CL2021002070A1 - Composiciones farmacéuticas que comprenden meloxicam. - Google Patents
Composiciones farmacéuticas que comprenden meloxicam.Info
- Publication number
- CL2021002070A1 CL2021002070A1 CL2021002070A CL2021002070A CL2021002070A1 CL 2021002070 A1 CL2021002070 A1 CL 2021002070A1 CL 2021002070 A CL2021002070 A CL 2021002070A CL 2021002070 A CL2021002070 A CL 2021002070A CL 2021002070 A1 CL2021002070 A1 CL 2021002070A1
- Authority
- CL
- Chile
- Prior art keywords
- meloxicam
- migraine
- rizatriptan
- pain
- administered
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Abstract
Se describe en la presente composiciones que comprenden un NSAID como meloxicam y/o rizatriptán en combinación con una ciclodextrina y/o un carbonato o un bicarbonato. Estas composiciones pueden ser oralmente administradas, por ejemplo, para mejorar la biodisponibilidad o farmacocinéticas del NSAID para el tratamiento de dolor como migraña, artritis, y otras afecciones. También se describen aquí métodos para tratar el dolor, como migraña, que comprenden administrar meloxicam y rizatriptán a un ser humano que sufre de dolor, como migraña. Para la migraña, estos métodos pueden ser particularmente útiles cuando el meloxicam y el rizatriptán son administrados mientras el ser humano está sufriendo de un ataque agudo de dolor de migraña o aura de migraña. En algunas modalidades, la combinación de meloxicam y rizatriptán pueden ser administrados en una forma que resulta en una Tmáx de meloxicam de 3 horas o menos.
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962802198P | 2019-02-06 | 2019-02-06 | |
US201962803756P | 2019-02-11 | 2019-02-11 | |
US201962835613P | 2019-04-18 | 2019-04-18 | |
US201962846311P | 2019-05-10 | 2019-05-10 | |
US201962860705P | 2019-06-12 | 2019-06-12 | |
US201962895933P | 2019-09-04 | 2019-09-04 | |
US201962895956P | 2019-09-04 | 2019-09-04 | |
US201962955905P | 2019-12-31 | 2019-12-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2021002070A1 true CL2021002070A1 (es) | 2022-04-01 |
Family
ID=71947112
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2021002070A CL2021002070A1 (es) | 2019-02-06 | 2021-08-05 | Composiciones farmacéuticas que comprenden meloxicam. |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP3920909A4 (es) |
JP (3) | JP7237386B2 (es) |
KR (1) | KR20210118880A (es) |
CN (1) | CN113423397A (es) |
AU (2) | AU2020218253B2 (es) |
BR (1) | BR112021015467A2 (es) |
CA (2) | CA3213549A1 (es) |
CL (1) | CL2021002070A1 (es) |
CO (1) | CO2021010380A2 (es) |
CR (1) | CR20210420A (es) |
EC (1) | ECSP21060962A (es) |
IL (1) | IL285389A (es) |
MA (1) | MA54904A (es) |
MX (1) | MX2021009435A (es) |
PE (1) | PE20212157A1 (es) |
SG (1) | SG11202107926XA (es) |
WO (1) | WO2020163620A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116887838A (zh) * | 2020-12-31 | 2023-10-13 | 艾克萨姆治疗公司 | 包含美洛昔康的药物组合物 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1126841B1 (en) | 1998-11-02 | 2004-12-15 | Merck & Co., Inc. | Combinations of a 5ht1b/1d agonist and a selective cox-2 inhibitor for the treatment of migraine |
US20040214861A1 (en) * | 2003-03-28 | 2004-10-28 | Pharmacia Corporation | Compositions of a cyclooxygenase-2 selective inhibitors and 5-HT1B1D antagonists for the treatment and prevention of migraine |
US8268791B2 (en) * | 2004-08-25 | 2012-09-18 | Aegis Therapeutics, Llc. | Alkylglycoside compositions for drug administration |
US20090068262A1 (en) * | 2007-04-04 | 2009-03-12 | Ilan Zalit | Rapid dissolution of combination products |
PL3100728T3 (pl) | 2009-05-13 | 2020-05-18 | Cydex Pharmaceuticals, Inc. | Kompozycje farmaceutyczne zawierające prasugrel i pochodne cyklodekstryny oraz sposoby ich wytwarzania i zastosowania |
KR20230098923A (ko) * | 2015-02-10 | 2023-07-04 | 액섬 테라퓨틱스, 인크. | 멜록시캄을 포함하는 약학 조성물 |
US9821075B2 (en) * | 2015-02-10 | 2017-11-21 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
MX2017010304A (es) | 2015-11-25 | 2018-06-19 | Axsome Therapeutics Inc | Composiciones farmaceuticas que comprenden meloxicam. |
KR20190066607A (ko) * | 2016-09-23 | 2019-06-13 | 테바 파마슈티컬스 인터내셔널 게엠베하 | 불응성 편두통의 치료 |
US10471014B2 (en) * | 2017-01-04 | 2019-11-12 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam |
EP3565550B1 (en) | 2017-01-04 | 2020-10-28 | Axsome Therapeutics, Inc. | Pharmaceutical compositions comprising meloxicam and rizatriptan |
CN110612103B (zh) | 2017-05-10 | 2023-08-22 | 艾克萨姆治疗公司 | 包含美洛昔康的药物组合物 |
-
2020
- 2020-02-06 EP EP20752178.2A patent/EP3920909A4/en active Pending
- 2020-02-06 KR KR1020217026519A patent/KR20210118880A/ko not_active Application Discontinuation
- 2020-02-06 AU AU2020218253A patent/AU2020218253B2/en active Active
- 2020-02-06 MA MA054904A patent/MA54904A/fr unknown
- 2020-02-06 CN CN202080012487.9A patent/CN113423397A/zh active Pending
- 2020-02-06 BR BR112021015467-1A patent/BR112021015467A2/pt unknown
- 2020-02-06 WO PCT/US2020/017046 patent/WO2020163620A1/en unknown
- 2020-02-06 CA CA3213549A patent/CA3213549A1/en active Pending
- 2020-02-06 PE PE2021001288A patent/PE20212157A1/es unknown
- 2020-02-06 JP JP2021545919A patent/JP7237386B2/ja active Active
- 2020-02-06 MX MX2021009435A patent/MX2021009435A/es unknown
- 2020-02-06 CA CA3128940A patent/CA3128940C/en active Active
- 2020-02-06 CR CR20210420A patent/CR20210420A/es unknown
- 2020-02-06 SG SG11202107926XA patent/SG11202107926XA/en unknown
-
2021
- 2021-08-04 IL IL285389A patent/IL285389A/en unknown
- 2021-08-05 CL CL2021002070A patent/CL2021002070A1/es unknown
- 2021-08-06 CO CONC2021/0010380A patent/CO2021010380A2/es unknown
- 2021-08-17 EC ECSENADI202160962A patent/ECSP21060962A/es unknown
-
2023
- 2023-02-21 JP JP2023025218A patent/JP7420990B2/ja active Active
- 2023-04-27 AU AU2023202545A patent/AU2023202545A1/en active Pending
-
2024
- 2024-01-11 JP JP2024002855A patent/JP2024026732A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2022519670A (ja) | 2022-03-24 |
CA3128940A1 (en) | 2020-08-13 |
WO2020163620A1 (en) | 2020-08-13 |
ECSP21060962A (es) | 2021-11-30 |
CO2021010380A2 (es) | 2021-09-30 |
MX2021009435A (es) | 2021-09-10 |
CA3213549A1 (en) | 2020-08-13 |
JP7420990B2 (ja) | 2024-01-23 |
CA3128940C (en) | 2023-11-07 |
BR112021015467A2 (pt) | 2021-10-05 |
AU2020218253A1 (en) | 2021-08-12 |
PE20212157A1 (es) | 2021-11-09 |
CR20210420A (es) | 2021-12-22 |
EP3920909A4 (en) | 2022-11-30 |
EP3920909A1 (en) | 2021-12-15 |
JP2023062144A (ja) | 2023-05-02 |
JP2024026732A (ja) | 2024-02-28 |
AU2020218253B2 (en) | 2023-02-23 |
KR20210118880A (ko) | 2021-10-01 |
CN113423397A (zh) | 2021-09-21 |
SG11202107926XA (en) | 2021-08-30 |
JP7237386B2 (ja) | 2023-03-13 |
MA54904A (fr) | 2021-12-15 |
IL285389A (en) | 2021-09-30 |
AU2023202545A1 (en) | 2023-05-18 |
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