fructus Amomis, 40 parts of Flos Caryophyllis, 90 parts of Os Sepiae, 60 parts of Fructus Piperis Longi, 70 parts of Concha Arcaes, 40 parts of Herba Taraxaci, 2.0 parts of Fructus Evodiae, 0.9 part of Radix Notoginseng, 40 parts of Cortex Magnoliae Officinalis, 0.9 part of Radix Aucklandiae (Radix Vladimiriae), 0.9 part in Radix Glycyrrhizae.
Technology: same with embodiment 1.
Embodiment 3
Prescription:
60 parts of Fructus Amomis, 25 parts of Flos Caryophyllis, 70 parts of Os Sepiae, 40 parts of Fructus Piperis Longi, 50 parts of Concha Arcaes, 25 parts of Herba Taraxaci, 1.2 parts of Fructus Evodiae, 0.6 part of Radix Notoginseng, 25 parts of Cortex Magnoliae Officinalis, 0.5 part of Radix Aucklandiae (Radix Vladimiriae), 0.6 part in Radix Glycyrrhizae.
Technology: same with embodiment 1.

Claims (3)

1, a kind of Chinese medicine composition for the treatment of digestive system and ulcer is prepared from by the raw material extraction process by water routinely of following weight than part:
Fructus Amomi 40-80 part, Flos Caryophylli 10-40 part, Os Sepiae 50-90 part, Fructus Piperis Longi 20-60 part, Concha Arcae 30-70 part, Herba Taraxaci 10-40 part, Fructus Evodiae 0.5-2.0 part, Radix Notoginseng 0.3-0.9 part, Cortex Magnoliae Officinalis 10-40 part, Radix Aucklandiae (Radix Vladimiriae) 0.3-0.9 part, Radix Glycyrrhizae 0.3-0.9 part.
2, treat the Chinese medicine composition of digestive system and ulcer according to claim 1, it is characterized in that: be equipped with adjuvant commonly used on the pharmaceutics, be prepared into any dosage form on the pharmaceutics.
3, treat the Chinese medicine composition of digestive system and ulcer according to claim 1, it is characterized in that: described each ratio component is prepared into powder by the conventional process for preparing powder.
CNB2005100431639A 2005-08-25 2005-08-25 Chinese medicine composition for treating digestive system ulcer Expired - Fee Related CN100339125C (en)

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CN100339125C true CN100339125C (en) 2007-09-26

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104436074A (en) * 2014-12-24 2015-03-25 赵红 Traditional Chinese medicine preparation for treating peptic ulcer and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1435201A (en) * 2002-02-02 2003-08-13 王桂英 Medicine for treating gastritis and gastric ulcer
CN1579497A (en) * 2004-05-20 2005-02-16 杨建新 Traditional Chinese medicinal preparation for treating iternal-external ulcer and its preparation method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1435201A (en) * 2002-02-02 2003-08-13 王桂英 Medicine for treating gastritis and gastric ulcer
CN1579497A (en) * 2004-05-20 2005-02-16 杨建新 Traditional Chinese medicinal preparation for treating iternal-external ulcer and its preparation method

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
疗疡汤治疗胃、十二指肠溃疡120例 高丕富,实用中西医结合杂志,第7卷第12期 1994 *
西青果药材及提取物液相指纹 颜玉贞等,中成药,第26期 2004 *

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