CL2022002699A1 - Métodos para tratar la esclerosis múltiple recidivante utilizando un inhibidor de la tirosina cinasa de bruton. - Google Patents

Métodos para tratar la esclerosis múltiple recidivante utilizando un inhibidor de la tirosina cinasa de bruton.

Info

Publication number
CL2022002699A1
CL2022002699A1 CL2022002699A CL2022002699A CL2022002699A1 CL 2022002699 A1 CL2022002699 A1 CL 2022002699A1 CL 2022002699 A CL2022002699 A CL 2022002699A CL 2022002699 A CL2022002699 A CL 2022002699A CL 2022002699 A1 CL2022002699 A1 CL 2022002699A1
Authority
CL
Chile
Prior art keywords
methods
multiple sclerosis
tyrosine kinase
kinase inhibitor
relapsing multiple
Prior art date
Application number
CL2022002699A
Other languages
English (en)
Inventor
Hideki Garren
Edmond Huatung Teng
Aurelien Viaccoz
Buedingen Hans-Christian Von
Original Assignee
Genentech Inc
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc, Hoffmann La Roche filed Critical Genentech Inc
Publication of CL2022002699A1 publication Critical patent/CL2022002699A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

En la presente se proporcionan métodos para tratar la esclerosis múltiple recidivante (RMS) en un sujeto que lo necesita, al administrar al sujeto alrededor de 200 mg de fenebrutinib dos veces por día, o una cantidad equivalente de una sal farmacéuticamente aceptable de este.
CL2022002699A 2020-04-03 2022-09-30 Métodos para tratar la esclerosis múltiple recidivante utilizando un inhibidor de la tirosina cinasa de bruton. CL2022002699A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063005095P 2020-04-03 2020-04-03
US202063051767P 2020-07-14 2020-07-14

Publications (1)

Publication Number Publication Date
CL2022002699A1 true CL2022002699A1 (es) 2023-03-31

Family

ID=75625678

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2022002699A CL2022002699A1 (es) 2020-04-03 2022-09-30 Métodos para tratar la esclerosis múltiple recidivante utilizando un inhibidor de la tirosina cinasa de bruton.

Country Status (13)

Country Link
US (1) US20230149395A1 (es)
EP (1) EP4125906A1 (es)
JP (1) JP2023520469A (es)
KR (1) KR20220163986A (es)
CN (1) CN115916205A (es)
AU (1) AU2021249129A1 (es)
BR (1) BR112022019846A2 (es)
CA (1) CA3177390A1 (es)
CL (1) CL2022002699A1 (es)
IL (1) IL296990A (es)
MX (1) MX2022012310A (es)
TW (1) TW202203925A (es)
WO (1) WO2021202825A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230171449A (ko) 2021-05-14 2023-12-20 록쏘 온콜로지, 인코포레이티드 브루톤 티로신 키나제 억제제의 공결정질 형태
CN114028393B (zh) * 2021-11-07 2023-07-18 天津医科大学 阿帕替尼在制备治疗多发性硬化症药物的用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA111756C2 (uk) 2011-11-03 2016-06-10 Ф. Хоффманн-Ля Рош Аг Сполуки гетероарилпіридону та азапіридону як інгібітори тирозинкінази брутона
AU2017227929B2 (en) 2016-02-29 2022-06-30 F. Hoffmann-La Roche Ag Dosage form compositions comprising an inhibitor of Bruton's tyrosine kinase

Also Published As

Publication number Publication date
AU2021249129A1 (en) 2022-10-20
BR112022019846A2 (pt) 2022-11-22
WO2021202825A1 (en) 2021-10-07
CA3177390A1 (en) 2021-10-07
JP2023520469A (ja) 2023-05-17
TW202203925A (zh) 2022-02-01
MX2022012310A (es) 2022-10-27
EP4125906A1 (en) 2023-02-08
US20230149395A1 (en) 2023-05-18
KR20220163986A (ko) 2022-12-12
CN115916205A (zh) 2023-04-04
IL296990A (en) 2022-12-01

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