CL2022001227A1 - Agonistas del receptor npy2 - Google Patents

Agonistas del receptor npy2

Info

Publication number
CL2022001227A1
CL2022001227A1 CL2022001227A CL2022001227A CL2022001227A1 CL 2022001227 A1 CL2022001227 A1 CL 2022001227A1 CL 2022001227 A CL2022001227 A CL 2022001227A CL 2022001227 A CL2022001227 A CL 2022001227A CL 2022001227 A1 CL2022001227 A1 CL 2022001227A1
Authority
CL
Chile
Prior art keywords
receptor agonists
analogues
npy2 receptor
relates
pyy
Prior art date
Application number
CL2022001227A
Other languages
English (en)
Spanish (es)
Inventor
Wilhelm Haebel Peter
Brennauer Albert
Stahl Madsen Charlotte
Ljungberg Pedersen Soren
Peters Stefan
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of CL2022001227A1 publication Critical patent/CL2022001227A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/2271Neuropeptide Y

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CL2022001227A 2019-11-11 2022-05-10 Agonistas del receptor npy2 CL2022001227A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP19208394 2019-11-11

Publications (1)

Publication Number Publication Date
CL2022001227A1 true CL2022001227A1 (es) 2023-02-03

Family

ID=68531488

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2022001227A CL2022001227A1 (es) 2019-11-11 2022-05-10 Agonistas del receptor npy2

Country Status (20)

Country Link
US (3) US20210139548A1 (OSRAM)
EP (1) EP4058047A1 (OSRAM)
JP (1) JP2023500895A (OSRAM)
KR (1) KR20220100925A (OSRAM)
CN (1) CN114641303A (OSRAM)
AR (1) AR120440A1 (OSRAM)
AU (1) AU2020384729A1 (OSRAM)
CA (1) CA3156452A1 (OSRAM)
CL (1) CL2022001227A1 (OSRAM)
CO (1) CO2022006046A2 (OSRAM)
CR (1) CR20220206A (OSRAM)
DO (1) DOP2022000097A (OSRAM)
EC (1) ECSP22037660A (OSRAM)
IL (1) IL292601A (OSRAM)
JO (1) JOP20220110A1 (OSRAM)
MX (1) MX2022005661A (OSRAM)
PE (1) PE20221168A1 (OSRAM)
PH (1) PH12022551101A1 (OSRAM)
TW (1) TWI864155B (OSRAM)
WO (1) WO2021094259A1 (OSRAM)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114641303A (zh) 2019-11-11 2022-06-17 勃林格殷格翰国际有限公司 Npy2受体激动剂
PE20231566A1 (es) * 2020-08-07 2023-10-04 Boehringer Ingelheim Int Agonistas del receptor npy2 solubles
CN119677527A (zh) 2022-08-18 2025-03-21 勃林格殷格翰国际有限公司 包含长效glp-1/胰高血糖素及npy2受体激动剂的组合疗法
US20240247080A1 (en) * 2022-12-21 2024-07-25 Boehringer Ingelheim International Gmbh Glp1/gip/npy2 receptor triple agonists

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ579621A (en) 2004-02-11 2011-03-31 Amylin Pharmaceuticals Inc Hybrid polypeptides with selectable properties
EA011860B1 (ru) 2004-03-17 2009-06-30 7ТиЭм ФАРМА А/С Селективные агонисты рецептора y2 для терапевтического воздействия
SG158141A1 (en) 2004-12-13 2010-01-29 Amylin Pharmaceuticals Inc Pancreatic polypeptide family motifs, polypeptides and methods comprising the same
EP1962959B1 (en) 2005-12-07 2012-03-14 F. Hoffmann-La Roche AG Neuropeptide-2 receptor-agonists
US8454971B2 (en) 2007-02-15 2013-06-04 Indiana University Research And Technology Corporation Glucagon/GLP-1 receptor co-agonists
DK2158214T3 (da) 2007-06-15 2011-12-05 Zealand Pharma As Glukagonanaloger
CN101939022A (zh) 2007-11-14 2011-01-05 安米林药品公司 治疗肥胖以及肥胖相关疾病和病症的方法
FR2934058B1 (fr) 2008-07-15 2010-09-24 Centre Nat Rech Scient Dispositif de projection interferometrique a trois ouvertures pour produire une tache constituee de structures fines
AU2008365557A1 (en) 2008-12-15 2011-07-21 Zealand Pharma A/S Glucagon analogues
AU2008365555B2 (en) 2008-12-15 2016-01-14 Zealand Pharma A/S Glucagon analogues
PL2370460T3 (pl) 2008-12-15 2014-09-30 Zealand Pharma As Analogi glukagonu
BRPI0823377A2 (pt) 2008-12-15 2016-09-27 Zealand Pharma As análogos de glucagon
MX2012000564A (es) 2009-07-13 2012-04-11 Zealand Pharma As Analogos de glucagon acilados.
WO2011033068A1 (en) 2009-09-18 2011-03-24 Novo Nordisk A/S Long-acting y2 receptor agonists
JP2013510829A (ja) * 2009-11-13 2013-03-28 ノヴォ ノルディスク アー/エス 長時間作用型y2受容体アゴニスト
UY33462A (es) 2010-06-23 2012-01-31 Zealand Pharma As Analogos de glucagon
EA201291234A1 (ru) 2010-06-24 2013-07-30 Зилэнд Фарма А/С Аналоги глюкагона
RU2669999C2 (ru) 2011-06-10 2018-10-17 Ново Нордиск А/С Полипептиды
US20130316941A1 (en) 2011-12-23 2013-11-28 Boehringer Ingelheim International Gmbh Glucagon analogues
MX356641B (es) 2012-05-03 2018-06-07 Zealand Pharma As Compuestos agonistas dobles de gip-glp-1 y procedimientos.
TWI608013B (zh) 2012-09-17 2017-12-11 西蘭製藥公司 升糖素類似物
JP2016519130A (ja) 2013-05-02 2016-06-30 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited 治療ペプチド
AR097701A1 (es) 2013-09-19 2016-04-13 Zealand Pharma As Análogos de amilina
WO2015055801A1 (en) 2013-10-17 2015-04-23 Zealand Pharma A/S Acylated glucagon analogues
US9988429B2 (en) 2013-10-17 2018-06-05 Zealand Pharma A/S Glucagon analogues
TR201902516T4 (tr) 2013-11-06 2019-03-21 Zealand Pharma As Glukagon-glp-1-gıp üçlü agonist bileşikleri.
SI3321278T1 (sl) 2013-11-14 2019-04-30 Keybioscience Ag Mimetiki kalcitonina za zdravljenje bolezni in motenj
CN105722526B (zh) 2013-11-15 2020-12-08 诺和诺德股份有限公司 选择性pyy化合物及其用途
JP6629198B2 (ja) * 2013-11-15 2020-01-15 ノヴォ ノルディスク アー/エス 35位にβ−ホモアルギニン置換を有するHPYY(1−36)
AR103954A1 (es) 2015-03-18 2017-06-14 Zealand Pharma As Análogos de amilina
CN107636010B (zh) 2015-04-16 2021-10-01 西兰制药公司 酰化胰高血糖素类似物
RU2726777C2 (ru) * 2015-06-12 2020-07-15 Ново Нордиск А/С Селективные соединения пептида yy и их применения
WO2016198624A1 (en) 2015-06-12 2016-12-15 Sanofi Exendin-4 derivatives as trigonal glp-1/glucagon/gip receptor agonists
PL3398961T3 (pl) 2015-12-31 2022-09-26 Hanmi Pharm. Co., Ltd. Potrójny aktywator aktywujący receptory glukagonu, glp-1 i gip
EP3452088A4 (en) 2016-05-03 2020-04-15 The Scripps Research Institute TRKB AGONIST ANTIBODIES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES
AR109514A1 (es) 2016-09-09 2018-12-19 Zealand Pharma As Análogos de amilina
JOP20190095A1 (ar) 2016-10-27 2019-04-28 Janssen Pharmaceutica Nv مركبات ببتيد تيروسين-تيروسين الحلقية كمعدلات لمستقبلات الببتيد العصبي y
TW201833132A (zh) 2016-12-02 2018-09-16 法商賽諾菲公司 作為肽類glp1/升糖素/gip三重受體激動劑之新穎化合物
TW201833131A (zh) 2016-12-02 2018-09-16 法商賽諾菲公司 作為胜肽類glp1/升糖素/gip受體促效劑之新化合物
CN108289005B (zh) 2017-01-09 2021-06-29 中兴通讯股份有限公司 信令发送、接收方法及装置
GB201704429D0 (en) 2017-03-21 2017-05-03 Keybioscience Ag Calcitonin mimetics for treating diseases and disorders
US10793634B2 (en) 2017-06-09 2020-10-06 Boehringer Ingelheim International Gmbh Anti-TrkB antibodies
GB201720188D0 (en) 2017-12-04 2018-01-17 Imperial Innovations Ltd Analogues of PYY
TWI865836B (zh) * 2018-11-01 2024-12-11 美商美國禮來大藥廠 蛋白質酪胺酸-酪胺酸類似物及其使用方法
CN114641303A (zh) 2019-11-11 2022-06-17 勃林格殷格翰国际有限公司 Npy2受体激动剂

Also Published As

Publication number Publication date
AR120440A1 (es) 2022-02-16
PH12022551101A1 (en) 2023-11-13
US20210139548A1 (en) 2021-05-13
US12054525B2 (en) 2024-08-06
EP4058047A1 (en) 2022-09-21
KR20220100925A (ko) 2022-07-18
JP2023500895A (ja) 2023-01-11
MX2022005661A (es) 2022-09-07
CO2022006046A2 (es) 2022-05-20
TW202134263A (zh) 2021-09-16
WO2021094259A1 (en) 2021-05-20
AU2020384729A1 (en) 2022-04-14
CR20220206A (es) 2022-06-16
CN114641303A (zh) 2022-06-17
US20230340039A1 (en) 2023-10-26
CA3156452A1 (en) 2021-05-20
US20250002544A1 (en) 2025-01-02
JOP20220110A1 (ar) 2023-01-30
DOP2022000097A (es) 2022-06-15
ECSP22037660A (es) 2022-06-30
TWI864155B (zh) 2024-12-01
PE20221168A1 (es) 2022-07-25
IL292601A (en) 2022-07-01

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