CL2022002642A1 - Medicamentos para fibrosis pulmonar que contienen derivado de pirazol - Google Patents

Medicamentos para fibrosis pulmonar que contienen derivado de pirazol

Info

Publication number
CL2022002642A1
CL2022002642A1 CL2022002642A CL2022002642A CL2022002642A1 CL 2022002642 A1 CL2022002642 A1 CL 2022002642A1 CL 2022002642 A CL2022002642 A CL 2022002642A CL 2022002642 A CL2022002642 A CL 2022002642A CL 2022002642 A1 CL2022002642 A1 CL 2022002642A1
Authority
CL
Chile
Prior art keywords
pulmonary fibrosis
drugs
pyrazole derivative
containing pyrazole
fibrosis containing
Prior art date
Application number
CL2022002642A
Other languages
English (en)
Spanish (es)
Inventor
Jin Lee Soo
Hwan Moon Sung
Yu Hyunkyung
Goh Yoo-Kyung
Original Assignee
Aptabio Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020210036863A external-priority patent/KR102386097B1/ko
Application filed by Aptabio Therapeutics Inc filed Critical Aptabio Therapeutics Inc
Publication of CL2022002642A1 publication Critical patent/CL2022002642A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CL2022002642A 2020-04-13 2022-09-27 Medicamentos para fibrosis pulmonar que contienen derivado de pirazol CL2022002642A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20200044598 2020-04-13
KR1020210036863A KR102386097B1 (ko) 2020-04-13 2021-03-22 피라졸 유도체의 폐섬유증 치료제

Publications (1)

Publication Number Publication Date
CL2022002642A1 true CL2022002642A1 (es) 2023-06-16

Family

ID=78083982

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2022002642A CL2022002642A1 (es) 2020-04-13 2022-09-27 Medicamentos para fibrosis pulmonar que contienen derivado de pirazol

Country Status (12)

Country Link
US (1) US12616684B2 (enExample)
EP (1) EP4137134A4 (enExample)
JP (1) JP7539485B2 (enExample)
KR (2) KR102567012B1 (enExample)
CN (1) CN115427039B (enExample)
AU (1) AU2021255160B2 (enExample)
BR (1) BR112022020649A2 (enExample)
CA (1) CA3172596A1 (enExample)
CL (1) CL2022002642A1 (enExample)
CO (1) CO2022014273A2 (enExample)
MX (1) MX2022012726A (enExample)
WO (1) WO2021210799A1 (enExample)

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20040094464A (ko) * 2003-05-02 2004-11-10 학교법인 이화학당 피리디닐 피라졸 유도체
KR20120054077A (ko) 2009-08-21 2012-05-29 길리아드 바이오로직스, 인크. 폐 섬유증 장애의 치료를 위한 방법 및 조성물
WO2011028043A2 (ko) 2009-09-02 2011-03-10 이화여자대학교 산학협력단 피라졸 유도체, 이의 제조방법 및 이를 포함하는 골다공증 예방 및 치료용 조성물
KR101302315B1 (ko) * 2011-07-19 2013-08-30 이화여자대학교 산학협력단 피라졸 유도체를 포함하는 호흡기 질환 예방 및 치료용 조성물
KR101633957B1 (ko) 2012-08-27 2016-06-27 이화여자대학교 산학협력단 피라졸 유도체를 포함하는 신장질환 예방 또는 치료용 조성물
US10548911B2 (en) * 2014-06-16 2020-02-04 University Of Rochester Small molecule anti-scarring agents
US11096952B2 (en) * 2016-02-02 2021-08-24 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Chemicals and methods to prevent and treat TGF-beta mediated activation of fibroblasts to reduce and treat cancer and fibrosis
WO2017192304A1 (en) 2016-05-02 2017-11-09 Inception 1, Inc. Arylcarboxamides and uses thereof
CA3046158A1 (en) 2017-01-27 2018-08-02 Genfit Pharmaceutical compositions for combination therapy
KR101821593B1 (ko) 2017-02-23 2018-01-25 압타바이오 주식회사 안질환 치료제
IL268751B (en) 2017-03-13 2022-08-01 Genfit Pharmaceutical preparations for combined treatment
CN110536683A (zh) 2017-04-18 2019-12-03 基恩菲特公司 包含PPAR激动剂如伊拉非诺和乙酰CoA羧化酶ACC抑制剂的组合
KR101856444B1 (ko) 2017-04-20 2018-05-10 압타바이오 주식회사 3-페닐-4-프로필-1-(피리딘-2-일)-1h-피라졸-5-올 염산염의 신규 결정형 고체 화합물
KR101840702B1 (ko) * 2017-11-01 2018-03-22 압타바이오 주식회사 간질환 치료제
TWI815938B (zh) 2018-08-01 2023-09-21 日商日本化藥股份有限公司 具有n-烷基的芳香族胺樹脂、硬化性樹脂組成物及其硬化物
EP3628669A1 (en) 2018-09-28 2020-04-01 GenKyoTex Suisse SA Novel compounds as nadph oxidase inhibitors
KR102207340B1 (ko) 2018-10-19 2021-01-22 한남대학교 산학협력단 표면 개질된 다공성 탄소복합소재 및 그 제조방법
CN109912600B (zh) * 2019-02-22 2021-08-03 四川大学华西医院 一种防治肺纤维化的咪唑并嘧啶类衍生物及其应用
MX2022012472A (es) 2020-04-08 2022-12-15 Aptabio Therapeutics Inc Agente para el tratamiento de lesion renal aguda inducida por medio de contraste.
WO2021263281A2 (en) * 2020-06-26 2021-12-30 Ann And Robert H. Lurie Children's Hospital Of Chicago Methods and compositions for the treatment of covid-19 and associated respiratory distress and multi-organ failure, sepsis, acute respiratory distress syndrome, and cordiovascular diseases
UY39671A (es) 2021-03-15 2022-10-31 Novartis Ag Derivados de pirazolopiridina y sus usos.

Also Published As

Publication number Publication date
WO2021210799A1 (ko) 2021-10-21
JP7539485B2 (ja) 2024-08-23
KR20210146871A (ko) 2021-12-06
EP4137134A1 (en) 2023-02-22
US20230148365A1 (en) 2023-05-11
MX2022012726A (es) 2022-11-07
KR20220039687A (ko) 2022-03-29
CN115427039B (zh) 2025-04-04
BR112022020649A2 (pt) 2022-11-29
AU2021255160B2 (en) 2024-02-01
CA3172596A1 (en) 2021-10-21
JP2023522628A (ja) 2023-05-31
EP4137134A4 (en) 2024-08-07
KR102567012B1 (ko) 2023-08-14
CO2022014273A2 (es) 2022-10-21
AU2021255160A1 (en) 2022-10-06
US12616684B2 (en) 2026-05-05
CN115427039A (zh) 2022-12-02

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