CL2023003488A1 - Composición que comprende un éster de alfa-tocoferol para reducir el riesgo de parto prematuro - Google Patents
Composición que comprende un éster de alfa-tocoferol para reducir el riesgo de parto prematuroInfo
- Publication number
- CL2023003488A1 CL2023003488A1 CL2023003488A CL2023003488A CL2023003488A1 CL 2023003488 A1 CL2023003488 A1 CL 2023003488A1 CL 2023003488 A CL2023003488 A CL 2023003488A CL 2023003488 A CL2023003488 A CL 2023003488A CL 2023003488 A1 CL2023003488 A1 CL 2023003488A1
- Authority
- CL
- Chile
- Prior art keywords
- risk
- composition
- reduce
- alpha
- premature birth
- Prior art date
Links
- 208000005107 Premature Birth Diseases 0.000 title abstract 2
- 206010036590 Premature baby Diseases 0.000 title abstract 2
- -1 alpha-tocopherol ester Chemical class 0.000 title abstract 2
- GVJHHUAWPYXKBD-IEOSBIPESA-N (R)-alpha-Tocopherol Natural products OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 title 1
- 229940087168 alpha tocopherol Drugs 0.000 title 1
- 229960000984 tocofersolan Drugs 0.000 title 1
- 239000002076 α-tocopherol Substances 0.000 title 1
- 235000004835 α-tocopherol Nutrition 0.000 title 1
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 abstract 3
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 abstract 2
- 229930003427 Vitamin E Natural products 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- ZAKOWWREFLAJOT-UHFFFAOYSA-N d-alpha-Tocopheryl acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 abstract 2
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 abstract 2
- 229940046009 vitamin E Drugs 0.000 abstract 2
- 235000019165 vitamin E Nutrition 0.000 abstract 2
- 239000011709 vitamin E Substances 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 210000000214 mouth Anatomy 0.000 abstract 1
- 229940042585 tocopherol acetate Drugs 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
Abstract
Una composición para aplicación tópica en la cavidad bucal, para usarse en mujeres embarazadas para reducir el riesgo de parto prematuro, que comprende un éster de vitamina E con un ácido carboxílico de fórmula R-COOH, en el que R es un radical alquilo que tiene de 1 a 19 átomos de carbono, o un radical alquenilo o alquinilo que tiene de 2 a 19 átomos de carbono, y un vehículo oleoso; el éster de vitamina E se puede seleccionar de acetato de vitamina E, n-propionato o lineoleato, preferiblemente acetato de alfa-tocoferilo.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT102021000013898A IT202100013898A1 (it) | 2021-05-27 | 2021-05-27 | Composizione comprendente un estere di alfa-tocoferolo per la riduzione del rischio di parto pretermine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2023003488A1 true CL2023003488A1 (es) | 2024-05-24 |
Family
ID=77801802
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2023003488A CL2023003488A1 (es) | 2021-05-27 | 2023-11-23 | Composición que comprende un éster de alfa-tocoferol para reducir el riesgo de parto prematuro |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20240261255A1 (es) |
| EP (1) | EP4346900A1 (es) |
| AU (1) | AU2022283507A1 (es) |
| BR (1) | BR112023024736A2 (es) |
| CA (1) | CA3219732A1 (es) |
| CL (1) | CL2023003488A1 (es) |
| GE (1) | GEP20247621B (es) |
| IT (1) | IT202100013898A1 (es) |
| MX (1) | MX2023013918A (es) |
| WO (1) | WO2022248269A1 (es) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3763075B2 (ja) | 1998-04-24 | 2006-04-05 | サンスター株式会社 | 歯周病の予防又は治療用の食品組成物、口腔用組成物及び医薬組成物 |
| WO2011150393A2 (en) | 2010-05-28 | 2011-12-01 | Bmg Hematology Llc | Methods for improving maternal and fetal health |
| CN101999426B (zh) * | 2010-09-25 | 2011-11-30 | 昆明医学院 | 孕妇营养饼干 |
| IL230419A0 (en) | 2013-05-23 | 2014-04-30 | Naveh Pharma 1996 Ltd | Products containing magnesium and their uses |
| CN107847506A (zh) * | 2015-06-22 | 2018-03-27 | 来普卡公司 | 含17‑羟基孕酮酯的口服组合物和相关方法 |
| WO2017081725A1 (ja) * | 2015-11-09 | 2017-05-18 | 花王株式会社 | 口腔用組成物 |
| TW201924696A (zh) | 2017-12-01 | 2019-07-01 | 瑞士商耐斯泰克公司 | 母體補充劑 |
-
2021
- 2021-05-27 IT IT102021000013898A patent/IT202100013898A1/it unknown
-
2022
- 2022-05-16 MX MX2023013918A patent/MX2023013918A/es unknown
- 2022-05-16 EP EP22729540.9A patent/EP4346900A1/en active Pending
- 2022-05-16 GE GEAP202216392A patent/GEP20247621B/en unknown
- 2022-05-16 WO PCT/EP2022/063177 patent/WO2022248269A1/en active Application Filing
- 2022-05-16 US US18/562,492 patent/US20240261255A1/en active Pending
- 2022-05-16 AU AU2022283507A patent/AU2022283507A1/en active Pending
- 2022-05-16 BR BR112023024736A patent/BR112023024736A2/pt unknown
- 2022-05-16 CA CA3219732A patent/CA3219732A1/en active Pending
-
2023
- 2023-11-23 CL CL2023003488A patent/CL2023003488A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2022248269A1 (en) | 2022-12-01 |
| IT202100013898A1 (it) | 2022-11-27 |
| US20240261255A1 (en) | 2024-08-08 |
| BR112023024736A2 (pt) | 2024-02-15 |
| AU2022283507A1 (en) | 2023-11-30 |
| EP4346900A1 (en) | 2024-04-10 |
| MX2023013918A (es) | 2023-12-08 |
| GEP20247621B (en) | 2024-05-13 |
| CA3219732A1 (en) | 2022-12-01 |
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